Our research focus is to establish the molecular identity of mitochondrial ion channels, elucidate their targeting mechanism and study their biophysical properties. At functional level we focus on how mitochondrial ion channels regulate cellular physiology by altering the mitochondrial properties. To understand their role in health and disease, our group is focused on their role in cardioprotection from ischemia-reperfusion injury and functional role in the aging heart. The specific projects are:

  • Molecular identity and regulation of mitochondrial ion channels
  • Regulation of mitochondrial structure and function by mitochondrial ion channels
  • Role of mitochondrial ion channels in cardioprotection from ischemia-reperfusion injury.
  • Role of mitochondrial ion channels in regulation of cardiac function and aging.