The overarching goal of our research is to develop technologies using mass spectrometry-based metabolomics, in combination with advanced chemometrics, for the sensitive, reliable and non-invasive detection and monitoring of human diseases, and to aid the current understanding of complicated disease mechanism, which could ultimately promote the rapid and non-invasive disease detection and discoveries of novel therapeutic targets.
Specific area of interests of our group are listed below:
Research interest 1: Developing a multiplex metabolomics platform for both global and targeted metabolic profiling that are suitable for both human and microbiome studies.
Research interest 2: Applying multiplex metabolic profiling platform to decipher lung cancer metabolism and identify lung cancer biomarkers.
Research interest 3: Applying metabolic profiling approach to understand the host-pathogen interaction: start from colorectal cancer intestinal bacteria and their influence on colorectal cancer disease development/progression.
Research interest 4: Applying in vitro and in vivo models to understand the metabolic functions of human microbiome.
