Journal Publications

*a complete list of Dr. Kopec’s publications can be found on google scholar (

Zhong, S., Bird, A., Kopec, R.E. 2020. The metabolism and potential bioactivity of chlorophyll and metallo-chlorophyll derivatives in the gastrointestinal tract. Molecular Nutrition and Food Research. In review.

Sasaki, G.Y., Li, J., Cichon, M.J., Kopec, R.E., Bruno, R.S. 2020. Catechin-rich green tea extract and the loss-of-TLR4 signaling differentially alter the hepatic metabolome in mice with nonalcoholic steatohepatitis. Molecular Nutrition and Food Research.

Chatelaine, H., Dey, P., Mo., X., Mah, E. Bruno, R., Kopec, R.E. 2020. Vitamin A and D Absorption in Adults with Metabolic Syndrome vs. Healthy Controls – A Pilot Study Utilizing Targeted and Untargeted LC-MS Lipidomics. Molecular Nutrition and Food Research

Jonnala, B.R.Y., McSweeney, P.L.H., Cotter, P.D., Zhong, S., Sheehan, J.J., Kopec, R.E. Comparison of the carotenoid profiles of commonly consumed smear-ripened cheeses. LWT.

Hammaz, F., Charles, F., Kopec, R.E., Halimi, C., Fgaier, S., Aarrouf, J., Urban, L., Borel, P. 2020. Temperature and storage time increase provitamin A carotenoid concentrations and bioaccessibility in post-harvest carrots. Food Chemistry.

Wang, C., Timári, I., Zhang, B., Li, D.-W., Leggett, A., Amer, A.O., Brüschweiler-Li, L., Kopec, R.E., Brüschweiler, R. 2020. COLMAR Lipids Database for 2D NMR-Based Lipidomics. Journal of Proteome Research 19 (4), 1674-1683;

Harrison, E.H., Kopec, R.E., 2020. Enzymology of vertebrate carotenoid oxygenases. Biochimica et Biophysica Acta. 1865(11); 158653; 

Sasaki, G.Y., Li, J., Cichon, M.J., Riedl, K.M., Kopec R.E., Bruno, R.S. 2019. Green tea extract treatment in obese mice with nonalcoholic steatohepatitis restores the hepatic metabolome in association with limiting endotoxemia-TLR4-mediated inflammation. Molecular Nutrition and Food Research. 63(24):e1900811;

Bennouna, D., Solano, M. , Orchard, T., DeVries, A.C., Lustberg, M., Kopec, R.E. 2019. The effects of doxorubicin-based chemotherapy and omega-3 supplementation on mouse brain lipids. Metabolites. 9(10), 208;

Zhong, S., Vendrell-Pacheco, M., Heskitt, B., Chitchomroonchokchai, C., Elez-Martinez, P., Failla, M.L., Sastry, S., Kopec, R.E. 2019. Novel processing technologies as compared to thermal treatment on the bioaccessibility and Caco-2 cell uptake of carotenoids from tomato and kale-based juices. Journal of Agricultural and Food Chemistry. 67(36):10185-10194;

Kopec, R.E., Caris-Veyrat, C., Nowicki, M., Bernard, J.P., Morange, S., Chitchumroonchokchai, C., Gleize, B., Borel, P. 2019. The effect of supplemental iron on lycopene metabolism and absorption during digestion in healthy humans. Molecular Nutrition and Food Research. 63(22):e1900644;

Grainger E.M., Moran, N.E., Francis, D.M., Schwartz, S.J., Wan, L., Thomas-Ahner, J., Kopec, R.E., Riedl, K.M., Young, G.S., Abaza, R., Bahnson, R.R., Clinton, S.K. 2018. A novel tomato-soy juice induces a dose-response increase in urinary and plasma phytochemical biomarkers in men with prostate cancer. Journal of Nutrition. 149(1):26-35;

Kopec, R.E., Carail, M., Caris-Veyrat, C. 2018. Production, separation, and characterization of apo-luteinoids by LC-MS/MS. Journal of Chromatography B. 1102:45-51.

Harrison E.H., Kopec, R.E., Digestion and intestinal absorption of dietary carotenoids and vitamin A. In: Physiology of the Gastrointestinal Tract, Volume II, H.M. Said, F.K. Ghishan, J.D. Kaunitz, J.L. Merchant, J.L., J.D. Wood, eds. 6th Ed. Oxford, England: Academic Press. 2018. 1133-1151

Kopec, R.E., Caris-Veyrat, C., Nowicki, M., Gleize, B., Carail, M., Borel, P. 2018. Production of asymmetric oxidative metabolites of 13C β-carotene during digestion in the gastrointestinal lumen of healthy men. American Journal of Clinical Nutrition. 108(4):803-813.

Kopec, R.E., Failla, M.L., 2018. Recent advances in the bioaccessibility and bioavailability of carotenoids and effects of other dietary lipophiles. Journal of Food Composition and Analysis. 68:16-30;

Cooperstone, J.L., Goetz, H.J., Riedl, K.M., Harrison, E.H., Schwartz, S.J., Kopec, R.E. 2017. Relative contribution of α-carotene to postprandial vitamin A concentrations in healthy humans after carrot consumption. American Journal of Clinical Nutrition. 106(1):59-66;

Kopec, R.E., Gleize, B., Borel, P. Demarchelier, C., Caris-Veyrat, C. 2017. Are lutein, lycopene, and β-carotene lost through the digestive process?  Food and Function. 8:1494-1503;

Desmarchelier, C., Borel, P., Gonclaves, A., Kopec. R., Nowicki, M., Morange, S., Lesavre, N., Portugal, H., Reboul, E. 2016. A combination of single-nucleotide polymorphisms is associated with the interindividual variability in cholecalciferol bioavailability in healthy men. Journal of Nutrition. 146(12):2421-2428;

Goetz, H.J., Kopec, R.E., Riedl, K.M., Cooperstone, J.L., Narayanasamy, S., Curley, R.W. Jr., Harrison, E.H., Schwartz, S.J. 2016. An HPLC-MS/MS method for the separation of α-retinyl esters from retinyl esters. Journal of Chromatography B. 1029:68-71;