DNA Origami is a nanotechnology used to create static and dynamic structures.
The known sequencing and base pairing of DNA allows for the design of an infinite number of possibilities. 3D origami structures can have many uses, such as delivering medicine to cancer cells or measuring distances and forces. When folding DNA, an excess amount of materials is used to account for structures that did not form completely or aggregated together. These unwanted materials in solutions are unwanted and inhibit the execution of successful experimentation.
The student handout will be given to all students working on the design challenge. It gives a brief recap of the story, it helps the students identify what they are attempting to achieve, and it recaps the design process.
Purifying DNA Origami TEK8 Instructor’s Guide
This Instructor’s Guide provides the instructor additional information on how to run the design challenge with alternatives for materials and test setups as well as information to help make the design challenge a good educational experience.
The Telling the Story Video conveys the societal impact of the student’s research that is the basis for the design challenge and will set the problem-solving context for students.
The Design Challenge Video leads students through the design process. It indicates materials available, states what the criteria are for success and any constraints. It also gives a second ‘level’ of the design challenge that allows ‘early completers’ to move on to a slightly more difficult challenge.Purifying DNA Origami