Professor, Albert Einstein College of Medicine
Dr. Fine’s professional interests have centered on non-invasive measurement of physiologic and molecular function, especially with radiotracer technology. This was applied to the heart and especially to measurement of kidney function and its role and contribution to hypertension; and more recently has focused on radiotracers for diagnosis, monitoring, prognosis, and identification of cancers for appropriate therapy.
The effects of dietary and nutritional manipulation, and especially of reducing carbohydrate content, on altering our metabolic environment. Carbohydrate restriction in humans mimics many of the metabolic effects of fasting, and may be systematically studied using appropriate in vitro, cell culture, animal models and in vivo biochemical and radiotracer techniques. Of particular interest is the potential for differential systemic metabolic effects on normal compared to malignant/transformed cells.