Publications

Journal Publications

*a complete list of Dr. Kopec’s publications can be found on google scholar (https://scholar.google.com/citations?hl=en&user=ZQQTxPkAAAAJ&view_op=list_works&sortby=pubdate)

Li, Ziqi, Zhong, S., Kopec, R.E. 2024 Carotenoid Bioaccessibility and Caco-2 Cell Uptake Following Novel Encapsulation Using Medium Chain Triglycerides. Journal of Dietary Supplements. https://doi.org/10.1080/19390211.2024.2386255.

Zhong, S., Kopec, R.E. 2024 Bioaccessibility and Caco-2 Cell Uptake of Iron Chlorophyllin Using a Biologically Relevant Digestion Model. Journal of Nutritional Biochemistry. 132:109698. https://doi.org/10.1016/j.jnutbio.2024.109698

Parkinson, J.T., Cochran, H.J., Kieffer, J.D., Relling, A.E., Boyles, S.L., Kopec, R.E., Garcia, L.G. 2024. The effects of different feeding strategies providing different levels of vitamin A on animal performance, carcass traits, and the conversion rate of subcutaneous fat color in cull-cows. Translational Animal Science. 8:txae071. https://doi.org/10.1093/tas/txae071

Zhong, S., Mok, J.H., Li, Z., Sastry, S.K., Kopec, R.E. 2023. Production of iron-enriched kale leaves (Brassica oleracea L. var. acephala) utilizing combinations of novel food processing technologies. LWT 115365. https://doi.org/10.1016/j.lwt.2023.115365

Kopec, R.E., Chasman, D.I., Okereke, O.I., Sesso, H.D. 2023. Re-remembering the influence of randomized β-carotene on cognitive decline. Alzheimer’s & Dementia. In Press. https://doi.org/10.1002/alz.13018

Borel, P., Dangles, O., Kopec, R.E. 2023. Fat-soluble vitamin and phytochemical metabolites: Production, gastrointestinal absorption, and health effects. Progress in Lipid Research. 90:101220; https://doi.org/10.1016/j.plipres.2023.101220

Eroglu, A., Al’Abri, I., Kopec, R.E., Crook, N., Bohn, T. 2023. Carotenoids and their health benefits as derived via their interactions with gut microbiota. Advances in Nutrition. 14(2):238-255 https://doi.org/10.1016/j.advnut.2022.10.007

Toomey, M.B., Marques, C.I., Araújo, P.M., Huang, D., Zhong, S., Liu, Y., Schreiner, G.D., Myers, C.A., Paulo Pereira, Afonso, S., Andrade, P., Gazda, M.A., Lopes, R.J., Viegas, I. Koch, R.E., Haynes, M.E., Smith, D.J., Ogawa, Y., Murphy, D., Kopec, R.E., Parichy, D.M., Carneiro, M., Corbo, J.C. 2022. A mechanism for red coloration in vertebrates. Current Biologyhttps://doi.org/10.1016/j.cub.2022.08.013

Chatelaine, H.*, Ramazani, C.§, Spencer, K., Olivo-Marston, S., Bailey, M.T., McElroy, J., Hatzakis, E., Mathé, E., Kopec, R.E. 2022. Dietary Energy Intake and Presence of Aberrant Crypt Foci are Associated with Phospholipid, Purine, and Taurine Metabolite Abundances in C57BL/6N Mouse Colon. Molecular Nutrition and Food Research. 66:2200180; https://doi/10.1002/mnfr.202200180

Orchard, T.S., Kopec, R.E., Lohman, M. 2022. Inflammatory Potential of Diet and Aging – Including Frailty, Bone Health (density/fractures), Cataract, Frailty, and Cognitive Decline. In: Diet, Inflammation and Health (Eds. J.R. Hebert & L. Hofseth).

Korgaonkar, A., Han, C., Lemire, A., Siwanowicz, I., Bennouna, D., Kopec, R.E., Andolfatto, A., Truman, J., Shigenobu, S., Stern, D.L. 2021. Novel aphid genes contribute to plant gall development. Current Biology. https://doi.org/10.1016/j.cub.2021.01.104

Zhong, S., Bird, A., Kopec, R.E. 2021. The metabolism and potential bioactivity of chlorophyll and metallo-chlorophyll derivatives in the gastrointestinal tract. Molecular Nutrition and Food Research. doi: 10.1002/mnfr.202000761

Hammaz, F., Charles, F., Kopec, R.E., Halimi, C., Fgaier, S., Aarrouf, J., Urban, L., Borel, P. 2021. Temperature and storage time increase provitamin A carotenoid concentrations and bioaccessibility in post-harvest carrots. Food Chemistry. https://doi.org/10.1016/j.foodchem.2020.128004

Sasaki, G.Y., Li, J., Cichon, M.J., Kopec, R.E., Bruno, R.S. 2020. Catechin-rich green tea extract and the loss-of-TLR4 signaling differentially alter the hepatic metabolome in mice with nonalcoholic steatohepatitis. Molecular Nutrition and Food Research. https://doi.org/10.1002/mnfr.202000998

Chatelaine, H., Dey, P., Mo., X., Mah, E. Bruno, R., Kopec, R.E. 2021. Vitamin A and D Absorption in Adults with Metabolic Syndrome vs. Healthy Controls – A Pilot Study Utilizing Targeted and Untargeted LC-MS Lipidomics. Molecular Nutrition and Food Researchhttps://doi.org/10.1002/mnfr.202000413

Jonnala, B.R.Y., McSweeney, P.L.H., Cotter, P.D., Zhong, S., Sheehan, J.J., Kopec, R.E. 2021. Comparison of the carotenoid profiles of commonly consumed smear-ripened cheeses. LWT. https://doi.org/10.1016/j.lwt.2020.110241

Wang, C., Timári, I., Zhang, B., Li, D.-W., Leggett, A., Amer, A.O., Brüschweiler-Li, L., Kopec, R.E., Brüschweiler, R. 2020. COLMAR Lipids Database for 2D NMR-Based Lipidomics. Journal of Proteome Research 19 (4), 1674-1683; https://doi.org/10.1021/acs.jproteome.9b00845

Harrison, E.H., Kopec, R.E., 2020. Enzymology of vertebrate carotenoid oxygenases. Biochimica et Biophysica Acta. 1865(11); 158653; https://doi.org/10.1016/j.bbalip.2020.158653 

Sasaki, G.Y., Li, J., Cichon, M.J., Riedl, K.M., Kopec R.E., Bruno, R.S. 2019. Green tea extract treatment in obese mice with nonalcoholic steatohepatitis restores the hepatic metabolome in association with limiting endotoxemia-TLR4-mediated inflammation. Molecular Nutrition and Food Research. 63(24):e1900811; https://doi.org/10.1002/mnfr.201900811

Bennouna, D., Solano, M. , Orchard, T., DeVries, A.C., Lustberg, M., Kopec, R.E. 2019. The effects of doxorubicin-based chemotherapy and omega-3 supplementation on mouse brain lipids. Metabolites. 9(10), 208; https://doi.org/10.3390/metabo9100208

Zhong, S., Vendrell-Pacheco, M., Heskitt, B., Chitchomroonchokchai, C., Elez-Martinez, P., Failla, M.L., Sastry, S., Kopec, R.E. 2019. Novel processing technologies as compared to thermal treatment on the bioaccessibility and Caco-2 cell uptake of carotenoids from tomato and kale-based juices. Journal of Agricultural and Food Chemistry. 67(36):10185-10194; https://pubs.acs.org/doi/full/10.1021/acs.jafc.9b03666

Kopec, R.E., Caris-Veyrat, C., Nowicki, M., Bernard, J.P., Morange, S., Chitchumroonchokchai, C., Gleize, B., Borel, P. 2019. The effect of supplemental iron on lycopene metabolism and absorption during digestion in healthy humans. Molecular Nutrition and Food Research. 63(22):e1900644; https://doi.org/10.1002/mnfr.201900644.R2

Grainger E.M., Moran, N.E., Francis, D.M., Schwartz, S.J., Wan, L., Thomas-Ahner, J., Kopec, R.E., Riedl, K.M., Young, G.S., Abaza, R., Bahnson, R.R., Clinton, S.K. 2018. A novel tomato-soy juice induces a dose-response increase in urinary and plasma phytochemical biomarkers in men with prostate cancer. Journal of Nutrition. 149(1):26-35; https://doi.org/10.1093/jn/nxy232

Kopec, R.E., Carail, M., Caris-Veyrat, C. 2018. Production, separation, and characterization of apo-luteinoids by LC-MS/MS. Journal of Chromatography B. 1102:45-51. https://doi.org/10.1016/j.jchromb.2018.09.036

Harrison E.H., Kopec, R.E., Digestion and intestinal absorption of dietary carotenoids and vitamin A. In: Physiology of the Gastrointestinal Tract, Volume II, H.M. Said, F.K. Ghishan, J.D. Kaunitz, J.L. Merchant, J.L., J.D. Wood, eds. 6th Ed. Oxford, England: Academic Press. 2018. 1133-1151

Kopec, R.E., Caris-Veyrat, C., Nowicki, M., Gleize, B., Carail, M., Borel, P. 2018. Production of asymmetric oxidative metabolites of 13C β-carotene during digestion in the gastrointestinal lumen of healthy men. American Journal of Clinical Nutrition. 108(4):803-813. https://doi.org/10.1093/ajcn/nqy183

Kopec, R.E., Failla, M.L., 2018. Recent advances in the bioaccessibility and bioavailability of carotenoids and effects of other dietary lipophiles. Journal of Food Composition and Analysis. 68:16-30; https://doi.org/10.1016/j.jfca.2017.06.008

Cooperstone, J.L., Goetz, H.J., Riedl, K.M., Harrison, E.H., Schwartz, S.J., Kopec, R.E. 2017. Relative contribution of α-carotene to postprandial vitamin A concentrations in healthy humans after carrot consumption. American Journal of Clinical Nutrition. 106(1):59-66; https://doi.org/10.3945/ajcn.116.150821

Kopec, R.E., Gleize, B., Borel, P. Demarchelier, C., Caris-Veyrat, C. 2017. Are lutein, lycopene, and β-carotene lost through the digestive process?  Food and Function. 8:1494-1503; https://doi.org/10.1039/C7FO00021A

Desmarchelier, C., Borel, P., Gonclaves, A., Kopec. R., Nowicki, M., Morange, S., Lesavre, N., Portugal, H., Reboul, E. 2016. A combination of single-nucleotide polymorphisms is associated with the interindividual variability in cholecalciferol bioavailability in healthy men. Journal of Nutrition. 146(12):2421-2428; https://doi.org/10.3945/jn.116.237115

Goetz, H.J., Kopec, R.E., Riedl, K.M., Cooperstone, J.L., Narayanasamy, S., Curley, R.W. Jr., Harrison, E.H., Schwartz, S.J. 2016. An HPLC-MS/MS method for the separation of α-retinyl esters from retinyl esters. Journal of Chromatography B. 1029:68-71;  https://doi.org/10.1016/j.jchromb.2016.06.043