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Bisht M*, Chung YC*, He SL, Willey S, Sunkel BD, Wang M, Stanton BZ, Tu LC. (2024) Differential regulation of large-scale chromosome conformation in osteoblasts and osteosarcoma. BioRxiv. 2024.11.01.621571. *Co-first authors
Liang Y, Willey S, Chung YC, Lo YM, Miao S, Tu LC†, Bong D†. (2023) Intracellular RNA and DNA tracking by uridine-rich internal loop tagging with fluorogenic bPNA. Nat. Commun. 14, 2987. †Co-corresponding authors
Chung YC, Tu LC. (2023) Interplay of dynamic genome organization and biomolecular condensates. Curr. Opin. Cell Biol. 85, 102252.
Thuma J*, Chung YC*, Tu LC. (2023) Advances and Challenges in CRISPR-based real-time imaging of dynamic genome organization. Front Mol Biosci. 10:1173545. doi: 10.3389/fmolb.2023.1173545
Chung YC, Bisht M, Thuma J, Tu LC. (2023) Single Chromosome Dynamics Reveals Locus-Dependent Dynamics and Chromosome Territory Orientation. J Cell Sci,.
Liang Y, Willey S, Chung YC, Lo YM, Miao S, Tu LC†, Bong D†. (2022) Fluorogenic U-rich internal loop (FLURIL) tagging with bPNA enables intracellular RNA and DNA tracking. BioRxiv, 2022.07.21.501035. †Co-corresponding authors
Chung YC, Bisht M, Tu LC. (2022) CRISPR-based multi-locus real-time tracking reveals single chromosome dynamics and compaction. BioRxiv, 478681.
Ma H*, Tu LC*, Chung YC*, Naseri A, Grunwald D, Zhang S, Pederson T. (2019) Cell cycle- and genomic distance-dependent dynamics of a discrete chromosomal region. J Cell Biol. 218(5): 1467-1477. *Co-first authors
Tu LC*, Huisman M*, Chung YC*, Smith C, Grunwald D. (2018) Deconstructing transport distribution reconstruction in the nuclear-pore complex. Nat. Struct. Mol. Biol. 25(12):1061-1062. *Co-first authors
Ma H, Tu LC, Naseri A, Chung YC, Grunwald D, Zhang S, Pederson T. (2018) CRISPR-Sirius: RNA scaffolds for signal amplification in genome imaging. Nat Methods. 15(11):928-931.
Gao XD, Tu LC, Mir A, Dekker J, Shaffer SA, Zhu LJ, Wolfe SA, Sontheimer EJ. (2018) C-BERST: Defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2. Nat Methods. 15(6):433-436
Fu G, Tu LC, Zilman A, Musser SM. (2017) Investigating molecular crowding within nuclear pores using polarization-PALM. eLife September 26; 6: e28716
Ma H*, Tu LC*, Naseri A, Huisman M, Zhang S, Wolfe S, Grunwald D, Pederson T. (2016) CRISPRCas9 nuclear dynamics and target recognition in living cells. J Cell Biol. 214(5): 529-537. Recommended by F1000Prime and Highlighted in the In Focus section in J. Cell Biol. *Co-first authors
Ma H, Tu LC, Naseri A, Huisman M, Grunwald D, Zhang S, Pederson T. (2016) Multiplexed labeling of genomic loci with dCas9 and engineered sgRNA using CRISPRainbow. Nat. Biotechnol. 34(5): 528-30. Highlighted on the NIH 4D Nucleome webpage
Smith C, Tu LC, Grunwald D. (2015). A 4D view on mRNA. Oncotarget 6: 28515-28516
Tu LC, Fu G, Zilman A, Musser SM. (2013) Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins. EMBO J. 32:3220-3230.
Tu LC, Musser SM. (2011) Single molecule studies of nucleocytoplasmic transport. Biochim Biophys Acta – Mol. Cell Research. 1813: 1607-1618
Sun C, Yang W, Tu LC, Musser SM. (2008) Single-molecule measurements of importin alpha/cargo complex dissociation at the nuclear pore. Proc Natl Acad Sci USA. 105: 8613-8618
Ng KY, Tu LC, Wang YS, Chan SI, Yu SS. (2008) Probing the hydrophobic pocket of the active site in the particulate methane monooxygenase (pMMO) from Methylococcus capsulatus (Bath) by variable stereoselective alkane hydroxylation and olefin epoxidation. Chembiochem. 9: 1116-1123.