News

Oct. 2020 Huaqun Zhang joined our lab as a Postdoc.  Welcome to the Nakanishi lab!

Oct. 2020 GeunYoung Sim presents our discovery of the different activation mechanisms of human AGO2 and AGO3 at the Rustbelt RNA Meeting 2020 in Cleaveland.

Sep. 2020 Audrey Kehling joined our lab as a Research Assistant.  Welcome back, Audrey!

Sep. 2020 Our work on Argonaute2 and Argoanute3 are catalytically activated by different lengths of guide RNA is accepted in Proc. Natl. Acad. Sci. U.S.A.

Jul. 2020 We posted our recent study of AGO3 activation by very short guide RNAs on bioRxiv.

Jul. 2020 We open two NIH-funded postdoc positions (see opportunities).

Jul 202o We were awarded a new NIGMS-funded R1 grant entitled “Structural and molecular basis for cityRNA (cleavage-inducing tiny RNA)-directed RNA cleavage by AGO3.”

Jun. 2020 GeunYoung was awarded a Center for RNA Biology Fellowship. Congratulations!

Nov. 2019 We are looking for a technician (see opportunities).

Nov. 2019 We are looking for a postdoctoral fellow (see opportunities).

Nov. 2019 Mi Seul passed her defense.  Congratulations!

Nov. 2019 Our recent study was highlighted in NECAT News.

Nov. 2019 Kotaro presents Studies and applications of Argonaute proteins at Cincinnati Children Hospital Cancer Center.

Oct. 2019 Mi Seul Park presents our discovery of water molecules inside Argonaute protein at the Rustbelt RNA Meeting 2019 in Cleaveland.

Oct. 2019 Madhoolika Bisht (Mol. Gen), Ian Price (OSBP), and Christina Ross (MCDB) started their rotation.  Welcome to the Nakanishi lab!

Jul. 2019 Our work on Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters is online in Molecular Cell.

Jul. 2019 Kotaro presents Structure and Mechanism of Human Argonaute Paralogs at the RNA Japan 2019 in Tokyo, Japan.

Jul. 2019 Kotaro presents Studies and applications of Argonaute protein at Department of Biological Sciences, The University of Tokyo.

Jun. 2019 Mi Seul Park presents her research at the RNA2019 in Krakow, Poland.

May. 2019 Kotaro is tenured and promoted to Associate Professor.

May. 2019 Seema Nath joined the group.  Welcome to the Nakanishi lab!

Mar. 2019 Mi Seul Park is the recipient of a travel fellowship of the RNA2019 in Krakow, Poland.

Mar. 2019 GeunYoung Sim (MCDB) joined the group.  Welcome to the Nakanishi lab!

Feb. 2019 Danny left for his new place. Good luck with your postdoctoral training at The Rockefeller University!

Dec. 2018 We are looking for a postdoctoral fellow (see opportunities).

Nov. 2018 Danny passed his defense.  Congratulations!

Oct. 2018 Aaron Natarelli joined the group as a research assistant.  Welcome to the Nakanishi lab!

Oct. 2018. Kotaro presents Anatomy of RNAi effector complex and the application to a programmable RNA restriction enzyme at Biological Chemistry Seminar Program in The Johns Hopkins University School of Medicine.

Oct. 2018. Audrey  Kehling will present our recent study about human Argonaute proteins in the Rustbelt RNA Meeting 2018.

Oct. 2018. Kotaro presents Anatomy of RNAi effector complex and the application to a programmable RNA restriction enzyme at Biochemistry and Molecular Biology Faculty Seminar Series in Indiana University School of Medicine.

Oct. 2018 Geunyoung Sim (MCDB) and Janet Milton (MCDB) started their rotation.  Welcome to the Nakanishi lab!

Sep. 2018. Kotaro presents Anatomy of RNAi effector complex and the application to a programmable RNA restriction enzyme at Molecular & Cell Biology seminar in the Uniformed Services University of the Health Sciences.

Sep. 2018. Kotaro presents Anatomy of RNAi effector complex and the application to a programmable RNA restriction enzyme at Biochemistry and Molecular Biology seminar in Wright State University.

Sep. 2018. Pablo Vidal Souza (MCDB) and Jamison Law (OSBP) started their rotation. Welcome to the Nakanishi lab!

Jul. 2018. Md Shah Alam (CBC) started his rotation. Welcome to the Nakanishi lab!

Jul. 2018. Our recent paper about DISC was nominated as a hot paper at Oligonucleotide Therapeutic Society.

Jun. 2018. Our work on Argonaute-based programmable RNase is online in Nucleic Acids Research. This DNA-induced slicing complex, DISC, cleaves highly-structured RNAs.

Jun. 2018. Mi Seul was awarded a 2-year Pelotonia fellowship.

Apr. 2018. Danny Dayeh is the recipient of the Robin C. Burrell Memorial Fund.

Mar. 2018. Danny Dayeh will speak about our Argonaute-based RNA restriction enzyme at the RNA2018 in Berkeley.

Mar. 2018. Our AGO3 paper was one of NAR Top Articles – Molecular Biology – in Feb. 2018.

Mar. 2018. Mi Seul Park is the recipient of a travel fellowship of the Regulatory & Non-Coding RNAs in the Cold Spring Harbor Laboratory.

Mar. 2018. Our work on the selectivity of RNA target cleavage by Argonaute is accepted in Journal of Biological Chemistry.  A possible convergent functional evolution with Cas9 is discussed.

Mar. 2018. Danny Dayeh is the recipient of a travel fellowship of the RNA2018 in Berkeley.

Nov. 2017. Our AGO3 paper is one of the 5 most-read papers of Nucleic Acids Research as of Nov. 10.

Nov. 2017. Argonaute Proteins, Methods in Molecular Biology (Springer) edited by Kotaro Nakanishi with Dr. Katsutomo Okamura (Temasek Lifesciences Laboratory, Singapore)

Oct. 2017. For those interested in joining our research group, please visit the opportunity page!

Oct. 2017. Danny Dayeh is the recipient of an outstanding poster award at the Rustbelt RNA Meeting.

Oct. 2017. Mi Seul Park spoke our AGO3 work at the Rustbelt RNA Meeting.

Oct. 2017. Our work on human Argonaute3 is published in Nucleic Acids Research.

Oct. 2017. Mi Seul Park is the recipient of a Burrell Memorial Fund Travel Award.

Jun. 2017. Mi Seul Park is the recipient of a travel fellowship of the RNA Society Meeting in Prague.