Lauren has been with the lab for one year and is currently working on the AR splice variants in HCC project, but she will soon be expanding to other projects within the lab. Lauren also does most of the lab ordering and helps with other administrative/managerial tasks.
Before coming to the Phelps Coss Lab, Lauren worked in fermentation and hematology labs. She has a BS in Microbiology from The Ohio State University.
Zhiliang (Leon) Xie is a Research Scientist with the Phelps Lab. He chose to work with the Phelps lab because of their highly focused research team and the opportunity to work with lab mates from many cultural backgrounds. Leon is currently working on LC-MS/MS and Elisa method development.
Hanna Radomska, PhD. Research Scientist Radomska.1@osu.edu
Dr. Hanna Radomska is a Research Scientist within the Comprehensive Cancer Center at The Ohio State University. She has an extensive experience in the field of hematology/oncology with the vast understanding of the role of transcription factors and signaling pathways in oncological diseases. She has years of experience in molecular biology, including CRISPR technology.
Currently, she is involved in multiple projects focused on cancer cachexia, estrogen receptor (ER) signaling, and the role of androgen receptor (AR) in HCC, with the aim of development of novel and effective therapeutic interventions. Her role on the proposed project involves genetic modification of model HCC cell lines using CRISPR methodology. She is creating AR-null and AR-overexpressing HCC cell lines, which will be used for in vivo studies to evaluate the roles of AR full length (AR-FL) and splice variants (AR-SV) in HCC tumorigenicity and testing responsiveness of those HCC tumors to AR-targeted therapies.
Her education includes: Gdańsk University, Gdańsk, Poland; M.Sc.; 10/1980 Biology Columbia University, New York, N.Y.; M.Phil.; 05/1992 Molecular Biology Columbia University, New York, N.Y.; Ph.D.; 10/1994 Molecular Biology
Her fellowships and awards include: 2002-2004: K01 DK, NIH, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Research Scientist Development Award – Research & Training 2000-2001: Harvard Medical School, Scholar in Medicine Award 1997-1999: F32 DK, NIH, National Research Service Award
Research Scientist Molecular Carcinogenesis and Chemoprevention kulp.1@osu.edu 614-292-6794
Dr. Samuel Kulp is from Wilmington, Delaware and has been with the Phelps Lab since 2018. He is driven by the goals of the Phelps Lab, and is currently working on the following projects:
Therapeutic antibody PK and efficacy in cancer cachexia