REPRESENTATIVE PUBLICATIONS

Ayoub CA, Wagner CS, Kuret J. Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer’s disease. PLoS Genet. 2023 Mar;19(3):e1010681. doi: 10.1371/journal.pgen.1010681. eCollection 2023 Mar. PubMed PMID: 36972319; PubMed Central PMCID: PMC10079065.

Jimenez-Harrison D, Huseby CJ, Hoffman CN, Sher S, Snyder D, Seal B, Yuan C, Fu H, Wysocki V, Giorgini F, Kuret J. DJ-1 Molecular Chaperone Activity Depresses Tau Aggregation Propensity through Interaction with Monomers. Biochemistry. 2023 Mar 7;62(5):976-988. doi: 10.1021/acs.biochem.2c00581. Epub 2023 Feb 22. PubMed PMID: 36813261; PubMed Central PMCID: PMC9997487.

Yang J, Agnihotri MV, Huseby CJ, Kuret J, Singer SJ. A theoretical study of polymorphism in VQIVYK fibrils. Biophys J. 2021 Apr 20;120(8):1396-1416. doi: 10.1016/j.bpj.2021.01.032. Epub 2021 Feb 9. PubMed PMID: 33571490; PubMed Central PMCID: PMC8105716.

Huseby CJ, Bundschuh R, Kuret J. The role of annealing and fragmentation in human tau aggregation dynamics. J Biol Chem. 2019 Mar 29;294(13):4728-4737. doi: 10.1074/jbc.RA118.006943. Epub 2019 Feb 11. PubMed PMID: 30745358; PubMed Central PMCID: PMC6442056.

Funk KE, Thomas SN, Schafer KN, Cooper GL, Liao Z, Clark DJ, Yang AJ, Kuret J. Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity. Biochem J. 2014 Aug 15;462(1):77-88. doi: 10.1042/BJ20140372. PubMed PMID: 24869773; PubMed Central PMCID: PMC4292886.

Cisek K, Jensen JR, Honson NS, Schafer KN, Cooper GL, Kuret J. Ligand electronic properties modulate tau filament binding site density. Biophys Chem. 2012 Aug-Sep;170:25-33. doi: 10.1016/j.bpc.2012.09.001. Epub 2012 Sep 11. PubMed PMID: 23072817; PubMed Central PMCID: PMC3488124.

Funk KE, Mrak RE, Kuret J. Granulovacuolar degeneration (GVD) bodies of Alzheimer’s disease (AD) resemble late-stage autophagic organelles. Neuropathol Appl Neurobiol. 2011 Apr;37(3):295-306. doi: 10.1111/j.1365-2990.2010.01135.x. PubMed PMID: 20946470; PubMed Central PMCID: PMC3037976.

Complete List of Published Work in MyBibliography