NPASR Service List

Panels, <20 compounds Platform Examples   Sample Type
anthocyanins LC-UV-MS glycosides of cyanidin, malvidin, petunidin, peonidin, pelargonidin, delphinidin food
anthocyanins LC-UV-MS glycosides of cyanidin, malvidin, petunidin, peonidin, pelargonidin, delphinidin blood, tissue, urine
anthocyanin degradants LC-MS/MS phenolic acids, e.g. protocatechuic acid (pca) food, blood
isoflavones LC-MS/MS glucosides, malonyl glucosides, acetyl glucosides, aglycones food
isoflavone metabolites LC-MS/MS of daidzein, genistein, glycitein; equol, dihydrodaidzein, odma, dihydrogenistein blood, urine
naringenin human metabolites LC-MS/MS glucuronides, sulfates blood, urine
flavanones LC-MS/MS glycosides of naringenin, hesperetin food
flavanone microbial degradants LC-MS/MS phenolic acids urine
ellagic acid metabolites LC-MS/MS urolithin A, B, C, D, dimethyl ellagic acid, methyl UC blood, urine
flavones LC-MS/MS apigenin, luteolin, diosmetin, chrysoeriol blood, urine
flavones LC-MS/MS glycosides of apigenin, luteolin, diosmetin, chrysoeriol food
carotenoids LC beta-carotene, lutein, zeaxanthin, lycopene, cryptoxanthin, astaxanthin, neoxanthin, violaxanthin, phytoene, phytofluene food
carotenoids LC-MS/MS beta-carotene, lutein, zeaxanthin, lycopene, cryptoxanthin, astaxanthin, neoxanthin, violaxanthin, phytoene, phytofluene blood, tissue
apo-carotenoids LC-MS/MS eccentric cleavage products of lycopene, beta-carotene blood
retinoids LC-MS/MS retinoic acid, retinyl esters, retinol, retinal blood
glucosinolates LC-MS/MS glucoraphanin, glucoerucin, glucoiberin, sinigrin, glucobrassicin food
isothiocyanate (ITC) metabolites LC-MS/MS GSH, cysteinylglycinyl, cysteinyl, N-acetyl cysteinyl blood, urine
vitamin D status LC-MS/MS 25OHD2, 25OHD3 blood
vitamin D, food LC-MS/MS ergosterol, dihydro
acrylamide LC-MS/MS acrylamide with stable isotope internal standard food
linalool and metabolite LC-MS/MS linalool, linalool glucuronide food, blood, urine
soy saponins LC-MS/MS type A, B, C food
cholesterol food or in vitro digest
Panels, >20 compounds Platform Examples   Sample Type
tomato phytochemicals (>150) LC-QTOF-MS glycoalkaloids, carotenoids, phenolic acids, flavonoids, lipids food
black raspberry phytochemicals (~80) LC-QTOF-MS flavonoids, phenolic acids, ellagitannins, procyanidins, ellagic acid, ellagic acid derivatives
strawberry phytochemicals LC-QTOF-MS flavonoids, phenolic acids, ellagitannins, procyanidins, ellagic acid, ellagic acid derivatives
soy phytochemicals (in development) LC-MS/MS phytosterols, saponins, isoflavones, lipids food
burdock phenolics flavonoids plant leaves
Lipidomics Platform Examples   Sample Type
Targeted lipidomics (Lipidyzer® platform) LC-MS/MS 13 classes, >1100 lipid species blood
Untargeted Metabolomics
extraction
acquisition
feature finding
bioinformatics
Metabolic Phenotyping
isoflavones
flavanones
ellagic acid (urolithins)
ITC conjugates
Additional Information
consultation 1st hour/free, then $60/hour
method development $100/hr
technician labor $50/hr
accurate mass determination $100/sample
data analysis feature finding, pca, pls-da, venn diagram, VIP plot