Publications

Pre-print

  • K. Soares, C.J.B. de Oliveira, L.E. Villegas, P.C. Vasconcelos, A.E. Rodrigues, C. Madden, V.L. Hale. Are you my mother?: When host genetics and gut microbiota tell different phylogenetic stories in the Africanized honey bee hybrid (Apis mellifera scutellata x sspp.). Link.
  • Z.J. Lewis, A. Scott, C. Madden , E. Vik, A.A. Zayed, G.J. Smith, S. Justice, A. Rudinsky, J. Hokamp, V.L. Hale. Evaluating urine volume and host depletion methods to enable genome-resolved metagenomics of the urobiome. Link.
  • K. Soares, D. Ricke, C. de Oliveira, M. Lima, R. Mrofchak, A. Rodrigues, C. Madden, R. Johnson, V.L. Hale. Zinc and laboratory emerge date impact honey bee gut microbiota and survival. Link.

2023

  • K.O. Soares, V.L. Hale, G.R. de Medeiros, N.M.V. da Silva, M.V. Lima, T.F. da Rocha, P.B. Maracaja, J.H.S. Costa, A.E. Rodrigues, C.J.B de Oliveira. The honey bee gut microbiota: A review under the perspective of bees threatened by agrochemicals. Revista Observatorio de la Economia Latino Americana. (Latin American Economy Observations Journal). Link. PDF.
  • T.H.C. Wilde, R.K. Shukla, C. Madden, Y. Vodovotz, A. Sharma, W.S. McGraw, V.L. Hale. Simian Immunodeficiency Virus and Storage Buffer: Field-friendly preservation methods for RNA viral detection in primate feces. mSphere. Link.
  • R. Moore, V.L. Hale, J.A. Winston, T. Hare. Harnessing the microbiome to improve the health and well-being of animals and people. AVMA Journal. Link. PDF.
  • M. Ehrlich, C. Madden, D.S. McBride, J.M. Nolting, D. Huey, S. Kenney, Q. Wang, L. Saif, A. Vlasova, P. Dennis, D. Lombardi, S. Gibson, A. McLaine, S. Lauterbach, P. Yaxley, J. Winston, D. Diaz-Campos, R. Pesapane, M. Flint, J. Flint, R. Junge, S.A. Faith, A.S. Bowman, V.L. Hale. Lack of SARS-CoV-2 viral RNA detection among a convenience sampling of Ohio wildlife, companion, and agricultural animals, 2020-2021. Animals. Link. PDF.
  • A. McGlynn, R. Mrofchak, R. Madan, C. Madden, M.J. Jahid, D. Mollenkopf, T.E. Wittum, S. Justice, A. Rudinsky, J. Hokamp, V.L. Hale.  Longitudinal examination of urine pH, specific gravity, proteins, culture, and resistance profiles in healthy dogs. Journal of Veterinary Internal Medicine. 1-11. Link. PDF.
  • P.A. Boley, P.M. Dennis, J.N. Faraone, J. Xu, M. Liu, X. Niu, S.G. Gibson, V.L. Hale, Q. Wang, S. Liu, L.J. Saif, S.J. Kenney. SARS-CoV-2 Serological Investigation of White-Tailed Deer in Northeastern Ohio. Viruses. Link. PDF.

2022

  • R. Mrofchak, C. Madden, M.V. Evans, W.C. Kisseberth, D. Dhawan, D.K. Knapp, V.L. Hale. Urine and fecal microbiota in a canine model of bladder cancer and comparison of canine and human urine microbiota. All Life. Link.
  • D. Minich, C.Madden, M.A. Navarro, L. Glowacki, K. French-Kim, W. Chan, M.V. Evans, K. Soares, R. Mrofchak, R. Madan, G.A. Ballash, K. LaPerle, S. Paul, Y. Vodovotz, F.A. Uzal, M. Martinez, J. Hausmann, R.E. Junge, V.L. Hale. Gut microbiota and age shape susceptibility to clostridial enteritis in lorikeets under human care. Animal Microbiome. Link. PDF
  • V.L. Hale, P.M. Dennis, D.S. McBride, J.M. Nolting, C. Madden, D. Huey, M. Ehrlich, J. Grieser, J.A. Winston, D. Lombardi, S. Gibson, L. Saif, M.L. Killian, K. Lantz, R.M. Tell, M.K. Torchetti, S. Robbe-Austerman, M.I. Nelson, S.A. Faith, A. Bowman. SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus). Nature. Link. PDF.
  • S.K. Murray, C.M. Kurkul, A.J. Mularo, V.L. Hale, R.M. Adams, R.M. Johnson. Antibacterial effects of propolis and brood comb extracts on the causative agent of European Foulbrood (Melissococcus plutonius) in honey bees (Apis mellifera). Journal of Apicultural Research. Link. PDF.
  • K. Bernard, A. Davis, I.M. Simpson, V.L. Hale, J. Lee, R.J. Winston. Detection of SARS-CoV-2 in urban stormwater: An environmental reservoir and potential interface between human and animal sources. Science of the Total Environment. Link. PDF.
  • Book chapter: K.R. Amato, J.B. Clayton, V.L. Hale. The colobine gut microbiota: New perspectives on the nutrition and health of a specialized subfamily of primates. The Colobines: Natural History, Behaviour and Ecological Diversity. Eds. I. Matsuda, C.C. Grueter, J.A. Teichroeb. Cambridge University Press. Link.

2021

  • K. Soares, C.J. Bruno de Oliveira, A.E. Rodrigues, P.C. Vasconcelos, N.M. Vieira da Silva, O.G.C. Filho, C. Madden, V.L. Hale. Tetracycline exposure alters key gut microbiota in Africanized honey bees (Apis mellifera scutellata x spp). Frontiers in Ecology and Evolution. Special Issue: Impact of Anthropogenic Environmental Changes on Animal Microbiomes. Link. PDF.
  • A.G. Arruda, L. Deblais, V. Hale, C. Madden, M. Pairis-Garcia, V. Srivastava, D. Kathayat, A. Kumar, G. Rajashekara. Nasal and gut microbiota for sows of different health status within six commercial swine farms from one swine production system. PeerJ. 9:e12120. Link. PDF.
  • R. Mrofchak, C. Madden, M.V. Evans, V.L. Hale. Evaluating extraction methods to study canine urine microbiota. PLOS One. Link. PDF.
  • D. Minich, C. Madden, M.V. Evans, G.A. Ballash, D.J. Barr, K.P. Poulsen, P.M. Dennis, V.L. Hale. Alterations in gut microbiota linked to provenance, sex, and chronic wasting disease in white-tailed deer (Odocoileus virginianus). Scientific Reports. Link. PDF.
  • V.L. Hale. mSphere of Influence: Drivers of Host-Associated Microbial Community Structure and Change. mSphere. 6:e00248-21. Link. PDF.

2020

  • A.M. Antonson, M.V. Evans, J.D. Galley, H.J. Chen, T.A. Rajasekera, S.M. Lammers, V.L. Hale, M.T. Bailey, T.L. Gur. Unique maternal immune and functional microbial profiles during prenatal stress. Scientific Reports. Link. PDF.
  • M. Kim, E. Vogtmann, D.A. Ahlquist, M.E. Devens, J.B. Kisiel, W.R. Taylor, B.A. White, V.L. Hale, J. Sung, N. Chia, R. Sinha, J. Chen. Fecal metabolomic signatures in colorectal adenoma patients are associated with gut microbiota and early events of colorectal cancer pathogenesis. mBio. 11:1. Link. PDF.

2019

  • J.C. Yu, V.L. Hale, H. Khodadadi, B. Baban. 2019. Whole body vibration-induced omental macrophage polarization and fecal microbiome modification in a murine model. International Journal of Molecular Sciences. 20: 3125. Link. PDF.
  • V.L. Hale, C.L. Tan, K. Niu, Y. Yang, Q. Zhang, R. Knight, K.R. Amato. 2019. Gut microbiota in wild and captive Guizhou snub-nosed monkeys, Rhinopithecus brelichi. American Journal of Primatology. 8:e22989. Link. PDF
  • G.B. Saffouri, R. Shields-Cutler, J. Chen, Y. Yang, H.R. Lekatz, V.L. Hale, J.M. Cho, E.J. Battaglioli, Y. Bhattarai, K.J. Thompson, K.K. Kalari, G. Behera, J.C. Berry, S.A. Peters, R. Patel, A.N. Schuetz, J.J. Faith, M. Camilleri, J.L. Sonnenburg, G. Farrugia, J.R. Swann, M. Grover, D. Knights, P.C. Kashyap. 2019. Small intestinal microbial composition is more relevant than quantitative small intestinal culture in patients with gastrointestinal symptoms. Nature Communications: 10: 2012.  Link. PDF.
  • G.M. Sindberg, S.E. Callen, S. Banerjee, J. Meng, V.L. Hale, R. Hegde, P.D. Cheney, S. Buch, S. Roy. 2019. Morphine potentiates dysbiotic microbial and metabolic shifts in SIV infection. Journal of Neuroimmune Pharmacology. 14:200-2014. Link. PDF.

2018

  • V.L. Hale*, P. Jeraldo*, J. Chen, M. Mundy, J. Yao, S. Priya, G. Keeney, K. Lyke, J. Ridlon, B.A. White, A.J. French, S. Thibodeau, C. Diener, O. Resendis-Antonio, J. Gransee, T. Dutta, X.M. Petterson, R. Blekhman, L. Boardman, D. Larson, H. Nelson, N. Chia. Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers. Genome Medicine. 10:78. *co-first author. Link. PDF.
  • E.J. Battaglioli*, V.L. Hale*, J. Chen, P. Jeraldo, C. Ruiz Mojica, B.A. Schmidt, V.M. Rekdal, L.M. Till, L. Huq, S.A. Smits, W.J. Moor, Y. Jones-Hall, T. Smyrk, S. Khanna, D.S. Pardi, M. Grover, R. Patel, N. Chia, H. Nelson, J.L. Sonnenburg, G. Farrugia, P.C. Kashyap. Clostridioides difficile uses amino acids associated with gut microbial dysbiosis in a subset of patients with diarrhea. Science Translational Medicine.  10:eaam7019. *co-first author Link. PDF. Video.
  • J.C. Yu, H. Khodadadi, A. Malik, B. Davidson, E. dS.L. Salles, J. Bhatia, V.L. Hale, B. Baban. Innate Immunity of Neonates and Infants: The status of Innate Lymphoid Cells. Frontiers in Immunology. 9:1759. Link. PDF.
  • V.L. Hale, P. Jeraldo, M. Mundy, J. Yao, G. Keeney, N. Scott, H. Cheek, J. Davidson, M. Green, C. Martinez, J. Lehman, C. Pettry, E. Reed, K. Lyke, B.A. White, C. Diener, O. Resendis-Antonio, J. Gransee, T. Dutta, X.M. Persson, L.A. Boardman, D. Larson, H. Nelson, N. Chia. Synthesis of multi-omic data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer. Methods. 149:59-68. Link. PDF.
  • V.L. Hale, C.L. Tan, K. Niu, Y. Yang, R. Knight, Q. Zhang, D. Cui, K.R. Amato. Diet vs. Phylogeny: A comparison of gut microbiota in captive colobine monkey species.  Microbial Ecology. 75:515-527. Link. PDF.
  • J.M. Allen, L.J. Mailing, J. Cohrs, C. Salmonson, J. Fryer, N. Vandana, MD, V.L. Hale, P. Kashyap, B. White, J.A. Woods. Exercise training-induced modifications of the gut microbiota can mediate host response to microbial colonization and colitis insult in gnotobiotic mice. Gut Microbes. 9:115-130. Link. PDF.

2017

  • L.R. Thompson, J.G. Sanders, D. McDonald et al. & the Earth Microbiome Project Consortium (300+ authors including V.L. Hale). A communal catalogue reveals Earth’s multiscale microbial diversity. Nature. 551: 457-463. Link. PDF.
  • V.L. Hale, S. Thompson, L. Corriveau, B. MacGowan, D. Huse. Radio transmitter application in the wild timber rattlesnake, Crotalus Horridus. Journal of Wildlife Diseases. 53: 591-595. Link. PDF.

2016

  • V.L. Hale,*, J. Chen*, S. Johnson, T.C. Yab, S. Harrington, T.C. Smyrk, H. Nelson, L.A. Boardman, B.R. Druliner, T.R. Levin, D.K. Rex, D.J. Ahnen, P. Lance, D.A. Ahlquist, N. Chia. Shifts in the fecal microbiota associated with adenomatous polyps suggest a link between diet, gut microbes, and colorectal cancer. Cancer Epidemiology Biomarkers & Prevention. 26: OF1-OF10. *co-first author. Link. PDF.
  • Sung*, V. Hale*, A.C. Merkel, P.J. Kim, N. Chia. 2016. Metabolic modeling with Big Data and the gut microbiome. Applied & Translational Genomics. 10:10-15.*co-first author Link. PDF.
  • K.R. Amato, J.L. Metcalf, S.J. Song, V.L. Hale, J. Clayton, G. Ackermann, G. Humphrey, C. Tan, R. Knight, J. Braun. Using the gut microbiota as a novel tool for examining colobine primate GI health. Global Ecology and Conservation. 7: 225-237. Link. PDF.
  • V.L. Hale, C.L. Tan, K. Niu, Y. Yang, D. Cui, H. Zhao, R. Knight. K.R. Amato. Effects of field conditions on fecal microbiota. Journal of Microbiological Methods. 10: 180-188. Link. PDF.

2015

  • V.L. Hale, C.L. Tan, K.R. Amato. 2015. Effect of preservation method on spider monkey (Ateles geoffroyi) fecal microbiota over 8 weeks. Journal of Microbiological Methods. 13:16-26. Link. PDF.