2020 Publications

  1. Salvi A, Amrine CSM, Austin SM, Kilpatrick K, Russo A, Lantvit D, Calderon-Gierszal E, Mattes Z, Pearce CJ, Grinstaff MW, Colby AH, Oberlies NH, Burdette JE. Verticillin A causes apoptosis and reduced tumor burden in high-grade serous ovarian cancer by inducing DNA damage. Mol Cancer Ther. 2020 Jan; 19(1):89-100. Epub 2020 Jan 3. PMCID: PMC6951445.
  2. Kao D, Flores-Bocanegra L, Raja HA, Darveaux BA, Pearce CJ, Oberlies NH. New dogs for old tricks: Two new macrocyclic trichothecene epimers and absolute configuration of 16-hydroxyverrucarin B. Phytochemistry 2020 Apr; 172(1): art. no. 112238. Epub 2020 Jan 10. PMCID:PMC7050405.
  3. Ren Y, Tan Q, Heath K, Wu S, Wilson JR, Ren J, Shriwas P, Yuan C, Ninh TN, Chai H-B, Chen X, Soejarto DD, Johnson ME, Burdette JE, Kinghorn AD. Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper. Bioorg. Med. Chem. 2020 Feb 15; 28(4): art. no. 115301. Epub 2000 Jan 7. PMCID: PMC7029422.
  4. Chang L-S, Oblinger JL, Burns SS, Huang J, Anderson LW, Hollingshead MG, Shen R, Pan L, Agarwal G, Ren Y, Roberts R, O’Keefe BR, Kinghorn AD, Collins JM. Targeting protein translation by rocaglamide and didesmethylrocaglamide to treat MPNST and other sarcomas. Mol Cancer Ther. 2020 Mar; 19:731-741. Epub 2019 Dec 17. PMCID – PMC7056570.
  5. Knowles SL, Raja HA, Isawi IH, Flores-Bocanegra L, Reggio PH, Pearce CJ, Burdette JE, Rokas A, Oberlies NH. Wheldone: Characterization of a unique scaffold from the coculture of Aspergillus fischeri and Xylaria flabelliformis. Org Lett. 2020 Mar 6; 22(5):1878-1882. Epub 2020 Feb 25. PMCID:PMC7153779.
  6. Ren,Y, Ribas HT, Heath K, Wu S, Ren J, Shriwas P, Chen X, Johnson ME, Cheng X, Burdette JE, Kinghorn AD. Na+/K+-ATPase-targeted cytotoxicity of (+)-digoxin and several semi-synthetic derivatives. J Nat Prod. 2020 Mar; 83(3):638-648. Epub 2020 Feb 25.  PMCID:PMC7243443. (Special issue in honor of Dr. J. Clardy).
  7. Crnkovic CM, Braesel J, Krunic A, Eustáquio AS, Orjala J. Scytodecamide from the cultured Scytonema UIC 10036 expands the chemical and genetic diversity of cyanobactins. ChemBioChem. 2020 Mar 16; 21(6), 845-852. E-pub 2019 Nov 26. PMCID:PMC707803.
  8. May DS, Crnkovic CM, Wilson TA, Fuchs JR, Orjala JE. 15N Stable isotope labeling and comparative metabolomics facilitates genome mining in cultured cyanobacteria. ACS Chem Biol.2020 Mar; 15(3):758-765. Epub 2020 Mar 9. (PMCID: PMC7297037).
  9. Sullivan P, Krunic A, Burdette JE, Orjala J. Laxaphycin B5 and B6 from the cultured cyanobacterium cf. Phormidium UIC 10484. J Antibiot. 2020 Aug; 73(8):526-533. Epub 2020 Mar 31. (Special issue in honor of Dr. W. Fenical). (PMCID: PMC7338234).
  10. Anaya-Eugenio GD, Tan CY, Rakotondraibe HL, Carcache de Blanco EJ. Tumor suppressor p53 independent apoptosis in HT-29 cells by auransterol from Penicillium aurantiacobrunneum. Biomed Pharmacother. 2020 Jul; 127: art. no. 110124. (PMCID: PMC7584345).
  11. Al Subeh ZY, Raja HA, Monro S, Flores-Bocanegra L, El-Elimat T, Pearce CJ, McFarland SA, Oberlies NH. Enhanced production and anticancer properties of photoactivated perylenequinones. J Nat Prod. 2020 Aug; 83(8):2490-2500. Epub 2020 Aug 10; erratum J Nat Prod. 83 (12):3765-3766. Epub 2020 Dec 14. (PMCID: 7493285).
  12. Li S., Newmister SA, Lowell AN, Zi J, Chappell CR, Yu F, Orjala J, Williams RM, Sherman DH. Control of stereoselectivity in diverse hapalindole metabolites is mediated by cofactor induced combinatorial pairing of Stig cyclases. Angew Chem Int Ed Engl. 2020 May 18; 59(21):8166-8172. Epub 2020 Mar 19. (PMCID: 7274885).
  13. Zhang Y, Tan CY, Spjut RW, Fuchs, JR, Kinghorn AD, Rakotondraibe LH. Specialized metabolites of the United States lichen Niebla homalea and their antiproliferative activity. Phytochemistry. 2020 Dec; 180, art. no. 112521. Epub 2020 Oct 21. (NIHMSID: 1633785; PMCID – in process).
  14. El-Alimat T, Alhawarri MB, Rivera-Chávez J, Burdette JE, Czarnecki A, Al-Gharaibeh M, Al Sharie AH, Alhusban A. Alali FQ, Oberlies NH. Phenethylisoquinoline alkaloids from the leaves of Androcymbium palaestinum. 2020 Oct; 146: art. no. 104706. Epub 2020 Aug 21. (NIHMSID: 1664778; PMCID – in process).
  15. Anaya-Eugenio GD, Eggers NA, Ren Y, Rivera-Chávez JA, Kinghorn AD, Carcache de Blanco EJ. Apoptosis induced by (+)-betulin through NF-kB inhibition in MDA-MB-321 breast cancer cells. Anticancer Res. 2020 Dec; 40(12):6637-6647. Epub 2020 Dec 7. (PMCID: PMC7849021).
  16. Guo B, Zhao M, Wu Z, Onakpa MM, Burdette JE, Che C-t. 19-Nor-pimaranes from Icania trichantha. Fitoterapia 2020 Jul; 146: art. no. 104612. Epub 2020 May 11. Erratum Fitoterapia 2020 Oct; 146: art. no. 104656. Epub 2020 Jun 23. (PMCID: PMC7384768).