Publications

  1. Miles WO*, Lembo A, Volorio A, Brachtel E, Tian B, Sgroi D, Provero P and Dyson NJ*. Alternative polyadenylation in triple-negative breast tumors allows NRAS and c-JUN to bypass PUMILIO post-transcriptional regulation. Cancer Research, Sep 2015, ACCEPTED. *Co-corresponding author.
  2. Miles WO, Bourdeaux J, Lepesant J, Texier M, Kerenyi MA, Nakakido M, Hamamoto R, Orkin SH, Dyson NJ and Di Stefano L. Identification of a feedback regulatory loop between dLsd1 and LSD2 and the Pumilio post-transcriptional repressor complex. Molecular Cell Biology, Nov 2015, 36(20). PMID: 26438601.
  3. Nicolay BN, Danielian PS, Kottakis F, Lapek JD Jr, Sanidas I, Miles WO, Dehnad M, Tschöp K, Gierut JJ, Manning AL, Morris R, Haigis K, Bardeesy N, Lees JA, Haas W, Dyson NJ. Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation. Genes and Development, Aug 2015, PMID: 26314710.
  4. Miles WO and Dyson NJ. RB-loss puts focus on Myc. Nature Cell Biology, Jul 2015, 31; 17 (8):968-9. PMID26239529.
  5. Miles WO, Korenjak M, Dyer M, Provero P and Dyson NJ. Post-transcriptional regulation by NANOS counterbalances E2F activity to suppress apoptotic responses in pRb deficient cells. EMBO Journal, Oct 2014, 33(19):2201-15. PMC4282507
  6. Miles WO, Tschöp K, Herr A, Ji JY, Dyson, NJ. Pumilio facilitates miRNA regulation of the E2F3 oncogene. Genes and Development, Feb 2012 26(4): p356-368. PMC3289884.
  7. Miles WO, Dyson, NJ and Walker, JA. Modeling tumor invasion and metastasis in Drosophila. Disease, Models and Mechanisms, Nov 2011. 4(6): p. 753-761. PMC3209645.
  8. Ji, JY, Miles WO, Korenjak M, Zheng Y and Dyson NJ. In Vivo Regulation of E2F1 by Polycomb Group Genes in Drosophila. Genes, Genomes and Genetics, Dec 2012. 2: p1651-1660. PMC3516486.
  9. Miles WO, Jaffray E, Campbell SG, Takeda S, Bayston LJ, Basu SP, Li M, Raftery LA, Ashe MP, Hay RT, Ashe HL. Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo. Genes and Development, Sep 2008 15; 22(18):2578-90. PMC2546696.