Introduction
- Chlorothalonil is an organic compound used as a broad spectrum , non-systemic fungicide also used as pesticides , wood protect ,mold controller, acaricids.
- Mostly used to control fungi that affects agro crops.
- Products containing Chlorothalonil are sold under the names Echo , Bravo, Daconil.
- Its one of the top 3 fungicide in the USA
- First registered for use in 1997.
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Properties
Molecular Formula | C8Cl4N2 |
Molecular Mass | 265.90 g·mol−1 |
Appearance | white crystalline solid |
Desnsity | 1.8 g cm−3, solid |
IUPAC Name | 2,4,5,6-Tetrachlorobenzene-1,3-dicarbonitrile |
Synonyms | 2,4,5,6-Tetrachloroisophthalonitrile Bravo Daconil Tetrachloroisophthalonitrile Celeste Bronco Agronil Aminil |
How does Chlorothalonil work
The video explains the mode of action of chlorothalonil.
Chlorothalonil deactivates glutathione actions.
Toxicology Effects
Acute Toxicity
- Eye irritant
- Skin irritant
- Loss of muscle coordination
- Rapid breathing
- Bleeding nose
- Hyperactivity
Chronic Toxicity
- Kidney damage and tumors
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Is Chlorothalonil safe !
- Always follow label instructions.
- Wear personal protective equipments
- Avoid risk of inhalation, ingestion, and coming in contact with the skin
Metabolism of Chlorothalonil following Oral administration to Rats
Clinical cases
- Only few cases have been reported of adverse effects in humans.
- Contact dermatitis is the most frequent diagnosis.
References:
1.Andre, J. C., et al. (1991a). “Comparison of the Effects of Dose Level and Vehicle on the Dermal Absorption of 14C-Chlorothalonil by Male Rats
2. “Chlorothalonil”. Pubchem
Toxicity of Fungicides
Veterinary Toxicology: Basic and Clinical Principles: Third Edition, 2018
4. PESTICIDE USE IN U.S. CROP PRODUCTION: 1997 Archived 10 December 2006 at the Wayback Machine National Center for Food and Agricultural Policy, 1997