Lab Gallery

2019 Holiday Party


Potentially Harmful Heart Effects Caused By Various Aspects Of Smoking E-Cigarettes

There are many variables that play a role in e-cigarette vapour composition, including the propylene glycol to glycerine ratio, manufacturer of the e-liquid, type of e-cigarette, coil temperature, air flow rate, nicotine content, and the flavorings added to the e-liquids. The potential cardiovascular effects associated with these compounds and their additive effects are summarized in the above graphic.

 

NBC Cleveland WKYC Interview

We’re all aware of the benefits exercise and diet can have on our health, especially on the effects of weight gain. What if we told you that your relationship with the environment around you also affects multiple facets of your body’s biology? In this special feature with WKYC, Dr. Wold discusses the different impacts air pollution can have on our bodies, our weight, cardiac issues, and even our future generations. For the full interview of Dr. Wold, please click here.

March 18, Dr. Wold had the outstanding opportunity to interview with Phil Trexler of NBC WKYC. The two discussed the cardiac and overall health effects that air pollution can have on the human body. This interview was shot for a segment of a television special linked above.
Dr. Wold shared fascinating information about results that could change the way we think about air pollution and how we live our daily lives. In a cliff note, Dr. Wold addresses how air pollution in large cities around the world, such as Los Angeles, and Beijing, can increase obesity rates and genetically mutate areas of the heart.  Throughout the interview, Dr. Wold emphasized that our lab’s research is important because of the implications it can have on the health of our future generations. Dr. Wold also had a chance to show off his lab skills handling mice as he explained our lab’s research methods.
You’re not going to want to miss Dr. Wold’s interview with NBC WKYC airing this Spring, in which he discusses significant results and their implications on our health. It was a privilege to have Mr. Trexler and his team spotlight our efforts.

2018 Holiday Dinner

The Wold lab celebrated the holiday season together with an extravagant dinner at Columbus’ famous Jeff Ruby’s Steakhouse. Pictured below is Dr. Wold giving a heartfelt speech thanking his staff for the pivotal year we’ve had within our lab.

Dr. Wold and his lab enjoying their filet mignons from Jeff Ruby’s Steakhouse. We shared a spectacular night reminiscing over our favorite memories and accomplishments.

The smiles and steaks are just as big from the other side of the table! There was silence throughout dinner as everyone’s attention became absorbed by the taste of their meals. The only time someone spoke was in-between bites to say how good their food was.

The Wold Lab outside Jeff Ruby’s with full bellies after our outstanding dinner! Dr. Wold’s treat to a nice night out with the entire lab was the perfect way to wrap up the year and kick off 2019 on the right foot. The Wold lab never skipped a beat when researching certain cardiac effects this year, and the momentum has only continued to grow.

Exposure Equipment

Particulate Matter Exposures On Alzheimer’s Mice

In a nutshell, our equipment is designed to pull in polluted air from outside our lab’s building and filter anything that’s not the particulate matter we’re looking for. There’s a parking garage next door so it’s the ideal location to collect particulate matter.

Filtered Air Exposure On Mice

Certain chambers are exposed to air which is even cleaner than what we all breathe. These mice are our controlled variable. The results we find within the Alzheimer’s mice will be contrasted with the results of these mice. The conclusion will provide supporting evidence to groundbreaking research involving the cardiac effects of Alzheimer’s disease.

Exposure Pump Set-Up

This complex contraption is what’s responsible for bringing in the polluted air from outside, and concentrating it into the appropriate particulate matter that our research requires. When the polluted air is inhaled by the equipment it goes into a hot bath where the pollution is saturated and condensed into varying sizes of particulate matter. The particulate matter is then chilled and concentrated into the specific size we desire to test (PM < 2.5µm in diameter). The particles that aren’t saturated enough, or are too saturated are then dispersed back outside.

Exposure Equipment Within Fume Hood

Within this fume hood is where we test the cardiac effects of smoking e-cigarettes. The results of this experiment will blaze the trail for future inquiries, and investigative studies involving the trendy topics of Juuls and other e-cigarette brands.

The Exposure Equipment

We are utilizing a mouse model, exposing them to e-liquid vapor from the chamber. This is similar to what e-cigarette users experience when taking a puff of their device.
The trigger plunger activates the e-cigarette unit by pressing the button 1/min. The coil of the “e-cig” unit heats the e-liquid in the chamber, and the smoke chamber inhales the vapor that is distributed to the exposure chambers.