Oestreich Lab Publications

Read, K. A., D. M. Jones, A. G. Freud, and K. J. Oestreich. 2021. Established and emergent roles for Ikaros transcription factors in lymphoid cell development and function. Immunol Rev 300: 82-99.

Pal, A., K. M. Gowdy, K. J. Oestreich, M. Beck, and S. R. Shaikh. 2020. Obesity-Driven Deficiencies of Specialized Pro-resolving Mediators May Drive Adverse Outcomes During SARS-CoV-2 Infection. Front Immunol 11: 1997.

Jones, D. M., K. A. Read, and K. J. Oestreich. 2020. Dynamic Roles for IL-2-STAT5 Signaling in Effector and Regulatory CD4(+) T Cell Populations. J Immunol 205: 1721- 1730.

Ringel-Scaia, V. M., M. D. Powell, K. A. Read, I. C. Allen, and K. J. Oestreich. 2019. Systemic Listeria monocytogenes Infection as a Model to Study T Helper Cell Immune Responses. Methods Mol Biol 1960: 149-160.

Ringel-Scaia, V. M., N. Beitel-White, M. F. Lorenzo, R. M. Brock, K. E. Huie, S. Coutermarsh-Ott, K. Eden, D. K. McDaniel, S. S. Verbridge, J. H. Rossmeisl, Jr., K. J. Oestreich, R. V. Davalos, and I. C. Allen. 2019. High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity. EBioMedicine 44: 112-125.

Read, K. A., M. D. Powell, B. K. Sreekumar, and K. J. Oestreich. 2019. In Vitro Differentiation of Effector CD4(+) T Helper Cell Subsets. Methods Mol Biol 1960: 75-84.

Powell, M. D., K. A. Read, B. K. Sreekumar, and K. J. Oestreich. 2019. Ikaros Zinc Finger Transcription Factors: Regulators of Cytokine Signaling Pathways and CD4(+) T Helper Cell Differentiation. Front Immunol 10: 1299.

Powell, M. D.*, K. A. Read*, B. K. Sreekumar, D. M. Jones, and K. J. Oestreich. 2019. IL-12 signaling drives the differentiation and function of a TH1-derived TFH1-like cell population. Sci Rep 9: 13991.
*these authors contributed equally to this work

Papillion, A., M. D. Powell, D. A. Chisolm, H. Bachus, M. J. Fuller, A. S. Weinmann, A. Villarino, J. J. O’Shea, B. Leon, K. J. Oestreich, and A. Ballesteros-Tato. 2019. Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-TFH cells. Sci Immunol 4.

Cesewski, E., A. P. Haring, Y. Tong, M. Singh, R. Thakur, S. Laheri, K. A. Read, M. D. Powell, K. J. Oestreich, and B. N. Johnson. 2018. Additive manufacturing of three- dimensional (3D) microfluidic-based microelectromechanical systems (MEMS) for acoustofluidic applications. Lab Chip 18: 2087-2098.

Read, K. A., M. D. Powell, C. E. Baker, B. K. Sreekumar, V. M. Ringel-Scaia, H. Bachus, R. E. Martin, I. D. Cooley, I. C. Allen, A. Ballesteros-Tato, and K. J. Oestreich. 2017. Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4(+) Th Cells. J Immunol 199: 2377-2387.

Mu, Q., H. Zhang, X. Liao, K. Lin, H. Liu, M. R. Edwards, S. A. Ahmed, R. Yuan, L. Li, T. E. Cecere, D. B. Branson, J. L. Kirby, P. Goswami, C. M. Leeth, K. A. Read, K. J. Oestreich, M. D. Vieson, C. M. Reilly, and X. M. Luo. 2017. Control of lupus nephritis by changes of gut microbiota. Microbiome 5: 73.

McDaniel, D. K., A. Jo, V. M. Ringel-Scaia, S. Coutermarsh-Ott, D. E. Rothschild, M. D. Powell, R. Zhang, T. E. Long, K. J. Oestreich, J. S. Riffle, R. M. Davis, and I. C. Allen. 2017. TIPS pentacene loaded PEO-PDLLA core-shell nanoparticles have similar cellular uptake dynamics in M1 and M2 macrophages and in corresponding in vivo microenvironments. Nanomedicine 13: 1255-1266.

McDonald, P. W., K. A. Read, C. E. Baker, A. E. Anderson, M. D. Powell, A. Ballesteros- Tato, and K. J. Oestreich. 2016. IL-7 signalling represses Bcl-6 and the TFH gene program. Nat Commun 7: 10285.

Read, K.A., M.D. Powell, and K.J. OestreichT follicular helper (TFH) cell programming by cytokine-mediated events.  Immunology. 149: 253-261 (2016). PMCID: PMC5046059.

Read, K.A., M.D. Powell, P.W. McDonald, and K.J. OestreichIL-2, IL-7, and IL-15: Multistage    regulators of CD4+ T helper cell differentiation.  Experimental Hematology. 44: 799-808 (2016). PMID: 27423815.

Cooley, I.D., K.A. Read, and K.J. OestreichTrans-presentation of IL-15 modulates STAT5 activation and Bcl-6 expression in TH1 cells.  Scientific Reports. 5: 15722 (2015). PMCID: PMC4620557.

Oestreich, K.J.*, K.A. Read, S.E. Gilbertson, K.P. Hough, P.W. McDonald, V. Krishnamoorthy, and A.S. Weinmann*.  Bcl-6 directly represses the glycolysis pathway gene program.  Nature Immunology. 15: 957-964 (2014). PMCID: PMC4226759.
*corresponding authors

Additional Selected Publications by Dr. Oestreich

Oestreich KJ, Weinmann AS. (2012). Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors. Nat Rev Immunol 12, 799-804.

Oestreich KJ, Weinmann AS. (2012). Transcriptional mechanisms that regulate T helper 1 cell differentiation. Curr Opin Immunol 24(2), 191-5.

Oestreich KJ, Mohn SE, Weinmann AS. (2012). Molecular mechanisms that control the expression and activity of Bcl-6 in Th1 cells to regulate flexibility with a Tfh-like gene profile. Nat Immunol 13(4), 405-11.

Oestreich KJ, Weinmann AS. (2012). Encoding stability versus flexibility: Lessons learned from examining epigenetics in T helper cell differentiation. Curr Top Microbiol Immunol 356, 145-64.

Oestreich KJ, Weinmann AS. (2011). T-bet employs diverse regulatory mechanisms to repress transcription. Trends Immunol 33(2), 78-83.

Youngblood B, Oestreich KJ, Ha SJ, Duraiswamy J, Akondy RS, West EE, Wei Z, Lu P, Austin JW, Riley JL, Boss JM, Ahmed R. (2011). Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity 35(3), 400-12.

Kao C, Oestreich KJ, Paley MA, Crawford A, Angelosanto JM, Ali MA, Intlekofer AM, Boss JM, Reiner SL, Weinmann AS, Wherry EJ. (2011). Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection. Nat Immunol 12(7), 633-71.

Oestreich KJ, Huang AC, Weinmann AS. (2011). The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns. J Exp Med 208(5), 1001-13.

Oestreich KJ, Yoon H, Ahmed R, Boss JM. (2008). Regulation of programmed death-1 by NFATc1 upon T cell activation. J Immunol 181(7), 4832-9.