2023 Meeting Presentations

  1. Benson, N.R., T.A. Wilson, G. Agarwal, E. Kaweesa, J.E. Burdette, A.D. Kinghorn, J.R. Fuchs. “Synthesis, Isolation and Structural Modification of Didesmethylrocaglamide: a Biologically Active Flavagline Natural Product with Promising Anticancer Activity.” ACS Spring 2023 Meeting, Indianapolis, IN, March 26-30, 2023. (Project 1, Core 1, Core 2).
  2. Mize, B., A. Huntsman, A. Salvi, C. Takaoka, J.R. Fuchs, J.E. Burdette. “Methods of D-ring Synthesis for Optimization of the Phyllanthusmin Class of Natural Product against Ovarian Cancer.” ACS Spring 2023 Meeting, Indianapolis, IN, March 26-30, 2023. (Core 1, Core 2).
  3. Alexander, K., I.M. Chauvin, A.S. Eustaquio, J.E. Orjala. “Efficient DNA Extraction Methods of Filamentous Cyanobacteria for Genome-driven Drug Discovery.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 2).
  4. Al-Qiam, R.A., F.S.T. Khan, M. Rangel-Grimaldo, H.A. Raja, C.J. Pearce, S. Hematian, N.H. Oberlies. “Increased Conversion of Hypocrellins to Hypomycins Under Anaerobic Growth Conditions.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3).
  5. Castro-Dionicio, I.I., E.D. Salinas-Arellano, E.J. Carcache de Blanco. “LC-MS/MS-based Dereplication of Cytotoxic Compounds in Two Extracts from the NCI Natural Products Repository.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Supplement P01CA125066-14S1).
  6. Chauvin, I.M., K. Alexander, J. Orjala. “Genetics-guided Dereplication of Crytophycin Analogues and Bioactive Peptides in Cyanobacteria.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 2).
  7. Earp, C., A. Clements, A. Lee, R. Gupta, N. Ayon, F. Butun, D. Dainko, M. Robey, M. Khin, J.E. Burdette, J.W. Bok, N.P. Keller, A. Longcake, M.J. Hall, M.R. Probert, H.A. Raja, N.H. Oberlies, N.L. Kelleher, and L.K. Caesar. “Use of Biosynthetic Gene Clusters to Identify Stemphone Analogues.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3, Core 1).
  8. El-Elimat, T., R. Al-Qiam, A.H. Al Sharie, M. Al-Gharaibeh, M. Khin, J.E. Burdette, N.H. Oberlies. “Homoisoflavonoids with Cytotoxic Activity from the Bulbs of Bellevalia desertorum.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3, Core 1).
  9. El-Elimat, T., T. Cameron, P. Gürbüz, H.A. Rafa, M. Khin, J.E. Burdette, N.H. Oberlies. “A 8,8′-Binaphthopyranone and Xylarenones with Cytotoxic Activity from a Freshwater Fungus.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3, Core 1).
  10. El-Elimat, T., R.T. Munaiem, R. Al-Qiam, M. Al-Gharaibeh, L. Fakhouri, A.H. Al Sharie, M. Khin, J.E. Burdette, N.H. Oberlies. “Cytotoxic Colchicinoids from Colchicum tuviae Feinbrun (Colchicaceae).” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3, Core 1).
  11. Ezzone, N., P.J. Blanco Carcache, T.N. Ninh, E. Mekuria Addo, E.D. Salinas-Arellano, D.D. Soejarto, A.D. Kinghorn. “Isolation of Cytotoxic Phytochemicals from Aralia vietnamensis.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 1, Project 2).
  12. Ezzone, N., I.I. Castro-Dionicio, E.D. Salinas-Arellano, A.D. Kinghorn, E.J. Carcache de Blanco. “Identification and Isolation of Potential Anticancer Agents from a Penicillium sp.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 1, Supplement P01CA125066-14S1).
  13. Jeyaraj, J.G., I. Castro-Dionicio, E.D. Salinas-Arellano, A.D. Kinghorn, E.J. Carcache de Blanco. “Molecular Networking-driven Discovery of Potent Cytotoxic Natural Products from an Aspergillus sp. (Trichocomiaceae).” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Supplement P01CA215066-14S1).
  14. Kaweesa, E.N., J.M. Bazioli, H.C. Pierre, D.D. Lantvit, S.K. Kulp, K.L. Hill, M.A. Phelps, C.C. Coss, J.R. Fuchs, C.J. Pearce, N.H. Oberlies, J.B. Burdette. “Verticillin Cytotoxic Activity in High Grade Serous Ovarian Cancer in Preclinical in Vitro and in Vivo Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3, Core 1, Core 2).
  15. Khin, M., M. Rangel-Grimaldo, H.A. Raja, Z. Zhang, J. Ekiert, N.H. Oberlies, Y. Gao, J.E. Burdette. “Wheldone, a Fungal Secondary Metabolite Deregulates HNRNPD, a DNA Repair Protein.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3, Core 1).
  16. Lindsay, C.A., C.Y. Tan, G. Anaya-Eugenio, C.A. Rappleye, R.W. Spjut, E.J. Carcache de Blanco, A.D. Kinghorn, H.L. Rakotondraibe. “Investigation of Precursor-derived Secondary Metabolites of Penicillium arauntiacobrunneum for Potential Cytotoxic Activity.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 1).
  17. Mekuria Addo, E., M. Khin, D. Uchenik, R.W. Spujt, J.E. Burdette, A.D. Kinghorn, H.L. Rakotondraibe. “Dereplication and Isolation of Secondary Metabolites from the Two Selected Lichens Mobergia calculiformis and Niebla joseuervoi.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 1, Core 1).
  18. Meyer, G., P. Shriwas, T. Frank, K. DeRose, J. Lei, J.R. Grebenc, R. Slaughter, G. Gao, X. Chen, A.D. Kinghorn, Y. Ren. “Glucose Transport Inhibition and Cancer Cell Cytotoxicity of the Fruits of Aronia melanocarpa.”  Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 1).
  19. Pierre, H.C., Z.Y. Al-Subeh, R.H. Bockbrader, R.J. Tokarskii II, A.C. Maldonado, M. Haughan, M., M.E. Rangel Grimaldo, C.J. Pearce, J.E. Burdette, J.R. Fuchs, N.H. Oberlies. “Development of First-Generation Eupenifeldin Semi-Synthetic Analogues via Hydroxy Group Modifications.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023 (Project 3, Core 1).
  20. Pierre, H.C., D. Patel, H.A. Raja, E.A. Darveaux, K. Patel, L. Mardiana, A. Longcake, M.J. Hall, M. Probert, C.J. Pearce, N.H. Oberlies. “Verticillin D: Media Studies, Streamlined Purification, and Absolute Configuration.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3).
  21. Pourhadi, H., T. El-Elimat, M. Rangel-Grimaldo, T.N. Graf, J.O. Falkinham III, M. Khin, J.E. Burdette, C.J. Pearce, N.H. Oberlies. “Fluorination of Diepoxin-η: Characterization and Anticancer Activity Evaluation of Semisynthetic Derivatives of Spirobisnaphthalenes.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3, Core 1).
  22. Rangel-Grimaldo, M., H.A. Raja, N.H. Oberlies. “Improving the Production of Wheldone, a Secondary Metabolite Produced by a Co-Culture of Xylaria flabelliformis and Aspergillus fischeri.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 3).
  23. Ren, Y., E.N. Kaweesa, L. Tian, S. Wu, K. Sydara, M. Xayvue, C.E. Moore, D.D. Soejarto, X. Cheng, J. Yu, J.E. Burdette, A.D. Kinghorn. “The Cytotoxic Cardiac Glycoside (-)-Cryptanoside A Isolated from the Stems of Cryptolepis dubia Collected in Laos.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 1, Project 2, Core 1).
  24. Ren, Y., A. McMaster, L. Li, K. DeRose, E.N. Kaweesa, K. Sydara, M. Xayvue, P. Pandey, A.G. Chittiboyna, Z. Ali, J.C. Gallucci, D. Ferreira, D.D. Soejarto, J.E. Burdette, A.D. Kinghorn. “Cytotoxic Leuconoxine-type Diazaspeiroindole Alkaloid Isolated from Cryptolepis dubia and its Analogues.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 1, Project 2, Core 1).
  25. Salinas-Arellano, E.D., I.I. Castro-Dionicio, E.J. Carcache de Blanco. “Bioassay-guided Study of Pyrenacantha kaurabassana from the NCI Natural Products Repository.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Supplement P01CA125066-14S1).
  26. Salinas-Arellano, E.D., I.I. Castro-Dionicio, E.J. Carcache de Blanco. “Bioassay-guided Study and Molecular Networking of Curessus arizonica from the NCI-NPR.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Supplement P01CA125066-14S1).
  27. Terrasson, K., E. Mekuria Addo, M. Khin, B. Kirkpatrick, A. Maldonado, T.N. Ninh, H.L. Rakotondraibe, J.E. Burdette, D.D. Soejarto, A.D. Kinghorn. “New and Bioactive Compounds from the Branches of the Vietnam Plant Beilschiedia yunnanensis.” Annual Meeting of the American Society of Pharmacognosy, Rockville, MD, July 22-26, 2023. (Project 1, Project 2, Core 1).