Bioinformatics and Mathematical Biosciences Lab


RESEARCH TOPICS     

Single-cell RNA-Seq data modeling & analyses:

  • Inference of heterogenous regulatory mechanisms across various cell types
  • Development of integrated single-cell RNA-Seq data analysis tools

Regulatory DNA motif researches:

  • Discovery and computational analyses of cis-regulatory motifs
  • Prediction of metabolic networks and associated regulatory networks

Gene expression modeling & analyses:

  • Comparative and functional genomics analysis
  • Biclustering of large-scale (temporal/spatial) gene expression data 

Microbial system biology

  • Elucidation and application of organizing principles of bacterial genomes
  • Metagenomics and metatranscriptomics data analysis in microbes
  • Computational analysis and modeling of human-microbiome interaction