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Sclerotinia stem rot, or white mold of soybean, is a disease most commonly reported in high-yield soybeans in the North Central Region of the United States. Overall disease incidence and severity vary from year to year and from field to field. In Ohio, growers have faced localized outbreaks of this disease every year since 2009. Infection and disease development are favored by wet conditions and cool temperatures (<70°F) prior to, during, and following the flowering stage.