Publications

2023
Microglia depletion facilitates the display of maternal behavior and alters activation of the maternal brain network in nulliparous female rats
Dye CN, Franceschelli D, Leuner B, Lenz KM (2023) Microglia depletion facilitates the display of maternal behavior and alters activation of the maternal brain network in nulliparous female rats. Neuropsychopharmacology 48(13):1869-1877.

The transition to motherhood: linking hormones, brain and behaviour
Servin-Barthet C, Martínez-García M, Pretus C, Paternina-Die M, Soler A, Khymenets O, Pozo ÓJ, Leuner B, Vilarroya O, Carmona S (2023) The transition to motherhood: linking hormones, brain and behaviour. Nat Rev Neurosci. 24(10):605-619.

Multiparity Differentially Affects Specific Aspects of the Acute Neuroinflammatory Response to Traumatic Brain Injury in Female Mice
Gilfarb R, Tapp Z, Lemanski E, Velasquez J, Cornelius S, Kokiko-Cochran ON, Leuner B (2023) Multiparity Differentially Affects Specific Aspects of the Acute Neuroinflammatory Response to Traumatic Brain Injury in Female Mice. Neuroscience 511:86-99.

2022
Immune System Alterations and Postpartum Mental Illness: Evidence From Basic and Clinical Research
Dye C, Lenz KM, Leuner B (2022) Immune System Alterations and Postpartum Mental Illness: Evidence From Basic and Clinical Research. Front Glob Womens Healt 2:758748.

Less can be more: Fine tuning the maternal brain
Pawluski JL, Hoekzema E, Leuner B, Lonstein JS (2022) Less can be more: Fine tuning the maternal brain. Neurosci Biobehav Rev. 133:104475.

GABA System Modifications During Periods of Hormonal Flux Across the Female Lifespan
Gilfarb RA, Leuner B (2022) GABA System Modifications During Periods of Hormonal Flux Across the Female Lifespan. Front Behav Neurosci 16:802530.

2021
GABA in the medial prefrontal cortex regulates anxiety-like behavior during the postpartum period
Sabihi S, Goodpaster C, Maurer S, Leuner B (2021) GABA in the medial prefrontal cortex regulates anxiety-like behavior during the postpartum period. Behav Brain Res 398:112967.

2020
Pregnancy, postpartum and parity: Resilience and vulnerability in brain health and disease
Deems NP, Leuner B (2020) Pregnancy, postpartum and parity: Resilience and vulnerability in brain health and disease. Front Neuroendocrinol 57:100820.

2019
Beyond the baby brain: Moving towards a better understanding of the parental brain and behavior
Brummelte S, Leuner B (2019) Beyond the baby brain: Moving towards a better understanding of the parental brain and behavior. Front Neuroendocrinol 54:100767.

Sex differences in the effects of early life stress exposure on mast cells in the developing rat brain
Joshi A, Page CE, Damante M, Dye CN, Haim A, Leuner B, Lenz KM (2019) Sex differences in the effects of early life stress exposure on mast cells in the developing rat brain. Horm Behav 113:76-84.

The long and short term effects of motherhood on the brain
Duarte-Guterman P, Leuner B, Galea LAM (2019) The long and short term effects of motherhood on the brain. Front Neuroendocrinol 53:100740.

The maternal reward system in postpartum depression
Post C, Leuner B (2019) The maternal reward system in postpartum depression. Arch Womens Ment Health 22(3):417-429.

2017
Oxytocin in the medial prefrontal cortex attenuates anxiety: Anatomical and receptor specificity and mechanism of action
Sabihi S, Dong SM, Maurer SD, Post C, Leuner B. Oxytocin in the medial prefrontal cortex attenuates anxiety: Anatomical and receptor specificity and mechanism of action. Neuropharmacology. 125:1-12.

The influence of offspring, parity, and oxytocin on cognitive flexibility during the postpartum period
Albin-Brooks C, Nealer C, Sabihi S, Haim A, Leuner B (2017) The influence of offspring, parity, and oxytocin on cognitive flexibility during the postpartum period. Horm Behav 89:130-136.

A survey of neuroimmune changes in pregnant and postpartum female rats
Haim A, Julian D, Albin-Brooks C, Brothers HM, Lenz KM, Leuner B (2017) A survey of neuroimmune changes in pregnant and postpartum female rats. Brain Behav Immun 59:67-78.

2016
The birth of new neurons in the maternal brain: Hormonal regulation and functional implications
Leuner B, Sabihi S (2016) The birth of new neurons in the maternal brain: Hormonal regulation and functional implications. Front Neuroendocrinol 41:99-113

The effects of gestational stress and Selective Serotonin reuptake inhibitor antidepressant treatment on structural plasticity in the postpartum brain–A translational model for postpartum depression
Haim A, Albin-Brooks C, Sherer M, Mills E, Leuner B (2016) The effects of gestational stress and SSRI antidepressant treatment on structural plasticity in the postpartum brain – A translational model for postpartum depression. Horm Behav 77:124-131.

2015
Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia
Pershing ML, Bortz DM, Pocivavsek A, Fredericks PJ, Jørgensen CV, Vunck SA, Leuner B, Schwarcz R, Bruno JP (2015) Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia. Neuropharmacology 90:33-41.

2014
Gestational stress induces persistent depressive-like behavior and structural modifications within the postpartum nucleus accumbens
Haim A, Sherer M, Leuner B (2014) Gestational stress induces persistent depressive-like behavior and structural modifications within the postpartum nucleus accumbens. Eur J Neurosci 40:3766-3773.

Hippocampal plasticity during the peripartum period: influence of sex steroids, stress and ageing
Galea LA, Leuner B, Slattery DA (2014) Hippocampal plasticity during the peripartum period: Influence of sex steroids, stress and ageing. J Neuroendocrinol 26:641-648.

Oxytocin in the medial prefrontal cortex regulates maternal care, maternal aggression and anxiety during the postpartum period
Sabihi S, Dong SM, Durosko NE, Leuner B (2014) Oxytocin in the medial prefrontal cortex regulates maternal care, maternal aggression and anxiety during the postpartum period. Front Behav Neurosci 8:258.

Photoperiodic regulation of hippocampal neurogenesis in adult male white-footed mice (Peromyscus leucopus)
Walton JC, Aubrecht TG, Weil ZM, Leuner B, Nelson RJ (2014) Photoperiodic regulation of hippocampal neurogenesis in adult male white-footed mice (Peromyscus leucopus). Eur J Neurosci 40:2674-2679.

Oxytocin in the prelimbic medial prefrontal cortex reduces anxiety-like behavior in female and male rats
Sabihi S, Durosko NE, Dong SM, Leuner B (2014) Oxytocin in the prelimbic medial prefrontal cortex reduces anxiety-like behavior in female and male rats. Psychoneuroendocrinology 45:31-42.

Chronic gestational stress leads to depressive-like behavior and compromises medial prefrontal cortex structure and function during the postpartum period
Leuner B, Fredericks PJ, Nealer C, Albin-Brooks C (2014) Chronic gestational stress leads to depressive-like behavior and compromises medial prefrontal cortex structure and function during the postpartum period. PLoS One 9:e89912.

2013
Stress, anxiety, and dendritic spines: what are the connections?
Leuner B, Shors TJ (2013) Stress, anxiety, and dendritic spines: What are the connections? Neuroscience 251:108-119.

2012
Oxytocin stimulates adult neurogenesis even under conditions of stress and elevated glucocorticoids
Leuner B, Caponiti JM, Gould E (2012) Oxytocin stimulates adult neurogenesis even under conditions of stress and elevated glucocorticoids. Hippocampus 22:861-868.

2010
Dendritic growth in medial prefrontal cortex and cognitive flexibility are enhanced during the postpartum period
Leuner B, Gould E (2010) Dendritic growth in medial prefrontal cortex and cognitive flexibility are enhanced during the postpartum period. J Neurosci 30:13499-13503.

Parenting and plasticity
Leuner B, Glasper ER, Gould E (2010) Parenting and plasticity. Trends Neurosci 33:465-73.

Sexual experience promotes adult neurogenesis in the hippocampus despite an initial elevation in stress hormones
Leuner B, Glasper ER, Gould E (2010) Sexual experience promotes adult neurogenesis in the hippocampus despite an initial elevation in stress hormones. PLoS One 5:e11597.

Structural plasticity and hippocampal function
Leuner B, Gould E (2010) Structural plasticity and hippocampal function. Annu Rev Psychol 61:111-140, C1-3.

Synapse Formation and Memory
Leuner B, Shors TJ (2010) Synapse formation and memory. In: Encyclopedia of Behavioral Neuroscience (Koob G, Thompson RF, LeMoal M, Eds), Elsevier.

Blockade of insulin-like growth factor-I has complex effects on structural plasticity in the hippocampus
Glasper ER, Llorens-Martín M, Leuner B, Gould E, Trejo JL (2010) Blockade of IGF-I has complex effects on structural plasticity in the hippocampus. Hippocampus 20:706-712.

2009
Thymidine analog methods for studies of adult neurogenesis are not equally sensitive
Leuner B, Glasper ER, Gould E (2009) Thymidine analog methods for studies of adult neurogenesis are not equally sensitive. J Comp Neurol 517:123-133.

2008
Adult neurogenesis finds its niche
Glasper ER, Leuner B, Gould E (2008) Adult neurogenesis finds its niche. Nat Neurosci 11:731.

2007
Maternal experience inhibits the production of immature neurons in the hippocampus during the postpartum period through elevations in adrenal steroids
Leuner B, Mirescu C, Noiman L, Gould E (2007) Maternal experience inhibits the production of immature neurons in the hippocampus during the postpartum period through elevations in adrenal steroids. Hippocampus 17:434-442.

Diminished adult neurogenesis in the marmoset brain precedes old age
Leuner B, Kozorovitskiy Y, Gross C, Gould E (2007) Diminished adult neurogenesis in the marmoset brain precedes old age. Proc Natl Acad Sci USA 104:17169-17173.

A critical time for new neurons in the adult hippocampus
Leuner B, Glasper ER, Mirescu C (2007) A critical time for new neurons in the adult hippocampus. J Neurosci 27:5845-5846.

2006
Learning during motherhood: A resistance to stress
Leuner B, Shors TJ (2006) Learning during motherhood: a resistance to stress. Horm Behav 50:38-51.

Temporal discontiguity is neither necessary nor sufficient for learning-induced effects on adult neurogenesis
Leuner B, Waddell J, Gould E, Shors TJ (2006) Temporal discontiguity is neither necessary nor sufficient for learning-induced effects on adult neurogenesis. J Neurosci 26:13437-13442.

Is there a link between adult neurogenesis and learning?
Leuner B, Gould E, Shors TJ (2006) Is there a link between adult neurogenesis and learning? Hippocampus 16:216-224.

2004
The opposite effects of stress on dendritic spines in male vs. female rats are NMDA receptor-dependent
Shors TJ, Falduto J, Leuner B (2004) The opposite effects of stress on dendritic spines in male versus female rats are NMDA receptor dependent. Eur J Neurosci 19:145-150.

High levels of estrogen enhance associative memory formation in ovariectomized females
Leuner B, Mendolia-Loffredo S, Shors TJ (2004) High levels of estrogen enhance associative memory formation in ovariectomized females. Psychoneuroendocrinology 29:883-890.

New spines, new memories
Leuner B, Shors TJ (2004) New spines, new memories. Molec Neurobiol 29:117-130.

Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory
Leuner B, Mendolia-Loffredo S, Kozorovitskiy Y, Samburg D, Gould E, Shors TJ (2004) Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory. J Neurosci 24:7477-7481.

Males and females respond differently to controllability and antidepressant treatment
Leuner B, Mendolia-Loffredo S, Shors TJ (2004) Males and females respond differently to controllability and antidepressant treatment. Biol Psychiatry 56:964-970.

2003
Associative memory formation increases the observation of dendritic spines in the hippocampus
Leuner B, Falduto J, Shors TJ (2003) Associative memory formation increases the observation of dendritic spines in the hippocampus. J Neurosci 23:659-665.

Estrogen-mediated effects on depression and memory formation in females
Shors TJ, Leuner B (2003) Estrogen-mediated effects on depression and memory formation in females. J Affect Disord 74:85-96.