- Palmisano I*, Liu T*, Gao W, Zhou L, Merkenschlager M, Mueller F, Chadwick J, Toscano Rivalta R, Kong G, King JWD, Al-Jibury E, Yan Y, Carlino A, Collison B, De Vitis E, Gongala S, De Virgiliis F, Wang Z, Di Giovanni S. Three-dimensional chromatin mapping of sensory neurons reveals that promoter-enhancer looping is required for axonal regeneration. PNAS, 2024 September; 121(38) (co-corresponding author)
- Davis N, Taylor B, Abelleira-Hervas L, Karimian-Marnani N, Aleksynas R, Syed N, Di Giovanni S, Palmisano I, Sastre M. Histone deacetylase-3 regulates the expression of the amyloid precursor protein and its inhibition promotes neuroregenerative pathways in Alzheimer’s disease models. The FASEB Journal. 2024 May;38(10). (co-corresponding author)
- Cencioni, M. T., R. Magliozzi, Palmisano I, K. Suwan, A. Mensi, L. Fuentes-Font, L. M. Villar, J. I. Fernandez-Velasco, N. V. Migallon, L. Costa-Frossard, E. Monreal, R. Ali, M. Romozzi, N. Mazarakis, R. Reynolds, R. Nicholas, and P. A. Muraro. (2024) Soluble CD27 is an intrathecal biomarker of T-cell-mediated lesion activity in multiple sclerosis J Neuroinflammation, 21: 91.
- De Virgiliis F, Mueller F, Palmisano I, Chadwick JS, Gutierrez LLA, Giarrizzo A, Yan Y, Danzi MC, Picon-Muñoz C, Zhou L, Kong G, Serger E, Hutson TH, Maldonado-Lasuncion I, Song Y, Scheiermann C, Brancaccio M, Di Giovanni S. (2023) The circadian clock tunes axonal regenerative ability. Cell Metabolism, 5;35(12):2153-2164.
- Muller F, Chadwick JS, Di Giovanni S, Palmisano I (2023) Epigenomic Profiling of Dorsal Root Ganglia upon Regenerative and Non-regenerative Axonal Injury. Methods in molecular biology, Springer Nature book 2636:101-144.
- Zhou L, Kong G, Palmisano I, Cencioni MT, Danzi M, De Virgiliis F, Chadwick JS, Crawford G, Yu Z, De Winter F, Lemmon V, Bixby J, Puttagunta R, Verhaagen J, Pospori C, Lo Celso C, Strid J, Botto M, Di Giovanni S (2022) Reversible CD8 T cell-neuron cross-talk causes aging-dependent neuronal regenerative decline. Science 376 (6594):eabd5926.
- De Virgiliis F, Hutson T, PalmisanoI, Amachree S, Miao J, Zhou L, Todorova R, Thompson R, Danzi M, Lemmon V, Bixby JL, Wittig I, Shah AM, and Di Giovanni S. Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling. Nature Communication. 2020;11(1).
- La Montanara P, Hervera A, Baltussen LL, Hutson TH, Palmisano I, De Virgiliis F, et al. Cyclin-dependent-like kinase 5 is required for pain signaling in human sensory neurons and mouse models. Science translational medicine. 2020;12(551).
- Kong G, Zhou L, Serger E, Palmisano I, De Virgiliis F, Hutson TH, et al. AMPK controls the axonal regenerative ability of dorsal root ganglia sensory neurons after spinal cord injury. Nature metabolism. 2020;2(9):918-33.
- Palmisano I*, Danzi MC*, Hutson TH, Zhou L, McLachlan E, Serger E, et al. Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons. Nature neuroscience. 2019;22(11):1913-24. (co-corresponding author).
- Hutson TH, Kathe C, Palmisano I, Bartholdi K, Hervera A, De Virgiliis F, et al. Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models. Science translational medicine. 2019;11(487).
- Hervera A, Zhou L, Palmisano I, McLachlan E, Kong G, Hutson TH, et al. PP4-dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure. The EMBO journal.
- Palmisano I, Di Giovanni S. Advances and Limitations of Current Epigenetic Studies Investigating Mammalian Axonal Regeneration. The journal of the American Society for Experimental NeuroTherapeutics. 2018;15(3):529-40.
- Hervera A, De Virgiliis F, Palmisano I, Zhou L, Tantardini E, Kong G, et al. Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons. Nature cell biology. 2018;20(9):1098.
- De Vito A, Lazzaro M, Palmisano I, Cittaro D, Riba M, Lazarevic D, et al. Amino acid deprivation triggers a novel GCN2-independent response leading to the transcriptional reactivation of non-native DNA sequences. PloS one. 2018;13(7):e0200783.
- Wilson C, Munoz-Palma E, Henriquez DR, Palmisano I, Nunez MT, Di Giovanni S, et al. A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification. The Journal of neuroscience. 2016;36(43):11107-19.
- Palmisano I, Della Chiara G, Schiaffino MV, Poli G. Passport control for foreign integrated DNAs: An unexpected checkpoint by class II HDAC4 revealed by amino acid starvation. Mobile genetic elements. 2012;2(5):233-8.
- Palmisano I, Della Chiara G, D’Ambrosio RL, Huichalaf C, Brambilla P, Corbetta S, et al. Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4). Proceedings of the National Academy of Sciences of the United States of America. 2012;109(34):E2284-93. (Highlight in:In This Issue PNAS, 109: 13467-13468, 2012); Comment in: Jermy A. Viral infection: Coaxing HIV out of hiding. Nature Reviews Microbiology, 10: 596-7, 2012).
- Sitaram A, Piccirillo R, Palmisano I, Harper DC, Dell’Angelica EC, Schiaffino MV, et al. Localization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 function. Molecular biology of the cell. 2009;20(5):1464-77.
- Palmisano I, Bagnato P, Palmigiano A, Innamorati G, Rotondo G, Altimare D, et al. The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells. Human molecular genetics. 2008;17(22):3487-501.
- Piccirillo R, Palmisano I, Innamorati G, Bagnato P, Altimare D, Schiaffino MV. An unconventional dileucine-based motif and a novel cytosolic motif are required for the lysosomal and melanosomal targeting of OA1. Journal of cell science. 2006;119(Pt 10):2003-14.
- Innamorati G, Piccirillo R, Bagnato P, Palmisano I, Schiaffino MV. The melanosomal/lysosomal protein OA1 has properties of a G protein-coupled receptor. Pigment cell research. 2006;19(2):125-35.
- Zara V, Palmisano I, Conte L, Trumpower BL. Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b. European journal of biochemistry. 2004;271(6):1209-18.
- Zara V, Ferramosca A, Palmisano I, Palmieri F, Rassow J. Biogenesis of rat mitochondrial citrate carrier (CIC): the N-terminal presequence facilitates the solubility of the preprotein but does not act as a targeting signal. Journal of molecular biology. 2003;325(2):399-408.
- Zara V, Palmisano I, Rassow J, Palmieri F. Biogenesis of the dicarboxylate carrier (DIC): translocation across the mitochondrial outer membrane and subsequent release from the TOM channel are membrane potential-independent. Journal of molecular biology. 2001;310(5):965-71.