Publications

Publications (> 70), last updated on 8/1/2024)

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Most recent publications from the Ghadiali lab since 2021 are listed below:

1. Murthy, A., Rodriguez, L., Dimopoulos, T., Bui, S., Iyer, S., Chavez, K., Tomer, Y., Abraham, V., Cooper, C., Renner, D., Katzen, J., Bentley, I., Ghadiali, S.N., Englert, J.E., Weiss, S. and BeersM., Activation of Alveolar Epithelial ER Stress by β-Coronavirus Infection Disrupt Surfactant Homeostasis in Mice: Implications for Covid-19 Respiratory Failure, in press, American Journal of Physiology Lung Cellular Physiology, 2024.
2. Cho, Y., Fakhouri, F., Ballinger, M.N., Englert, J.E., Hayes, D., Kolipaka, A., Ghadiali, S.N., Magnetic Resonance Elastography and Computational Modeling Identify Heterogeneous Lung Biomechanical Properties during Cystic Fibrosis, preprint at Research Square, submitted to Biomechanics and Modeling in Mechanobiology, 21 March 2024, [https://doi.org/10.21203/rs.3.rs-4125891/v1]
3. Gabela-Zuniga, B., Shukla, V.C., Bobba, C., Higuita-Castro, N., Powell, H.M., Englert, J.E., Ghadiali, S.N., A Micro-scale Humanized Ventilator-on-a-Chip to Examine the Injurious Effects of Mechanical Ventilation, preprint at bioRxiv, submitted to Lab-on-a-Chip, 26 February 2024, doi: https://doi.org/10.1101/2024.02.26.582200
4. Yu, Y., Wang, C., Ye, S., Xu, Z., Lin, H., Texter, K., Shukla, V., Ghadiali, S.N., Ma, Q., Garg, V., Zhao, MT., Abnormal progenitor cell differentiation and cardiomyocyte proliferation in hypoplastic right heart syndrome, Circulation, 149:888–89, 2024.
5. Fei, Q., Shalosky, E., Barnes, R., Shukla, V., Ballinger, M.N., Farkas, L., Lee, R., Ghadiali, S.N., Englert, J.E., Macrophage-targeted lipid nanoparticle delivery of microRNA-146a to mitigate hemorrhagic shock-induced acute respiratory distress syndrome, ACS Nano, 17 (17), 16539-16552, 2023.
6. Salazar-Puerta, A., Rincon-Benavides, M., Cuellar-Gaviria, T., Aldana-Aroca, J., Das, D., Dodd, D., Deng, B., McComb, D.W., Ghadiali, S.N., Englert, J., Ortega-Pineda, L., Zepeda-Orozco, D., Vasquez-Martinez, G., Spencer, C., Wold, L., Higuita-Castro, N., Engineered extracellular vesicles derived from dermal fibroblasts attenuate inflammation in a murine model of acute lung injury, Advanced Materials, 35(8): 2210579, 2023
7. Fei, Q., Bentley, I., Ghadiali S.N., Englert, J., Pulmonary Drug Delivery for Acute Respiratory Distress Syndrome, Pulmonary Pharmacology and Therapeutics, 79: 102196, 2023.
8. Novak, C.M., Sethuraman, S., Luikart, K.L., Reader, B.,F., Wheat, J., Whitson, B., Ghadiali, S.N., Ballinger, M.N., Alveolar macrophages drive lung fibroblast function during idiopathic pulmonary fibrosis, American Journal of Physiology Lung Cellular Physiology, 324: L507-520, 2023.
9. Fakhouri, F., Joseph, M., Ballinger, M., Shukla, V., Weimar, D., Novak, C., Ghadiali, S.N., Kolipaka, A., MRE of Bleomycin Induced Pulmonary Fibrosis Animal Model, Investigative Radiology, 58(4): 299-306, 2023.
10. Nho, R.S., Ballinger, M.N., Rojas, M.M., Ghadiali, S.N., Horowitz, J.C., Biomechanical Force and Cellular Stiffness in Lung Fibrosis, The American Journal of Pathology, 192(5); 750-761, 2022.
11. Novak, C., Ballinger, M., Ghadiali, S.N., Mechanobiology of Pulmonary Diseases: A Review of Engineering Tools to Understand Lung Mechanotransduction, Journal of Biomechanical Engineering, 143(11);110801 (15 pages), Nov 2021.
12. Jones, C.E., Colbert, S.E., Shukla, V.C., Ostrowski, M.C., Ghadiali, S.N., Sizemore, S.T., Leight, J.L., Pten regulates collagen fibrillogenesis by fibroblasts through SPARC, PloS one 16(2):e0245653, 2021.
13. *Bobba, C., *Fei, Q., Shukla, V., Lee, H., Patel, P., Putman, R., Spitzer, C., Tsai, M., Wewers, M.D., Christman, J.W., Ballinger, M.,N., *Ghadiali, S., *Englert, J.A., Nanoparticle delivery of microRNA-146a regulates mechanotransduction in lung macrophages and mitigates lung injury during mechanical ventilation, 12(1): 1-13, Nature Communications, 2021.
14. Bobba, C.M., Nelson, K., Dumond, C., Eren, E., Black, S.M., Englert, J.A., *Ghadiali, S. N., *Whitson, B.A., Novel Pressure-Flow Waveforms to Resuscitate Lungs for Normothermic Ex-Vivo Lung Perfusion, ASAIO Journal, Jan 1;67(1):96-103, 2021.
15. Lee, H., Fei, Q., Streicher, A., Zhang, W., Isabelle, C., Patel, P., Lam, H., Pinilla-Vera, M., Amador-Munoz, D., Barragan-Bradford, D., Higuera-Moreno, A., Putman, R.K., Sholl, L.M., Henske, E.P., Bobba, C., Higuita-Castro, N., Hite, D., Christman, J.W., Ghadiali, S.N., Baron, R.M.*, Englert, J.A.*, Mechanosensitive activation of mTORC1 mediates ventilator induced lung injury during the acute respiratory distress syndrome, Journal of Clinical Insight, Jul 22; 6(14):e137708. Doi: 10.1172/jci.insight.137708, 2021.