The Ohio State University: Wexner Medical Center

About Carrie Sims Lab

Welcome to Dr. Carrie Sims’ Lab!

In the Sims Lab, our research focuses on immunologic and metabolic changes in septic and hemorrhagic shock. We are particularly interested in the role of sirtuins, a family of proteins known to promote resilience to cellular stress, in preventing mitochondrial dysfunction in shock states. Additionally, our projects include testing engineered protein oxygen carriers as a potential replacement for blood transfusion in hemorrhagic shock.

Our Lab

: Alexandria Morton performing qPCR

: Hanna Labiner working with the Oroboros oxygraph-2k to measure mitochondrial respiration

: Our lab’s first annual tinfoil hat making competition. Congratulations to Kelli who won first place!

: Kelli Sas analyzing our newest exciting sirtuin data

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