Publications

 

Complete Publication List

Most Recent

  • Fishel, R.   Mismatch Repair: Choreographing accurate strand excision.  2021.  Curr. Biol.  31:282-309
  • Crocker, K., J. London, R. Fishel, and R. Bundschuh.  Potential evolutionary advantage of a dissociative search mechanism in DNA mismatch repair. 2021.  Physical Review E.  103:052404
  • London, J., J. Martin-Lopez, I. Yang, J. Liu, J-B. Lee and R. Fishel. 2021.  Linker Domain Function Predicts Pathogenic MLH1 Missense Variants.  Proc. Nat. Acad. Sci, (USA).  118:e2019215118.
  • Yoder, K., A.J. Rabe, R. Fishel and R.C. LaRue. 2021. Strategies for targeting retroviral integration for safer gene therapy:  advances and challenges.  Front. Mol. Biosci.  8:662331
  • Kotlar, R.M., N.D. Jones, G. Senavirathne, A.M. Gardner, R.K. Messer, Y.Y. Tan, A.J. Rabe, R. Fishel, and K.E. Yoder. 2021.  Retroviral prototype foamy virus intasome binding to a nucleosome target does not determine integration efficiency.  J. Biol Chem. 296:100550.
  • Liu, J., R-G. Lee, B.M. Britton, J.A. London, K. Yang, J. Hanne, J-B. Lee and R. Fishel. 2019.  MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair.  Nature Comm.  10:5294
  • Mackler, R.M., N.D. Jones, A.M. Gardner, M.A. Lopez Jr, C.J. Howard, R. Fishel and K.E. Yoder.  2019.  Nucleosome DNA unwrapping does not affect prototype foamy virus integration efficiency or site selection.  PLoS One. 14:e0212764.
  • Van Oijen, A.M., K.E. Duderstadt, J. Xiao, R Fishel. 2018. Placticity of multi-protein complexes. J. Mol. Biol. 430:4441-4442.
  • Senavirathne, G., M.A. Lopez Jr., R. Messer, R. Fishel and K.E. Yoder. 2018. Expression and purification of nuclease-free Protocatechuate 3,4-Dioxygenase for prolonged single-molecule fluorescence imaging. Anal. Biochem.  556:78-84.
  • Liu, J., J.-B. Lee, and R. Fishel. 2018. Stochastic processes and component placticity governing DNA mismatch repair. J. Mol. Biol. 430:4456-4468.
  • Hanne, J., J. Park, B.M. Britton, J. Liu, M. Schoffner, P. Klajner, R. Bundschuh, J.-B. Lee and R. Fishel. 2018. MutS homolog sliding clamps shield the DNA from binding proteins J. Biol. Chem.  293:14285-14294.
  • Kar, A., N.D. Jones, O.N. Arat, R. Fishel, and J.D. Griffith. 2018. Long repeating (TTAGGG)n single stranded DNA self-condenses into compact beaded filaments stabilized by G-quadruplex formation. J. Biol. Chem. 293:9473-9485
  • Kim, D., R. Fishel, J.-B. Lee. 2018. Coordinating multi-protein DNA mismatch repair by managing diffusion mechanics on the DNA. J. Mol. Biol. 430:4469-4480.
  • Martín-López, J.V., P. Gasparini, K. Coomes, C.M. Croce, G. Boivin, and R. Fishel. 2018. Mutation of TGFβ-RII eliminates NSAID chemoprevention. Oncotarget. 9:12554-12561
  • Senavirathne, G., S. Mahto, J. Hanne, D. O’Brian and R. Fishel. 2017. Dynamic HsRAD51 interaction with nucleosomes induces sliding and rotational motion of histone octamers. Nucl Acids Res. 45:685-698.
  • Liu, J., J. Hanne, B.M. Britton, J. Bennett, D. Kim, J.-B. Lee, and R. Fishel. 2016. Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair. Nature. 539:583-587.
  • Fishel, R., and C.H. Heinen.  2016. Enhanced gene targeting to evaluate Lynch syndrome alterations. Proc. Nat. Acad. Sci. (USA). 113:3918-3920
  • Fishel, R., and J,-B. Lee.  2016. Mismatch Repair. In: DNA Replication, Recombination and Repair : Molecular Mechanisms and Pathology (Hanaoka and Sugasawa, Ed.) Springer, NY pp305-340.
  • Xu, B., R.J. Soukup, C. J. Jones, R. Fishel and D.J. Wozniak. 2016. Pseudomonas aeruginosa AmrZ binds to four sites in the algD promoter, inducing DNA-AmrZ complex formation and transcriptional activation. J. Bact. 198:2673-2681.
  • Jones, N.D., M.A. Lopez Jr., J. Hanne, M.B. Peake, J.-B. Lee, R. Fishel, and K.E. Yoder. 2016. Retroviral Intasomes Search a Target DNA by 1D-Diffusion. Nature Comm. 7: 11409.
  • Jeon, Y., D. Kim, J.V. Martín-López, J. Hanne, R. Fishel, J.-B. Lee. 2016. Dynamic control of strand excision during human DNA mismatch repair. Proc. Nat. Acad. Sci. (USA) 113:3281-3286.
  • Xu, B., Y. Ju, R.J. Soukup, D.M. Ramsey, R. Fishel and D.J. Wozniak. 2016.  The Pseudomonas aeruginosa AmrZ C-terminal domain mediates tetramerization and is required for its activator and repressor functions. Env. Microbiol. Rep. 8: 85-89.
  • Fishel, R. Mismatch Repair. J. Biol. Chem. 290:26395-26340.
  • Spies, M., and R. Fishel. 2015. Mismatch repair during homologous and homeologous recombination. In: Recombination Mechanism (Kowalczykowski and Heyer, Ed.) Cold Spring Harbor Press. 7:269-290.
  • Liu, J., J. Hanne, B.M. Britton, M. Shoffner, A.E. Albers, J. Bennett, R. Zatezalo, R. Barfield, D. Rabuka, J.-B. Lee and R. Fishel.  2015. An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore. Sci Reports. 5:16883.
  • Senavirathne, G., J. Liu, M.A. Lopez Jr., J. Hanne, J.V. Martin-Lopez, J-B. Lee, K.E. Yoder and R. Fishel. 2015. Widespread nuclease contamination in commonly used oxygen-scavenging systems. Nature Meth. 12:901-902.
  • Lee, J-.B., W-.K. Cho, J. Park, D. Kim, S.H. Lee, and Fishel. 2014. Single molecule views of MutS on mismatched DNA. DNA Repair. 20:82-93.
  • Bennett, G.R., R. Peters, X.H. Wang, J. Hanne, R.W. Sobol, R. Bundschuh, R. Fishel and K.E. Yoder. 2014. Repair of oxidative damage in the host genome influences the HIV integration site sequence preference. PLoS One. 9:e103164
  • Honda, M., Y. Okuno, S.R. Hengel, J.V. Martin-Lopez, C.P. Cook, R. Amunugama, R. Soukup, S. Subramanyam, R. Fishel and M. Spies. 2014. hMSH2-hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediate. Proc. Nat. Acad. Sci. (USA). 111:E316-25.
  • Martín-López, J.V., and R. Fishel. 2013. Understanding Lynch Syndrome: the mechanism of mismatch repair. Familial Cancer 12:159-168.
  • Hanne, J., J. Liu, J-.B. Lee and R. Fishel. 2013. Single-molecule FRET studies on DNA mismatch repair. J. Biophys. 3:18-38.
  • Amunugama, R., J. Groden and R. Fishel. 2013. The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filament. DNA Repair. 9:723-732.
  • North, J.A., R. Amunugama, W-D. Heyer, M. Poirier and R. Fishel. 2013. ATP-dependent nucleosome unwrapping catalyzed by human RAD51. Nucl. Acids Res. 41:7302-7312.