Seminars – Oct 22th 5pm – “Science is Too Important to be Left Just to Men”

There will be a special seminar next week by Dr. Debra Rolison from the Naval Research Laboratory.

Title: “Science is Too Important to be Left Just to Men”
Place: E0040
Date: Oct 22, 2019
Time: 5 – 6 pm

Since it coincides with our October meeting, MSDG is canceled for this month.

This seminar will be beneficial for grad students/postdocs and we encourage them to attend.

Dr. Rolison will give research presentation earlier in the day.

Title: “Scalable Multifunctional Nanoarchitectures for Energy Storage”

Oct 22, 11:30 AM, 100 Stillman

Bio: https://en.wikipedia.org/wiki/Debra_R._Rolison

Meeting – Sept 24th @ 5:30PM

Topic: Thermal ionization mass spectrometry methods and applications in the earth and ocean sciences

Overview by Prof. Elizabeth Griffith, School of Earth Sciences, OSU

Application by Ms. Samantha Carter, Griffith Research Group, OSU

Date: September 24
Time: 5:30 PM
Place: JAMES B050 (460 W. 10TH Ave)

Don’t miss OMSMS 2019!

Please join us for the 3rd Annual Ohio Mass Spectrometry and Metabolomics Symposium (OMSMS) to be held at the Blackwell Inn and Pfahl Conference Center at The Ohio State University in Columbus, Ohio, on October 1-2, 2019.

  • Invited keynote and plenary presentations:
    • Connecting the World’s Mass Spectrometry Data to Understand the Chemistry of Life — a Big Data Strategy, Pieter Dorrestein, UCSD
    • Mass Spectrometry Imaging Applications to Support Clinical Decision Making, Nathalie Agar, Harvard Medical School
    • Harnessing Metabolomics to Combat Infectious Diseases, Ian Lewis, University of Calgary
    • The Exposome Meets Precision Nutrition, Susan Sumner, UNC
  • Introductory workshops in Metabolomics and Native Mass Spectrometry
  • Oral, poster and flash talk presentations (submitted abstracts)
  • Evening reception
  • Lunch and Learn sessions
  • Networking opportunities

REGISTER TODAY! Registration closes September 17

The purpose of the two-day joint meeting of the 16th Annual Ohio Mass Spectrometry Symposium and 3rd Annual Conference on Food and Nutritional Metabolomics is to provide an opportunity for academic and industrial researchers in the region to present their findings, share information, discuss research challenges with colleagues, and spark new collaborations in the rapidly advancing fields of mass spectrometry and metabolomics. Key topics will include Advanced Ionization Techniques and Instrumentation, Structural Biology, and Personalized Nutrition.

The symposium is planned and co-hosted by the OSU Campus Chemical Instrument Center, National Resource for Native MS-Guided Structural Biology, and the OSU Foods for Health program.

OMSMS is made possible with generous sponsorships from Center for Applied Plant Sciences (CAPS), Metabolon, Abbott, Agilent, Bruker, SCIEX, Waters, Thermo Fisher Scientific, 908 Devices, Advion, and Biocrates.

Visit go.osu.edu/omsms for additional symposium information and links to registration.

Meeting – August 27th @ 5:30PM

Mr. Taghi Sahraeian, Badu Research Group, OSU
“Droplet Imbibition Enables Non-Equilibrium Interfacial Reactions in Charged Microdroplets”

Date: August 27th
Time: 5:30 PM
Place: 105 BRT

COH-MSDG – Central Ohio (OH) Mass Spectrometry Discussion Group

Seminar – August 20th 4:00PM – “Deciphering Proteins with Unknown Functions in Plants using Top-Down and Native Mass Spectrometry Techniques”

Mowei Zhou will present a seminar while visiting us from Pacific Northwest National Laboratory next week:

“Deciphering Proteins with Unknown Functions in Plants using Top-Down and Native Mass Spectrometry Techniques”

Tuesday, August 20
4:00 pm
BRT 105

Mass spectrometry (MS) has been widely used in proteomics applications for identifying and quantifying proteins in biological samples, particularly in the field of biomedical research. In recent years, many new MS techniques, including top-down MS, and native MS for comprehensive characterization of post-translational modification (PTM), ligand/metal binding, higher-order structures, and protein-protein interactions. At the Environmental Molecular Sciences Laboratory (EMSL), a Department of Energy (DOE) user facility located at the Pacific Northwest National Laboratory (PNNL), we aim to use advanced analytical tools to build up a mechanistic understanding of biological processes that affect the environment, and to harness enzymes that can produce sustainable “green” fuels from biomass. Despite the fast-expanding knowledge of plant and microbial organisms from genomics and transcriptomics research, many of the genes still have unknown functions and remain to be characterized at the protein level. I will highlight a few recent EMSL projects applying top-down and native MS to uncharacterized proteins. The focus will be on histone modifications in epigenetic control of drought stress in sorghum crop; a plant enzyme heterocomplex in vitamin B6 biosynthesis with tunable stoichiometry; and an unknown plant enzyme complex controlling lignin synthesis.

Seminar – June 25th 10:00-11:00am “Uncovering Antimicrobial Peptide Interactions in Lipid Nanodiscs by Native MS”

A special seminar will be presented by Dr. Michael T. Marty (University of Arizona) on
Uncovering Antimicrobial Peptide Interactions in Lipid Nanodiscs by Native MS.

Tuesday, June 25th
10:00-11:00 am
BRT 105

Research in the Marty lab is focused on developing mass spectrometry methods to study the structure and biophysics of membrane proteins. Working at the interface of Analytical Chemistry and Biochemistry, they utilize lipoprotein Nanodiscs to solubilize membrane proteins in a lipid bilayer with a defined composition. Dr. Marty is at the forefront of development of new computational approaches and software for analysis of native MS data. This work builds on UniDec software developed to rapidly and robustly deconvolve mass and ion mobility spectra.

The seminar is supported by the Resource for Native MS-Guided Structural Biology.

Seminiar – May 22 1:30-2:30pm “The importance of isotopic fine structures in ultrahigh resolution FT-ICR analyses”

We will have an off-semester seminar presented by Prof. Eugene Nikolaev (Skoltech Institute of Science and Technology, Moscow, Russia) on
“The importance of isotopic fine structures in ultrahigh resolution FT-ICR analyses”.

Prof. Nikolaev is a well-known and prominent scientist who has made significant contribution to Fourier-transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry analyses and instrument design. We allocated some extra time for discussion after his seminar.
I hope to see you many of you at Prof. Nikolaev’s seminar.

Time: May 22nd (Wed) 1:30-2:30 pm
Location: DHLRI 165

Meeting – April 23rd @ 5:30pm

1. Mr. Ben Burris, Badu Research Group, OSU
“Probing Kinetics of Biomolecular Reactions via Contained-ESI Mass Spectrometry”

2. Ms. Maddy Lomax-Vogt, Olesik Research Group, OSU
“Inductively Coupled Plasma Fundamentals and Nanoparticle Measurements”

Date: April 23
Time: 5:30 PM
Place: 2015 MP

Meeting – March 25th @ 5:30pm

Prof. Jenny Brodbelt, Department of Chemistry, The University of Texas at Austin
“Lipid analysis using UVPD”

Date: March 25
Time: 5:30 PM
Place: BRT 115

Meeting – February 26th @ 5:30PM

1. Prof. Chris Zhu, Human Sciences, OSU
“Studies of gut bacterial metabolites using MS-based metabolomics and an in vitro human colonic model (HCM)”

2. Dr. Djawed Bennouna, Kopec Research Group, OSU
“The Study of the impact of environment and genetics on the nutritional quality of rapeseed by a metabolomic approach”

Date: February 26
Time: 5:30 PM
Place: 2015 MP (053, 140 W 18th Ave)

Meeting – January 22nd @ 5:30pm

Ms. Devin Swiner, Badu Research Group, Ohio State
“Microsampling with Cotton Threads”

Dr. Dalton Snyder, CCIC, Ohio State
“Neutral loss MS/MS scans in a linear quadrupole ion trap and application to analysis of pharmaceutical mixtures via ion/molecule reactions”

Date: January 22nd
Time: 5:30PM
Location: TBA

Meeting – December 4th @ 5:30PM

Dr. Arpad Somogyi, CCIC, Ohio State
“Availability of a new ion mobility technique TIMS (trapped ion mobility spectrometry), in the CCIC Mass Spec and Proteomics Facility: implementation on a Q-TOF and an FT-ICR instrument ”

Prof. Abraham Badu-Tawiah, Badu Research Group, Ohio State
“New Approaches for Ultra-small Volume Analysis by Mass Spectrometry”

Date: December 4th
Time: 5:30PM
Location: TBA

Meeting – November 11th @ 5:30PM

Prof. Heather Desaire, University of Kansas, Lawrence
“Combining Machine Learning, Mass Spectrometry, and Glycomics to Diagnose Disease”

Date: November 11th
Time: 5:30PM
Location: TBA

Meeting – October 1st @ 5:30PM

Prof. Christian Bleiholder, Florida State University, Tallahassee
“Protein structure analysis with ion mobility spectrometry/mass spectrometry: what are the challenges?”

Date: October 1st
Date: 5:30PM
Location: TBA

Meeting – September 5th @ 5:30PM

Ms. Samantha Sarni, Wysocki Research Group, Ohio State
“Unlocking the Mechanism of HIV-1 Viral Assembly Initiation with Native Mass Spectrometry”

Date: September 5th
Time: 5:30PM
Location: TBA

Meeting – April 23rd @ 5:30PM

Prof. Lars Konnerman, The University of Western Ontario, London
“From Solution into the Gas Phase: A Look at Electrosprayed Protein Ions and ESI Mechanisms”

Date: April 23rd
Time: 5:30PM
Location: TBA

Meeting – March 29th @ 5:30PM

Prof. Laura Reed, University of Alabama, Tuscaloosa
“Disentangling the gene-by-environment interaction architecture of metabolic disease through the lens of evolutionary genetics and metabolomics”

Date: March 29th
Time: 5:30PM
Location: TBA

Meeting – February 20th @ 5:30PM

Mr. William Andrews, Hummon Research Group, Ohio State
“Enhancing Mass Spectrometric Molecular Imaging Through Active Analyte Extraction”

Ms. Sierra Jackson, Badu Research Group, Ohio State
“Thread Spray Mass Spectrometry for Direct Analysis of Capsaicinoids in Pepper Products”

Date: February 20th
Time: 5:30PM
Location: TBA

Meeting – January 23rd @ 5:30PM

Mrs. Bernice Agana, Wysocki Research Group, Ohio State
“Multi-omics Profiling of LKB1 Mutant NSCLC Cells to Characterize Deregulated Pathways Contributing to Tumorigenesis”

Mr. Dmytro Kulyk, Badu Research Group, Ohio State
“Multi-mode Nano-Contained Ion Source Capable of ESI and APCI”

Date: January 23rd
Time: 5:30PM
Location: TBA