Title: “Fishing out elusive species from chemical reactions”
Prof. Shibdas Banerjee will be giving a talk at CBC’s analytical/physical seminar series. Shibdas is currently an Assistant Professor at Indian Institute of Science Education and Research Tirupati. He recently completed his postdoctoral studies with Prof. Dick Zare at Stanford University.
Date: August 30th, 2021
Time: 4:10 PM EST
Prof. Peter Nemes, University of Maryland, “Single-cell Mass Spectrometry Discovers Metabolic Effectors of Cell Differentiation”
Date: November 2, 2020
Time: 4:10 PM EST
Place: Zoom – link provided via email or contact firstname.lastname@example.org
There will be a special seminar next week by Dr. Debra Rolison from the Naval Research Laboratory.
Title: “Science is Too Important to be Left Just to Men”
Date: Oct 22, 2019
Time: 5 – 6 pm
Since it coincides with our October meeting, MSDG is canceled for this month.
This seminar will be beneficial for grad students/postdocs and we encourage them to attend.
Dr. Rolison will give research presentation earlier in the day.
Title: “Scalable Multifunctional Nanoarchitectures for Energy Storage”
Oct 22, 11:30 AM, 100 Stillman
“Panoptic Mass Spectrometry: How and Why”
Date: Sept 16, 2019
Time: 4:10 PM
Place: 130 CBEC
Mowei Zhou will present a seminar while visiting us from Pacific Northwest National Laboratory next week:
“Deciphering Proteins with Unknown Functions in Plants using Top-Down and Native Mass Spectrometry Techniques”
Tuesday, August 20, 2019
Mass spectrometry (MS) has been widely used in proteomics applications for identifying and quantifying proteins in biological samples, particularly in the field of biomedical research. In recent years, many new MS techniques, including top-down MS, and native MS for comprehensive characterization of post-translational modification (PTM), ligand/metal binding, higher-order structures, and protein-protein interactions. At the Environmental Molecular Sciences Laboratory (EMSL), a Department of Energy (DOE) user facility located at the Pacific Northwest National Laboratory (PNNL), we aim to use advanced analytical tools to build up a mechanistic understanding of biological processes that affect the environment, and to harness enzymes that can produce sustainable “green” fuels from biomass. Despite the fast-expanding knowledge of plant and microbial organisms from genomics and transcriptomics research, many of the genes still have unknown functions and remain to be characterized at the protein level. I will highlight a few recent EMSL projects applying top-down and native MS to uncharacterized proteins. The focus will be on histone modifications in epigenetic control of drought stress in sorghum crop; a plant enzyme heterocomplex in vitamin B6 biosynthesis with tunable stoichiometry; and an unknown plant enzyme complex controlling lignin synthesis.
A special seminar will be presented by Dr. Michael T. Marty (University of Arizona) on
Uncovering Antimicrobial Peptide Interactions in Lipid Nanodiscs by Native MS.
Tuesday, June 25th
Research in the Marty lab is focused on developing mass spectrometry methods to study the structure and biophysics of membrane proteins. Working at the interface of Analytical Chemistry and Biochemistry, they utilize lipoprotein Nanodiscs to solubilize membrane proteins in a lipid bilayer with a defined composition. Dr. Marty is at the forefront of development of new computational approaches and software for analysis of native MS data. This work builds on UniDec software developed to rapidly and robustly deconvolve mass and ion mobility spectra.
The seminar is supported by the Resource for Native MS-Guided Structural Biology.
We will have an off-semester seminar presented by Prof. Eugene Nikolaev (Skoltech Institute of Science and Technology, Moscow, Russia) on
“The importance of isotopic fine structures in ultrahigh resolution FT-ICR analyses”.
Prof. Nikolaev is a well-known and prominent scientist who has made significant contribution to Fourier-transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry analyses and instrument design. We allocated some extra time for discussion after his seminar.
I hope to see you many of you at Prof. Nikolaev’s seminar.
Time: May 22nd (Wed) 1:30-2:30 pm
Location: DHLRI 165