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Undergraduate Research Assistant at Indiana University School of Medicine

During the summers of 2018 and 2019 I had the opportunity to work as an Undergraduate Research Assistant at Indiana University School of Medicine in the Department of Radiation Oncology. The Primary Investigator of this lab is Joe Dynlacht, PhD. In his lab we studied the effects of chemotherapeutic agents that are not toxic to normal tissue at 37 °C when administered systemically, but can become toxic under local hyperthermia treatment. The agents I worked with were various metalloenediynes, including an iron sulfate enediyne and a platinated modified metalloenediyne. I performed experiments where I administered the agent to cells at different concentrations and tested the effects it had on those cells at 37 °C and 42.5 °C. The cells I worked with were MDA-231 (breast) and U1 (melanoma) human cancer cell lines. Through this experience I learned valuable skills including basic and sterile lab techniques, and working with mice in a laboratory setting. I even had the opportunity to co-author an article that was submitted to the Radiation Research journal in May 2019 called “Enhancement of cytotoxicity of enediyne compounds by hyperthermia: Effects of various metal co-factor complexes on tumor cells.”

STEM Exploration & Engagement Scholars

During my first two years at Ohio State, I participated in and completed the STEM Exploration & Engagement Scholars program. I lived in a collaborative learning community with other scholars during the 2017-2018 school year, which allowed me to meet students of different STEM disciplines. As a scholars program, we explored many areas of science, engineering, technology and math. Each student was allowed to pursue his or her personal interests by completing and presenting a capstone project. My capstone project was about my research experience at the Indiana University School of Medicine (see Work Experience). Through this experience I experienced an academic research setting, I learned basic and sterile lab techniques, and I had the opportunity to co-author an article that was submitted to the Radiation Research journal in May 2019.

About Me

Hello! My name is Laura Kryah, and I am a fourth year Chemical Engineering student at The Ohio State University pursuing a B.S. in Chemical and Biomolecular Engineering with a minor in Mathematics. Here on Ohio State’s campus I am involved in BuckeyeThon serving as a Team Captain and a member of the Diversity, Equity and Inclusion Task Force. I am also a founding member of Omega Chi Epsilon, an honor society for chemical engineering students. During my first two years at Ohio State I also completed the STEM Exploration and Engagement Scholars Program. During the summers of 2018 and 2019 I worked as an Undergraduate Research Assistant at the Indiana University School of Medicine Department of Radiation Oncology. When I am not in school or working, I enjoy hanging out with friends, spending time outside, and traveling to new places.

Omega Chi Epsilon (OXE)

In the spring of 2019 I began working with other distinguished chemical engineering students to form the Ohio State chapter of Omega Chi Epsilon, an chemical engineering honor society. As a founding member, I helped create the core values and goals of the organization. I serve as the Recruitment Chair, so my main responsibilities include reaching out to potential new members for the organization, coordinating the information sessions for the new members, and planning the induction ceremonies each semester. This experience has allowed me to improve my leadership, communication, and organization skills.