Publications

 

  • Jerome AD, Sas AR, Wang Y, Hammond LA, Wen J, Atkinson JR, Webb A, Liu T, Segal BM. Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration. Nat Immunol. 2024 Jun;25(6):957-968. doi: 10.1038/s41590-024-01836-7. Epub 2024 May 29. PMID: 38811815.
  • Roy D, Dion E, Sepeda JA, Peng J, Lingam SR, Townsend K, Sas A, Sun W, Tedeschi A. α2δ1-mediated maladaptive sensory plasticity disrupts adipose tissue homeostasis following spinal cord injury. Cell Rep Med. 2024 May 21;5(5):101525. doi: 10.1016/j.xcrm.2024.101525. Epub 2024 Apr 24. PMID: 38663398.
  • Clayton BLL, Kristell JD, Allan KC, Cohn EF, Karl M, Jerome AD, Garrison E, Maeno-Hikichi Y, Sturno AM, Kerr A, Shick HE, Sepeda JA, Freundt EC, Sas AR, Segal BM, Miller RH, Tesar PJ. A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity. Nat Neurosci. 2024 Apr;27(4):656-665. doi: 10.1038/s41593-024-01580-z. Epub 2024 Feb 20. PMID: 38378993.
  • Labiner HE, Sas KM, Hoying J, Sepeda JA, Wolf N, Perez EC, Sas AR, Sims CA. SIRT1 DOWNREGULATION IN PNEUMONIA IS ASSOCIATED WITH AN IMMATURE NEUTROPHIL RESPONSE AND INCREASED DISEASE SEVERITY. J Trauma Acute Care Surg. 2023 Nov 13. doi: 10.1097/TA.0000000000004212. Epub ahead of print. PMID: 37962211.
  • Rajendran S, Hu Y, Canella A, Peterson C, Gross A, Cam M, Nazzaro M, Haffey A, Serin-Harmanci A, Distefano R, Nigita G, Wang W, Kreatsoulas D, Li Z, Sepeda JA, Sas A, Hester ME, Miller KE, Elemento O, Roberts RD, Holland EC, Rao G, Mardis ER, Rajappa P. Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma. Cell Rep. 2023 Mar 28;42(3):112197. doi: 10.1016/j.celrep.2023.112197. Epub 2023 Mar 3. PMID: 36871221.
  • Gardner AM, Atkinson JR, Wilkinson NM, Jerome AD, Bellinger CE, Sas AR, Segal BM. TAM receptor signaling dictates lesion location and clinical phenotype during experimental autoimmune encephalomyelitis. J Neuroimmunol. 2023 Feb 15;375:578016. doi: 10.1016/j.jneuroim.2023.578016. Epub 2023 Jan 20. PMID: 36708633.
  • Blaszkiewicz M, Gunsch G, Willows JW, Gardner ML, Sepeda JA, Sas AR, Townsend KL. Adipose Tissue Myeloid-Lineage Neuroimmune Cells Express Genes Important for Neural Plasticity and Regulate Adipose Innervation. Front Endocrinol (Lausanne). 2022 Jun 20;13:864925. doi: 10.3389/fendo.2022.864925. PMID: 35795142; PMCID: PMC9251313.
  • Atkinson JR, Jerome AD, Sas AR, Munie A, Wang C, Ma A, Arnold WD, Segal BM. Biological aging of CNS-resident cells alters the clinical course and immunopathology of autoimmune demyelinating disease. JCI Insight. 2022 Jun 22;7(12):e158153. doi: 10.1172/jci.insight.158153. PMID: 35511417; PMCID: PMC9309055.
  • Popovich M, Almeida A, Freeman J, Eckner JT, Alsalaheen B, Lorincz M, Sas A. Use of Supervised Exercise During Recovery Following Sports-Related Concussion. Clin J Sport Med. 2021 Mar 1;31(2):127-132. doi: 10.1097/JSM.0000000000000721. PMID: 30768444.
  • Jerome AD, Atkinson JR, McVey Moffatt AL, Sepeda JA, Segal BM, Sas AR. Characterization of Zymosan-Modulated Neutrophils With Neuroregenerative Properties. Front Immunol. 2022 May 30;13:912193. doi: 10.3389/fimmu.2022.912193. PMID: 35711408; PMCID: PMC9195616.
  • Sas AR, Carbajal KS, Jerome AD, Menon R, Yoon C, Kalinski AL, Giger RJ, Segal BM. A new neutrophil subset promotes CNS neuron survival and axon regeneration. Nat Immunol. 2020 Dec;21(12):1496-1505. doi: 10.1038/s41590-020-00813-0. Epub 2020 Oct 26. PMID: 33106668; PMCID: PMC7677206.
  • Sas AR, Bimonte-Nelson H, Smothers CT, Woodward J, Tyor WR. Interferon-alpha causes neuronal dysfunction in encephalitis. J Neurosci. 2009 Mar 25;29(12):3948-55. doi: 10.1523/JNEUROSCI.5595-08.2009. PMID: 19321791; PMCID: PMC3598587.
  • Sas AR, Bimonte-Nelson H, Smothers CT, Woodward J, Tyor WR. Interferon-alpha causes neuronal dysfunction in encephalitis. J Neurosci. 2009 Mar 25;29(12):3948-55. doi: 10.1523/JNEUROSCI.5595-08.2009. PMID: 19321791; PMCID: PMC3598587.
  • Rao VR, Sas AR, Eugenin EA, Siddappa NB, Bimonte-Nelson H, Berman JW, Ranga U, Tyor WR, Prasad VR. HIV-1 clade-specific differences in the induction of neuropathogenesis. J Neurosci. 2008 Oct 1;28(40):10010-6. doi: 10.1523/JNEUROSCI.2955-08.2008. PMID: 18829958; PMCID: PMC2572723.
  • Sas AR, Bimonte-Nelson HA, Tyor WR. Cognitive dysfunction in HIV encephalitic SCID mice correlates with levels of Interferon-alpha in the brain. AIDS. 2007 Oct 18;21(16):2151-9. doi: 10.1097/QAD.0b013e3282f08c2f. Erratum in: AIDS. 2008 Feb 19;22(4):555. PMID: 18090041.