2022 Publications

    1. Salvi A, Young AN, Huntsman AC, Pergande MR, Korkmaz MA, Rathnayake RA, Mize BK, Kinghorn AD, Zhang X, Ratia K, Schrile M, Thomas JR, Brittain SM, Shelton C, Aldrich LN, Cologna SM, Fuchs JR, Burdette JE. PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer. Cell Death Dis. 2021 Jan 10:13(1):45. E-pub 2022 Jan 10. PMCID: PMC8748433.
    1. Lu C, Yang D, Klement JD, Colson YL, Oberlies NH, Pearce CJ, Colby AH, Grinstaff MW, Ding HF, Shi H, Liu K. G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes. J Immunother Cancer 2022 Jan;10(1):e003543. E-Pub 2022 Jan 11. PMCID: PMC8753452.
    2. Flores-Bocanegra L, Al Subeh ZY, Egan JM, El-Elimat T, Rafa HA, Burdette JE, Pearce CJ, Linington RG, Oberlies NH. Dereplication of fungal metabolites by NMR-based compound networking using MADByTE. J Nat Prod. 2022 Mar; 85(3):614-624. E-pub 2022 Jan 12. PMCID: PMC8957573. (Special issue in honor of Dr. William H. Gerwick).
    3. Al Subeh ZY, Waldbusser AL, Raja HA, Pearce CJ, Ho KL, Hall MJ, Probert MR, Oberlies NH, Hematian S. Structural diversity of perylenequinones is driven by their redox behavior. J Org Chem. 2022 Mar 4;87(5):2697-2710. E-pub 2022, Jan. 25. PMCID: PMC8898278.
    4. Davis L, Maldonado AC, Khin M, Krunic A, Burdette JE, Orjala J. Aulosirazoles B and C from the Cyanobacterium Nostoc sp. UIC 10771: Analogues of an isothiazolonaphthoquinone scaffold that activate nuclear transcription factor FOXO3a in ovarian cancer cells. J Nat Prod. 2022 Mar; 85(3): 540-546. E-pub 2022 Jan 31. PMCID: PMC8957594. (Special issue in honor of Dr. William H. Gerwick).
    1. Gubiani JR, Bernardi DI, De Paula CCP, Seleghim MHR, Ferreira AG, Batista ANL, Batista JM Jr, Oliveira LFP, Lira SP, Burdette JE, Berlinck RGS. Absolute configuration of cytotoxic anthraquinones from a Brazilian cave soil-derived fungus, Aspergillus sp. SDC28. Arch. Pharm. 2022 Apr;355(4):e2100441. E-pub 2022 Jan 31. PMCID: PMC8983557.
    2. Yamano Y, Rakotondraibe HL. Understanding the biosynthesis of paxisterol in lichen-derived Penicillium aurantiacobrunneum for production of fluorinated derivatives. Molecules 2022 Mar 2; 27(5):1641. E-pub 2022 Mar 2. PMCID: PMC8911623.
    3. Lu C, Yang D, Klement JD, Colson YL, Oberlies NH, Pearce CJ, Colby AH, Grinstaff MW, Liu Z, Shi H, Ding HF, Liu K. H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth. Oncogene 2022 Apr; 41(18):2651-2662. E-pub 2022 Mar 30. PMCID: PMC9058223.
    4. Cank KB, Shepherd RA, Knowles SL, Rangel-Grimaldo M, Raja HA, Bunch ZL, Cech NB, Rice CA, Kyle DE, Falkinham III JO, Burdette JE, Oberlies NH. Polychlorinated cyclopentenes from a marine derived Periconiasp. (strain G1144). Phytochemistry 2022 Jul;199:113200. E-pub 2022 Apr 11. PMCID: PMC9173697.
    5. Freire VF, Gubiani JR, Spencer TM, Hajdu E, Ferreira G, Ferreira DAS, de Castro Levatti EV, Burdette JE, Camargo CH, Tempone AG, Berlinck RGS. Feature-based molecular networking discovery of bromopyrrole alkaloids from the marine sponge Agelas dispar. J Nat Prod. 2022 May 27;85(5):1340-1350. E-pub 2022 Apr 15. PMCID: PMC9680911.
    6. Al Subeh ZY, Li T, Ustoyev A, Obike JC, West PM, Khin M, Burdette JE, Pearce CJ, Oberlies NH, Croatt MP. Semisynthesis of hypothemycin analogues targeting the C8−C9 diol. J Nat Prod. 2022 Aug 26;85(8):2018-2025. E-pub 2022 Jul 14. PMCID: PMC9677340.
    7. Blanco Carcache, PJ, Anaya-Eugenio GD, Ninh YN, Moore CE, Rivera-Chávez J, Ren Y, Soejarto DD, Kinghorn AD. Cytotoxic constituents of Glycosmis ovoidea collected in Vietnam. Fitoterapia 2022 Oct;162:105265. E-pub 2022 Aug 10. PMCID: PMC9532375.
    8. El-Elimat T, Al-Qiam R, Burdette JE, Al Sharie AH, Al-Garaibeh M, Oberlies NH. Homoisoflavonoids from the bulbs of Bellevalia longipesand an assessment of their potential cytotoxic activity. Phytochemistry 2022 Nov;203:113343. E-pub 2022 Aug 11. PMCID: PMC9795560.
    9. Mirtallo Ezzone NP, Anaya-Eugenio GD, Addo EM, Ren Y, Kinghorn AD, Carcache de Blanco EJ. Effects of cochorususoside C on NF-kB and PARP-1 molecular targets and toxicity profile in zebrafish. Int. J. Mol. Sci. 2022 Nov 22;23(23):14546. E-pub 2022 Nov. 22. PMCID: PMC9739208.