The Ohio Youth Resilience Collaborative (OYRC) supports counties across the state to implement evidence-based substance misuse prevention and mental health promotion programming. OYRC is a collaborative partnership with members from the College of Public Health, College of Education and Human Ecology, College of Food, Agricultural, and Environmental Sciences, Ohio State University Extension, and Central State University Extension. We work with local schools, health departments, coalitions, and community members in 15 counties to ensure that all communities have access to high quality, effective, and integrated initiatives for students and families.