Publications

Lenz Lab publications:

Maternal allergic inflammation in rats impacts the offspring perinatal neuroimmune milieu and the development of social play, locomotor behavior, and cognitive flexibility. Breach MR, Dye CN, Joshi A, Platko S, Gilfarb RA, Krug AR, Franceschelli DV, Galan A, Dodson CM, Lenz KM. Brain Behav Immun. 2021 Mar 30:S0889-1591(21)00155-0. doi: 10.1016/j.bbi.2021.03.025. Online ahead of print. PMID: 33798637

Microglia Regulate Cell Genesis in a Sex-dependent Manner in the Neonatal Hippocampus.Nelson LH, Peketi P, Lenz KM. Neuroscience. 2021 Jan 15;453:237-255. doi: 10.1016/j.neuroscience.2020.10.009. Epub 2020 Oct 28.PMID: 33129890

Sex differences in the effects of early life stress exposure on mast cells in the developing rat brain. Joshi A, Page CE, Damante M, Dye CN, Haim A, Leuner B, Lenz KM.Horm Behav. 2019 Jul;113:76-84. doi: 10.1016/j.yhbeh.2019.04.012. Epub 2019 May 10.PMID: 31054843

Neuroimmunology of the female brain across the lifespan: Plasticity to psychopathology. Barrientos RM, Brunton PJ, Lenz KM, Pyter L, Spencer SJ.Brain Behav Immun. 2019 Jul;79:39-55. doi: 10.1016/j.bbi.2019.03.010. Epub 2019 Mar 11.PMID: 30872093

Small cells with big implications: Microglia and sex differences in brain development, plasticity and behavioral health. Nelson LH, Saulsbery AI, Lenz KM.Prog Neurobiol. 2019 May;176:103-119. doi: 10.1016/j.pneurobio.2018.09.002. Epub 2018 Sep 5.PMID: 30193820

Mast Cells in the Developing Brain Determine Adult Sexual Behavior. Lenz KM, Pickett LA, Wright CL, Davis KT, Joshi A, McCarthy MM.J Neurosci. 2018 Sep 12;38(37):8044-8059. doi: 10.1523/JNEUROSCI.1176-18.2018. Epub 2018 Aug 7.PMID: 30093566

Microglia and Beyond: Innate Immune Cells As Regulators of Brain Development and Behavioral Function. Lenz KM, Nelson LH.Front Immunol. 2018 Apr 13;9:698. doi: 10.3389/fimmu.2018.00698. eCollection 2018.PMID: 29706957

Neuroimmunology and neuroepigenetics in the establishment of sex differences in the brain. McCarthy MM, Nugent BM, Lenz KM. Nat Rev Neurosci. 2017 Aug;18(8):471-484. doi: 10.1038/nrn.2017.61. Epub 2017 Jun 22.PMID: 28638119

Sex differences in microglial phagocytosis in the neonatal hippocampus. Nelson LH, Warden S, Lenz KM. Brain Behav Immun. 2017 Aug;64:11-22. doi: 10.1016/j.bbi.2017.03.010. Epub 2017 Mar 22.PMID: 28341582

The immune system as a novel regulator of sex differences in brain and behavioral development. Nelson LH, Lenz KM. J Neurosci Res. 2017 Jan 2;95(1-2):447-461. doi: 10.1002/jnr.23821.PMID: 27870450
A survey of neuroimmune changes in pregnant and postpartum female rats. Haim A, Julian D, Albin-Brooks C, Brothers HM, Lenz KM, Leuner B.Brain Behav Immun. 2017 Jan;59:67-78. doi: 10.1016/j.bbi.2016.09.026. Epub 2016 Sep 26.PMID: 27686844

Microglia depletion in early life programs persistent changes in social, mood-related, and locomotor behavior in male and female rats. Nelson LH, Lenz KM. Behav Brain Res. 2017 Jan 1;316:279-293. doi: 10.1016/j.bbr.2016.09.006. Epub 2016 Sep 6.PMID: 27613230

Brain feminization requires active repression of masculinization via DNA methylation. Nugent BM, Wright CL, Shetty AC, Hodes GE, Lenz KM, Mahurkar A, Russo SJ, Devine SE, McCarthy MM. Nat Neurosci. 2015 May;18(5):690-7. doi: 10.1038/nn.3988. Epub 2015 Mar 30.PMID: 25821913
A starring role for microglia in brain sex differences. Lenz KM, McCarthy MM.Neuroscientist. 2015 Jun;21(3):306-21. doi: 10.1177/1073858414536468. Epub 2014 May 28.PMID: 24871624
Microglia are essential to masculinization of brain and behavior. Lenz KM, Nugent BM, Haliyur R, McCarthy MM. J Neurosci. 2013 Feb 13;33(7):2761-72. doi: 10.1523/JNEUROSCI.1268-12.2013.PMID: 23407936