Graduate Students
The Nakanishi lab is looking for highly motivated graduate students. We take multiple approaches, including biochemistry, molecular biology, and structural biology, to understand how microRNAs and Argonaute proteins regulate gene expression whose dysregulation causes neurodevelopmental diseases and cancers. For those interested in our research, please contact Dr. Nakanishi (nakanishi.9@osu.edu)!

Technician Position: Apply from HERE!
We are looking for a new technician. The main job is to 1) express and purify recombinant proteins in insect cells, human cells, and E. coli, 2) maintain the cell culture, and 3) clone genes. Please contact nakanishi.9@osu.edu).

Bioinformatician Position (Research Associate / Postdoc)
Detailed job description:
We are seeking a highly motivated bioinformatics scientist to work in our research group at The Ohio State University (OSU). Our research is focused on a new class of small non-coding RNAs that we discovered. We use next-generation sequencing-based technologies along with molecular and cellular biochemistry to identify the small RNAs and their targets, characterizing their functions in human health and disease. The successful applicant will be involved in the computational analysis and interpretation of these data. She/he will create workflows based on existing tools and develop new analysis methodologies to translate novel data into biological discoveries.

The successful candidate is expected to have expertise in bioinformatics and apply it to multiple projects in close collaboration with experimentalists who produce large data. The position provides a unique opportunity to acquire practical data science skills in high demand and to develop a career in cutting-edge bioinformatics services and infrastructures. The position will be supported by a senior computational biology collaborator at OSU and will be complemented by interactions with a network of bioinformaticians. OSU and the neighboring Ohio Supercomputer Center provide excellent computational and scientific infrastructure in support of the position.

Duties Description:
Uses information technology, scientific computing, and bioinformatics to drive analysis of biological sequence data sets. Adapts existing workflows and algorithms to fit research analysis needs. Work closely with experimentalists to plan, develop, and execute data analysis and management tasks. Contributes to manuscript preparation
10%: Trains graduate students and postdocs in bioinformatics.
5%: Serves as computational infrastructure administrator for the lab.

Minimum education requirement:
Applicants should have a university degree in bioinformatics, biostatistics, biophysics, computer science, or related fields (Bachelors or Masters) with at least 1 year of relevant professional experience in bioinformatics development and computational analysis (or equivalent combination of education and experience). Qualified candidates with a Ph.D. degree can be considered for a post-doctoral research associate position.

Major #1: Bioinformatics,
Major #2: Biostatistics, Biophysics, Computer Science

The individual must be motivated, dedicated, and must possess excellent analytical skills. Educational background or practical knowledge in analyzing large datasets, working in Linux environments, and good programming skills are required. Prior experience with scripting languages (e.g., Python, Perl) is necessary. Knowledge of software tool development, the statistical programming language R, and next-generation sequencing (NGS) analyses is advantageous. A general understanding of biological questions will help to communicate with other scientists. The candidate should be able to work independently and integrate well in a team environment. Strong communication skills, as well as the ability to work in an interdisciplinary team, are essential.

Contact information:
Please email Dr. Kotaro Nakanishi (nakanishi.9@osu.edu).