Tractography-based VIM targeting

With a goal for delivering precise surgical therapy, we developed a novel methodology for stereotactic targeting during tremor surgery using diffusion tensor imaging. We also performed microelectrode recordings within the imaging-defined surgical target to better understand the physiological significance of neuroimaging findings.

Relevant references –

• 1. Krishna, V., Sammartino, F., Agrawal, P., Changizi, B. K., Bourekas, E., Knopp, M. V., & Rezai, A. (2018). Prospective tractography-based targeting for improved safety of focused ultrasound thalamotomy. Neurosurgery.
  2. Sammartino, F., Krishna, V., King, N. K. K., Lozano, A.M., Hodaie, M. (2016) Tractography-based VIM targeting: Novel methodology and intraoperative validation. Mov Dis (2016)
  3. King, N. K. K., Krishna, V., Basha, D., Elias, G., Sammartino, F., Hodaie, M., Lozano, A. M., Hutchison, W. (2016) Microelectrode recording findings within tractography-defined VIM. J Neurosurg (2016)