2020 Publications

  1. Salvi, A., C.S.M. Amrine, J.R. Austin, K. Kilpatrick, A. Risso, D Lantvit, E. Calderon-Gierszal, Z. Mattes, C.J. Pearce, M.W. Grinstaff, A.H. Colby, N.H. Oberlies, and J.E. Burdette. 2020. Verticillin A causes apoptosis and reduced tumor burden in high grade serous ovarian cancer by inducing DNA damage. Mol. Cancer Ther. 19:89-100. (PMCID: PMC6951445).
  2. Kao, D., L. Flores-Bocanegra, H.A. Raja, B.A. Darveaux, C.J. Pearce, and N.H. Oberlies. 2020. New dogs for old tricks: Two new macrocyclic trichothecene epimers and absolute configuration of 16-hydroxyverrucarin B. Phytochemistry 172:112238. (PMCID: PMC7050405).
  3. Ren, Y., Q. Tan, K. Heath, S. Wu, J.R. Wilson, J. Ren, P. Shriwas, C. Yuan, T.N. Ninh, H.-B. Chai, X. Chen, D.D. Soejarto, M.E. Johnson, J.B. Burdette, and A.D. Kinghorn. 2020. Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper. Bioorg. Med. Chem. 28:115301. (PMCID: PMC7029422).
  4. Chang, L.-S., J.L. Oblinger, S.S. Burns, J. Huang, L.W. Anderson, M.G. Hollingshead, R. Shen, L. Pan, G. Agarwal, Y. Ren, R. Roberts, B.R. O’Keefe, A.D. Kinghorn, and J.M. Collins. 2020. Targeting protein translation by rocaglamide and didesmethylrocaglamide to treat MPNST and other sarcomas. Mol. Cancer Ther. 19:731-741. (PMCID: PMC7056570).
  5. Ren, Y., H.T. Ribas, K. Heath, S. Wu., J. Ren, P. Shriwas, X. Chen, M.E. Johnson, X. Cheng, J.E. Burdette, and A.D. Kinghorn. 2020. Na+/K+-ATPase-targeted cytotoxicity of (+)-digoxin and several semi-synthetic derivatives. J. Nat. Prod. 83:638-648. (Special issue in honor of Dr. J. Clardy). (PMCID: PMC7243443).
  6. Knowles, S.L., H.A. Raja, I.H. Isawi, L. Flores-Bocanegra, P.H. Reggio, C.J. Pearce, J.E. Burdette, A. Rokas, and N.H. Oberlies. 2020. Wheldone: Characterization of a unique scaffold from the coculture of Aspergillus fischeri and Xylaria flabelliformis. Org. Lett. 22:1878-1882. (PMCID: PMC7153779).
  7. Crnkovic, C.M., J. Braesel, A. Krunic, A.S. Eustáquio, and J. Orjala. 2020.Scytodecamide from the cultured Scytonema sp. UIC 10036 expands the chemical and genetic diversity of cyanobactins. ChemBioChem. 21:845-852. (PMCID: PMC7078034).
  8. May, D.S., C.M. Crnkovic, T.A. Wilson, J.R. Fuchs, and J.E. Orjala. 2020. 15N Stable isotope labeling and comparative metabolomics facilitates genome mining in cultured cyanobacteria. ACS Chem Biol. 15:758-765. (PMCID: PMC7297037).
  9. Sullivan, P, A. Krunic, J.E. Burdette, and J. Orjala. 2020. Laxaphycin B5 and B6 from the cultured cyanobacterium cf. Phormidium sp. UIC 10484. J Antibiot. 73:526-533. (Special issue in honor of Dr. W. Fenical). (PMCID: PMC7338234).
  10. Anaya-Eugenio, G.D., C.Y. Tan, H.L. Rakotondraibe, and E. J. Carcache de Blanco. 2020. Tumor suppressor p53 independent apoptosis in HT-29 cells by auransterol from Penicillium aurantiacobrunneum. Biomed. Pharmacother. 127:110124. (PMCID: PMC7584345).
  11. Al Subeh, Z.Y., H.A. Raja, S. Monro, L. Flores-Bocanegra, T. El-Elimat, C.J. Pearce, S.A. McFarland, and N.H. Oberlies. 2020. Enhanced production and anticancer properties of photoactivated perylenequinones. J. Nat. Prod. 83:2490-2500. (Erratum 2020 J. Nat. Prod. 83: 3765-3766). (PMCID: PMC7493285).
  12. Li, S., S.A. Newmister, A.N. Lowell, J. Zi, C.R. Chappell, F. Yu, J. Orjala, R.M. Williams, and D.H. Sherman. 2020. Control of stereoselectivity in diverse hapalindole metabolites is mediated by cofactor induced combinatorial pairing of Stig cyclases. Angew. Chem. Int. Ed. Engl. 59:8166-8172. (PMCID: PMC7274885).
  13. Zhang, Y., C.Y. Tan, R.W. Spjut, A.D. Kinghorn, and LH. Rakotondraibe. 2020. Specialized metabolites of the United States lichen Niebla homalea and their antiproliferative activity. Phytochemistry 180: 112521. (PMCID: PMC7970382).
  14. El-Alimat T, M.B. Alhawarri, J. Rivera-Chávez, J.E. Burdette, A. Czarnecki, M. Al-Gharaibeh, A.H. Al Sharie, A. Alhusban, F.Q. Alali, and N.H. Oberlies. 2020. Phenethylisoquinoline alkaloids from the leaves of Androcymbium palaestinum. Fitoterapia 146:104706. (PMCID: PMC7871506).
  15. Anaya-Eugenio, G.D., N.A. Eggers, Y. Ren, J.A. Rivera-Chávez, A.D. Kinghorn, and E.J. Carcache de Blanco. 2020. Apoptosis induced by (+)-betulin through NF-kB inhibition in MDA-MB-321 breast cancer cells. Anticancer Res. 40:6637-6647. (PMCID: PMC7849021).
  16. Rokas, A., M.E. Mead, J.L. Steenwyk, N.H. Oberlies, and G.H. Goldman. 2020. Evolving moldy murderers: Aspergillus section Fumigati as a model for studying the repeated evolution of fungal pathogenicity. PLoS Pathog. 16:e1008315. (PMCID: PMC7046185).
  17. Steenwyk, J.L., M.E. Mead, S.L. Knowles, H.A. Raja, C.D. Roberts, O. Bader, J. Houbraken, G.H. Goldman, N.H. Oberlies, and A Rokas. 2020. Variation among biosynthetic gene clusters, secondary metabolite profiles, and cards of virulence across Aspergillus species. Genetics 216:481-497. (PMCID: PMC7536862)
  18. Guo, B., M. Zhao, Z. Wu, M.M. Onakpa, J.E. Burdette, and C.-t. Che. 2020. 19-Nor-pimaranes from Icania trichantha. Fitoterapia 146:104612. (Erratum 2020 Fitoterapia 146: 104656). (PMCID: PMC7374768).