Apr. 2024 Kotaro presents our work at the Laboratory for Biochemistry and Molecular Biology Seminar, Bethesda.
Nov. 2023 Our latest review on the endonuclease activity of AGOs published in JBC.
Nov. 2023 We defined the length boundary between tyRNAs and miRNAs/siRNAs in Scientific Reports.
Nov. 2023 Kotaro presents our work at National Cancer Institute RNA Biology Laboratory Seminar, Frederick.
Oct. 2023 Andrew Savidge received a Poster Award at the Rustbelt RNA Meeting 2023! Congrats Andrew!
Oct. 2023 Huaqun, GeunYoung, and Andrew present their work at the Rustbelt RNA Meeting, Michigan.
Oct. 2023 Evan Liu joined our lab as a CBC rotation student. Welcome to the Nakanishi lab!
Oct. 2023 Andrew presented his work at the CMBP Monthly Meeting.
Oct. 2023 Kotaro presented our work at Structural Biology Seminar at Case Western Reserve University, Cleveland.
Sep. 2023 Kotaro presented our work at Structure, Function and Dynamics International Conference, Waikiki.
Sep. 2023 Kotaro presented our work at University of Florida, Gainesville.
Aug. 2023 Chin Wang joined our lab as a MCDB rotation student. Welcome to the Nakanishi lab!
Aug. 2023 Kotaro presents our work at Chemistry & Biochemistry Bioseminar, Columbus.
Aug. 2023 Cameron passed his candidacy exam. Congrats!
Aug. 2022 Uttam Sharma joined the Nakanishi lab!! Welcome!
Jul. 2023 Andrew passed his candidacy exam. Congrats!
Jul. 2022 Vishal Adhav joined the Nakanishi lab!! Welcome!
Jul. 2023 Our collaborative work on the cryo-EM structure of the SPARTA-RNA-DNA complex in Nature.
Jul. 2023 Our team (Co-PI) was awarded a President’s Research Excellence Accelerator Grant!
Jun. 2023 A new NIGMS Equipment Grant was funded!
May 2023 Audrey Kehling was promoted to Research Senior Tech. Congrats!
May 2023 Andrew Savidge received the Best Poster Presentation at the IGP symposium. Congrats!
May 2023 A new NIH R21 grant was funded! We did well!!
May 2023 Andrew and Cameron present their works at the CMBP/CRB Symposium. Kotaro gives a talk as a local speaker.
Apr. 2023 Kotaro presents our work at RNA-mediated gene regulation 2023 in Barbados.
Feb. 2023 We opened a postdoc position understanding the roles of tiny RNAs in human diseases! Please see Opportunity.
Jan. 2023 We opened a postdoc position elucidating the structural basis for the target recognition by tiny RNA-bound human Argonaute proteins! Please see Opportunity.
Dec. 2022 Our collaborative work on the significance of Argonaute phosphorylation for miRNA binding was published in Cell Reports.
Dec. 2022 Our discovery of the tiny RNA biogenesis was published in PNAS.
Nov. 2022 We are looking for motivated postdoc candidates who have expertise in confocal microscopy (our lab has our own microscope!) and want to learn X-ray crystallography and/or cryo-EM. We are particularly interested in candidates with neuronal differentiation or viral infection background.
Oct. 2022 Our discovery of the tiny RNA biogenesis was posted to bioRxiv.
Oct. 2022 Huaqun Zhang and GeunYoung give their oral and poster presentations at the Rustbelt RNA Meeting.
Oct. 2022 Kotaro presents our recent works at microRNA Symposium 2022 at University of Illinois Chicago.
Aug. 2022 Olivia Roumaya joined our lab as an OSBP rotation student, Welcome to the Nakanishi lab!
Aug. 2022 Kotaro presents our recent works at the Argonaute Meeting at University of Regensburg.
Jul. 2022 Our NIH R01 was officially renewed!
Jun 2021 Kotaro’s review article on four human Argonaute proteins was published in Nucleic Acids Research.
Jun. 2022 GeunYoung Sim and Kotaro presented our recent works at the RNA Society Meeting 2022.
May 2022 Andrew Savidge was awarded a CMBP Fellowship for the 2022-2023 academic year. Congrats Andrew!
May 2022 Kotaro spoke about our recent works at the IGP.
May 2022 Kotaro presented our recent work at the Regulatory & Non-coding RNA (CSHL Meeting).
Mar. 2022 GeunYoung Sim was the recipient of an MCDB Travel Award to attend the RNA Society Meeting 2022. Congrats!
Mar. 2022 GeunYoung Sim was the recipient of a Center for RNA Biology Travel Fellowship to attend the RNA Society Meeting 2022. Congrats!
Mar 2022 Andrew Savidge and Cameron Divoky joined the Nakanishi lab!! Welcome!
Feb 2022 GeunYoung Sim had her Center for RNA Fellow Presentation.
Jan 2022 Andrew Savidge joined our lab as an OSBP rotation student. Welcome to the Nakanishi lab!
Dec 2021 Mi Seul Park, an alumnus of the Nakanishi lab, was awarded a new early K99/R00 Award. Congrats!
Nov 2021 Kotaro’s minireview article on tiny RNAs was accepted in Front. Mol. Biosci.
Nov 2021 Kotaro gives a talk at University of California, Riverside.
Nov 2021 Madalyn Moore and Shivam Chaubey joined our lab as CBC rotation students. Welcome to the Nakanishi lab!
Oct 2021 Niyi Adelakun and Yi-Hui Wang joined our lab as OSBP rotation students. Welcome to the Nakanishi lab!
Sep 2021 Jackson Secor joined our lab as a Research Assistant. Welcome!
Sep 2021 Kotaro is a co-organizer of the Rustbelt RNA Meeting 2021.
Aug 2021 Cameron Divoky joined our lab as an OSBP rotation student. Welcome to the Nakanishi lab!
Aug 2021 GeunYoung and Kotaro attended Pelotonia Bike Race.
May 2021 GeunYoung presented our work on cityRNAs at the RNA Society Meeting 2021.
May 2021 GeunYoung was awarded a Poster Prize at the IGP Symposium. Congratulations!
May 2021 We open a bioinformatician position (see opportunities).
May 2021 GeunYoung Sim was awarded a 2-year Pelotonia fellowship. Congrats GeunYoung!
Feb. 2021 Nipun Malhotra joined our lab as a Research Assistant. Welcome to the Nakanishi lab!
Jan. 2021 We helped the interpretation of the Med13 structure that was published in Science Advances.
Jan. 2021 GeunYoung passed her candidacy exam. Congratulations!
Jan. 2021 Divyaa received a professional development award. Congratulations!
Dec. 2020 Divyaa Bhagdikar joined our lab as a Postdoc. Welcome to the Nakanishi lab!
Oct. 2020 Our discovery of AGO3 activation by cityRNAs was published in PNAS.
Oct. 2020 GeunYoung Sim received an Excellent Oral Presentation Award at the RRM2020. Congratulations!
Oct. 2020 Huaqun Zhang joined our lab as a Postdoc. Welcome to the Nakanishi lab!
Oct. 2020 GeunYoung Sim presents our discovery of the different activation mechanisms of human AGO2 and AGO3 at the Rustbelt RNA Meeting 2020 in Cleaveland.
Sep. 2020 Audrey Kehling joined our lab as a Research Assistant. Welcome back, Audrey!
Sep. 2020 Our work on Argonaute2 and Argoanute3 are catalytically activated by different lengths of guide RNA is accepted in Proc. Natl. Acad. Sci. U.S.A.
Jul. 2020 We posted our recent study of AGO3 activation by very short guide RNAs on bioRxiv.
Jul. 2020 We open two NIH-funded postdoc positions (see opportunities).
Jul 202o We were awarded a new NIGMS-funded R01 grant entitled “Structural and molecular basis for cityRNA (cleavage-inducing tiny RNA)-directed RNA cleavage by AGO3.”
Jun. 2020 GeunYoung was awarded a Center for RNA Biology Fellowship. Congratulations!
Nov. 2019 We are looking for a technician (see opportunities).
Nov. 2019 We are looking for a postdoctoral fellow (see opportunities).
Nov. 2019 Mi Seul passed her defense. Congratulations!
Nov. 2019 Our recent study was highlighted in NECAT News.
Nov. 2019 Kotaro presents Studies and applications of Argonaute proteins at Cincinnati Children Hospital Cancer Center.
Oct. 2019 Mi Seul Park presents our discovery of water molecules inside Argonaute protein at the Rustbelt RNA Meeting 2019 in Cleaveland.
Oct. 2019 Madhoolika Bisht (Mol. Gen), Ian Price (OSBP), and Christina Ross (MCDB) started their rotation. Welcome to the Nakanishi lab!
Jul. 2019 Our work on Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters is online in Molecular Cell.
Jul. 2019 Kotaro presents Structure and Mechanism of Human Argonaute Paralogs at the RNA Japan 2019 in Tokyo, Japan.
Jul. 2019 Kotaro presents Studies and applications of Argonaute protein at Department of Biological Sciences, The University of Tokyo.
Jun. 2019 Mi Seul Park presents her research at the RNA2019 in Krakow, Poland.
May. 2019 Kotaro is tenured and promoted to Associate Professor.
May. 2019 Seema Nath joined the group. Welcome to the Nakanishi lab!
Mar. 2019 Mi Seul Park is the recipient of a travel fellowship of the RNA2019 in Krakow, Poland.
Mar. 2019 GeunYoung Sim (MCDB) joined the group. Welcome to the Nakanishi lab!
Feb. 2019 Danny left for his new place. Good luck with your postdoctoral training at The Rockefeller University!
Dec. 2018 We are looking for a postdoctoral fellow (see opportunities).
Nov. 2018 Danny passed his defense. Congratulations!
Oct. 2018 Aaron Natarelli joined the group as a research assistant. Welcome to the Nakanishi lab!
Oct. 2018. Kotaro presents Anatomy of RNAi effector complex and the application to a programmable RNA restriction enzyme at Biological Chemistry Seminar Program in The Johns Hopkins University School of Medicine.
Oct. 2018. Audrey Kehling will present our recent study about human Argonaute proteins in the Rustbelt RNA Meeting 2018.
Oct. 2018. Kotaro presents Anatomy of RNAi effector complex and the application to a programmable RNA restriction enzyme at Biochemistry and Molecular Biology Faculty Seminar Series in Indiana University School of Medicine.
Oct. 2018 Geunyoung Sim (MCDB) and Janet Milton (MCDB) started their rotation. Welcome to the Nakanishi lab!
Sep. 2018. Kotaro presents Anatomy of RNAi effector complex and the application to a programmable RNA restriction enzyme at Molecular & Cell Biology seminar in the Uniformed Services University of the Health Sciences.
Sep. 2018. Kotaro presents Anatomy of RNAi effector complex and the application to a programmable RNA restriction enzyme at Biochemistry and Molecular Biology seminar in Wright State University.
Sep. 2018. Pablo Vidal Souza (MCDB) and Jamison Law (OSBP) started their rotation. Welcome to the Nakanishi lab!
Jul. 2018. Md Shah Alam (CBC) started his rotation. Welcome to the Nakanishi lab!
Jul. 2018. Our recent paper about DISC was nominated as a hot paper at Oligonucleotide Therapeutic Society.
Jun. 2018. Our work on Argonaute-based programmable RNase is online in Nucleic Acids Research. This DNA-induced slicing complex, DISC, cleaves highly-structured RNAs.
Jun. 2018. Mi Seul was awarded a 2-year Pelotonia fellowship.
Apr. 2018. Danny Dayeh is the recipient of the Robin C. Burrell Memorial Fund.
Mar. 2018. Danny Dayeh will speak about our Argonaute-based RNA restriction enzyme at the RNA2018 in Berkeley.
Mar. 2018. Our AGO3 paper was one of NAR Top Articles – Molecular Biology – in Feb. 2018.
Mar. 2018. Mi Seul Park is the recipient of a travel fellowship of the Regulatory & Non-Coding RNAs in the Cold Spring Harbor Laboratory.
Mar. 2018. Our work on the selectivity of RNA target cleavage by Argonaute is accepted in Journal of Biological Chemistry. A possible convergent functional evolution with Cas9 is discussed.
Mar. 2018. Danny Dayeh is the recipient of a travel fellowship of the RNA2018 in Berkeley.
Nov. 2017. Our AGO3 paper is one of the 5 most-read papers of Nucleic Acids Research as of Nov. 10.
Nov. 2017. Argonaute Proteins, Methods in Molecular Biology (Springer) edited by Kotaro Nakanishi with Dr. Katsutomo Okamura (Temasek Lifesciences Laboratory, Singapore)
Oct. 2017. For those interested in joining our research group, please visit the opportunity page!
Oct. 2017. Danny Dayeh is the recipient of an outstanding poster award at the Rustbelt RNA Meeting.
Oct. 2017. Mi Seul Park spoke our AGO3 work at the Rustbelt RNA Meeting.
Oct. 2017. Our work on human Argonaute3 is published in Nucleic Acids Research.
Oct. 2017. Mi Seul Park is the recipient of a Burrell Memorial Fund Travel Award.
Jun. 2017. Mi Seul Park is the recipient of a travel fellowship of the RNA Society Meeting in Prague.