Grants

NIH-NIGMS (R01), PI

  • Title: Construction of cell-specific gene co-regulation signatures based on single-cell transcriptomics analysis. (R01GM131399-01)
    • 2018 – 2022
  • Supplementary:  Administrative Supplements Equipment (R01GM131399-03S1).
    • One-time device purchase (2020)

NIH-NCI (U24), MPI (PI: John Bridges)

  • Title: Participant Engagement and Cancer Genome Sequencing: Coordinating Center.
    • 2020-2025

NIH (R01), co-I (PI: Dana McTigue)

  • Title: Identify mechanisms driving neurogenic NASH.
    • 2021-2026

NIH (R01), co-I (PI: Jason Wester)

  • Title: Development of neuronal subtypes and local circuits in the hippocampus.
    • 2021-2026

NIH (R01), co-I (PI: Haitao Wen)

  • Title: Targeting immune inhibitory molecule SUSD2 to reverse immunosuppression.
    • 2021-2026

NIH (R01), co-I (PI: Xuefeng Liu)

  • Title: Conditionally reprogrammed cell model for castration-resistant prostate cancer.
    • 2019-2023

NIH (R01), co-I (PI: Zihai Li)

  • Title: Targeting GRP94-TGF-beta pathway for cancer immunotherapy.
    • 2021-2026

NIH (R25), co-I (PI: Rusty Gunser)

  • Title: Training informaticians in big data (TIBD) (R25MD011712).
    • 2017-2021

NIH (R01), co-I (PI: Yutong Zhao)

  • Title: Regulation of proteolysis by deubiquiting enzyme in lung inflammatory disease (R01HL131665).
    • 2019-2021

NSF (IIBR), PI

  • Title: A reinforced imputation framework for accurate gene expression recovery from single-cell RNA-seq data (NSF1945971).
    • 2021-2023

NSF (IOS), co-I (PI: Allison  Miller)

  • Title: Adapting perennial crops for climate change: Graft transmissible effects of rootstocks on grapevine shoots (NSF1546869).
    • 2016 – 2022

BMI pilot, PI

  • Title: Identifying master transcription factors in adaptive immune systems using single-cell RNA/ATAC-seq data.
    • 05/01/2021 – 04/30/2022

BMI pilot, MPI (PI: Dongjun Chung)

  • Title: A Computational Framework for Integrative Analysis of Single Cell TCR-seq and RNA-seq Data for the Immuno-Oncology Investigation of Sex Differences.
    • 05/01/2021 – 04/30/2022

BrightFocus Foundation, co-I (PI: Hongjun Fu)

  • Title: Cerebral organoids to investigate cellular and neuronal network vulnerable in Alzheimer’s Disease and progressive supranuclear palsy.
    • 2021-2024

OSUCCC (PIIO), co-I (PI: Haitao Wen)

  • Title: Targeting immune inhibitory molecule SUSD2 to rejuvenate CD8+ T cell antitumor immunity.
    • 2021-2023

(Completed) Center for Clinical and Translational Science – Pilot, PI

  • Title: A computational pipeline for functional profiling of human gut microbiome and their associations with human chronic diseases.
    • 09/1/2019 – 08/31/2020

(Completed) Center for Clinical and Translational Science – Pilot (Artificial Intelligence and Machine Learning in Translational Science and Human Health), PI

  • Title: Deep Transfer Learning of Drug Sensitivity by Integrating Bulk and Single-cell RNA-Seq data.
    • 09/1/2020 – 08/31/2021

(Completed) Center for Clinical and Translational Science – Pilot (Foods for Health Seed Grant), co-I

  • Title: Food Products for the Targeted Enrichment of Gut Microbes.
    • 09/01/2019 – 08/31/2020