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- Salim, A.A., A.D. Pawlus, H.-B. Chai, N.R. Farnsworth, A.D. Kinghorn, and E.J. Carcache-Blanco. 2007. Ponapensin, a cyclopenta[b,c]benzopyran with potent NF-κB inhibitory activity from Aglaia ponapensis. Bioorg. Med. Chem. Lett. 17:109-112. (PMCID: PMC2786496).
- Jones, W.P., T. Lobo-Echeverri, Q. Mi, H.-B. Chai, D.D. Soejarto, G.A. Cordell, S.M. Swanson, and A.D. Kinghorn. 2007. Cytotoxic constituents from the fruiting branches of Callicarpa americana collected in southern Florida. J. Nat. Prod. 70:372-377. (PMCID: PMC2447917). (Special issue dedicated to the late Dr. Kenneth L. Rinehart).
- Salim, A.A., B.-N. Su, H.-B. Chai, S. Riswan, L.B.S. Kardono, A. Ruskardi, N.R. Farnsworth, S.M. Swanson, and A.D. Kinghorn. 2007. Dioxadispiroketal compounds and a potential acyclic precursor from Amomum aculeatum. Tetrahedron Lett. 48:1849-1853. (PMCID: PMC1950142).
- Phifer, S.S., D. Lee, E.-K. Seo, N.-C. Kim, T.N. Graf, D.J. Kroll, H.A. Navarro, R.A. Izydone, F. Jiménez, R. García, W.C. Rose, C.R. Fairchild, R. Wild, D.D. Soejarto, N.R. Farnsworth, A.D. Kinghorn, N.H. Oberlies, M.E. Wall, and M.C. Wani. 2007. Alvaradoins E-N, new antitumor and cytotoxic anthracenone C-glycosides from the leaves of Alvaradoa haitensis. J. Nat. Prod. 70:954-961. (PMCID: PMC2442713).
- Kim, S., B.Y. Hwang, B.-N. Su, H. Chai, Q. Mi, A.D. Kinghorn, R. Wild, and S.M. Swanson. 2007. Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosomal pathway without activation of executioner caspase-3 or -7. Anticancer Res. 27:2175-2184. (PMCID: PMC2787233).
- Salim, A.A., H.-B. Chai, I. Rachman, S. Riswan, L.B.S. Kardono, N.R. Farnsworth, E.J. Carcache-Blanco, and A.D. Kinghorn. 2007. Constituents of the leaves and stem bark of Aglaia foveolata. Tetrahedron 63:7926-7984. (PMCID: PMC2034361).
- Chin, Y.-W., A.D. Kinghorn, and P. Patil. 2007. Evaluation of the cholinergic and adrenergic effects of two tropane alkaloids from Erythroxylum pervillei. Phytother. Res. 21:1002-1005. (PMCID: PMC2798816).
- Chin, Y.-W., A.A. Salim, B.-N. Su, Q. Mi, H.-B. Chai, S. Riswan, L.B.S. Kardono, A. Ruskandi, N.R. Farnsworth, S.M. Swanson, and A.D. Kinghorn. 2008. Potential anticancer activity of naturally occurring and semi-synthetic derivatives of aculeatins A and B from Amomum aculeatum. J. Nat. Prod. 71:390-395. (Included in a special issue dedicated to Dr. G. Robert Pettit). (PMCID: PMC2518721).
- Pan, L., Y.-W. Chin, H.-B. Chai, T.N. Ninh, D.D. Soejarto, and A.D. Kinghorn. 2009. Activity-guided solation of cytotoxic constituents of Brucea javanica collected in Vietnam. Bioorg. Med. Chem. 17:2219-2224. (Included in a “Symposium in Print” entitled “Medicinal Chemistry of Natural Products”, edited by G.M. Cragg and D.J. Newman, National Cancer Institute, Frederick, MD). (PMCID: PMC2683946). (Erratum Bioorg. Med. Chem. 19:1562, 2011. PMCID: PMC3072587).
- Lucas, D.M., R.B. Edwards, G. Lozanski, D.A. West, J.D. Shin, M.A. Vargo, M.E. Davis, D.E. Rozewski, A.J. Johnson, B.-N. Su, V.M. Goettl, N.A. Heerema, T.S. Lin, A. Lehman, X. Zhang, D. Jarjoura, D.J. Newman, J.C. Byrd, A.D. Kinghorn, and M.R. Grever. 2009. The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo. Blood 113:4656-4666. (PMCID: PMC2680369).
- Deng, Y., M.J. Balunas, J.-H. Kim. D.D. Lantvit, Y.-W. Chin, H. Chai, S. Sugiarso, L.B.S. Kardono, H.H.S. Fong, J.M. Pezzuto, S.M. Pezzuto, E.J. Carcarche de Blanco, and A.D. Kinghorn. 2009. Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. Nat. Prod. 72:1165-1169. (PMCID: PMC2883770).
- Li, C, D. Lee, T.N. Graf, S.S. Phifer, Y. Najanishi, S. Riswan, F.M. Setyowati, A.M. Saribi, D.D. Soejarto, N.R. Farnsworth, J.O. Falkingham III, D.J. Kroll, A.D. Kinghorn, M.C. Wani, and N.H. Oberlies. 2009. Bioactive constituents of the stem bark of Mitrephora glabra. J. Nat. Prod. 72:1949-1953. (PMCID: PMC2862477).
- Han, A.-R., J.-A. Kim, D.D. Lantvit, L.B.S. Kardono, S. Riswan, H. Chai, E.J. Carcache de Blanco, N.R. Farnsworth, S.M. Swanson, and A.D. Kinghorn. 2009. Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (Mangosteen). J. Nat. Prod. 72:2028-2032. (PMCID: PMC2887388).
- Pan, L., D.D. Lantvit, S. Riswan, L.B.S. Kardono, H. Chai, E.J. Carcache de Blanco, N.R. Farnsworth, D.D. Soejarto, S.M. Swanson, and A.D. Kinghorn. 2010. Bioactivity-guided isolation of cytotoxic sesquiterpenes of Rolandra fruticosa. Phytochemistry 71:635-640. (PMCID: PMC2847506).
- Ren, Y., L.B.S. Kardono, S. Riswan, H. Chai, N.R. Farnsworth, D.D. Soejarto, E.J. Carcache de Blanco, and A.D. Kinghorn. 2010. Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida. J. Nat. Prod. 73:949-955. (PMCID: PMC2878397).
- Ren, Y., D.D. Lantvit, E.J. Carcache de Blanco, L.B.S. Kardono, S. Riswan, H. Chai, C.E. Cottrell, N.R. Farnsworth, S.M. Swanson, Y. Ding, X.-C. Li, J.P.J. Marais, D. Ferreira, and A.D. Kinghorn. 2010. Proteasome-inhibitory and cytotoxic constituents of Garcinia lateriflora: absolute configuration of caged xanthones. Tetrahedron 66:5311-5320. (PMCID: PMC2923493).
- Sy-Cordero, A., T.N. Graf, M.C. Wani, D.J. Kroll, C.J. Pearce, and N.H. Oberlies. 2010. Dereplication of macrocyclic trichothecenes from extracts of filamentous fungi through UV and NMR profiles. J. Antibiot. 63:539-544. (PMCID: PMC2946446).
- Kim, J.-A., E.K. Lau, L. Pan, and E.J. Carcache de Blanco. 2010. NF-kappaB inhibitors from Brucea javanica exhibiting intracellular effects on reactive oxygen species. Anticancer Res. 30: 3295-3300. (PMCID: PMC3013507).
- Chlipala, G.E., M. Sturdy, A. Krunic, D.D. Lantvit, Q. Shen, K. Porter, S.M. Swanson, and J. Orjala. 2010. Cylindrocyclophanes with proteasome inhibitory activity from the cyanobacterium Nostoc sp. J. Nat. Prod. 73:1529-1537. (PMCID: PMC2964865).
- Pan, L., L.B.S. Kardono, S. Riswan, H. Chai, E.J. Carcache de Blanco, C.M. Pannell, D.D. Soejarto, T.G. McCloud, D.J. Newman, and A.D. Kinghorn. 2010. Isolation and characterization of minor analogues of silvestrol and other constituents from a large-scale recollection of Aglaia foveolata. J. Nat. Prod. 73:1873-1878. (PMCID: PMC2993763).
- Krunic, A., A. Vallat, S. Mo, D.D. Lantvit, S.M. Swanson, and J. Orjala. 2010. Scytonemides A and B, peptides with 20S proteasome inhibitory activity from the cultured cyanobacterium Scytonema hofmanii. J. Nat. Prod. 73:1927-1932. (PMCID: PMC3074188).
- Mo, S., A. Krunic, B. Santarsiero, S.G. Franzblau, and J. Orjala. 2010. Hapalindole-related alkaloids from the cultured cyanobacteria Fischerella ambigua, Phytochemistry 71:2116–2123. (PMCID: PMC2981615).
- Ren, Y., C.-H. Yuan, H.-B. Chai, Y.-Q. Ding, X.-C. Li, D. Ferreira, and A.D. Kinghorn. 2011. Absolute configuration of (-)-gambogic acid, an antitumor agent. J. Nat. Prod. 74:460-463. (Included in a special issue dedicated to Dr. Koji Nakanishi). (PMCID: PMC3052414).
- Ren, Y., S. Matthew, D.D. Lantvit, T.N. Ninh, H. Chai, J.R. Fuchs, D.D. Soejarto, E.J. Carcache de Blanco, S.M. Swanson, and A.D. Kinghorn. 2011. Bioactive constituents of the stems of Cratoxylum cochinchinense and some semi-synthetic analogues. J. Nat. Prod. 74:1117-1125. (PMCID: PMC3103643).
- Ayers, D., T.N. Graf, A.F. Adcock, D.J. Kroll, S. Matthew, E.J. Carcache de Blanco, Q. Shen, S.M. Swanson, M.C. Wani, C.J. Pearce, and N.H. Oberlies. 2011. Resorcylic acid lactones with cytotoxic and NF-kappaB inhibitory activities and their structure-activity relationships. J. Nat. Prod. 74:1126-1131. (PMCID: PMC3111092).
- Chlipala, G. E., A. Krunic, S. Mo, M. Sturdy, and J. Orjala. 2011. CYANOS, a data management system for natural product drug discovery efforts. J. Chem. Inf. Model. 51: 171-180. (PMCID: PMC3026905).
- Vijayasarathi, U.V.R., S.V. Gupta, M. Chiu, Z. Liu, D.M. Lucas, D.J. Newman, J.M. Covey, A.D. Kinghorn, G. Marcucci, M.R. Grever, M.A. Phelps, and K.K. Chan. 2011. Characterization of silvestrol pharmacokinetics in mice using liquid chromatography-tandem mass spectrometry. AAPS J. 13:347-356. (PMCID: PMC3160157).
- Gupta, S.V., E.J. Stass, M.E. Davis, R.B. Edwards, G. Lozanski, N.A. Heerema, A. Lehman, X. Zhang, D. Jarjoura, J.C. Byrd, A.D. Kinghorn, M.A. Phelps, M.R. Grever, and D.M. Lucas. 2011. Resistance to silvestrol is mediated by MDR1/Pgp overexpression in a lymphoblastic leukemia cell line and is reversible by treatment with rapamycin. AAPS J. 13:357-364. (PMCID: PMC3160166).
- Deng, Y., Y.W. Chin, H.-B Chai, E.J. Carcache de Blanco, L.B.S. Kardono, S. Riswan, D.D. Soejarto, N.R. Farnsworth, and A.D. Kinghorn. 2011. Phytochemical and bioactivity studies on constituents of the leaves of Vitex quinata. Phytochem. Lett. 4: 213-217. (PMCID: PMC3182149).
- Kang, H.-S., A. Krunic, Q Shen, S.M. Swanson, and J. Orjala. 2011. Minutissamides A-D, antiproliferative cyclic decapeptides from the cultured cyanobacterium Anabaena minutissima. J. Nat. Prod. 74:1597-1603. (PMCID: PMC3142320).
- Ayers, S., T.N. Graf, A.F. Adcock, D.J. Kroll, Q. Shen, S.M. Swanson, M.C. Wani, C.J. Pearce, and N.H. Oberlies. 2011. Obionin B: An o-pyranonaphthoquinone decaketide from an unidentified fungus (MSX 63619) from the order Pleosporales. Tetrahedron Lett. 52: 5128-5130. (PMCID: PMC3183506).
- Sy-Cordero, A.A., T.N. Graf, A.D. Adcock, D.J. Kroll, Q. Shen, S.M. Swanson, M.C. Wani, C.J. Pearce, and N.H. Oberlies. 2011. Cyclodepsiptides, sesquiterpenoids and other cytotoxic metabolites from the filamentous fungus Trichothecium sp. (MSX 51320). J. Nat. Prod. 74:2137-2142 (PMCID: PMC3252997). (Erratum J. Nat. Prod. 75:307, 2012. (PMCID: PMC3339486).
- Ayers, S., B.M. Ehrmann, A.F. Adcock. D.J. Kroll, M.C. Wani, C.J. Pearce, and N.H. Oberlies. 2011. Thielavin B methyl ester: A cytotoxic benzoate trimer from an unidentified fungus (MSX 55526) from the order Sordariales. Tetrahedron Lett. 52:5733-5735. (PMCID: PMC3343773).
- Pan, L., S. Matthew, D.D. Lantvit, X. Zhang, T.N. Ninh, H. Chai, E.J. Carcache de Blanco, D.D. Soejarto, S.M. Swanson, and A.D. Kinghorn. 2011. Bioassay-guided isolation of constituents of Piper sarmentosum using a mitochondrial transmembrane potential assay. J. Nat. Prod. 74:2193-2199. (PMCID: PMC3206604).
- Zi, J., D.D. Lantvit, S.M. Swanson, J. Orjala. 2012. Lyngbyaurieidamines A and B, two anabaepeptins from the cultured freshwater cyanobacterium Lyngbya sp. (JAG 36.91). Phytochemistry 74:173-177. (PMCID: PMC3262893).
- Ayers, S., T.N. Graf, A.F. Adcock, D.J. Kroll, Q. Shen, S.M. Swanson, S. Matthew, E.J. Carcache de Blanco, M.C. Wani, B.A. Darveaux, C.J. Pearce, and N.H. Oberlies. 2012. Cytotoxic xanthone-anthraquinone heterodimers from an unidentified fungus of the order Hypocreales (MSX 17022). J. Antibiotics 65:3-8. (PMCID: 3267898).
- Pan, L., Y. Yong, U. Muñoz Acuña, Y. Deng, D.D. Lantvit, T.N. Ninh, H. Chai, E.J. Carcache de Blanco, D.D. Soejarto, S.M. Swanson, and A.D. Kinghorn. 2012. Isolation, structure elucidation, and biological evaluation of 16,23-epoxycucurbitacin constituents of Elaeocarpus chinensis. J. Nat. Prod. 75:444-452. (Included in a special issue in honor of Dr. Gordon M. Cragg). (PMCID: PMC3311738).
- Kang, H.-S., B.D. Santarsiero, H. Kim, A. Krunic, Q. Shen, S.M. Swanson, H. Chai, A.D. Kinghorn, and J. Orjala. 2012. Merocyclophanes A and B, antiproliferative cyclophanes from the cultured terrestrial cyanobacterium Nostoc sp. Phytochemistry 74:109-115. (PMCID: PMC3374012).
- Ren, Y., U. Muñoz Acuña, F. Jiménez, R. García, H.-B. Chai, J.C. Gallucci, N.R. Farnsworth, D.D. Soejarto, E.J. Carcache de Blanco, and A.D. Kinghorn. 2012. Cytotoxic and NF-kappaB inhibitory sesquiterpene lactones from Piptocoma rufescens. Tetrahedron 68:2671-2678. (PMCID: PMC3369275).
- Kim, H., A. Krunic, D. Lantvit, Q. Shen, D.J. Kroll, S.M. Swanson, and J. Orjala. 2012. Nitrile-containing fischerindoles from the cultured cyanobacterium Fischerella sp. Tetrahedron 68:3205-3209. (PMCID: PMC3315833).
- Kang, H.-S., A. Krunic, J. Orjala. 2012. Stigonemapeptin, an Ahp-containing depsipeptide with elastase inhibitory activity from the bloom-forming freshwater cyanobacterium Stigonema sp. J. Nat. Prod. 75:807-811. (PMCID: 3338906).
- Alinari, L., C.J. Prince, R.B. Edwards, W. Towns, R. Mani, A. Lehman, X. Zhang, D. Jarjoura, L. Pan, A.D. Kinghorn, M.R. Grever, R.A. Baiocchi, and D.M. Lucas. 2012. Dual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the novel translation inhibitor silvestrol. Clin. Cancer Res. 18:4600-4611. (PMCID: PMC3677230).
- Muñoz Acuña U., J. Wittwer, S. Ayers, C.J. Pearce, N.H. Oberlies, and E.J. Carcache de Blanco. 2012. Effects of (5Z)-7-oxozeaenol on MDA-MB-231 breast cancer cells. Anticancer Res. 32: 2415-2422. (PMCID: PMC3563245).
- Muñoz Acuña, U., J. Wittwer, S. Ayers, C.J. Pearce, N.H. Oberlies, and E.J. Carcache de Blanco. 2012. Effects of (5Z)-7-oxozeaenol on the oxidative pathway of cancer cells. Anticancer Res. 32: 2665-2671. (PMCID: PMC3563252).
- Ren, Y., M. Wei, P.C. Still, S. Yuan, Y. Deng, X. Chen, K. Himmeldirk, A.D. Kinghorn, and J. Yu. 2012. Synthesis and antitumor activity of ellagic acid peracetate. ACS Med. Chem. Lett. 3: 631-636. (PMCID: PMC3505040).
- El-Elimat, T., X. Zhang, D. Jarjoura, F.J. Moy, J. Orjala, A.D. Kinghorn, C.J. Pearce, and N.H. Oberlies. 2012. Chemical diversity of metabolites from filamentous fungi, cyanobacteria, and tropical plants relative to selected FDA-approved anticancer agents. ACS Med. Chem. Lett. 3:645-649. (PMCID: PMC3443637).
- Kang, H.S., A. Krunic, and J. Orjala. 2012. Sanctolide A, a 14-membered PK-NRP hybrid molecule from the cultured cynaobacterium Oscillaroria sancta (SAG 74.79). Tetrahedron Lett. 53:3563-3567. (PMCID: PMC3375721).
- Ayers, S., B. Ehrmann., A. Adcock, D.J. Kroll, E.J. Caracache de Blanco, Q. Shen, S. M. Swanson, J.O. Falkingham, M.C. Wani, S. Mitchell, C.J. Pearce, N.H. Oberlies. 2012. Peptaibols form two unidentified fungi of the order Hypocreales with cytotoxic, antibiotic, and anthelmintic activities. J. Peptide Sci. 18:500-510. (PMCID: PMC3494480).
- Kim, H., D. Lantvit, C.H. Hwang, D.J. Kroll, S.M. Swanson, S.G. Franzblau, and J. Orjala. 2012. Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola. Bioorg. Med. Chem. 20:5290-5295. (PMCID; PMC3429353).
- Kang, H.-S., S. Sturdy, A. Krunic, H.J Kim, Q. Shen, S.M. Swanson, and J. Orjala. 2012. Minutissamides A-H, antiproliferative cyclic lipodecapeptides from the cultured cyanbacterium cf. Ananbaena sp. Bioorg. Med. Chem. 20:6134-6143. (PMCID; PMC3471652).
- Figueroa, M., T.N. Graf, S. Ayers, A.F. Adcock, D.J. Kroll, J. Yang, S.M. Swanson, U. Muñoz Acuña, E.J. Carcache de Blanco, R. Agarwal, M.C. Wani, B.A. Darvceaux, C.J. Pearce, and N.H. Oberlies. 2012. Cytotoxic epipolythiodioxopiperazine alkaloids from filamentous fungi of the Bionectriaceae. J. Antibiot. 65:559-564. (PMCID: PMC3573876).
- Bueno Pérez, L., L. Pan, E.J. Sass, S.V. Gupta, A. Lehman, A.D. Kinghorn, and D.M. Lucas. 2013. Potentiating effect of the flavonolignan (-)-hydnocarpin in combination with vincristine in sensitive and P-gp-expressing acute lymphoblastic leukemic cell lines. Phytother. Res. 27:1735-1738. (PMCID: PMC3639301).
- Still, P.C., B. Yi, T. Gonzalez Muskus, L. Pan, R. Pavlovicz, H.-B. Chai, T. Ninh, C. Li, D.D. Soejarto, D. McKay, and A.D. Kinghorn. 2013. Alkaloids friom Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities. J. Nat. Prod. 76:243-249. (PMCID: PMC3580017).
- Alkachar H., R. Santhanam, J. Harb, D.M. Lucas, J. Oaks, C. Hickey, L. Pan, A.D. Kinghorn, M.A. Caligiuri, D. Perotti, J.C. Byrd, R. Garzon, M.R. Grever, and G. Marcucci. 2013. Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia. J. Hematol. Oncol. 6:21. (PMCID: PMC3623627).
- Pan, L., U. Muñoz Acuña, J. Li, N. Jena, T. Ninh, C.M. Pannell, H.-B. Chai, J.R. Fuchs, E.J. Carcache de Blanco, D.D. Soejarto, and A.D. Kinghorn. 2013. Bioactive flavaglines and other constituents isolated from Aglaia perviridis. J. Nat. Prod. 76:394-404. (Included in a special issue in honor of Dr. Lester A. Mitscher). (PMCID: PMC3606667).
- El-Elimat, T, M. Figueroa, H.A. Raja, T.N. Graf, A.F. Adcock, D.J. Kroll, C.S. Day, M.C. Wani, C.J. Pearce and N.H. Oberlies. 2013. Benzoquinones and terphenyl compounds as phosphodiesterase-4B inhibitors from a fungus of the order Chaetothyriales (MSX 47445). J. Nat. Prod. 76:382-387. (Included in a special issue in honor of Dr. Lester A. Mitscher). (PMCID: PMC3606633).
- Figueroa, M., H. Raja, J.O. Falkingham III, A.F. Adcock, D.J. Kroll, M.C. Wani, C.J. Pearce, and N.H. Oberlies. 2013. Peptaibols, tetrameric acid derivatives, isocoumarin and sesquiterpenes from a Bionectria species (MSZ 47401). J. Nat. Prod. 76:1007-1015. (PMCID: PMC3736820).
- El-Elimat, T., M. Figueroa, M., H.A. Raja, A.F. Adcock, D.J. Kroll, S.M. Swanson, M.C. Wani, C.J. Pearce, and N.H. Oberlies. 2013. Waol A, trans-dihydrowaol A, and cis-dihydrowaol A: polyketide-derived gamma-lactones from a Volutella species. Tetrahedron Lett. 54:4300-4302. (PMCID: PMC3743556).
- Bueno Pérez, L., J. Li, D.D. Lantvit, L. Pan, T.N. Ninh, H.-B. Chai, D.D. Soejarto, S.M. Swanson, D.M. Lucas, and A.D. Kinghorn. 2013. Bioactive compounds from Indigofera spicata. J. Nat. Prod. 76, 1498-1504 (PMCID: PMC3806331).
- Ren, Y., H. Chai, M. Goetz, and A.D. Kinghorn. 2013. A cytotoxic decanaphthanylpropenal derivative and tetrahydrofuran lignans from the stems of Cameraria latifolia. Tetrahedron Lett. 54:4854-4858. (Contribution from an Administrative Supplement to P01 CA125066 from NCCAM, NIH). (PMCID: PMC3755466).
- Ren, Y., F. Jiménez, R. García, M. Mejía, H. Chai, N.R. Farnsworth, D.D. Soejarto, and A.D. Kinghorn. 2013. A cytotoxic dimeric furanoheliangolide from Piptocoma rufescens. Tetrahedron Lett. 54:5457-5460. (PMCID: PMC3804354).
- El-Elimat, T., M. Figueroa, B.M. Ehrmann, N.B. Cech, C.J. Pearce, and N.H. Oberlies. 2013. High resolution MS, MS/MS and UV database of fungal secondary metabolites as a dereplication protocol for bioactive natural products. J. Nat. Prod. 76:1709-1716. (PMCID: PMC3856222).
- Spear, S.A., S.S. Burns, J.L. Oblinger, Y. Ren, L. Pan, A.D. Kinghorn, D.B. Welling, and L.-S. Chang. 2013. Natural compounds as potential treatments of NF2-deficient schwannoma and meningioma: cucurbitacin D and goyazensolide. Otol. Neurotol. 34:1519-1527. (PMCID: PMC4334125).
- Kogure, T., A.D. Kinghorn, I. Yan, B. Bolon, D.M. Lucas, M.R. Grever, and T. Patel. 2013. Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer. PLoS One 8: e76136. (PMCID: PMC3784426).
- Li, J., L. Pan, Y. Deng, U. Muñoz-Acuña, C. Yuan, H. Lai, H.-B. Chai, T.E. Chagwedera, N.R. Farnsworth, E.J. Carcache de Blanco, C. Li, D.D. Soejarto, and A.D. Kinghorn. 2013. Sphenostylins A-K, bioactive modified isoflavonoid constituents of the root bark of Sphenostylis marginata ssp. erecta. J. Org. Chem 78:10166-10177. (PMCID: PMC3827909).
- Muñoz Acuña, U., Q. Shen, Y. Ren, D.D. Lantvit, J.A. Wittwer, A.D. Kinghorn, S.M. Swanson, and E.J. Carcache de Blanco. 2013. Goyazensolide induces apoptosis in cancer cells in vitro and in vivo. Int. J. Cancer Res., 9:36-53. (Contribution from a Minority Supplement to P01 CA125066, to promote the research work of Dr. Esperanza Carcache de Blanco). (PMCID: PMC4303185).
- Yong, Y., S. Matthew, J. Wittwer, L. Pan, Q. Shen, A.D. Kinghorn, S.M. Swanson, and E.J. Carcache de Blanco. 2013. Dichamanetin inhibits cancer cell growth by affecting ROS-related signaling components through mitochondrial-related apoptosis. Anticancer Res. 33:5349-5355. (PMICID: PMC4281931).
- Muñoz Acuña U, N. Fatima, S. Ahmed, L.C. Chang, and E.J. Carcache de Blanco. 2013. Apoptotic effect of wortmannolone on cancer cells through potent ROS induction. Int. J. Cancer Res. 47:1185-1195. (Contribution from a Minority Supplement to P01 CA125066, to promote the research work of Dr. Esperanza Carcache de Blanco). (PMCID:PMC4318515).
- Bueno Pérez, L., L. Pan, U. Muñoz Acuña, J. Li, H.-B. Chai, J.C. Galucci, T.N. Ninh, E.J. Carcache de Blanco, D.D. Soejarto, and A.D. Kinghorn. 2014. Caeruleanone A, a rotenoid with a new arrangement of the D-ring from the fruits of Milletia caerulea. Org. Lett., 16:1462-1465. (PMCID:PMC3954433).
- Ren, Y., C. Yuan, Y. Qian, H. Chai, X. Chen, M. Goetz, and A.D. Kinghorn. 2014. Constituents of an extract of Cryptocarya rubra housed in a repository with cytotoxic and glucose transport inhibitory effects. J. Nat. Prod. 77:550-556. (Included in a special issue in honor of Prof. Otto Sticher). (Contribution from an Administrative Supplement to P01 CA125066 from NCCAM, NIH). (PMCID:PMC4047178).
- Muñoz Acuña, U., S. Matthew, L. Pan, A.D. Kinghorn, S.M. Swanson, and E.J. Carcache de Blanco. 2014. Apoptosis induction by 13-acetoxyrolandrolide through the mitochondrial intrinsic pathway. Phytotherapy Res. 28:1045-1053. (Contribution from a Minority Supplement to P01 CA125066, to promote the research work of Dr. Esperanza Carcache de Blanco). (PMCID: PMC4055509).
- Ren, Y., D.D. Lantvit, Y. Deng, R. Kanagasabai, J.C. Gallucci, T.N. Ninh, H.-B. Chai, D.D. Soejarto, J.R. Fuchs, J.C. Yalowich, J. Yu, S.M. Swanson, and A.D. Kinghorn. 2014. Potent cytotoxic arylnaphthalene lignan lactones from Phyllanthus poilanei. J. Nat. Prod. 77:1494-1504. (PMCID:PMC4073661).
- Luo, S., A., H.-S. Kang, A. Krunic, G.E. Chlapala, G. Cai, W.-L. Chen, S.G. Franzblau, S.M. Swanson, and J. Orjala. 2014. Carbamidocyclophanes F and G with anti-Mycobacterium tuberculosis activity from the freshwater cyanobacterium Nostoc sp.. Tetrahedron Lett. 55:686-689. (PMCID:PMC4161986).
- Luo, S., A. Krunic, H.-S. Kang, W.-L. Chen, J.L. Woodard, J.R. Fuchs, S.M. Swanson, and J. Orjala. 2014. Trichormamides A and B with antiproliferative activity from the cultured freshwater cyanobacterium Trichormus sp. UIC 10339. J. Nat. Prod. 77:1871-1880. (PMCID:PMC4143178).
- Deng, Y., J. Chu, Y. Ren, Z. Fan, X. Ji, B. Mundy, S. Yuan, T. Hughes, S. He, J. Zhang, B. Cheema, A. Camardo, Y. Xia, L-C. Wu, L.-S. Wang, X. He, A. D. Kinghorn, X. Li, M.A. Caligiuri, and J. Wu. 2014. The natural product phyllanthusmin C selectively enhances IFN-gamma production by human natural killer cells through upregulation of TLC-mediated NF-kappa B signaling. J. Immunol. 193:2994-3002. (PMCID: PMC4162489).
- Yong, Y., L. Pan, Y. Ren, N. Fatima, S. Ahmed, L.C. Chang, X. Zhang, A.D. Kinghorn,. S.M. Swanson, and E.J. Carcache de Blanco. 2014. Assay development for the discovery of semaphorin 3B inducing agents from natural product sources. Fitoterapia 98C, 184-191. (Contribution from a Minority Supplement to P01 CA125066, to promote the research work of Dr. Esperanza Carcache de Blanco). (PMCID: PMC4196688).
- VanderMolen, K.M., B.A. Darveaux, W.L. Chen, S.M. Swanson, C.J. Pearce, and N.H. Oberlies. 2014. Epigenetic manipulation of a filamentous fungus by the proteasome-inhibitor bortezomib induces the production of an additional secondary metabolite. RSC Adv. 4:18329-18335. (PMCID: PMC4061710).
- El-Elimat, T., H.A. Raja, C.S. Day, W.-L. Chen, S.M. Swanson, and N.H. Oberlies. 2014. Greensporones: Resorcylic acid lactones from an aquatic Halenospora sp. J. Nat. Prod. 77: 2088-2098. (PMCID: PMC4176394).
- Callahan, K.P., M. Minhajuddin, C. Corbett, E. Lagadinou, R.M. Rossi, V. Grose, M.M. Balys, L. Pan, S. Jacob, A. Frontier, M.R. Grever, D.M. Lucas, A.D. Kinghorn, J. Liesveld, M.W. Becker, and C.T. Jordan. 2014. Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity. Leukemia 28:1960-1968. (PMCID:PMC4148474).
- Pan, L., C. Terrazas, U. Muñoz Acuña, T.N. Ninh, H. Chai, E.J. Carcache de Blanco, D.D. Soejarto, A.R. Satoskar, and A.D. Kinghorn. 2014. Bioactive indole alkaloids isolated from Alstonia angustifolia. Phytochem. Lett. 10:liv-lix (Special section of issue 4 in honor of the late Prof. Andrew Marston). (PMCID: PMC4287998).
- Patton, J.T., M.E. Lustburg, G. Lozanski, S.L. Garman, W.H. Towns, C.M. Drohan, A. Lehman, X. Zhang, B. N. Bolon, L. Pan, A.D. Kinghorn, M.R. Grever, D.M. Lucas, and R.A. Baiocchi. 2015. The translation inhibitor silvestrol exhibits direct anti-tumor activity while preserving innate and adaptive immunity against EBV-driven lymphoproliferative disease. Oncotarget 6:2693-2708. (PMCID: PMC4413611).
- El-Elimat, T., H.A. Raja, M. Figueroa, S.M. Swanson, J.O. Falkinham III, D.M. Lucas, M.R. Grever, M.C. Wani, C.J. Pearce, and N.H. Oberlies. 2015. Sorbicillinoid analogues with cytotoxic and selective anti-Aspergillus activities from Scytalidium album. J. Antibiot. 68:191-196. (PMCID: PMC4372511).
- El-Elimat, T., M. Figueroa, H.A. Raja,T.N. Graf, S.M. Swanson, J.O. Falkinham III, M.C. Wani, C.J. Pearce, and N.H. Oberlies. 2015. Biosynthetically distinct cytotoxic polyketides from Setophoma terrestris. Eur. J. Org. Chem., 109-121. (PMCID: PMC4283843).
- Ren, Y., C. Yuan, Y. Deng, R. Kanagasabai, T.N. Ninh, V.T. Tu, H.-B.Chai, D.D. Soejarto, J.R. Fuchs, J.C. Yalowich, J. Yu, and A.D. Kinghorn. 2015. Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis. Phytochemistry 111:132-140. (PMCID:PMC4333069).
- Zhao, M., M.M. Onakpa, W.-L. Chen, B.D. Santarsiero, S.M. Swanson, J.E. Burdette, I.U. Asumzu, and C.-T. Che. 2015. 17-Norpimaranes and (9betaH)-17-norpimaranes from the tuber of Icacina tricantha. J. Nat. Prod. 78:789-796. (PMCID: PMC4703125).
- Muñoz Acuña, U., J. Zi, J. Orjala, and E.J. Carcache de Blanco. 2015. Ambiguine I isonitrile from Fischerella ambigua induces caspase-Independent cell death in MCF-7 hormone dependent breast cancer cells. Int. J. Cancer Res. 49:1655-1662. (PMCID:PMC4703120).
- Luo, S., H.-S. Kang, A. Krunic, W.-L. Chen, J. Yang, J.L. Woodard, J.R. Fuchs, S.H. Cho, S.G. Franzblau, S.M. Swanson, and J. Orjala. 2015. Trichomamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater bacterium cf. Oscillatoria sp. UIC 10045. Bioorg. Med. Chem. 23:3153-3162. (PMCID:PMC4469202).
- Luo, S., A. Krunic, G.E. Chlapala, and J. Orjala. 2015. Microseriamide from the freshwater cyanobacterium Microseira sp. UIC 10445. Phytochem. Lett. 13:47-52. (PMCID:PMC4467913).
- Pan, L., U. Muñoz Acuña, H. Chai, H.-Y. Park, T.N. Ninh, B.V. Thanh, E.F. Merino, M.B. Cassera, L.H. Rakotondraibe, E.J. Carcache de Blanco, D.D. Soejarto, and A.D. Kinghorn. 2015. New bioactive lupane triterpene coumaroyl esters isolated from Buxus cochinchinensis. Planta Med. 81:1133-1140. (Special issue in honor of the 75th birthday of Prof. Dr. Adolf Nahrstedt). (PMCID:PMC:4545412).
- Alali, F., T. El-Elimat, H. Albataineh, Q. Al-Balas, M. Al-Gharaibeh, J.O. Falkingham, III, W.-L. Chen, S.M. Swanson, and N.H. Oberlies. 2015. Cytotoxic homoisoflavones from the bulbs of Bellevalia eigii. J. Nat. Prod. 78:1708-1715. (PMCID: PMC4615712).
- Sica, V.P., H.A. Raja, T. El-Elimat, V. Kertesz, G. J. Van Berkel, C. J. Pearce, and N.H. Oberlies. 2015. Dereplicating and spatial mapping of secondary metabolites from fungal cultures in situ. J. Nat. Prod. 78:1926-1936. (PMCID: PMC4570219).
- Kaur, A., H.A. Raja, B.A. Darveaux, W.L. Chen, S.M. Swanson, C.J. Pearce, and N.H. Oberlies. 2015. New diketopiperazine dimer from a filamentous fungal isolate of Aspergillus sydowii. Magn. Reson. Chem. 53:616-619. (PMCID:PMC4692248).
- Paschall, A.V., D. Yang, C. Lu, J.H. Choi, X. Li, F. Liu, M. Figueroa, N.H. Oberlies, C. Pearce, W.B. Bollag, A. Nayak-Kapoor, and K. Liu. 2015. H3K9 trimethylation silences Fas expression to confer colon carcinoma immune escape and 5-fluorouracil chemoresistance. J. Immunol. 195:1868-1882. (PMCID: PMC4530033).
- Ren, Y., A. VanSchoiack, H.-B. Chai, M. Goetz, and A.D. Kinghorn. 2015. Cytotoxic barringenol-like triterpenoids from an extract of Cyrilla racemiflora housed in a repository. J. Nat. Prod. 78:2440-2446. (Contribution from an Administrative Supplement to P01 CA125066 from NCCAM, NIH). (PMCID:PMC4619146).
- Sy-Cordero, A.A., Figueroa, M., Raja, H.A., Meza Aviña, M.E., Croatt, M.P., Adcock, A.F., Kroll, D.J., Wani, M.C., Pearce, C.J., and Oberlies, N.H. 2015. Spiroscyatalin, a new tetramic acid and other metabolites of mixed biogenesis from Scytalidium cuboideum. Tetrahedron 71:8899-8904. (PMCID:PMC4624200).
- Fakhouri, L., T. El-Elimat, D.P. Hurst, P.H. Reggio, C.J. Pearce, N.H. Oberlies, and M.P. Croatt. 2015. Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analogues. Bioorg. Med. Chem. 23, 6993-6999. (PMCID:PMC4661079).
- Zhao, M., M.M. Onakpa, B.D. Santarsiero, W.-L. Chen, K.M. Szymulanska-Ramamurthy, S.M. Swanson, J.E. Burdette, I.U. Asuma, and C.-T. Che. 2015. (9betaH)-pimaranes and derivatives from the tuber of Icacina tricantha. J. Nat. Prod. 78:2731-2737. (PMCID:PMC4703074).
- Krunic, A., J. Orjala. 2015. Application of high field NMR spectroscopy for characterization and quantitation of submilligram quantities of isolated natural products. Magn. Reson. Chem. 53:1043-1050. (PMCID:PMCID:4752180).
- Chen, W.-L., L. Pan, A.D. Kinghorn, S.M. Swanson, and J.E. Burdette. 2016. Silvestrol induces autophagy and apoptosis in human melanoma cells. BMC Cancer 16:17. (PMCID:PMC4712514).
- Oblinger, J.L., S.S. Burns, J. Huang, L. Pan, Y. Ren, R. Shen, B. Miles-Markley, A.C. Moberly, A.D. Kinghorn, D.B. Welling, and L.-S. Chang. 2016. Components of the eIF4F complex are potential therapeutic targets for malignant peripheral nerve sheath tumors and vestibular schwannoma. Neuro-Oncol. 18:1265-1277. (PMCID:PMC4998994).
- Muñoz Acuña, U., P.J. Blanco Carcache, S. Matthew, and E.J. Carcache de Blanco. 2016. New acyclic bis phenylpropanoid and neolignans, from Myristica fragrans Houtt., exhibiting PARP1 and NF-kappaB inhibitory effects. Food Chem. 202:269-275. (Contribution from a Minority Supplement to P01 CA125066, to promote the research work of Dr. Esperanza Carcache de Blanco). (PMCID: PMC4770456).
- Othman, N, L. Pan, M. Mejin, J. Voong, H. Chai, C.M. Pannell, A.D. Kinghorn, and T.C. Yeo. 2016. Cyclopenta[b]benzofuran and secodammarane derivatives from the stems of Aglaia stellatopilosa. J. Nat. Prod. 79:784-791. (PMCID: PMC4841703).
- Ren, Y., P.A. Benatrehina, U. Muñoz Acuña, C. Yuan, H.-B. Chai, T.N. Ninh, E.J. Carcache de Blanco, D.D. Soejarto, and A.D. Kinghorn. 2016. Isolation of bioactive rotenoids and isoflavonoids from the fruits of Millettia caerulea. Planta Med. 82:1096-1104. (Special issue in honor of Emeritus Prof. Dr. Kurt Hostettmann). (PMCID: PMC4956498).
- Guo, B., M.M. Onakpa, X.-J. Huang, B.D. Santarsiero, W.-L. Chen, M. Zhao, X.-Q. Zhang, S. M. Swanson, J.E. Burdette, and C.-T. Che. 2016. Di-nor- and 17-nor-pimaranes from Icacina trichantha. J. Nat. Prod. 79:1815-1821. (PMCID: PMC5096845).
- Zewdu, A., G. Lopez, D. Braggio, C. Kenny, D. Constantino, H.K. Bid, K. Batte, O.H. Iwenofu, N.H. Oberlies, C.J. Pearce, A.M. Strohecker, D. Lev, and R.E. Pollock. 2016. Verticillin A inhibits leiomyosarcoma and malignant peripheral nerve sheath tumor growth via induction of apoptosis. Clin. Exp. Pharmacol. 6(6):1000221. (PMCID: PMC5295762).
- Gonzalez-Medina, M., F.D. Prieto-Martinez, J.J. Naveja, O. Mendez-Lucio, T. El-Elimat, C.J. Pearce, N.H. Oberlies, M. Figueroa, and J.L. Medina-Franco. 2016. Chemoinformatic expedition of the chemical space of fungal products. Future Med. Chem. 8:1399-1412. (PMCID:PMC5558535).
- Brooks, W.C., N.D. Paguigan, H.A. Raja, F.J. Moy, N.B. Cech, C.J. Pearce, and N.H. Oberlies. 2017. qNMR for profiling the production of fungal secondary metabolites. Magn. Reson. Chem. 55:670-676. (PMCID: PMC5459663).
- Paguigan, N.D., T. El-Elimat, D. Kao, H.A. Raja, C.J. Pearce, and N.H. Oberlies. 2017. Enhanced dereplication of fungal cultures via use of mass defect filtering. J. Antibiotics 70:553-561. (PMCID: PMC5407915).
- Ren, Y., W.-L. Chen, D.D. Lantvit, E.J. Sass, P. Shriwas, T.N. Ninh, H.-B. Chai, X. Zhang, D.D. Soejarto, X. Chen, D.M. Lucas, S.M. Swanson, J.E. Burdette, and A.D. Kinghorn. 2017. Cardiac glycoside constituents of Streblus asper with potential antineoplastic activity. J. Nat. Prod. 80:648-658. (Special issue in honor of Professor Philip Crews). (PMCID: PMC5365359).
- Chen, W.-L., Y. Ren, J. Ren, C. Erxleben, M.E. Johnson, S. Gentile, A.D. Kinghorn, S.M. Swanson, and J.E. Burdette. 2017. (+)-Strebloside-induced cytotoxicity in ovarian cells is mediated through cardiac glycoside signaling networks. J. Nat. Prod. 80:659-669. (Special issue in honor of Professor Philip Crews). (PMCID: PMC5768141).
- Muñoz Acuña, U., R.W. Curley, Jr., N. Fatima, S. Ahmed, L.C. Chang, and E.J. Carcache de Blanco. 2017. Differential effect of wortmannolone derivatives on MDA-MD-231 breast cancer cells. Anticancer Res. 37:1617-1623. (Contribution from a Minority Supplement to P01 CA125066, to promote the research work of Dr. Esperanza Carcache de Blanco). (PMCID: PMC5488875).
- May, D., W.-L. Chen, D.D. Lantvit, X. Zhang, J.E. Burdette, A. Eustaquio, and J. Orjala. 2017. Merocyclophanes C and D from the cultivated freshwater cyanobacterium Nostoc sp. (UIC 10110). J. Nat. Prod. 80:1073-1080. (PMCID:PMC5898374).
- Ren, Y., J.C. Gallucci, and A.D. Kinghorn. 2017. An intramolecular CAr‒H···O=C hydrogen bond and the configuration of rotenoids. Planta Med. 83:1194-1199. (Special issue in honor of Professor Dr. M. Wichtl). (PMCID: PMC5617795).
- Wang, J., X. Zhu, S. Kolli, H. Wang, C.J. Pearce, N.H. Oberlies, and M.A. Phelps. 2017. Plasma pharmacokinetics and bioavailability of verticillin A following different routes of administration in mice using liquid chromatography tandem mass spectrometry. J. Pharm. Biomed. Anal. 139:187-192. (PMCID: PMC5399420).
- Sica V.P., E.R. Rees, H.A. Rafa, J. Rivera-Chávez, J.E. Burdette, C.J. Pearce, and N.H. Oberlies. 2017. In situ mass spectrometry monitoring of fungal cultures led to the identification of four peptaibols with a rare threonine residue. Phytochemistry 143:45-53. (PMCID: PMC5603414).
- Rivera-Chávez, H.A. Rafa, T.N. Graf, J.E. Burdette, C.J. Pearce, and N.H. Oberlies. 2017. Biosynthesis of fluorinated peptaibols using a site-directed building block incorporation approach. J. Nat. Prod. 80:1883-1892. (PMCID: PMC5485375).
- Henkin, J.M., K. Sydara, M. Xayvue, O. Souliya, A.D. Kinghorn, J.E. Burdette, W.-L. Chen, B. Elkington, and D.D. Soejarto. 2017. Revisiting the linkage between ethnomedical use and development of new medicines: A novel plant collection strategy towards the discovery of anticancer agents. J. Med. Plants Res. 11:621-634. (PMCID: PMC5686776).
- Gonzalez-Medina, M., J.R. Owen, T. El-Elimat, C.J. Pearce, N.H. Oberlies, M. Figueroa, and J.L. Medina-Franco. 2017. Scaffold diversity of fungal metabolites. Front. Pharmacol. 8:180 (PMCID: PMC5376591).
- Paguigan, N.D., M.H. Al-Huniti, H.A. Raja, H.A., A. Czarnecki, J.E. Burdette, M. Gonzalez-Medina, J.L. Medina-Franco, S.J. Polyak, C.J. Pearce, M.P. Croatt, M.P. and N.H. Oberlies. 2017. Chemoselective fluorination and chemoinformatic analysis of griseofulvin: Natural vs. fluorinated fungal metabolites. Bioorg. Med. Chem. 25:5238-5246 (PMCID: PMC5632135).
- Rivera-Chávez, J., H.A. Raja, T.N. Graf, J.M. Gallagher, P. Metri, D. Xue, C.J. Pearce, and N.H. Oberlies. 2017. Prealamethicin F50 and related peptaibols from Trichoderma arundinaceum: Validation of their authenticity via in situ chemical analysis. RSC Adv. 7:45733-45741. (PMCID:PMC5786278).
- Oblinger J.L., S.S. Burns, J. Huang, L. Pan, Y. Ren, R. Shen, A.D. Kinghorn, D.B. Welling, and L.S. Chang. 2018. Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation. Exp Neurol. 299: 299-307. (PMCID: PMC5723558).
- Wilson T.A., R.J. Tokarski II, P. Sullivan, R.M. Demoret, J. Orjala, L. Rakotondraibe, and J.R. Fuchs. 2018. Scalable solid-phase total synthesis of scytonemide A employing Weinreb AM resin. J Nat Prod. 81:534-42. (Special issue in honor of Dr. Susan Band Horwitz). (PMCID: PMC5866229).
- Ren, Y, J.C. Gallucci, X. Li, L. Chen, J. Yu, and A.D. Kinghorn. 2018. Crystal structures and human leukemic cell inducible activities of parthenolide analogues isolated from Piptocoma rufescens. J Nat Prod. 81:554-61. (Special issue in honor of Dr. Susan Band Horwitz). (PMCID: PMC5866214).
- Kang H-S, D.S. May, B.D. Santarsiero, A. Krunic, Q. Shen, J.E. Burdette, S.M. Swanson, and J. Orjala. 2018. Ribocyclophanes A-E, glycosylated cylindrocyclophanes with antiproliferative activity from two cultured terrestrial cyanobacteria. J Nat Prod. 81:572-8. (Special issue in honor of Dr. Susan Band Horwitz). (PMCID: PMC5898370).
- Lu C, D. Yang, M.E. Sabbatini, A.H. Colby, M.W. Grinstaff, N.H. Oberlies, C.J. Pearce, and K. Liu. 2018. Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells. BMC Cancer 18:149. (PMCID: PMC5801751).
- El-Elimat T, J. Rivera-Chávez, J.E. Burdette, A. Czarnecki, M.B. Alhawarri, M. Al-Charaibeh, F. Alali, and N.H. Oberlies. 2018. Cytotoxic homoisoflavonoids from the bulbs of Bellevalia flexuosa. Fitoterapia 127:201-6. (PMCID: PMC5984119).
- Crnkovic C.M., D.S. May, and J. Orjala. The impact of culture conditions on growth and metabolic profiles of freshwater cyanobacteria. J Appl Phycol. 30:375-84. (PMCID: PMC6171529).
- Woodard J.L., A.C. Huntsman, P.A. Patel, H-B Chai, R. Kanagasabai, S. Karmahapatra, A.N. Young, Y. Ren, J.C. Yalowich, A.D. Kinghorn, J.E. Burdette, and J.R. Fuchs. 2018. Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones. Bioorg Med Chem. 26:2354-64. (PMCID: PMC5962029).
- Muñoz Acuña U., S. Mo, Zi, J. Orjala, E.J. and Carcache de Blanco. 2018. Hapalindole H. induces apoptosis as an inhibitor of NF-kappaB and affects the intrinsic mitochondrial pathway in PC-3 androgen-insensitive prostate cancer cells. Anticancer Res. 38:3299-307. (PMCID: PMC5986100).
- Young A.N., D. Herrera, A.C. Huntsman, M.A. Korkmaz, D.D. Lantvit, S. Mazumdar, A.S. Kolli, C. Coss, S. King, H. Wang, S.M. Swanson, A.D. Kinghorn , X. Zhang, M.A. Phelps, L.N. Aldrich, J.R. Fuchs, and J.E. Burdette. 2018. Phyllanthusmin derivatives induce apoptosis and reduce tumor burden in high grade serous ovarian cancer by late-stage autophagy inhibition. Mol Cancer Ther. 17:2123-35. (PMCID: PMC6168422).
- Ren Y, G.D. Anaya-Eugenio, A.A. Czarnecki, T.N. Ninh, C. Yuan, H-B Chai, D.D. Soejarto, J.E. Burdette, E.J. Carcache de Blanco, and A.D. Kinghorn. 2018. Cytotoxic and NF-kappaB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives. Bioorg Med Chem. 26:4452-60. (PMCID: PMC6177235).
- Crnkovic C.M., A. Krunic, D.A. May, T.A. Wilson, D. Kao, J.E. Burdette, J.R. Fuchs, N.H. Oberlies, and J. Orjala. 2018. J. Calothrixamides A and B, two acyl amides from the cultured cyanobacterium Calothrix sp. UIC 10520. J Nat Prod. 81:2083-90. (PMCID: PMC6359934).
- Amrine C.S.M., H.A. Raja, B.A. Darveaux, C.J. Pearce, and N.H. Oberlies. 2018. Media studies to enhance the production of verticillins facilitated by in situ chemical analysis. J Ind Microbiol Biotechnol. 45:1053-65. (PMCID: PMC6251749).
- Kao, D., J.M. Henkin, D.D. Soejarto, A.D. Kinghorn, N.H. Oberlies. Non-destructive chemical analysis of a Garcinia mangostana L. (Mangosteen) herbarium specimen. Phytochem. Lett. 28:124-9. (PMCID: PMC6317376).
- Al-Huniti M.H., J. Rivera-Chávez, K.L. Colón, J.L. Stanley, J.E. Burdette, C.J. Pearce, N.H. Oberlies, and M.P. Croatt. 2018. Development and utilization of a palladium-catalyzed dehydration of primary amides to form nitriles. Org Lett. 20:6046-50. (PMCID:PMC6179452).
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- Amrine, C.S.M., J.L. Long, H.A. Rafa, S.J. Kurina, J.E. Burdette, C.J. Pearce, and N.H. Oberlies. 2019. Engineering fluorine into verticillins (epipolythiodioxopiperazine alkaloids) via precursor-directed biosynthesis. J Nat Prod. 82:3104-3110. (PMCID:PMC6996222).
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- Kao, D., L. Flores-Bocanegra, H.A. Raja, B.A. Darveaux, C.J. Pearce, and N.H. Oberlies. 2020. New dogs for old tricks: Two new macrocyclic trichothecene epimers and absolute configuration of 16-hydroxyverrucarin B. Phytochemistry 172: art. no. 112238. (PMCID: PMC7050405).
- Ren, Y., Q. Tan, K. Heath, S. Wu, J.R. Wilson, J. Ren, P. Shriwas, C. Yuan, T.N. Ninh, H.-B. Chai, X. Chen, D.D. Soejarto, M.E. Johnson, J.B. Burdette, and A.D. Kinghorn. 2020. Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper. Bioorg. Med. Chem. 28: art. no. 115301. (PMCID: PMC7029422).
- Chang, L.-S., J.L. Oblinger, S.S. Burns, J. Huang, L.W. Anderson, M.G. Hollingshead, R. Shen, L. Pan, G. Agarwal, Y. Ren, R. Roberts, B.R. O’Keefe, A.D. Kinghorn, and J.M. Collins. 2020. Targeting protein translation by rocaglamide and didesmethylrocaglamide to treat MPNST and other sarcomas. Mol. Cancer Ther. 19:731-741. (PMCID: PMC7056570).
- Ren, Y., H.T. Ribas, K. Heath, S. Wu., J. Ren, P. Shriwas, X. Chen, M.E. Johnson, X. Cheng, J.E. Burdette, and A.D. Kinghorn. 2020. Na+/K+-ATPase-targeted cytotoxicity of (+)-digoxin and several semi-synthetic derivatives. J. Nat. Prod. 83:638-648. (PMCID: PMC7243443). (Special issue in honor of Dr. J. Clardy).
- Knowles, S.L., H.A. Raja, I.H. Isawi, L. Flores-Bocanegra, P.H. Reggio, C.J. Pearce, J.E. Burdette, A. Rokas, and N.H. Oberlies. 2020. Wheldone: Characterization of a unique scaffold from the coculture of Aspergillus fischeri and Xylaria flabelliformis. Org. Lett. 22:1878-1882. (PMCID: PMC7153779).
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- Sullivan, P, A. Krunic, J.E. Burdette, and J. Orjala. 2020. Laxaphycin B5 and B6 from the cultured cyanobacterium cf. Phormidium sp. UIC 10484. J Antibiot. 73:526-533. (PMCID: PMC7338234). (Special issue in honor of Dr. W. Fenical).
- Anaya-Eugenio, G.D., C.Y. Tan, H.L. Rakotondraibe, and E. J. Carcache de Blanco. 2020. Tumor suppressor p53 independent apoptosis in HT-29 cells by auransterol from Penicillium aurantiacobrunneum. Biomed. Pharmacother. 127: art. no. 110124. (PMCID: PMC7584345).
- Al Subeh, Z.Y., H.A. Raja, S. Monro, L. Flores-Bocanegra, T. El-Elimat, C.J. Pearce, S.A. McFarland, and N.H. Oberlies. 2020. Enhanced production and anticancer properties of photoactivated perylenequinones. J. Nat. Prod. 83:2490-2500. (Erratum 2020 J. Nat. Prod. 83: 3765-3766). (PMCID: PMC7493285).
- Li, S., S.A. Newmister, A.N. Lowell, J. Zi, C.R. Chappell, F. Yu, J. Orjala, R.M. Williams, and D.H. Sherman. 2020. Control of stereoselectivity in diverse hapalindole metabolites is mediated by cofactor induced combinatorial pairing of Stig cyclases. Angew. Chem. Int. Ed. Engl. 59:8166-8172. (PMCID: PMC7274885).
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- El-Alimat T, M.B. Alhawarri, J. Rivera-Chávez, J.E. Burdette, A. Czarnecki, M. Al-Gharaibeh, A.H. Al Sharie, A. Alhusban, F.Q. Alali, and N.H. Oberlies. 2020. Phenethylisoquinoline alkaloids from the leaves of Androcymbium palaestinum. Fitoterapia 146: art. no. 104706. (PMCID: PMC7871506).
- Anaya-Eugenio, G.D., N.A. Eggers, Y. Ren, J.A. Rivera-Chávez, A.D. Kinghorn, and E.J. Carcache de Blanco. 2020. Apoptosis induced by (+)-betulin through NF-kappaB inhibition in MDA-MB-321 breast cancer cells. Anticancer Res. 40:6637-6647. (PMCID: PMC7849021).
- Guo, B., M. Zhao, Z. Wu, M.M. Onakpa, J.E. Burdette, and C.-t. Che. 2020. 19-Nor-pimaranes from Icania trichantha. Fitoterapia 146: art. no. 104612. (Erratum 2020 Fitoterapia 146: art. no. 104656). (PMCID: PMC7374768).
- Flores-Bocanegra L., H.A. Raja, J.W. Bacon, A.C. Maldonado, J.E. Burdette, J.O. Falkinham III, C.J. Pearce, and N.H. Oberlies. 2021. Cytotoxic naphthoquinone analogues, including heterodimers, and their structure elucidation using LR-HSQMBC NMR experiments. J. Nat. Prod. 84: 771-778). (PMCID: PMC8005429). (Special issue in honor of Dr. A.D. Kinghorn).
- Anaya-Eugenio, G.D., P.J. Blanco Carcache, T.N. Ninh, Y. Ren, D.D. Soejarto, and A.D. Kinghorn. 2021. A pentamethoxylated flavone from Glycosmis ovoidea promotes apoptosis through the intrinsic pathway and inhibits migration of MCF-7 breast cancer cells. Phytother. Res. 35: 1634-1645. (PMCID: PMC8005457).
- Al Subeh, Z.Y., N.-Q., Chu, J.T. Korunes-Miller, L.L. Tsai, T.N. Graf, Y.P. Hung, C.J. Pearce, M.W. Grinstaff, A.H. Colby, Y.L. Colson, and N.H. Oberlies. 2021. Delivery of eupenifeldin via polymer-coated surgical buttresses prevents local lung cancer recurrence. J. Controlled Rel. 331:260-269. (PMCID: PMC7946725).
- Al Subeh, Z.Y., H.A. Raja, A. Maladonado, J.E. Burdette, C.J. Pearce, and N.H. Oberlies. 2021. Thielavins: tuned biosynthesis and LR-HSQMBC for structure elucidation. J. Antibiot. 74:300-306. (PMCID: PMC8084880).
- Flores-Bocanegra L., M. Augustinović, H.A. Raja, S.J. Kurina, A.C. Maldonado, J.E. Burdette, J.O. Falkingham III, C.J. Pearce, and N.H. Oberlies. 2021. Cytotoxic and antimicrobial drimane meroterpenoids from a fungus of the Stictidaceae (Ostropales, Ascomycota). Tetrahedron Lett. 68: 152896. (PMCID: PMC9012486).
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- Knowles SL, C.D. Roberts, M. Augustinović, L. Flores-Bocanegra, H.A. Raja, K.N. Heath-Borrero, J.E. Burdette, J.O. Falkinham III, C.J. Pearce, and N.H. Oberlies. 2021. Opportunities and limitations for assigning relative configurations of antibacterial bislactones using GIAO NMR shift calculations. J. Nat. Prod. 84:1254-1260. (PMCID: PMC8108483).
- Sun, M., B. Guo, M. Xu, M. Zhao, M.M. Onakpa, Z. Wu, J.E. Burdette, and C.T. Che. 2021. (9βH)- and 17-Nor-pimaranes from Icacina oliviformis. J. Nat. Prod. 84:949-955. (PMCID: PMC8344086).
- Amrine, C.S.M., A.C. Huntsman, M.G. Doyle, J.E. Burdette, C.J. Pearce, J.R. Fuchs, and N.H. Oberlies. 2021. Semisynthetic derivatives of the verticillin class of natural products through acylation of the C11 hydroxy group. ACS Med. Chem. Lett. 12:625-630. (PMCID: PMC8040035).
- El-Elimat, T., M. Figueroa, H.A. Rafa, S. Alnabulsi, and N.H. Oberlies. 2021. Coumarins, dihydroisocoumarins, a dibenzo-alpha-pyrone, a meroterpenoid, and a merodrimane from Talaromyces amestolkiae. Tetrahedron Lett. 72:153067. (PMCID: PMC8378670).
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- Ren, Y., S. Wu, J.E. Burdette, X. Cheng, and A.D. Kinghorn. 2021. Structural insights into the interactions of digoxin and Na+/K+-ATPase and other targets for the inhibition of cancer cell proliferation. Molecules 26:3672. (PMCID: PMC8234910). (Special issue in honor of academician Prof. Qiyi Xing).
- Al Subeh, Z.Y. H.A. Rafa, J.E. Burdette, J.O. Falkinham III, S.E. Hemby, and N.H. Oberlies. 2021. Three diketomorpholines from a Penicillium sp. (strain G1071). Phytochemisry 189:112830. (PMCID: PMC8292221).
- Al Subeh, Z.Y., H.A. Rafa, J.C. Obike, C.J. Pearce, M.P. Croatt, and N.H. Oberlies. 2021. Media and strain studies for the scaled production of cis-enone resorcylic acid lactones as feedstocks for semisynthesis. J. Antibiot. 74:496-507. (PMCID: PMC8313427).
- Inagaki, M., R. Iwakuma, S. Kawakami, H. Otsuka, and H.L. Rakotondraibe. 2021. Detecting and differentiating monosaccharide enantiomers by 1H NMR spectroscopy. J. Nat. Prod. 84:1863-1869. (PMCID: PMC8319160).
- Sullivan, P., A.J. Krunic, L.J. Davis, H.S. Kim, J.E. Burdette, and J. Orjala. 2021. Phormidipistatin from the cyanobacterium UIC 10484: Assessing the phylogenetic distribution of the statine pharmacophore. J. Nat. Prod. 84:2256-2264. (PMCID: PMC8403167).
- Ren, Y., S. Wu, S. Chen, J.E. Burdette, X. Cheng, and A.D. Kinghorn. 2021. Interaction of (+)-strebloside and its derivatives and Na+/K+-ATPase and other targets. Molecules 26:5675. (PMCID: PMC8467840). (Special issue in honor of Prof. Søren Brøgger Christensen).
- Muñoz Acuña, U., N. Ezzone, L.H. Rakotondraibe, and E.J. Carcache de Blanco. 2021. Activity in MCF-7 estrogen-sensitive breast cancer cells of capsicodendrin from Cinnamosma fragrans. Anticancer Res 41:5935-5944. (PMCID: PMC8750382).
- Diaz-Allen, C., R.W. Spjut, A.D. Kinghorn, and H.L. Rakotondraibe. 2021. Prioritizing natural product compounds using 1D-TOCSY NMR spectroscopy. Trends Org. Chem. 22:99-114. (PMCID: PMC9038091).
- Salvi, A., A.N. Young, A.C. Huntsman, M. Pergande, M.A, Korkmaz, R.A. Rathnayake, B.K. Mize, A.D. Kinghorn, Z. Zhang, K. Ratia, M. Schrile, J.R. Thomas, S.M. Brittain, C. Shelton, L.N. Aldrich, S.M. Cologna, J.R. Fuchs, and J.E. Burdette. 2022. PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer. Cell Death Dis. 13:45. (PMCID : PMC8748433).
- Lu, C., D. Yang, J.D. Klement, Y.L. Colson, N.H. Oberlies, C.J. Pearce, A.H. Colby, M.W. Grinstaff, H.-F. Ding, H. Shi, and K. Liu. 2022. G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes. J. Immunother. Cancer 10:e003543. (PMCID: PMC8753452).
- Flores-Bocanegra L., Z.Y. Al Subeh, J.M. Egan, T. El-Elimat, H.A. Rafa, J.E. Burdette, C.J. Pearce, R.G. Linington, and N.H. Oberlies. 2022. Dereplication of fungal metabolites by NMR-based compound networking using MADByTE. J. Nat. Prod. 85:614-624. (PMCID: PMC8957573). (Special issue in honor of Dr. William H. Gerwick).
- Al Subeh, Z.Y., A.L. Waldbusser, H.A. Raja, C.J. Pearce, K.L. Ho, M.J. Hall, M.R. Probert MR, N.H. Oberlies, and S. Hematian. 2022. Structural diversity of perylenequinones is driven by their redox behavior. J. Org. Chem. 87:2697-2710. (PMCID: PMC8898278).
- Davis, L.J., A.C. Maldonado, M. Khin, A. Krunic, J.E. Burdette, and J. Orjala. 2022. Aulosirazoles B and C from the cyanobacterium Nostoc sp. UIC 10771: Analogues of an isothiazolonaphthoquinone scaffold that activate nuclear transcription factor FOXO3a in ovarian cancer cells. J. Nat. Prod. 85:540-546. (PMCID: PMC8957594). (Special issue in honor of Dr. William H. Gerwick).
- Gubiani, J.R., D.I. Bernardi, C.C.P. De Paula, M.H.R. Seleghim, A.G. Ferreira, A.N.L. Batista, J.M. Batista, Jr., L.F.P. Oliveira, S.P. Lira, J.E. Burdette, and R.G.S. Berlinck. 2022. Absolute configuration of cytotoxic anthraquinones from a Brazilian cave soil-derived fungus, Aspergillus sp. SDC28. Arch. Pharm. 355:e2100441. (PMCID: PMC8983557).
- Yamano Y. and H.L. Rakotondraibe, 2022. Understanding the biosynthesis of paxisterol in lichen-derived Penicillium aurantiacobrunneum for production of fluorinated derivatives. Molecules 27:1641. (PMCID: PMC8911623).
- Lu, C., D. Yang, J.D. Klement, Y.L. Colson, N.H. Oberlies, C.J. Pearce, A.H. Colby, M.W. Grinstaff, Z Liu, H. Shi, HF. Ding, and K Liu. 2022. H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth. Oncogene 41:2651-2662. (PMCID: PMC9058223).
- Cank, K.B., R.A. Shepherd, S.L. Knowles, M. Rangel-Grimaldo, H.A. Raja, Z.L. Bunch, N.B. Cech, C.A. Rice, D.E. Kyle, J.O. Falkinham III, J.E. Burdette, and N.H. Oberlies. Polychlorinated cyclopentenes from a marine derived Periconia sp. (strain G1144). Phytochemistry 199:113200. (PMCID: PMC9173697).
- Freire, V.F., J.R. Gubiani, T.M. Spencer, E. Hajdu, A.G. Ferreira, D.A.S. Ferreira, E.V. de Castro Levatti, J.E. Burdette, C.H. Camargo, A.G. Tempone, and R.G.S. Berlinck. Feature-based molecular networking discovery of bromopyrrole alkaloids from the marine sponge Agelas dispar. J. Nat. Prod. 85:1340-1350. (PMCID: PMC9680911).
- Al Subeh, Z.Y., T. Li, A. Ustoyev, J.C. Obike, P.M. West, M. Khin, J.E. Burdette, C.J. Pearce, N.H. Oberlies, and M.P. Croatt. Semisynthesis of hypothemycin analogues targeting the C8−C9 diol. J. Nat. Prod. 85:2018-2025. (PMCID: PMC9677340).
- Blanco Carcache, P.J., G.D. Anaya-Eugenio, Y N. Ninh, C.E. Moore, J. Rivera-Chávez, Y. Ren, D.D. Soejarto, and A.D. Kinghorn. 2022. Cytotoxic constituents of Glycosmis ovoidea collected in Vietnam. Fitoterapia 162:105265. (PMCID: PMC9532375).
- El-Elimat T, R. Al-Qiam, J.E. Burdette, A.H. Al Sharie, M. Al-Garaibeh, and N.H. Oberlies. 2022. Homoisoflavonoids from the bulbs of Bellevalia longipes and an assessment of their potential cytotoxic activity. Phytochemistry 203:1133443 (PMCID: PMC9795560).
- Mirtallo Ezzone, N.P., G.D. Anaya-Eugenio, E. Mekuria Addo, Y. Ren, A.D. Kinghorn, and E.J. Carcache de Blanco. 2022. Effects of cochorususoside C on NF-kappaB and PARP-1 molecular targets and toxicity profile in zebrafish. Int. J. Mol. Sci. 23:14546. (PMCID: PMC9739208).
- Caesar LK, Butun FA, Robey MT, Ayon NJ, Gupta R, Dainko D, Bok JW, Nickles G, Stankey RJ, Johnson D, Mead D, Cank KB, Earp CE, Raja HA, Oberlies NH, Keller NP, Kelleher NL. Correlative metagenomics of 100 fungi reveals metabolite-gene cluster pairs. Nat Chem Biol.2023 Jul; 19(7):846-854. E-pub 2023 Mar 6. PMCID: PMC10313767.
- Subeh ZY, Flores-Bocanegra L, Raja HA, Burdette JE, Pearce CJ, Oberlies NH. Embellicines C-E, macrocyclic alkaloids with a cyclopenta[b]fluorene ring system from the fungus Saroclasdium J Nat Prod. 2023 Mar 24; 86(3):596-603. E–pub 2023 Mar 8. PMCID: PMC10043936. (Special issue in honor of Prof. Mary J. Garson).
- Kaweesa EN, Bazioli JM, Pierre, HC, Lantvit DD, Kulp SK, Hill KL, Phelps MA, Coss CC, Fuchs JR, Pearce CJ, Oberlies NH, Burdette JE. Exploration of verticillins in high-grade serous ovarian cancer and evaluation of multiple formulations in preclinical in vivo and in vivo models. Mol Pharmaceutics. 2023 Jun; 20(6):3049-3059. E-pub 2023 May 8. PMCID: PMC10405366.
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- Kyle KE, Puckett SP, Caraballo-Rodríguez AM, Rivera-Chávez J, Samples RM, Earp CA, Raja HA, Pearce CJ, Ernst M, van der Hooft JJJ, Adams ME, Oberlies NH, Dorrestein PC, Klassen JL, Balunas MP. Trachymyrmex septentrionalis ants promote garden hygiene using Trichoderma-derived metabolic clues. Proc Natl Acad Sci USA. 2023 Jun; 20:120(5):e219373120. E-pub 2023 Jun 15. PMCID:PMC10288546.
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