2024
[Dec 30, 2024] Congratulations to Dr. Qin Ma (MPI) and Dr. Jordan Krull (co-I) for winning OSU CCC Transitional Therapeutics FY25 seed award (grant), titled “AI-Driven Predictive Biomarkers for Immune Checkpoint Inhibitor Therapy in Clear Cell Renal Cell Carcinoma”!
[Dec 6, 2024] Congratulations to Dr. Qin Ma for winning the 2024 BSGP Faculty Peer Mentor Award!
[Dec 6, 2024] We are happy to share that our PostDoc, Xiaoying Wang, has been selected for the 2024 BMI Award Winner for Postdoctoral Researcher. Congratulation!
[Nov 8, 2024] We are excited to share that our collaborative paper titled “scDOT: optimal transport for mapping senescent cells in spatial transcriptomics” has been officially published in Genome Biology!
[Oct 22, 2024] We are delighted to share that our collaborate paper titled “Applying single cell genomics to studies of cellular heterogeneity and cell fate transitions in the brain” has been accepted for publication in Nature Neuroscience!
[Oct 21, 2024] Our Biostatistics Analyst, Cankun Wang, has been selected to participate in the Quantum Computing: New Frontiers in Biomedical Research Innovation Lab, scheduled for December 2-6, 2024, at Skamania Lodge in Washington.
[Oct 18, 2024] Our Biostatistics Analyst, Cankun Wang, gave a talk named “ssREAD: a single-cell and spatial RNA-seq database for Alzheimer’s disease” in the International Conference on Intelligent Biology and Medicine (ICIBM 2024), Houston, TX on Oct 12, 2024.
[Oct 18, 2024] Professor Dr. Qin Ma gave a talk titled “Deep learning shapes single-cell data analysis” in the International Conference on Intelligent Biology and Medicine (ICIBM 2024), Houston, TX on Oct 11, 2024.
[Oct 18, 2024] Assistant Professor Dr. Anjun Ma gave a talk named “Learning Health Systems: applications in behavioral health” in the International Conference on Intelligent Biology and Medicine (ICIBM 2024), Houston, TX on Oct 11, 2024.
[Oct 18, 2024] Our PostDoc, Yuzhou Chang gave a talk titled “Graph signal processing in spatial omics” in the International Conference on Intelligent Biology and Medicine (ICIBM 2024), Houston, TX on Oct 11, 2024.
[Oct 18, 2024] Our PostDoc, Xiaoying Wang gave a talk titled “MarsGT: Multi-omics analysis for rare population inference using single-cell graph transformer” in the International Conference on Intelligent Biology and Medicine (ICIBM 2024), Houston, TX on Oct 11, 2024.
[Oct 18, 2024] Dr. Qin Ma was invited to give a presentation named “Graph representation learning of single-cell and spatial transcriptomics data” for CPH Seminar in Precision Medicine of UTHealth in Houston, TX on Oct 11, 2024.
[Oct 18, 2024] Dr. Qin Ma gave a talk titled “Deep learning shapes big Omics data in cancer research” at the 25th OSU James Cancer Center Annual Scientific Meeting on Oct 10, 2024.
[Sep 23, 2024] Our Biostatistics Analyst, Shaopeng Gu, gave a talk titled “DILI with Commonly Used Antibiotics in the All of Us Research Program” at the PGRN 2024 All of Us Research Workshop on Sep 23, 2024.
[Sep 16, 2024] We are delighted to share that our collaborate paper titled “Maternal Blood Cell-Free RNA Signatures in Fetus with Congenital Heart Disease” has been accepted for publication in Circulation Research as a Research Letter!
[Sep 6, 2024] Our PostDoc, Yuzhou Chang, will give a talk titled “Graph Fourier transform for spatial omics representation and analyses of complex organs” at the BIOTRAC Spatial Biology Symposium on Sep 9, 2024.
[Aug 22, 2024] We are excited to share that a collaborative project with Dr. Zihai Li has been awarded an NCI R01 grant titled “Targeting GARP-TGFb” for Immunotherapy of Non-Small Cell Lung Cancer”!
[Aug 19, 2024] We are thrilled to announce that Dr. Qin Ma has been awarded a grant from the National Institute of General Medical Sciences (NIGMS) as a MPI, grant number R01GM152585. The grant is titled “Statistical power analysis framework for multi-sample and cross-platform spatial omics experiments”!
[Aug 13, 2024] Our manuscript titled “An Explainable Graph Neural Framework to Identify Cancer-Associated Intratumoral Microbial Communities” has been accepted for publication in Advanced Science!
[Aug 8, 2024] We are delighted to share that our manuscript titled “Graph Fourier transform for spatial omics representation and analyses of complex organs” has been accepted for publication in Nature Communications!
[Aug 7, 2024] Our collaborative paper titled “Applications of artificial intelligence to myeloproliferative neoplasms: a narrative review” has been accepted for publication in Expert Review of Hematology!
[Aug 2, 2024] We are happy to announce that our Postdoc, Dr. Jordan Krull, has been selected to receive a Research in Emerging Areas Critical to Human Health LRP award from the NATIONAL CANCER INSTITUTE (NCI)!
[Jul 17, 2024] Our collaborative paper titled “The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors” has been accepted for publication in the Journal of Cancer Research Communications!
[Jul 14, 2024] The paper titled “Clinical and translational mode of single-cell measurements: An artificial intelligent single-cell” has been accepted for publication in Clinical and Translational Medicine!
[Jul 11, 2024] The paper titled “Enhancer-driven gene regulatory networks inference from single-cell RNA-seq and ATAC-seq data” has been accepted for publication in Briefings in Bioinformatics!
[Jul 5, 2024] Our collaborative paper titled “Analysis of community connectivity in spatial transcriptomics data” has been officially published in the Journal of Frontiers in Applied Mathematics and Statistics!
[Jun 26, 2024] Our collaborative paper titled “The tumor microbiome reacts to hypoxia and can influence response to radiation treatment in colorectal cancer” has been officially published in the Journal of Cancer Research Communications!
[Jun 11, 2024] The paper titled “Harnessing the deep learning power of foundation models in single-cell omics” has been accepted for publication in Nature Reviews Molecular Cell Biology.
[May 17, 2024] Our collaborative paper titled “Spatial and functional targeting of intratumoral Tregs reverses CD8+ T cell exhaustion and promotes cancer immunotherapy” has been officially accepted for publication in the Journal of Clinical Investigation!
[April 19, 2024] We are excited to highlight the presentation by Dr. Jordan Krull at 2024 Pelotonia Scholars Symposium on how Deep Learning is revolutionizing digital pathology. His insights on extracting crucial numerical features from pathology slides are reshaping medical diagnostics.
[March 24, 2024] Dr. Qin Ma presented “Graph Representation Learning of Single-Cell and Spatial Transcriptomics Data,” at the 20th Annual Meeting of the MidSouth Computational Biology and Bioinformatics Society (MCBIOS) held at the Rollins School of Public Health, Emory University.
[February 21, 2024] Congratulations on Dr. Anjun Ma, who has been awarded the PKD RRC Pilot and Feasibility Award, securing a grant of $63,500 for his project titled “Constructing a Cross-Species Single-cell Database in Polycystic Kidney Disease”.
[Feb-14-2024] Led by Jianying Li, the manuscript “Targeting metabolic sensing switch GPR84 on macrophages for cancer immunotherapy” has been officially published in Cancer Immunology, Immunotherapy.
[Feb-7-2024] Dr. Qin Ma has been featured in interview by the “The Multi-Omics Playbook”. This playbook is a comprehensive guide that delves into the integrated application of multi-omics approaches in our research. It covers essential methodologies, best practices, and insightful case studies that can enhance our understanding and application of multi-omics data.
[Jan-24-2024] The manuscript “MarsGT: Multi-omics analysis for rare population inference using single-cell graph transformer” was recently recognized among the top 50 Biotechnology and methods papers by Nature Communications.
[Jan-6-2024] Our collaborative paper titled “Human iPSC-based model of COPD to investigate disease mechanisms, predict SARS-COV-2 outcome, and test preventive immunotherapy,” has been officially published in Stem Cells!
[Jan-6-2024] Led by Dr. Xiaoying Wang, the paper titled “MarsGT: Multi-omics analysis for rare population inference using single-cell graph transformer” has been officially published in Nature Communications.
[Jan-4-2024] Our collaborative paper titled “mRNA vaccines against SARS-CoV-2 induce divergent antigen-specific T-cell responses in patients with lung cancer,” has been officially published in Journal for Immunotherapy of Cancer!
2023
[Dec-14-2023] Congratulations to Dr. Jordan Krull for securing 2nd place in the Postdoc/Resident/Fellows category at the PIIO Symposium Poster Session!
[Dec-12-2023] Our collaborative paper titled “Targeting Metabolic Sensing Switch GPR84 on Macrophages for Cancer Immunotherapy,” is accepted to be published in Cancer Immunology, Immunotherapy!
[Dec-12-2023] Congratulations to Yuzhou Chang on a successful defense and a smooth Ph.D. graduation journey!
[Dec-12-2023] Dr. Qin Ma was awarded Excellence in Faculty Teaching in the Department of Biomedical Informatics for the year 2023. Congratulations!
[Dec-12-2023] Dr. Qin Ma was awarded Excellence in Faculty Teaching in the Department of Biomedical Informatics for the year 2023. Congratulations!
[Dec-12-2023] Dr. Jordan Krull was awarded Excellence in Postdoc Research in the Department of Biomedical Informatics for the year 2023. Congratulations!
[Dec-5-2023] Mr. Shaopeng Gu has officially joined IOIG as a Biostatistics Senior Analyst. Welcome!
[Nov-29-2023] Lead by Xiaoying Wang, the paper titled “MarsGT: Multi-omics analysis for rare population inference using single-cell graph transformer” has been officially accepted for publication in Nature Communications.
[Nov-29-2023] Our manuscript “Dimension-agnostic and granularity-based spatially variable gene identification using BSP”, has been featured in Nature Communications Editors’ Highlights page among the top 50 papers in Biotechnology and methods.
[Nov-23-2023] The paper titled “mRNA vaccines against SARS-CoV-2 induce divergent antigen-specific T cell responses in lung cancer patients,” is accepted to be published in Journal for ImmunoTherapy of Cancer.
[Nov-15-2023] Our collaborative paper titled “Abnormal progenitor cell differentiation and cardiomyocyte proliferation in hypoplastic right heart syndrome,” is accepted to be published in Circulation (IF=40)!.
[Nov-13-2023] A new paper titled “DeepProSite: Structure-aware Protein Binding Sites Prediction Using ESMFold and Pre-trained Language Model,” is accepted to be published in Bioinformatics.
[Oct-13-2023] Dr. Qin Ma has offered his expert opinion for the Research Briefing accompanying the paper titled “STAligner: Enabling the Integration and Alignment of Multiple Spatial Transcriptomics Datasets” on Nature Computational Science.
[Jul-18-2023] Exciting development as our P01 program “Sex, Chromosomes, and Immunity in Bladder Cancer” (1P01CA278732) is officially launched! Visit our website at https://www.bcgsp.org/ to learn more about our latest research endeavors.
[Jul-6-2023] Yuzhou Chang has been honored with the Student & Trainee Travel Award at the International Conference on Intelligent Biology and Medicine (ICIBM 2023).
[Jul-6-2023] Our work leaded by Dr. Dongjun Chung, titled “LRT: Integrative Analysis of scRNA-seq and scTCR-seq Data to Investigate Clonal Differentiation Heterogeneity,” has been formally accepted for publication in PLOS Computational Biology.
[Jun-20-2023] Dr. Anjun Ma’s abstract, “Deep Transfer Learning of Cancer Drug Responses by Integrating Bulk and Single-cell RNA-seq data”, has been selected for a 10-minute flash talk at the International Conference on Intelligent Biology and Medicine (ICIBM 2023) on July 18th, 2023.
[Jun-1-2023] Yuzhou Chang is set to present an intriguing poster titled “Spatial omics feature representation using graph Fourier transform” at the Spatial Biology 2023 US Conference.
[May-21-2023] Congratulations to Xiaoying Wang for successfully completing her PhD dissertation! We commend her exceptional scholarly achievement and profound dedication to her academic journey.
[May-19-2023] Congratulations to Dr. Anjun Ma on his promotion to Clinical Assistant Professor! We celebrate his outstanding accomplishments and unwavering dedication to his field.
[May-19-2023] Congratulations to Dr. Qin Ma on his promotion to Full Professor by The Ohio State University! We celebrate his outstanding accomplishments and unwavering dedication to his field.
[May-4-2023] Dr. Jordan Krull had been selected as a Pelotonia Post-Doctoral Scholar through the Pelotonia Scholars Program. Congratulations to Dr. Krull on this achievement!
[Apr-19-2023] The poster “The tumor microbiome associates with features of the tumor microenvironment, treatment outcomes, and histologies; a national collaboration of the exORIEN Consortium” was presented at the 2023 American Association for Cancer Research Annual Meeting.
[Apr-06-2023] The IOIG team will give a presentation related to the newly published DeepMAPS and single-cell multi-omics data analysis on the ExpIO group meeting.
[Mar-28-2023] Dr. Xiaokui (Molly) Mo has officially joined IOIG. Welcome!
[Mar-22-2023] Our DeepMAPS paper is highlighted by Nature Communications editor, as one of the 50 best papers in the field of Cancer research published at Nature Communications.
[Feb-6-2023] The manuscript “Single-cell biological network inference using a heterogeneous graph transformer” is officially accepted for publication in Nature Communications!
[Jan-25-2023] The manuscript “Computational methods and challenges in analyzing intratumoral microbiome data” has been accepted for publication in Trends in Microbiology! This is the first immuno-oncology-microbiome paper in IOIG.
[Jan-5-2023] Dr. Qin Ma gave an invited presentation “Graph Fourier Transform for tissue module identification from spatial multi-omics” at the Pelotonia Institute for Immuno-Oncology (PIIO) experimental IO group meeting.
2022
[12/05/2022] Three new members, Dr. Jordan Krull, Dr. Hyeongseon (Sammy) Jeon, and Ms. Juan Xie have joined IOIG. Welcome aboard!
[10/20/2022] The manuscript “SUSD2 suppresses CD8+ T cell antitumor immunity by targeting IL-2 receptor signaling” has been published in Nature Immunology!
[10/18/2022] Yuzhou Chang gave an invited talk “Spatial transcriptomics algorithms and the trend of spatial omics” at MWACD 2022 annual meeting.
[08/24/2022] We are pleased to announce that a research paper entitled “Define and visualize pathological architectures of human tissues from spatially resolved transcriptomics using deep learning” has been officially published in Computational and Structural Biotechnology Journal.
[08/01/2022] IOIG is now recruiting new members! A Postdoc position and a Consultant 3 position are open to the public. Check here for more information.
[08/01/2022] Dr. Brain Searle has received an outstanding fundable score (8%) for his R21 proposal submitted to NIH/NCI. This project is proposed for identifying I-O therapeutic protein targets in Glioblastoma that are derived from alternative splicing using genomics and proteomics. Congrats!
[07/27/2022] We are pleased to announce that a research paper entitled “A Bayesian multivariate mixture model for high throughput spatial transcriptomics” has been officially published in Biometrics.
[Jul-29-2022] We are pleased to announce the appointment of Dr. Qin Ma as the Section Chief of Computational Biology and Bioinformatics in the Department of Biomedical Informatics, OSU.
[Jun-17-2022] We are pleased to announce that the Immuno-Oncology Informatics Group (IOIG) is founded today. Dr. Qin Ma is announced as the leader of IOIG. Please check the details here. Cheers!