Fatty Acids

Research Publications

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Roy S, Brasky TM, Belury MA, Krishnan S, Cole RM, Marian C, Yee LD, Llanos AA, Freudenheim JL, Shields PG. 2015. Associations of erythrocyte ω-3 fatty acids with biomarkers of ω-3 fatty acids and inflammation in breast tissue. Int J Cancer. 137(12), 2934–46.

Straka S, Lester JL, Cole RM, Andridge RR, Puchala S, Rose AM, Clinton SK, Belury MA, Yee LD. 2015. Incorporation of eicosapentaenioic and docosahexaenoic acids into breast adipose tissue of women at high risk of breast cancer: A randomized clinical trial of dietary fish and n-3 fatty acid capsules. Mol Nutr Food Res. 59(4):763-72.

Shen Q, Riedl KM, Cole RM, Lehman C, Xu L, Alder H, Belury MA, Schwartz SJ, Ziouzenkova O. 2014. Egg yolks inhibit activation of NF-κB and expression of its target genes in adipocytes after partial delipidation. J Agric Food Chem. 76(8):650-8.

Carta G, Murru E, Cordeddu L, Ortiz B, Giordano E, Belury MA, Quadro L, Banni S. 2014. Metabolic interactions between vitamin A and conjugated linoleic acid. Nutrients. 6(3):1262–72.

Failla ML, Chitchumronchokchai C, Ferruzzi MG, Goltz SR, Campbell WW. 2014. Unsaturated fatty acids promote bioaccessibility and basolateral secretion of carotenoids and α-tocopherol by Caco-2 cells. Food Funct. 5:1101–12.

Liu M-J, Bao S, Bolin ER, Burris DL, Xu X, Sun Q, Killilea DW, Shen Q, Ziouzenkova O, Belury MA, Failla ML, Knoell DL. 2013. Zinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet. J Nutr. 143(7):1036–45.

Victoria-Campos CI, Ornelas-Paz J de J, Yahia EM, Failla ML. 2013. Effect of the interaction of heat-processing style and fat type on the micellarization of lipid-soluble pigments from green and red pungent peppers (Capsicum annuum). J Agric Food Chem. 61(15):3642–53.

Yee LD, Agarwal D, Rosol TJ, Lehman A, Tian M, Hatton J, Heestand J, Belury MA, Clinton SK. 2012. The inhibition of early stages of HER-2/neu-mediated mammary carcinogenesis by dietary n-3 PUFAs. Mol Nutr Food Res. 57(2):320-327.

Tian M, Kliewer KL, Asp ML, Stout MB, Belury MA. 2011. C9t11-conjugated linoleic acid-rich oil fails to attenuate wasting in colon-26 tumor-induced late-stage cancer cachexia in male CD2F1 mice. Mol Nutr Food Res. 55(2):268-277.

Stout MB, Liu LF, Belury MA. 2011. Hepatic steatosis by dietary-conjugated linoleic acid is accompanied by accumulation of diacylglycerol and increased membrane-associated protein kinase C epsilon in mice. Mol Nutr Food Res. 55(7):1010-1017.

Ing SW, Belury MA. 2011. Impact of conjugated linoleic acid on bone physiology: Proposed mechanism involving inhibition of adipogenesis. Nutr Rev. 69(3):123-131.

Asp ML, Collene AL, Norris LE, Cole RM, Stout MB, Tang SY, Hsu JC, Belury MA. 2011. Time-dependent effects of safflower oil to improve glycemia, inflammation and blood lipids in obese, post-menopausal women with type 2 diabetes: A randomized, double-masked, crossover study. Clin Nutr. 30(4):443-449.

Yee LD, Lester JL, Cole RM, Richardson JR, Hsu JC, Li Y, Lehman A, Belury MA, Clinton SK. 2010. Omega-3 Fatty acid supplements in women at high risk of breast cancer have dose-dependent effects on breast adipose tissue fatty acid composition. Amer J Clin Nutr. 91(5):1185-1194.

McDaniel JC, Ahijevych K, Belury M. 2010. Effect of n-3 oral supplements on the n-6/n-3 ratio in young adults. West J Nurs Res. 32(1):64-80.

Norris LE, Collene AL, Asp ML, Hsu JC, Liu L-F, Richardson JR, Li D, Bell D, Osei K, Jackson RD, Belury MA. 2009. Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus. Am. J. Clin. Nutr. 90(3):468-476.

Garelnabi M, Selvarajan K, Litvinov D, Santanam N, Parthasarathy S. Dietary oxidized linoleic acid lowers triglycerides via APOA5/APOClll dependent mechanisms. Atherosclerosis 2008 Aug;199(2):304-9.

Brophy LT, Litvinov D, Parthasarathy S. Potential modulation of cholesterol homeostasis by sesamol [Abstract]. In: Arteriosclerosis Thromb Vasc Bio; Jun; Atlanta, GA. Philadelphia, PA: Lippincott Williams and Wilkins; 2008. p. E127.

Brophy LT, Selvarajan K, Jaichander P, Parthasarathy S. Atheroprotective role of sesamol: Modulation of the lipid profile [Abstract]. In: Arteriosclerosis Thromb Vasc Bio; Jun; Atlanta, GA. Philadelphia, PA: Lippincott Williams and Wilkins; 2008. p. E59.

Litvinov D, Garelnabi MO, Parthasarathy S. Lipid peroxide decomposition product azelaic acid may promote calcification in atherosclerosis [Abstract]. In: Arteriosclerosis Thromb Vasc Bio; Jun; Atlanta, GA. Philadelphia, PA: Lippincott Williams and Wilkins; 2008. p. E84.

McDaniel JC, Belury M, Ahijevych K, Blakely W. Omega-3 fatty acids effect on wound healing. Wound Repair Regen 2008 May;16(3):337-45.

Kent KD, Clubbs EA, Harper WJ, Bomser JA. Apoptotic effects of dietary and synthetic sphingolipids in androgen-independent (PC-3) prostate cancer cells. Lipids 2008 Feb;43(2):143-9.

Sun QH, Chang T, Kampfrath T, Lumeng CN, Yue PB, Vedamoorthy S, Desikan R, Parthasarathy S, Khan B, Rajagopalan S. Lipoic acid prevents insulin resistance and adipocyte inflammation [Abstract]. In: J Amer Coll Cardiology Mar; New York: Elsevier Science Inc; 2008. p. A294.

Wendel AA, Purushotham A, Liu LF, Belury MA. Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice. J Lipid Res 2008 Jan;49(1):98-106.

Garelnalbi MO, Selvarajan K, Litvinov D, Santanam N, Parthasarathy S. Dietary supplementation of oxidized linoleic acid lowers triglycerides in mice through APOC3/APOA5 dependent mechanism [Abstract]. In: Free Rad Biol Med; Nov; New York, NY: Elsevier Science Inc; 2007. p. S108-9.

Purushotham A, Shrode GE, Wendel AA, Liu LF, Belury MA. Conjugated linoleic acid does not reduce body fat but decreases hepatic steatosis in adult Wistar rats. J Nutr Biochem 2007 Oct;18(10):676-84.

Koba K, Belury MA, Sugano M. Potential health benefits of conjugated trienoic acids. Lipid Technology 2007 Sep;19(9):200-3.

Driskell J, editor. Sports Nutrition: Fats and Proteins. Boca Raton, FL: CRC Press; 2007. Ch 5. Koster CG, Belury MA. Conjugated linoleic acid as an ergogenic aid.

Garelnalbi MO, Jaichander P, Khan-Merchant N, Parthasarathy S. Diet enriched with oxidized fatty acids lowers triglyceride levels in mice [Abstract]. In: Arteriosclerosis Thromb Vasc Bio; Philadelphia, PA: Lippincott Williams & Wilkins; 2007. p. E91.

Kiecolt-Glaser JK, Belury MA, Porter K, Beversdorf DQ, Lemeshow S, Glaser R. Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults. Psychosom Med 2007 Mar;69(3):217-24.

Liu LF, Purushotham A, Wendel AA, Belury MA. Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity and hepatic steatosis in high fat fed mice. Am J Physiol Gastrointest Liver Physiol 2007 Feb;292(6):1671-82.

Purushotham A, Wendel AA, Liu LF, Belury MA. Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice. J Lipid Res 2007 Feb;48(2):444-52.

Belury MA, Kavanaugh CJ, Liu KL. Conjugated linoleic acid modulates phorbol ester-induced PPARdelta and K-FABP mRNA expression in mouse skin. Nutr Res 2007;27(1):48-55.

Huang Y, Yanagita T, Knapp H, editors. Dietary Fats and Risk of Chronic Disease. Urbana, IL: The American Oil Chemists’ Society; 2006. Belury MA, Asp ML, Collene AL, et al. Is there a role for conjugated linoleic acid to aid in the prevention of type 2 diabetes?

Liu LF, Purushotham A, Wendel AA, Belury MA. Dietary conjugated linoleic acid suppresses weight gain but increases hepatic micro-steatosis in mice [Abstract]. In: Hepatology; Oct; Hoboken, NJ: John Wiley & Sons Inc.; 2006. p. 671A.

Purushotham A, Liu LF, Wendel AA, Belury MA. Adiponectin attenuates hepatic steatosis and insulin resistance induced by dietary conjugated linoleic acid in mice [Abstract]. In: Hepatology; Oct; Hoboken, NJ: John Wiley & Sons Inc.; 2006. p. 671A.

Parada-Rabell F, Eastridge ML, Kuo CJ, Alvarez V, Todd A, Ribeiro CVDM, Engel J. Effects dietary supplementation of unsaturated fat, vitamin E, and sorbitol on fatty acid concentrations in milk and the properties of Cheddar cheese [Abstract]. In: J Animal Sci Jul; Savoy, IL: Amer Soc Animal Science; 2006. p. 317.

Liu LF, Purushotham A, Belury MA. Activation of peroxisome proliferator-activated receptor (PPAR) alpha by conjugated linoleic acid is modulated by Protein kinase C epsilon [Abstract]. In: FASEB J; Mar; Bethesda, MD: Federation Amer Soc Exp Biol; 2006. p. A1000-1.

Liu LF, Wendel AA, Belury MA. Effect of conjugated linoleic acid supplementation on rosiglitazone treatment in Ob/Ob mice [Abstract]. In: FASEB J; Mar; Bethesda, MD: Federation Amer Soc Exp Biol; 2006. p. A550-1.

Purushotham A, Shrode GE, Wendel AA, Belury MA. Dietary conjugated linoleic acid (CLA) attenuates hepatic steatosis by modifying stearoyl-CoA desaturase (SCD-1) mRNA and activity in high-fat-fed rats [Abstract]. In: FASEB J; Mar; Bethesda, MD: Federation Amer Soc Exp Biol; 2006. p. A574.

Weber TE, Richert BT, Belury MA, Gu Y, Enright K, Schinckel AP. Evaluation of the effects of dietary fat, conjugated linoleic acid, and ractopamine on growth performance, pork quality, and fatty acid profiles in genetically lean gilts. J Anim Sci 2006 Mar;84(3):720-32.

Wendel AA, Belury MA. Effects of conjugated linoleic acid and troglitazone on lipid accumulation and composition in lean and Zucker diabetic fatty (fa/fa) rats. Lipids 2006 Mar;41(3):241-7.

Wendel AA, Purushotham A, Belury MA. Leptin prevents insulin resistance induced by conjugated linoleic acid in obese mice [Abstract]. In: FASEB J; Mar; Bethesda, MD: Federation Amer Soc Exp Biol; 2006. p. A574.