Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair.

Liu J, Hanne J, Britton BM, Bennett J, Kim D, Lee JB, Fishel R.

Congratulations to the authors on their groundbreaking work visualizing MutS and MutL sliding clamps and for the first time a biophysical function for MutL.

https://www.nature.com/articles/nature20562