Nilendu Gupta Ph.D., FAAPM | Nilendu Gupta's Webpage

Vice-Chair, Department of Radiation Oncology,

Professor, Department of Radiation Oncology
Professor, School of Health and Rehabilitation Sciences
Professor, Department of Material Sciences and Engineering
Medical Physics Residency Program Director
Chief of Clinical Medical Physics – Photon Operations

Email: gupta.6@osu.edu
Phone: 614-293-4204
Department of Radiation Oncology,
The Ohio State University, James Cancer Hospital,
460 W 10th Avenue, Columbus, OH 43210

VITA

NILENDU GUPTA

D252L James Cancer Hospital

460 W 10^th Avenue

Columbus, OH 43210.

Ph: (614) 293-4204

Fax: (614) 293-4044

Email: gupta.6@osu.edu

EDUCATION

B.Tech.(Hons), Electrical Engineering (Instrumentation), Indian Institute of Technology, Kharagpur, India, 1987

M.S., Biomedical Engineering (Medical Physics), Ohio State University, Columbus, OH, 1990

Ph.D., Biomedical Eng. (Medical Physics), Ohio State University, Columbus, OH, 1995

EMPLOYMENT

2023-present Vice-Chair of Medical Physics, Department of Radiation Oncology, The Ohio State University, Columbus, OH

2019-present Professor (Clinical), Department of Radiation Oncology, The Ohio State Univ, Columbus, OH

2019-present Professor (Clinical), Department of Health & Rehabilitation Sciences, The Ohio State University, Columbus, OH

2022-present Professor (Clinical), Department of Material Science and Engineering, The Ohio State University, Columbus, OH

2012-2019 Associate Professor (Clinical), Department of Radiation Oncology, Ohio State Univ, Columbus, OH

2013-2019 Associate Professor (Clinical), Department of Health & Rehabilitation Sciences, Ohio State University.

2007-present Chief of Clinical Medical Physics, Department of Radiation Oncology, Ohio State University, Columbus, OH

2003-present Director, Medical Physics Residency Training Program, Department of Radiation Oncology, Ohio State University, Columbus, OH

1998-2012 Assistant Professor, Department of Radiation Oncology, Ohio State Univ, Columbus, OH

1996-present Adjunct Assistant Professor, Nuclear Engineering Program, Ohio State Univ, Columbus, OH

1995-1998 Research Specialist/Medical Physicist, Div. of Radiation Oncology, Dept. of Radiology, Ohio State Univ, Columbus, OH

1988-1995 Graduate Research Associate, Nuclear Engineering Program, Ohio State Univ, Columbus, OH

1987‑1988 Graduate Associate, Nuclear Engineering Program, University of Cincinnati, Cincinnati, Ohio

1987 Engineering Trainee, Tata Iron and Steel Company, Jamshedpur, India.

SCIENTIFIC AND PROFESSIONAL SOCIETIES AND ACTIVITIES

Steering Committee Member, Automated Quality Assurance Consortium (International Multi-Institutional Consortium) (2021- present)
Member of the Board of Directors, Commission on Accreditation of Medical Physics Education Programs. (2021- present)
Council Member, International Council, American Association of Physicists in Medicine, 2021 – present
Chair of Global Data and Information Exchange Committee, American Association of Physicists in Medicine, 2021 – present
Member of Ad Hoc Committee to Evaluate Need for Website Management Systems, American Association of Physicists in Medicine, 2021 – present
Oral Examiner, American Board of Radiology, Therapeutic Radiological Physics (2008 – present)
Accreditation application and Site Reviewer, Medical Physics Residency Programs, Commission on Accreditation of Medical Physics Education Programs. (2017- present)
Member, Asian Oceanic Affairs Subcommittee, American Association of Physicists in Medicine. (2018 – 2020)
Guest Member, Asian Oceanic Affairs Subcommittee, American Association of Physicists in Medicine. (2017)
Surveyor, American College of Radiology, Radiation Oncology Practice Accreditation. (2012 – 2019)
Item-writer, American Board of Radiology, Therapeutic Radiological Physics (2004-2007).
President American Association of Physicists in Medicine, Ohio River Valley Chapter (2004)
President-elect, American Association of Physicists in Medicine, Ohio River Valley Chapter (2003)
Member, Brachytherapy Source Registry Work Group, American Association of Physicists in Medicine. (2007-2009)
Member of Review and Consensus Panel (2000) for The American Brachytherapy Society to develop recommendations for low-dose-rate brachytherapy for carcinoma of the cervix. The American Brachytherapy Society is a professional society with membership open to persons meeting their membership criteria. The review and consensus panels are invited panels among the membership.
Member of Review and Consensus Panel (1999) for The American Brachytherapy Society to develop recommendations for high-dose-rate brachytherapy for carcinoma of the endometrium. The American Brachytherapy Society is a professional society with membership open to persons meeting their membership criteria. The review and consensus panels are invited panels among the membership.

Professional Society Memberships/Certifications:

American Association of Physicists in Medicine: Full Member
American Society for Radiation Oncology: Associate Member
International Society for Neutron Capture Therapy: Member
American Board of Radiology: Diplomate(Therapeutic Radiology)
Certified Radiation Expert – Therapy, State of Ohio
Member of Alpha Nu Sigma, Honor Society of the American Nuclear Society. Membership to Alpha Nu Sigma is an honorary membership, based on academic excellence.

CONSULTATION (INDUSTRY, EDUCATION, GOVERNMENT).

Member, Joint Task Group of American Association of Physicists in Medicine ORV Chapter – Pennsylvania-Ohio Chapter for Ohio Department of Health Rulemaking representation. 2011 to 2014.
Member, American Association of Physicists in Medicine, Brachytherapy Source Registry Work Group, 1/1/2007 to 12/31/2009.
Member the International Commission on Radiation Units and Measurements (ICRU) Heavy Ion Therapy Report, 2006– 2009. ICRU is an international organization that develops and recommends standards for units of radiation and radioactivity, procedures for applying these units in clinical radiology and radiobiology, and the development of standard data for the above applications. Members are elected by the report sponsors and invited to participate in the report based on their expertise in the field.
Member of the International Commission on Radiation Units and Measurements (ICRU) Intensity Modulated Radiation Therapy Report Committee, 2004 – 2010. ICRU is an international organization that develops and recommends standards for units of radiation and radioactivity, procedures for applying these units in clinical radiology and radiobiology, and the development of standard data for the above applications. Consultants are elected by the report committee and invited to participate in the report based on their expertise in the field.
Member the International Commission on Radiation Units and Measurements (ICRU) Electron Report Committee, 2000 – 2003. ICRU is an international organization that develops and recommends standards for units of radiation and radioactivity, procedures for applying these units in clinical radiology and radiobiology, and the development of standard data for the above applications. Members are elected by the report sponsors and invited to participate in the report based on their expertise in the field.

Journal Reviewer for:

Medical Physics

Nuclear Technology

International Journal of Radiation Oncology, Biology and Physics

Journal of Neuro-Oncology

Ohio Cancer Research Associates

Fourteenth International Conference on the Applications of Accelerators In Research and Industry

PATENTS DISCLOSED

Woods, K., Ayan, A., Woollard, J, Gupta, N., 2017. A SIX DEGREES-OF-FREEDOM QUALITY ASSURANCE PHANTOM FOR RADIATION THERAPY LINEAR ACCELERATORS. U.S. Patent 10,932,748 issued on 3/2/2021.

PATENTS UNDER REVIEW/PROVISIONAL PATENTS

P2024-090-8521 PORTAL LIQUID HELIUM-FREE MRI-GUIDED PROTON THERAPY SYSTEM

P2024-048-8261 SYSTEM AND METHODS FOR DOSE AND DOSE RATE CONTROL IN ELECTRON FLASH PLATFORMS

P2023-213-7874- Beam-Modifying Device for Ultra-High Dose Rate Medical Electron Linear Accelerators

P2023-121-7698 – Collimators for ultra-high dose rate radiation generating device

P2022-348-7360—METHODS AND SYSTEMS FOR MEASURING AND CONTROLLING RADIOSURGERY SYSTEMS

P2022-230-7225— CONTINUITY AND DISASTER RECOVERY SOLUTION FOR PATIENTS UNDER TREATMENT IN RADIATION ONCOLOGY

T2021-297 White, J., and Gupta, N., – Prone positioning board for delivery of radiation therapy to breast radiation therapy. (IDF-052876)

ADMINISTRATIVE SERVICE

a) Administrative positions held

Vice-Chair of Medical Physics, Department of Radiation Oncology, Ohio State University Medical Center, 2023 – present.
Co-Chair Department of Radiation Oncology Promotion and Tenure Committee – 2023-present
Chief of Clinical Medical Physics, Department of Radiation Oncology, Ohio State University Medical Center, 2007 – present.
Director, Medical Physics Residency Training Program, 2003 – present
Co-Chair, Department of Radiation Oncology Promotion & Tenure Committee, 2022-present

b) Departmental Committees

Co-Chair Department of Radiation Oncology Promotion and Tenure Committee – 2023-present

Medical Physics Residency Program Committee – Chair (2003 – present)

Medical Physics Residency Admissions Subcommittee – Chair (2003 – present)

Medical Physics Residency Curriculum Subcommittee – Chair (2003 – present)

Radiation Oncology Education Committee (2005 – present)

Radiation Oncology Clinical Operations Committee (2005 – present)

Radiation Oncology Strategic Planning Committee (2005 – 2012)

Radiation Oncology Promotion and Tenure Committee (2005 – present)

Radiation Therapy Program Advisory committee (2001 – present)

Category M Graduate Faculty in Nuclear Engineering Program, Dept. of Mechanical Engineering, 1996-present

Nuclear Engineering Graduate Program Committee, 1996-present

c) Medical Center/ College of Medicine/University Committees

Member – The Ohio State University, College of Medicine, Promotion and Tenure Committee, 2020 – present

Member – The Ohio State University, Wexner Medical Center, Radiation Advisory Group, 2016 – present.

Member – The Ohio State University, X-Ray Safety Oversight Committee, 2012 – present

Member – Medical Center Radiation Safety & QA Committee, 2006 – present

Member – The Ohio State University Radiation Safety Oversight Committee, 2006- present

Member – The Ohio State University Radiation Safety Medical Use subcommittee, 2006 – present

Member – OSU Nuclear Reactor Operations Oversight Committee, 1998 – present. Nuclear Reactor Operations Committee is the oversight committee that reports to the University Provost for safe use of the OSU Nuclear Research Reactor and charged to review and to audit reactor operations to assure the facility is operated in a manner consistent with public safety and within the terms of the facility license.

Chair – The Ohio State University Radiation Safety Oversight Committee, 2011-2012

Chair – The Ohio State University Radiation Safety Audit sub-committee, 2010-2011

Vice Chair – The Ohio State University Radiation Safety Oversight Committee, 2010-2011

Member – OSU College of Medicine Faculty Council, 2006 – 2008.

Member – OSU Medical Center Clinical Technology and Product Assessment Committee, 2006 – 2008.

Steering Committee – Project Proton-Particle Therapy, July 2004 – 2007. The Steering committee was appointed by Dean Sanfilippo to oversee Particle Therapy efforts at the University, with a charge to define the vision, program priorities, site/design, and phasing; oversee and direct activities of the Working Group; and recommend a final strategic plan to the Dean, the President, and the Board of Trustees.

Working Group – Project Proton-Particle Therapy, July 2004 – 2007. The Working Group was appointed by Dean Sanfilippo to deliver a workable business plan to the Steering Committee for Particle Therapy efforts at the University.

d) Affirmative action and mentoring activities

Not Applicable

HONORS AND AWARDS

2019 Volunteer Service Award, American Board of Radiology.

Fellow, American Association of Physicists in Medicine, inducted July 2018

Ohio State Univ.: 2006 Excellence in Teaching Award, College of Medicine.

Univ. of Cincinnati: Alpha Nu Sigma, Honor Society of the American Nuclear Society.

Ohio State Univ.: 1993 Nuclear Engineering Achievement Award for Excellence in Research.

CURRENT RESEARCH INTERESTS

My current research interests are in the optimization of chemo radiation strategies, development of radiation measurement systems in biology and medicine, development of clinical treatment planning methods and development of clinical trials in the department.

Over the past few years my clinical research interests are in developing and standardizing QA processes and programs. Our department currently has ten truebeam accelerators, which we planned and executed the commission for as dosimetrically equivalent and beam matched machines. My group has developed QA data repositories that allow us to compare and dashboard data from all our linacs and detect trends and variations between machines. Recently, I have been part of a core team that designed and is implementing a quality, operations and outcomes database repository within the department.

I have an interdisciplinary background with a Masters and PhD in Biomedical Engineering, and I am a category M faculty in the Nuclear Engineering Graduate program, and on the Medical Applications track. I currently advise graduate students in Nuclear Engineering for their masters projects as needed and a part of the Medical Applications research group in Nuclear Engineering, and medical students and medical and medical physics residents in various dosimetry projects.

In the past I have been involved with research in Boron Neutron Capture Therapy (BNCT) physics, mixed field dosimetry. I have extensively used neutron/photon/ electron Monte Carlo Transport codes to model the moderator (filter) assembly for the accelerator-based epithermal neutron source for BNCT and come up with a suitable design for fabrication and to predict the dosimetry in head phantoms. I have fabricated the first complete moderator assembly prototype, which is still used in the neutron beam research here at OSU. I also conduct research in modeling the different dose components in a mixed radiation field and used them to develop a rudimentary treatment planning system for BNCT with an algorithm to analyze brain tolerance from the mixed radiation field. This tool has been used extensively in our research for designing better neutron beams for better performance for deep-seated tumors, and participated in designing and conducting clinical trials around drug delivery and resulting dosimetry.

The above research interests have evolved into evaluation and design of combination therapies that involve radiation therapy. I have subsequently been involved with several collaborators in conducting small animal studies to evaluate combination therapies and optimizing drug and radiation delivery times.

My other clinical research interests are in state of the art radiotherapy delivery methods and objective ways of creating an image and knowledge-guided target for Radiosurgery, 3D Treatment Planning, Conformal Radiation Therapy, and Intensity Modulated Radiation Therapy. We have developed a Nodal Atlas as a tool for target definition in Radiation Oncology. This nodal atlas would aid the radiation oncologist in objectively determining the clinical target volume based on the gross target volume and clinical information like staging. We have produced an interactive CD-based 2D Nodal Atlas utilizing Adobe Acrobat, which will be computer platform-independent. However, a key use of the cross-sectional nodal atlas would be to have it available as a reconstructed 3D atlas. Visualization of nodal stations in 3D, as well as their relationships with surrounding normal tissues, will help the radiation oncologist to determine the optimal beam design in a BEV (Beams Eye-View) environment. Various levels of intelligence can then be built in to this atlas, like tumor staging and nodal involvement probabilities to expand this tool. This would provide a combined tool for the radiation oncologist to weight the complication risk vs. benefit of tumor control in planning complex treatments such as conformal and intensity modulated radiotherapy.

I have actively participated in collaborating with several clinical faculty in designing and developing clinical trials for radiation treatments in institutional trials, and helped open many national clinical trials by completion of the credentialing and a data submission infrastructure in the department.

CLINICAL EXPERIENCE/ INTERESTS

I have more than twenty years of experience in clinical medical physics, and have commissioned more than fifteen linear accelerators, multiple treatment planning systems and other radiotherapy equipment. I have introduced every modern radiotherapy technique in the clinic. In my leadership role as a chief of clinical medical physics I have been involved with strategic planning for departmental programs, recruitment, and design, construction, equipment installation planning and clinical go live for three new cancer center buildings, including our Proton Therapy center, and an outreach cancer center. I have also led the development and expansion of our department IT infrastructure to enable the rapid expansion and support of the Radiation Oncology Department, including the strong portfolio of innovative software tools to enhance operations, like multiple whiteboards for management of clinical workflows and numerous automated scripts for automation of quality and safety operations. I have recruited over 30 highly talented faculty and staff physicists into the James Cancer Hospital to build a strong medical physics program to support our academic, clinical, and teaching mission areas.

PUBLICATIONS

PAPERS PUBLISHED IN ARCHIVAL JOURNALS:

Lu L, Yang X, Raterman B, Jiang X, Meineke M, Grecula J, et al. Assessment of MRI image distortion based on 6 consecutive years of annual QAs and measurements on 14 MRI scanners used for radiation therapy. J Appl Clin Med Phys. 2023;24(1):e13843. doi: 1002/acm2.13843

Jain S, Cetnar A, Woollard J, Gupta N, Blakaj D, Chakravarti A, et al. Pulse parameter optimizer: an efficient tool for achieving prescribed dose and dose rate with electron FLASH platforms. Physics in medicine and biology. 2023;68(19). https://doi.org/10.1088/1361-6560/acf63e

Cuitiño,MC., Fleming, JL., Jain, S., Cetnar, A., Ayan, AS., Woollard, J., Manring, H., Meng, W., McElroy, JP., Blakaj, DM., Gupta, N., Chakravarti, A., “Comparison of Gonadal Toxicity of Single-Fraction Ultra-High Dose Rate and Conventional Radiation in Mice”, Advances in Radiation Oncology, Volume 8, Issue 4, 2023, 101201, ISSN 2452-1094, https://doi.org/10.1016/j.adro.2023.101201

Sumption M, Benali A, Lu L, Gupta N, Collings E. “Monte Carlo Simulations of the Effect of Magnetic field on Deposited dose in Proton Therapy”. Bulletin of the American Physical Society, 2023.

Collings EW, Lu L, Gupta N, Sumption MD, “Accelerators, Gantries, Magnets and Imaging Systems for Particle Beam Therapy: Recent Status and Prospects for Improvement,” Frontiers in Oncology 2022 Vol. 11, DOI=10.3389/fonc.2021.737837, 2022.

Ayan AS., Kim, G., Whitaker. M., Al-Hallaq, H., Hsu. SH., Woollard J., Roberts DA., Shtraus N., Gao S., Gupta N., and Moran JM., “A framework for automated and streamlined kV cone beam computed tomography image quality assurance: a multi-institutional study,” Biomedical Physics & Engineering Express, Volume 7, Number 6 (2021). http://dx.doi.org/10.1088/2057-1976/ac2876

Cetnar, A., Ayan, A., Graeper, G., Weldon, M., Woods, K., Klamer, B., Pan, P., Martin, D., Diaz D.A., Gupta, N., “Prospective dual-surrogate validation study of periodic imaging during treatment for accurately monitoring intrafraction motion of prostate cancer patients.” Radiotherapy and oncology 157: 40-46, (2021). https://doi.org/10.1016/j.radonc.2021.01.020

Halvorsen P, Gupta N, Rong Y. Clinical practice workflow in Radiation Oncology should be highly standardized. J Appl Clin Med Phys. 20(4):6-9. doi: 10.1002/acm2.12555. Epub 2019 Mar 12. PubMed PMID: 30861297; PubMed Central PMCID: PMC6448160.

Grzetic, S.; Ayan, A.S.; Woollard, J.; Gupta, N.; (2018). Validating kQ =1.0 assumption in TG51 with PTW 30013 farmer chamber for Varian TrueBeam’s 2.5 MV imaging beam. J Appl Clin Med Phys, 19: 351-354. doi:10.1002/acm2.12290

Woods, K.; Ayan, A.S.; Woollard, J.; Gupta, N. (2017). Quality assurance for a six degrees-of-freedom table using a 3D printed phantom. Journal of Applied Clinical Medical Physics, 19: 115-124. doi:10.1002/acm2.12227

Bazan, J., D. DiCostanzo, K. Kuhn, L. Majithia, A. Quick, N. Gupta and J. White. “The Likelihood of Unacceptable Normal Tissue Doses in Breast Cancer Patients Undergoing Regional Nodal Irradiation in Routine Clinical Practice.” Pract Radiat Oncol 7(3): 154-160, (2017).
http://dx.doi.org/10.1016/j.prro.2016.10.012

Majithia, L., Rong, Y., Siddiqui, F., Hattie, T., Gupta, N., Weldon, M., Chakravarti, A., Wong, H. K., Porcu, P., Xu-Welliver, “M. Treating Cutaneous T-Cell Lymphoma with Highly Irregular Surfaces with Photon Irradiation Using Rice as Tissue Compensator”, Frontiers in Oncology, 5, 49. (2015). http://doi.org/10.3389/fonc.2015.00049

Lu L, Filippi J, Patel A, Gupta N, Weldon M, Woollard J, Ayan A, Rong Y, Martin D, Pelloski C, Welliver MX, “A Clinical Dosimetry Analysis of Total Body Irradiation for Leukemia Patients”, International Journal of Medical Physics, Clinical Engineering and Radiation Oncology (IJMPCERO), Vol. 3, 31-42, 2014. http://dx.doi.org/10.4236/ijmpcero.2014.31006

Chaswal V, Weldon M, Gupta N, Chakravarti A, Rong Y, “Commissioning and Comprehensive Evaluation of the ArcCHECK Cylindrical Diode Array for VMAT Pre-treatment Delivery QA”, J Appl Clin Med Phys, June, 2014; 15(4):212-225. doi: 10.1120/jacmp.v15i4.4832.

Lu, L., Yembi-Goma, G., Wang JZ., Gupta, N., Huang, Z., Lo, SS., Martin, D., Mayr, N., “Practical Method to Evaluate and Verify Dose Calculation Algorithms in the Treatment Planning System of Radiation Therapy”, International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, Vol. 2 No. 3, 2013, pp. 76-87. doi: 10.4236/ijmpcero.2013.23011.

McGregor, J., Grecula, J., Ammirati, M., Pelloski, C., Lu, L., Gupta, N., Bell, S., “LONG TERM FOLLOW-UP AFTER STEREOTACTIC RADIOSURGERY FOR THE TREATMENT OF MENINGIOMAS”, NEURO-ONCOLOGY 15, 184-184, 2013

Lu, L., Bondra, K., Gupta, N., Sommerfeld, J., Chronowski, C., Leasure, J., Singh, M., Pelloski, C., “NanoDots Dosimetry for RS 2000 X-Ray Biological Irradiator”, International Journal of Radiation Biology, accepted on June 12, 2013. doi:10.3109/09553002.2013.817703

Racke FK, Baird M, Barth RF, Huo T, Yang W, Gupta N., Weldon M., Rutledge H., “Unique In Vitro and In Vivo Thrombopoietic Activities of Ingenol 3,20 Dibenzoate, A Ca++- Independent Protein Kinase C Isoform Agonist.” PLoS ONE 7(12): e51059. doi:10.1371/journal.pone.0051059, (2012)

Barth RF, Yang W, Huo T, Riley KJ, Binns PJ, Grecula JC, Gupta N, Rousseau J, Elleaume H., “Comparison of intracerebral delivery of carboplatin and photon irradiation with an optimized regimen for boron neutron capture therapy of the F98 rat glioma.” Appl Radiat Isot. 2011 Mar 21. PMID: 21493080

Yang W, Huo T, Barth RF, Gupta N, Weldon M, Grecula JC, Ross BD, Hoff BA, Chou TC, Rousseau J, Elleaume H. Convection enhanced delivery of carboplatin in combination with radiotherapy for the treatment of brain tumors. J Neurooncol. 2011 Feb;101(3):379-90. Epub 2010 Jun 25. Erratum in: J Neurooncol. 2011 Feb;101(3):391. PubMed PMID: 20577779

Lo SS, Clarke JW, Grecula JC, McGregor JM, Mayr NA, Cavaliere R, Kendra KL, Gupta N, Wang JZ, Sar-kar A, Olencki TE. Stereotactic radiosurgery alone for patients with 1-4 radioresistant brain metastases. Med Oncol. 2010 Sep 3. [Epub ahead of print] PubMed PMID: 20814764

Clarke J W, Register, S., McGregor, J., Grecula, J. C., M.D., Mayr, N. A., Wang, J.Z., Li, K., Gupta, N., Kendra, K.L., Olencki, T., Cavaliere, R., Sarkar, A., Lo, S.S., “Stereotactic Radiosurgery With or Without Whole Brain Radiotherapy for Patients with a Single Radioresistant Brain Metastasis.” American Journal Of Clinical Oncology [Am J Clin Oncol], ISSN: 1537-453X, 2010 Feb; Vol. 33 (1), pp. 70-4; PMID: 19652578

Huang Z, Mayr NA, Yuh WT, Lo SS, Montebello JF, Grecula JC, Lu L, Li K, Zhang H, Gupta N, Wang JZ,. “Predicting outcomes in cervical cancer: a kinetic model of tumor regression during radiation therapy,” Cancer Research [Cancer Res], ISSN: 1538-7445, 2010 Jan 15; Vol. 70 (2), pp. 463-70; PMID: 20068180.

Yuan J, Wang JZ, Lo S, Grecula JC, Ammirati M, Montebello JF, Zhang H, Gupta N, Yuh WTC, Mayr NA. Hypofractionation regimens for stereotactic radiotherapy of large brain tumors. Int J Radiat Oncol Biol Phys 2008; 72: 390-397.

Nag S, Shi P, Liu B, Gupta N, Bahnson RR, Wang JZ. “Comparison of real-time intraoperative ultrasound-based dosimetry with postoperative computed tomography-based dosimetry for prostate brachytherapy”. Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):311-7

Zhang H, Wang JZ, Mayr N, Kong X, Yuan J, Gupta N, Lo S, Grecula J, Montebello J, Martin D, Yuh W. “Fractionated grid therapy in treating cervical cancers: conventional fractionation or hypofractionation”, Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):280-8

Gao M; Wang JZ; Nag S; Gupta N; “Effects of seed migration on post-implant dosimetry of prostate brachytherapy.” Med Phys 2007 Feb; Vol. 34 (2), pp. 471-80.

Bratasz A, Pandian RP, Deng Y, Petryakov S, Grecula JC, Gupta N, Kuppusamy P. “In vivo imaging of changes in tumor oxygenation during growth and after treatment.” Magn Reson Med. 2007 May;57(5):950-9.

Wang, J.Z., Mayr, N., Nag, S., Montebello, J., Gupta, N., Samsami, N., and Kanellitsas, C., “Effect of edema, relative biological effectiveness, and dose heterogeneity on prostate brachytherapy,” Medical Physics, 33(4), pp. 1025-1032, 2006.

Koc, M., McGregor, J., Bauer, C., Gupta, N., Gahbauer, R. “Gamma Knife radiosurgery for intracranial metastatic melanoma: an analysis of survival and prognostic factors”, Journal of Neuro-Oncology 71 , 307-313 2005.

Gahbauer , R., Landberg , T., Chavaudra, J., Dobbs, J., Gupta, N., Hanks, G., Horiot, J.-C., K.-A. Johansson, Möller, , Naudy, S., Purdy, J., Santenac, I., Suntharalingam, N., Svensson, H., DeLuca, P. M., Wambersie, A., Whitmore, G., Akanuma, A., Brahme, A., De Nerve, W., Georg, D., Grégoire, V., Pötter , R.,“Prescribing, Recording, and Reporting Electron Beam Therapy,” Journal of the ICRU 4: 2 (ICRU Report 71), 2004.

Barth, R. F., Grecula, J. C., Yang, W., Rotaru, J. H., Nawrocky, M., Gupta, N., Albertson, B. J., Ferketich, A. K., Moeschberger, M. L., Coderre, J. A., and Rofstad, E. K., “Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors,” International Journal of Radiation Oncology*Biology*Physics 58, 267-277, 2004.

Gupta, N., Gahbauer, R. A., Blue, T. E., and Albertson, B., “Common Challenges and Problems in Clinical Trials of Boron Neutron Capture Therapy of Brain Tumors,” Journal of Neuro-Oncology 62 , 197-210, 2003.

Roychowdhury S, Peng R, Baiocchi R, Bhatt D, Vourganti S, Grecula J, Gupta, N., Eisenbeis, C.F., Nuovo, G.J., Yang W., Schmalbrock, P., Ferketich, A., Moeschberger, M., Porcu, P., Barth, R.F., Caligiuri, M., “Experimental Treatment of Epstein-Barr Virus-associated Primary Central Nervous System Lymphoma,” Cancer Research 63, 965-971, 2003.

Manolitsas, T. P., Fowler, J. M., Gahbauer, R. A., and Gupta, N., “Pain in the foot: calcaneal metastasis as the presenting feature of endometrial cancer,” Obstetrics and gynecology 100, 1067-1069, 2002.

Nag, S., Chao, C., Erickson, B., Fowler, J., Gupta, N., Martinez, A., Thomadsen, B., for The American Brachytherapy Society, “The American Brachytherapy Society recommendations for low-dose-rate brachytherapy for carcinoma of the cervix,” Int. J. Radiation Oncology Biol. Phys., 52(1): 33-48, (2002).

Woollard, J.E., Blue, T.E., Gupta, N., Gahbauer, R.A., “Development and Calculation of an Energy Dependent Normal Brain Tissue Neutron RBE for Evaluating Neutron Fields for BNCT,”, Health Physics, 80: 583-589(2001).

Evans, J.F., Blue, T.E., Gupta, N., “Absorbed dose estimates to structures of the brain and head using a high-resolution voxel-based head phantom,” Medical Physics 28:780-786 (2001).

Woollard, J.E., Albertson, B. J., Reed, M. K., Blue, T.E., Capala, J., Gupta, N., Gahbauer, R.A. “A Comparison of Neutron Beams for BNCT Based on In-Phantom Neutron Field Assessment Parameters” , Medical Physics, 28(2): 184-193, (2001).

Goodman, J.H., Yang, W., Barth, R.F., Gao, Z., Boesel, C.P., Staubus, A.E., Gupta, N., Gahbauer, R.A., Adams, D.M., Gibson, C.R., Ferketich, A.K., Moeshberger, M.L., Carpenter, D.E., Bauer, W.F., Zhang, M., Wang, C.C., “Boron Neutron Capture Therapy of brain tumors: Biodistribution, pharmacokinetics and radiation dosimetry of sodium borocaptate in patients with glioma,” Neurosurgery, 47(3):608-622, (2000).

Nag, S., Erickson, B., Parikh, S., Gupta, N., Varia, M., Glasgow, G., “The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the endometrium,” International Journal of Radiation Oncology, Biology, Physics, 48(3):779-790, (2000).

Nag S, Gupta N. Dose equivalence for HDR prostate brachytherapy: In response to Drs. Jones and Madsen. Letter to Editor. Int J Radiat Oncol Biol Phys. 48:907-908, (2000).

S., Gupta N., “A simple method of obtaining equivalent doses for use in HDR brachytherapy,” International Journal of Radiation Oncology, Biology, Physics, 46(2):507-513, (2000).

Nag S., Gupta N., Martinez-Monge R., “Brachytherapy for the interventional cardiologist and vascular surgeon,” Cardiovascular Radiation Medicine 1(2):160-168, (1999).

Martinez-Monge, R., Fernandes, P.S., Gupta, N., Gahbauer, R., “Cross-sectional Nodal Atlas: A Tool for the Definition of Clinical Target Volumes in Three-dimensional Radiation Therapy Planning,” Radiology, 211(3):815-828, (1999).

Barth, R.F., Soloway, A.H., Goodman, J.H., Gahbauer, R.A., Gupta, N., Blue, T.E., Yang, W., Tjarks, W., “Boron Neutron Capture Therapy of Brain Tumors: An Emerging Therapeutic Modality,” Neurosurgery 44: 433-451 (1999)

Gahbauer, R., Gupta, N., Blue, T., Goodman, J., Barth, R., Grecula, J., Soloway, A.H., Sauerwein, W., Wambersie, A., “Boron neutron capture therapy: principles and potential,” Recent Results in Cancer Research, 150: 183-209 (1998)

Nag, S., Martinez-Monge, R., Zhang, H., Gupta, N., “Simplified non-looping functional loop technique for HDR brachytherapy,” Radiotherapy and Oncology, 48(3):339-41 (1998)

Woollard, J.E., Blue, T.E., Gupta, N., Gahbauer, R.A. “Evaluation of moderator assemblies for use in an accelerator-based neutron source for boron neutron capture therapy,” Nuclear Technology, 123(3):320-334, (1998).

Nag, S., Martinez-Monge, R., Gupta, N., “Intraoperative radiation therapy using electron-beam and high-dose-rate brachytherapy,” The Cancer Journal, 10(2):94-101 (1997).

Gahbauer, R., Gupta, N., Blue, T. E., Goodman, J., Grecula, J., Soloway, A. H., Wambersie, A., “BNCT: Status and dosimetry requirements,” Radiation Protection Dosimetry, 70(1-4):547-554 (1997)

Wollard, J. E., Blue, T. E., Gupta, N., Gahbauer, R. A., “Development and Application of Neutron Field Optimization Parameters for an Accelerator Neutron Source for Boron Neutron Capture Therapy,” Nucl. Tech., 115(1):100-113, (1996).
Blue, T. E., Wollard, J. E., Gupta, N., Greskovich J. F. Jr., “An Expression for the RBE of Neutrons as a Function of Neutron Energy” Phys. Med. Biol., 40:757-767 (1995).

Gupta, N., Gahbauer, R. A., Blue, T. E., Wambersie, A., “Dose Prescription in Boron Neutron Capture Therapy,” Int. J. Radiat. Oncol. Biol. Phys., 28(5) : 1157-1166 (1994).

T. E., Gupta, N., Wollard, J. E., “A Calculation of the Energy Dependence of the RBE of Neutrons,” Phys. Med. Biol., 38: 1693-1712 (1993).

Gupta, N., Niemkiewicz, J., Blue, T., Gahbauer, R. A., Qu, T. X. “Effect of head phantom size on 10B and 1H[n,g]2H dose distributions for a broad field accelerator neutron source for BNCT,” Med. Phys. 20 (2 pt. 1): 395-404 (1993).

ABSTRACTS PUBLISHED IN ARCHIVAL JOURNALS:

Lu L, Yang X, Raterman B, Jiang X, Meineke M, Grecula J, Blakaj D, Palmer J, Raval R, Thomas, E, Hintenlang D, Gupta, N. “Assessment of MRI image distortion based on 6 consecutive years of annual QAs and measurements on 14 MRI scanners used for radiation therapy”, J Appl Clin Med Phys. 2023;24(1):e13843.
Ben Ali* A, Majoros M, Zhang X, Collings E, Gupta N, Sumption M, Lu L, Monte-Carlo Study of Dose Contribution From Secondary Particles in MRI-Guided Proton Therapy, EPoster presentation, 2022 Annual AAPM Conference, Washington DC

Jain* S, Woollard J, Cetnar A, Gupta N, Ayan A, Validation of a Novel Device for Characterizing Ultra High Dose Rate (FLASH) Electron Beams, Oral presentation, 2022 Annual AAPM Conference, Washington DC

Steers* J, DeMarco J, Al-Hallaq H, Mikell J, Barnes M, Kim5 G, Gupta N, DiCostanzo D, Ayan A, Perez M, Irrer J, Moran J, Utility of EPID-Based Automated Quality Assurance (AQA) Test Suite for Verifying Machine Performance Following Non-Routine Maintenance Events, Oral presentation, 2022 Annual AAPM Conference, Washington DC

Cetnar* A, DiCostanzo D, Weldon M, Mathews J, Swanson J, Gupta N, Blinding of Residency Applications in Medical Physics – Promises and Pitfalls, Best of Professional presentation, 2022 Annual AAPM Conference, Washington DC

Lu, L., Majoros, M., Collings, EW., Gupta N., Sumption, MD, “Potential Applications of MTS and HTS to MRI Imaging Systems for Particle Beam Therapy”, International Journal of Radiation Oncology*Biology*Physics, Volume 111, Issue 3, Supplement, Pages S46-S47, 2021,

Lu, L.,Yang, X., Raterman, B., Jiang, X., Meineke, M., Hintenlang, D., Gupta, N., “Report of Image Distortion Based On Five Consecutive Years of Annual QA On Six MRI Scanners Used for Radiation Therapy”, ePoster at 2021 ASTRO Annual Meeting

Ayan, A., Blakaj, D., Chakravarti, A., Gupta, N., Woollard, J., “Development of a Software Tool for FLASH Dose and Dose Rate Optimization for IntraOp Mobetron”, Accepted for ePoster presentation at the 2021 AAPM Annual meeting, (2021).

Swanson A, DiCostanzo D, Gupta N, Hintenlang K, Cetnar A. Failure Modes and Effects Analysis of Low Dose Bilateral Whole Lung Irradiation Treatment for COVID-19 Positive Patients Requiring Respiratory Ventilation. Interactive ePoster at 2021 AAPM Virtual Annual Meeting

Steinmann, A., Jain, S., Ayan, A., Gupta, N., Woollard, J., “Validating Radiance’s Treatment Planning System for Image‐Guided Intra‐Operative Radiation Therapy Using Plastic Cones” BReP‐SNAP‐M‐149, (2020), Scientific Abstracts and Sessions. Med. Phys., 47: e255-e880. doi:10.1002/mp.14316

Jain, S., Steinmann, A., Woollard, J., Gupta, N., Ayan, A, “Dosimetric Comparison of CT Compatible Plastic Cones to Traditional Metal Cones for IntraOp Radiation Therapy” PO‐GeP‐M‐171, (2020), Scientific Abstracts and Sessions. Med. Phys., 47: e255-e880. doi:10.1002/mp.14316

Cetnar, A., Ayan, A., Graeper, G., Weldon, M., Woods, K., Gupta, N., “Validation of Intrafraction Motion Review Using Dual Surrogate in Prospective Clinical Study” PO‐GeP‐M‐426, (2020), Scientific Abstracts and Sessions. Med. Phys., 47: e255-e880. doi:10.1002/mp.14316

Gupta, N., DiCostanzo, D., Ayan, A., Woollard, J., Meissner, J., Hintenlang, K., “A Parametric Approach Towards New Proton Facility Shielding Considerations in the Era of Proton FLASH Therapy”, PO‐GeP‐T‐55, (2020), Scientific Abstracts and Sessions. Med. Phys., 47: e255-e880. doi:10.1002/mp.14316

Morelli, S., Woollard, J., Ayan, A., Gupta, N., “CivaSheet Commissioning and Workflow Planning”, PO‐GeP‐T‐183, (2020), Scientific Abstracts and Sessions. Med. Phys., 47: e255-e880. doi:10.1002/mp.14316

Martin, M, Hintenlang, K, Gupta, N, Meissner, J, Smathers, J, (2019) Will Your Facility Shielding Be Adequate for New Proton Treatment Techniques? MEDICAL PHYSICS 46 (6), E550-E550

Gee, V, Cetnar, A, Gupta, N, (2019) Evaluation of Materials for a Pediatric On-Treatment Video Projection System MEDICAL PHYSICS 46 (6), E582-E582

Christ, D, Ayan, A, Weldon, M, Gupta, N (2019) Intra-Fraction Motion Tracking of Head and Neck Patients Using Surface Image Guidance, MEDICAL PHYSICS 46 (6), E164-E165

Mamounas, E P, Bandos, H, White, JR, Julian, TB, Khan, AJ, Shaitelman, SF, Torres, MA, Vicini, F, Ganz, PA, McCloskey, SA, Paik, S, Gupta, N, Li, XA, DiCostanzo, DJ, Curran WJ, Jr., and Wolmark, N, NRG Oncology/NSABP B-51/RTOG 1304: Phase III trial to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to whole breast RT post breast-conserving surgery (BCS) reduces invasive breast cancer recurrence-free interval (IBCR-FI) in patients (pts) with pathologically positive axillary (PPAx) nodes who are ypN0 after neoadjuvant chemotherapy (NC)., Journal of Clinical Oncology 2019 37:15_suppl, TPS600-TPS600

Bazan, JG, Stephens, J, Agnese, D, Skoracki, R, Arneson, K, Reiland, J, Gupta, G, Gallagher, K, McElroy, S, Gupta, N, White, JR, Abstract OT2-04-04: Multi-institution phase II trial of intraoperative electron beam radiotherapy boost at the time of breast conserving surgery with oncoplastic reconstruction in women with early-stage breast cancer, Cancer Research 79 (4 Supplement), OT2-04-04-OT2-04-04

Welliver, M. X., Vasu, S., Weldon, M., Zoller, W., Addington, M., Eiler, D., Jacob, N.K., Denko, N., Martin, D., Gupta, N., Liu, A., Rong, Y., Wong J.Y.C., White, J.R., White, J.; “Utilizing Organ-Sparing Marrow-Targeted Irradiation (OSMI) to Condition Patients with High-risk Hematologic Malignancies Prior to Allogeneic Hematopoietic Stem Cell Transplantation: Results from a Prospective Pilot Study.” INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 102(3): E370-E371. (2018).

Li, Y., DiCostanzo, D., Gupta, N., & Ayan, A. (2018). Evaluation of the Clinical Planning Target Volume (PTV) Expansion Margin and Imaging Frequency in the Treatment of Head and Neck (HN) Cancer. Medical Physics, 45(6), E190-E190.

Christ, D., Noa, K., Carlson, M., & Gupta, N. (2018). How Normalization Method Affects Target Coverage for Leipzig-Style Applicators in UDR Skin Brachytherapy. Medical Physics, 45(6), E173-E173.

Carlson, M., Gupta, N., Noa, K., & Christ, D. (2018). Comparison of Vertical and Horizontal Oriented Source Leipzig-Style Skin Brachytherapy Applicators. Medical Physics, 45(6), E242-E242.

DiCostanzo, D., Fullenkamp, M., Klipfer, J., Danker, J., Cetnar, A., Gupta, N., & Hintenlang, K. (2018). Mentoring Model for Allied Health Professionals and Clinical Staff. Medical Physics, 45(6), E201-E201.

Gupta, N., Ayan, A., DiCostanzo, D., Carlson, M., & Woollard, J. (2018). Development of a Robust Linac QA Program for Multiple Beans Matched and Dosimetrically Equivalent TrueBeams. Medical Physics, 45(6), E610-E610.

Meineke, M., DiCostanzo, D., Ayan, A., Woollard, J., Hintenlang, K., & Gupta, N. (2018). Integrated Delivery of Outreach Physics Services. Medical Physics, 45(6), E207-E207.

Weldon, M., Khamsi, Y., & Gupta, N. (2018). Comparison of Radiological Properties of Materials Used in Radiation Therapy. Medical Physics, 45(6), E253-E253.

Nealon, K., Ayan, A., Gupta, N., & Woollard, J. (2018). Development and Application of a High Precision Optical Guidance System for Customizable I-125 Eye Plaque Production. Medical Physics, 45(6), E524-E525.

Gupta, N., Ayan, A., DiCostanzo, D., Carlson, M., & Woollard, J. (2018). Development of a Robust Linac QA Program for Multiple Beans Matched and Dosimetrically Equivalent TrueBeams. Medical Physics, 45(6), E610-E610.

Bazan, JG; Stephens, J; Terando, A; Skoracki, R; McElroy, S; Sexton, J; Gupta, N; White, J. (2018). Abstract OT2-03-01: Multi-institution phase II trial of intraoperative electron beam radiotherapy boost at the time of breast conserving surgery with oncoplastic reconstruction in women with early-Stage breast cancer. Cancer Research. 78(4). OT2-03. 10.1158/1538-7445.SABCS17-OT2-03-01.

White, J; McElroy, S; Sekhon, A; Wei, L; Bazan, J; Yang, X; Dicostanzo, D; Kuhn, K; Gupta, N; Knopp, M. (2018). Abstract OT2-03-04: Feasibility of assessing radiation response with MRI/CT directed preoperative accelerated partial breast irradiation in the prone position for hormone responsive early stage breast cancer. Cancer Research. 78. OT2-03. 10.1158/1538-7445.SABCS17-OT2-03-04.

Mamounas, EP; Bandos, H; White, JR; Julian, TB; Khan, AJ; Shaitelman, SF; Torres, MA; Vicini, FA; Ganz, PA; McCloskey, SA; Paik, S; Gupta, N; Li, XA; DiCostanzo, DJ; Costantino, JP; Curran Jr, WJ; Wolmark, N; (2018). Abstract OT2-03-02: NRG oncology/NSABP B-51/RTOG 1304: Phase III trial to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to breast RT post breast-conserving surgery (BCS) reduces invasive breast cancer recurrence-free interval (IBCR-FI) in patients (pts) with positive axillary (PAx) nodes who are ypN0 after neoadjuvant chemotherapy (NC). Cancer Research. 78(4). OT2-03. 10.1158/1538-7445.SABCS17-OT2-03-02.

White, J., McElroy, S., Seykon, A., Wei, L., Bazan, J., Yang, X., DiCostanzo, D., Gupta, N., Knopp, M. (2017). Feasibility of assessing radiation response with MRI/CT directed preoperative accelerated partial breast irradiation in the prone position for hormone sensitive early stage breast cancer. Cancer Research, 77. doi:10.1158/1538-7445.Sabcs16-Ot2-03-02

Woollard, J., Ayan, A., DiCostanzo, D., Carlson, M., & Gupta, N. (2017). A Review of TG-142 QA Results for Nine Dosimetrically Equivalent True Beams Over Two Years of Operation. Medical Physics, 44(6), 3227-3227.

Taylor, W., Carlson, M., Quick, A., & Gupta, N. (2017). Characterizing Needle Applicator Displacement for Gynecological High-Dose-Rate Interstitial Treatment. Medical Physics, 44(6).

Taylor, W., Ayan, A., Woollard, L., & Gupta, N. (2017). A Computer Program for Physics Second Manual Calculation for Low-Dose-Rate Brachytherapy. Medical Physics, 44(6).

Klinker, C., Jett, C., Barney, C., Allan, E., Gupta, N., & Lu, L. (2017). Dosimetry Comparison of Gamma Knife and Linac Based External Beam SRS. Medical Physics, 44(6), 2964-2964.

Gupta, N., Woollard, J., Ayan, A., DiCostanzo, D., & Hintenlang, K. (2017). Transforming From a Small Academic Department Into a Premier Radiation Oncology Program. Medical Physics, 44(6), 3210-3210.

Ayan, A., Woollard, J., DiCostanzo, D., Grzetic, S., Hessler, J., & Gupta, N. (2017). Development of TG-142 Imaging QA Baselines and Imaging Performance Trending and Analysis Using a QA Data Repository for Nine Beam Matched and Dosimetrically Equivalent TrueBeams Over Two Years of Operation. Medical Physics, 44(6), 3240-3240.

Christ, D., DiCostanzo, D., Ayan, A., Woollard, J., & Gupta, N. (2017). Evaluation of a Novel Multi-Criteria Optimization Algorithm in a Commercially Available Treatment Planning System. Medical Physics, 44(6), 2903-2903.

Graeper, G., Cetnar, A., Woods, K., Gupta, N., & Weldon, M. (2017). Clinical Investigation of Auto Beam Hold and Intrafraction Motion Review. Medical Physics, 44(6), 3270-3270.

Grzetic, S., Woollard, J., Gupta, N., & Ayan, A. (2017). Calculation for TG-51’s KQ for a 2.5MV Beam. Medical Physics, 44(6), 2940-2940.

DiCostanzo, D., Ayan, A., Woollard, J., & Gupta, N. (2017). Use of Eclipse Scripting API to Ensure Plan Integrity for Patient Specific Quality Assurance. Medical Physics, 44(6).

Cetnar, A., & Gupta, N. (2017). Examining Student Conceptual Understanding of Dose in Radiation Therapy by Comparing Frameworks of Experts and Novices. Medical Physics, 44(6).

Ayan, A., Whitaker, M., Al-Hallaq, H., Hsu, S., Woollard, J., Roberts, D., Shtraus, N., Gupta, N., Moran, J. Kim, G. (2017). Automated and Streamlined KV CBCT Image QA: A Multi-Institutional Study. Medical Physics, 44(6), 3272-3272.

Mamounas, E., Bandos, H., White, J., Julian, T., Khan, A., Shaitelman, S., Torres, MA; Vicini, FA; Ganz, PA; McCloskey, SA; Paik, S; Gupta, N; Li, XA; DiCostanzo, DJ; Costantino, JP; Curran Jr, WJ; Wolmark, N. (2017). Abstract OT2-03-01: NRG oncology/NSABP B-51/RTOG 1304: A phase III superiority clinical trial designed to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to breast RT post breast-conserving surgery (BCS) will reduce invasive cancer events in patients (pts) with positive axillary (Ax) nodes and convert to ypN0 after neoadjuvant chemotherapy (NC): American Association for Cancer Research.

Mamounas, E. P., Bandos, H., White, J. R., Julian, T. B., Khan, A. J., Shaitelman, S. F., Torres, MA; Vicini, FA; Ganz, PA; McCloskey, SA; Paik, S; Gupta, N; Li, XA; DiCostanzo, DJ; Costantino, JP; Curran Jr, WJ; Wolmark, N. (2017). NRG oncology/NSABP B-51/RTOG 1304: A phase III superiority clinical trial designed to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to breast RT post breast-conserving surgery (BCS) will reduce invasive cancer events in patients (pts) with positive axillary (Ax) nodes and convert to ypN0 after neoadjuvant chemotherapy (NC). Cancer Research, 77. doi:10.1158/1538-7445.Sabcs16-Ot2-03-01

White, J., McElroy, S., Sekhon, A., Wei, L., Bazan, J., Yang, X., DiCostanzo, D., Gupta, N. and M. Knopp (2017). Abstract OT2-03-02: “Feasibility of assessing radiation response with MRI/CT directed preoperative accelerated partial breast irradiation in the prone position for hormone sensitive early stage breast cancer”, in Cancer Research 77(4 Supplement):OT2-03-02-OT2-03-02, February 2017.

Mamounas, EP; Bandos, H; White, JR; Julian, TB; Khan, AJ; Shaitelman, SF; Torres, MA; Vicini, FA; Ganz, PA; McCloskey, SA; Paik, S; Gupta, N; Li, XA; DiCostanzo, DJ; Costantino, JP; Curran Jr, WJ; Wolmark, N; (2016) “Abstract OT2-02-02: NRG Oncology/NSABP B-51/RTOG 1304: A phase III clinical trial to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to breast RT post breast-conserving surgery (BCS) will reduce invasive cancer events in patients (pts) with positive axillary (Ax) nodes who are ypN0 after neoadjuvant chemotherapy (NC)”,Cancer Research,76,4 Supplement,OT2-02-02-OT2-02-02,2016,American Association for Cancer Research

Bazan, Jose; DiCostanzo, Dominic; Majithia, Lonika; Quick, Allison Marie; Gupta, Nilendu; White, Julia R; “Rates of unacceptable variation (UV) of normal tissue constraints in patients undergoing chest wall/breast and regional nodal irradiation (RNI) in a routine clinical practice”, ASCO Annual Meeting Proceedings,33,28_suppl,67,2015,

Woods, K; Ayan, A; Woollard, J; Gardner, N; Gupta, N; “SU-FJ-53: A 3D Printed Phantom for the Use of Daily Quality Assurance Alignment Tests,” Medical Physics,43,6,3418-3418,2016,American Association of Physicists in Medicine

Woods, K; DiCostanzo, D; Gupta, N; “SU-FJ-74: High Z Geometric Integrity and Beam Hardening Artifact Assessment Using a Retrospective Metal Artifact Reduction (MAR) Reconstruction Algorithm,” Medical Physics,43, 6, 3423-3423, 2016,American Association of Physicists in Medicine

Smith, T; Ayan, A; Cochran, E; Woollard, J; Gupta, N; “,SU-G-JeP1-04: Characterization of a High-Definition Optical Patient Surface Tracking System Across Five Installations,” Medical Physics,43,6,3648-3648,2016,American Association of Physicists in Medicine

Stowe, M; Gupta, N; Raterman, B; Lu, L; “SU-G-JeP2-12: Quantification of 3D Geometric Distortion for 1.5 T and 3T MRI Scanners Used for Radiation Therapy,” Medical Physics,43(6),3662-3662,2016,American Association of Physicists in Medicine

Mamounas, EP; Bandos, H; White, JR; Julian, TB; Khan, AJ; Shaitelman, SF; Torres, MA; Vicini, FA; Ganz, PA; McCloskey, SA; Paik, S; Gupta, N; Li, XA; DiCostanzo, DJ; Costantino, JP; Curran Jr, WJ; Wolmark, N;(2016) “NRG Oncology/NSABP B-51/RTOG 1304: A phase Ill clinical trial to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to breast RT post breast-conserving surgery (BCS) will reduce invasive cancer events in patients (pts) with positive axillary (Ax) nodes who are ypNO after neoadjuvant chemotherapy (NC)”,CANCER RESEARCH,76,,,2016,”AMER ASSOC CANCER RESEARCH 615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USA”

DiCostanzo, D; Ayan, A; Woollard, J; Gupta, N; (2016) “SU-FR-12: Prediction of TrueBeam Hardware Issues Using Trajectory Log Analysis,” Medical Physics,43,6,3375-3375, 2016, American Association of Physicists in Medicine

Ayan, A; DiCostanzo, D; Woollard, J; Gupta, N; (2016) “SU-FP-43: Use of Freeware Business Intelligence Software to Trend TG-142 Compliant Linac QA Parameters,M” edical Physics, 43, 6, 3367-3368, 2016, American Association of Physicists in Medicine

Mamounas, Eleftherios P; Bandos, Hanna; White, Julia R; Julian, Thomas B; Khan, Atif J; Shaitelman, Simona Flora; Torres, Mylin Ann; Vicini, Frank; Ganz, Patricia A; McCloskey, Susan Ann; Paik,Soonmyung; Gupta,Nilendu; Li,X Allen; DiCostanzo,Dominic J; Costantino,Joseph P; Curran,Walter John; Wolmark,Norman; “NRG Oncology/NSABP B-51/RTOG 1304: Phase III trial to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to breast RT post breast-conserving surgery (BCS) reduces invasive breast cancer recurrence free interval (IBCRFI) in patients (pts) with positive axillary (PAx) nodes who are ypN0 after neoadjuvant chemotherapy (NC)”,ASCO Annual Meeting Proceedings,34,15_suppl,TPS1097,2016,

Sandu, A; Thompson, S; Ayan, A; Woollard, J; Gupta, N; “SU-FT-605: Implementation of the Conformity/Gradient Index (CGI) to Intracranial, Linac-Based Stereotactic Plans to Evaluate Possible Improvements in Treatment Planning”,Medical Physics,43,6,3603-3603,2016,American Association of Physicists in Medicine

DiCostanzo, D; Ayan, A; Woollard, J; Gupta, N; “SU-G-TeP4-08: Automating the Verification of Patient Treatment Parameters,” Medical Physics, 43, 6, 3686-3686, 2016, American Association of Physicists in Medicine

Grzetic, S; Weldon, M; Noa, K; Gupta, N; “SU-G-TeP2-09: Evaluation of the MaxFOV Extended Field of View (EFOV) Reconstruction Algorithm On a GE RT590 CT Scanner”, Medical Physics, 43 , 6 , 3665-3665, 2016, American Association of Physicists in Medicine

Woollard J, Ayan A, DiCostanzo D et al. SU-ET-468: Implementation of the TG-142 QA Process for Seven Linacs with Enhanced Beam Conformance. Medical physics 2015; 42: 3442-3442.

Woods K, Woollard J, Ayan A et al. SU-ET-234: Daily Quality Assurance for a Six Degrees of Freedom Couch Using a Novel Phantom. Medical physics 2015; 42: 3386-3386.

Stowe M, DiCostanzo D, Ayan A et al. SU-EJ-09: Image Quality Comparison and Dose Quantification for 2.5 MV. Medical physics 2015; 42: 3265-3265.

Mamounas EP, Bandos H, White JR et al. Abstract OT1-3-02: Will chest wall and regional nodal radiotherapy post mastectomy or the addition of regional nodal radiotherapy to breast radiotherapy post lumpectomy reduce the rate of invasive cancer events in patients with positive axillary nodes who convert to ypN0 af. Cancer Research 2015; 75: OT1-3-02-OT01-03-02.

Mamounas EP, Bandos H, White JR et al. NRG Oncology/NSABP B-51/RTOG 1304: Phase III trial to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to breast RT post breast-conserving surgery (BCS) will reduce invasive cancer events in patients (pts) with positive axillary (Ax) nodes who are ypN0 after neoadjuvant chemotherapy (NC). ASCO Annual Meeting Proceedings 2015; 33: TPS11112.

Hessler J, DiCostanzo D, Grzetic S et al. SU-ET-676: Reproducibility and Consistency of Two SunNuclear 3D Scanning Tanks. Medical physics 2015; 42: 3492-3492.

Gupta N, DiCostanzo D, Fullenkamp M. MO-F-CAMPUS-T-03: Data Driven Approaches for Determination of Treatment Table Tolerance Values for Record and Verification Systems. Med Phys 2015; 42: 3572.

Grzetic S, Hessler J, Gupta N et al. SU-ET-211: Comparison of Seven New TrueBeam Linacs with Enhanced Beam Data Conformance Using a Beam Comparison Software Tool. Medical physics 2015; 42: 3380-3380.

DiCostanzo D, Thompson S, Woollard J et al. An Electronic Whiteboard to Manage the Treatment Planning Process. International Journal of Radiation Oncology* Biology* Physics 2015; 93: E499-E500.

DiCostanzo D, Thompson S, Woollard J et al. MO-F-CAMPUS-T-02: An Electronic Whiteboard Platform to Manage Treatment Planning Process. Med Phys 2015; 42: 3572.

Carlson M, Hessler J, Grzetic S, Gupta N. SU-ET-324: Dosimetric Evaluation of Soft Docking Sensitivity On An INTRAOP Mobetron IORT Device. Medical physics 2015; 42: 3407-3407.

Lu, L., Gupta, N., Hessler, J., Liu, A., Weldon, M., McGregor, J., Ammirati, M., Guiou, M., Xia, F., Grecula, J., “Inhomogeneity Correction in Planning of Gamma Knife Treatments for Acoustic Schwannoma”, Medical Physics 41 (6), 351-351, (2014).

Hessler, J., Gupta, N., Rong, Y., Weldon, M., “Characterization of Radiation Dose Associated with Dark Currents During Beam Hold for Respiratory-Gated Electron Therapy”, Medical Physics 41 (6), 237-237, (2014).

Chaswal, V., Weldon, M., Gupta, N., Rong, Y., “Commissioning and Comprehensive Evaluation of the ArcCHECK Cylindrical Diode Array for VMAT QA”, Medical Physics 41 (6), 373-373, (2014).

Lu, L., Noa, K., Woods, K., Weldon, M., Gupta, N., “Image Distortion Quantification and Image Registration QA in GammaKnife Radiosurgery Using A Modus GRID3D Phantom”, Medical Physics 41 (6), 221-221, (2014).

Woods, K., Rong, Y., Weldon, M., Gupta, N., “TG142 Complied Comprehensive Commissioning and Quality Assurance Procedure for Respiratory Gating”, Medical Physics 41 (6), 386-386, (2014).

Lu, L., Bondra, K., Gupta, N., Sommerfeld, J., Pelloski, C. “Using NanoDots Dosimetry for RS 2000 X-Ray Biological Irradiator”, International Journal of Radiation Oncology, Biology, Physics, 84(3), S856 (2013). doi:10.1016/j.ijrobp.2012.07.2288

Majithia, L., Hattie, T., Weldon, M., Boyle, D., Gupta, N., Sommerfeld, J., Porcu, P., Wong, H., Siddiqui, F., Welliver, M.X., “Novel Tissue Compensation with Photon Irradiation for Cutaneous T-Cell Lymphoma With Irregular Surfaces”, International Journal of Radiation Oncology* Biology* Physics 87 (2), S684-S684 (2013).

Welliver, M., Ayan, A., Lu, L., Rong, Y., Weldon, M., Cunningham, M., Woollard, J., Gupta, N. “A New Method for Total Body Irradiation (TBI) Treatment Planning Using an “Irregular Surface Compensator”,” International Journal of Radiation Oncology, Biology, Physics, 84(3) (2012), S864. doi:10.1016/j.ijrobp.2012.07.2311

Rong, Y.; Gupta, N.; Kuhn, K.; Glass, P.; Fullenkamp, M.; Quick, A., “Respiratory-gated Deep-inspiration Breath Hold Left Breast Irradiation Incorporating Real-time 3D Surface Optical Tracking and Integrated MV Cine Acquisition,” International Journal of Radiation Oncology, Biology, Physics, 84(3), S215-S216. doi:10.1016/j.ijrobp.2012.07.559

Ayan,A; Lu,L; Rong,Y; Cunningham,M; Weldon,M; Welliver,M; Woollard,J; Gupta,N. “Feasibility of Using the “Irregular Surface Compensator’ Planning Feature of the Eclipse TPS for Total Body Irradiation (TBI) Treatment Planning.” MEDICAL PHYSICS. (Jun 2012). 39 (6). 3805-3805.
Ayan,A; Woollard,J; Gupta,N. “A Computer Program for Second Physics Manual Calculations in HDR Brachytherapy.”In: MEDICAL PHYSICS. (Jun 2012). 39 (6). 3716-3716.

Rong,Y; Jia,J; Sun,J; Gupta,N. “Establishing Comprehensive Quality Assurance Program for Volumetric Modulated Arc Therapy – Clinical Study Using Control Point Analysis Software.” In: MEDICAL PHYSICS. (Jun 2012). 39 (6). 3957-3957.

Lu,L; Gupta,N; Martin,D; Hattie,T; Carpenter,A; Weldon,M; Woollard,J. “Comparison of Acuity Cone-Beam CT Based Image Guided HDR with the Conventional CT-Simulator Based Image-Guided HDR.” In: INTERNATIONAL JOURNALOF RADIATION ONCOLOGY BIOLOGY PHYSICS. (Jan 2011). 81 (2). S909-S909.

Vade BonCoeur D, Pelloski C, Gupta N, Weldon M, Woollard J, Martin D, McGee M, Boyle D, Glass P, Werner P, Kuhn K, and Lu L, “Using Intensity Modulated Radiation Therapy for Total Body Irradiation — a Phantom Study,” Med. Phys. 38, 3678 (2011)

Durgin J, Zhang D, Weldon M, and Gupta N “Quality Assurance Utilizing 3D Dose Reconstruction for Stereotactic Lung Body Radiotherapy,” Med. Phys. 38, 3618 (2011)

Zhang D, Gupta N, Lu L, and Zhang H, “Anisotropy Function Verification of I-125 Brachytherapy Source with Film Dosimetry,” Med. Phys. 37, 3203 (2010)

Lu L, Gupta N, Zhang D, Weldon M, Wang J, Zhang H, Sundararaman I, and Huang Z, “The Comparison of Matrixx IMRT QA and MapCheck IMRT QA,” Med. Phys. 37, 3243 (2010)

Racke,Frederick,Karl; Baird,Maureen,E; Barth,Rolf; Huo,Tianyao; Yang,Weilian; Weldon,Michael; Gupta,Nilendu. “Unique Thrombopoietic Activity of Novel PKC Agonist Ingenol 3,20 Dibenzoate.” In: BLOOD. (Nov 2009). 114 (22). 1400-1400.

Lo, S.S.; Clarke, J.W.; Grecula, J.C.; McGregor, J.M.; Mayr, N.A.; Montebello, J.F.; Gupta, N, “Stereotactic Radiosurgery Alone for Patients with 1-4 Radioresistant Brain Metastases,” International Journal of Radiation Oncology, Biology, Physics, Vol. 75, Issue: 3 , pp. S256, Date: November 1, 2009

Radawski, J.D.; Nelson, A.; Clarke, J.W.; Grecula, J.C.; McGregor, J.M.; Mayr, N.A.; Gupta, N, “Stereotactic Radiosurgery with or without Whole Brain Radiotherapy of Patients with 1 to 4 Melanoma Brain Metastases.” International Journal of Radiation Oncology, Biology, Physics, Vol. 75, Issue: 3, pp. S257, Date: November 1, 2009

Li, K.; Grecula, J.C.; Montebello, J.F.; Wang, J.Z.; Gupta, N.; Lu, L.; Zhang, H.; Lo, S.S.; Mayr, N.; “Stereotactic Radiosurgery Options for Small Metastasis Brain Tumors with High Resolution Geometric Setup,” International Journal of Radiation Oncology, Biology, Physics, Vol. 75, Issue: 3, pp. S696, Date: November 1, 2009

Zhang D, Li K, Weldon M, Wang J, Zhang H, Lu L, and Gupta N “Pattern Distance Method Analysis On Potential Clinical Benefit in Using 2.5mm Width Leaf MLC-Based IMRT,” Med. Phys. 36, 2563 (2009)

Weldon M, Zhang D, Korytko T, Radawski J, and Gupta N, “Comparison of Eclipse Step-And-Shoot IMRT Plans with Direct Aperture Optimized Treatment Plans,” Med. Phys. 36, 2548 (2009)

Huang Z, Mayr N, Yuh W, Lo S, Montebello J, Lu L, Li K, Zhang H, Gupta N, and Wang J, “Junior Investigator Winner: Outcome Prediction of Cervical Cancer: Kinetic Model of Tumor Regression During Radiation Therapy,” Med. Phys. 36, 2721 (2009)

Rahman A, Montebello J, Lu L, Gupta N, Huang Z, Mayr N, and Wang J, “To Reduce Hot Dose Spots in Craniospinal Irradiation: A Two-Field IMRT Approach with Matching Beam Divergence,” Med. Phys. 36, 2658 (2009)

Martin J, Stallter B, Traeger J, Li K, Lu L, Wang J, Gupta N, Ashburn J, and Zhang H, “Reporting and Assessing Radiation Damage of Normal Structures in Radiotherapy,” Med. Phys. 36, 2641 (2009)

Yembi-Goma G, Lu L, Li K, Wang J, Zhang H, Martin D, and Gupta N, “An Optimized Protocol for Using Small Field MV Cone-Beam CT Imaging in Image-Guided Radiotherapy (IGRT),” Med. Phys. 36, 2478 (2009)

Lu L, Yembi-Goma G, Wang J, Gupta N, Li K, Zhang H, Weldon M, Huang Z, Lo S, Martin D, and Mayr N, “A Practical Method to Measure and Evaluate Different Dose Calculation Algorithms in Varian Eclipse Treatment Planning System,” Med. Phys. 36, 2597 (2009)

Li K, Wang J, Gupta N, Zhang H, Lu L, Lo S Grecula, J, and Mayr N, “Optimal Number of Blocking Beams for Plug-Modulated Gamma Knife Stereotactic Radiosurgery,” Med. Phys. 36, 2649 (2009)

Zhang, H.; Traeger, J.; Li, K.; Lu, L.; Wang, J.; Gupta, N. “Impact of Fraction Dose in Hypo-Fractionated Megavoltage Grid Therapy for Melanoma,” International Journal of Radiation Oncology, Biology, Physics, Vol. 75, Issue: 3, pp. S619-S620, Date: November 1, 2009

Zhang, D., Mayr, N., Wang, J., Derrow, A., Patel, R., Montebello, J., Kim, E.Y., Martin, D.D., Gupta, N., Yuh, W.T.C. “ Correlations of Longitudinal White Blood Cell Count with Radiation Therapy Outcome for Cervical Cancer”; International Journal of Radiation Oncology, Biology, Physics, 72(1), S366-S367(2008)

Clarke, J.W.; McGregor, J.; Grecula, J.C.; Mayr, N.A.; Wang, J.Z.; Li, K.; Gupta, N.; Cavaliere, R; “Stereotactic Radiosurgery with or without Whole Brain Radiotherapy for Patients with a Single Radioresistant Brain Metastasis,” International Journal of Radiation Oncology, Biology, Physics, Vol. 72, Issue: 1, September 1, pp. S235-S236 (2008).

Wang J, Mayr N, Zhang D, Grecula J, Zhang H, Li K, Gupta N, and Yuh W, “When the Oxygen Level Matters Mostly During Radiation Therapy of Cervical Cancer?” Med. Phys. 35, 2987 (2008).

Kong X, Zhang H, Wang J, Li K, and Gupta N, “A Feasibility Study of HDR Source Strength Verification with EDR2 and X-V Films”, Med. Phys. 35, 2730 (2008).

Li K, Kong X, Wang J, Gupta N, Weldon M, Zhang H, Zhang, D and Mayr N, “Commission of 2.5 Mm ModuLeaf MLC for Stereotactic Radiation Therapy,” Med. Phys. 35, 2762 (2008).

Gupta N, Kong X, Shukla H, Bose S, Weldon M, Mayr N, Lo S, Wang J, Li K, and Zhang H, “Development of Megavoltage Cone Beam Image Guided Radiation Therapy (IGRT) for Mini-Multileaf Collimator (mMLC) Based IMRT and Radiosurgery Applications,” Med. Phys. 35, 2695 (2008).

Gupta N, Weldon M, Kong X, Wang J, Zhang H, and Li K, “A Study On the Use of Full-Field Non-Flat Beams for IMRT Treatment,” Med. Phys. 35, 2637 (2008).

Zhang H, Law A, Wang J, Li K, Gupta N, Zhang D, Kong X, Weldon M, Mayr N, Martin D, and Meigooni A, “A Comparison of Doses Calculated by Commonly Used Algorithms in Eyeplaque Implant”, Med. Phys. 35, 2633 (2008)

Yuan, J.; Wang, J.Z.; Lo, S.; Grecula, J.C.; Ammirati, M.; Montebello, J.F.; Zhang, H.; Gupta, N;, “Hypofractionation Regimens for Stereotactic Radiotherapy of Large Brain Tumors,” International Journal of Radiation Oncology, Biology, Physics, Vol. 69, Issue: 3, November 1, 2007. pp. S470-S471

Li, K.; Wang, J.; Lo, S.; Zhang, H.; Gupta, N.; Mayr, N., “An Optimal Gamma Knife Plugging Pattern (GKPP) Treatment Planning Internet Agent,” International Journal of Radiation Oncology, Biology, Physics, Vol. 69, Issue: 3, November 1, 2007. pp. S722-S723 (2007).

Zhang H, Wang J, Mayr N, Kong X, Yuan J, Gupta N, Lo S, Grecula J, Montebello J, Martin D, and Yuh W, “Fractionated Grid Therapy in Treating Cervical Cancers: Hypo-Fractionation Or Conventional Fractionation?” Med. Phys. 34, 2567 (2007).

Wang J, Zhang D, Mayr N, Zhang H, Gupta N, Li K, and Montebello J, “A Closed Form of Linear-Quadratic Model with Reciprocal-Time for Radiation Damage Repair,” Med. Phys. 34, 2602 (2007).

Weldon M, Gupta N, and Kanellitsas C, “An Independent Verification of Dosimetry for the Leksell Gamma Knife Treatment Planning System”, Med. Phys. 34, 2416 (2007).

Yuan, J.; Wang, J.Z.; Lo, S.; Grecula, J.C.; Ammirati, M.; Montebello, J.F.; Zhang, H.; Gupta, N “Hypofractionation Regimens for Stereotactic Radiotherapy of Large Brain Tumors,” International Journal of Radiation Oncology, Biology, Physics, Vol. 69, Issue: 3, pp. S470-S471, Date: November 1, 2007

Wang, J.Z.; Mayr, N.A.; Yuh, W.T.C.; Motebello, J.; Zhang, H.; Gupta, N.; Grecula, J.; Wu, D.

“Kinetic Model of Tumor Regression During Radiation Therapy of Cervical Cancer,” International Journal of Radiation Oncology, Biology, Physics, Vol. 66, Issue: 3, Date: November 1, pp. S603, 2006

Mayr, N.A.; Koch, R.M.; Wang, J.Z.; Sammet, S.; Montebello, J.F.; Gupta, N.; Grecula, J.C.; Wu, “Intra-fractional Organ Motion of the Uterus and Tumor in Cervical Cancer Patients – Implications for Radiation Therapy Planning and Delivery,” International Journal of Radiation Oncology, Biology, Physics, Vol. 66, Issue: 3, November 1, pp. S164 (2006).

Kanellitsas, C., and Gupta, N., “A QA Device to Perform End-To-End Spatial Accuracy Tests of Target Irradiation in Stereotactic Radiosurgery ,” Med. Phys. 33, 2060 (2006).

Yuh, W T ; Mayr, N A ; Wang, J Z ; Montebello, J F ; Grecula, J C ; Wu, D H ; Edwards, S M ; Nag, S ; Gupta, N ; Knopp, M V, “The 4th Dimension of Tumor Volume: Dynamic Volumetric Tumor Regression Analysis in Cervical Cancer and Radiation Therapy Outcome”, International journal of radiation oncology, biology, physics. 63, no. 1: S215, (2005)

Mayr, N A ; Yuh, W T ; Wang, J Z ; Montebello, J F ; Nag, S ; Grecula, J ; Wu, D H ; Jarjoura, D ; Heverhagen, J ; Gupta, N ; Edwards, S M ; Knopp, M V, “Early Prediction of Treatment Outcome: Functional MR Imaging and Standard Clinical Prognostic Factors in Advanced Cervical Cancer,” International journal of radiation oncology, biology, physics. 63, no. 1, (2005): S97

Woollard, J., Gao, M., Samsami, N., Kanellitsas, C., and Gupta, N. “Commissioning of a Mobetron Electron Linear Accelerator,” Med. Phys. 32, 1992 (2005)

Gao, M., Samsami, N., Woollard, J., Kanellitsas, C., Wang, J., and Gupta, N., “A Study of the Effects of Seed Migration On Prostate Post-Seed Dose Plan Evaluation,” Med. Phys. 32, 1953 (2005)

Koc, M., McGregor, J., Grecula, J., Bauer, C. J., Gupta, N., and Gahbauer, R. A., “Gamma knife radiosurgery for intracranial metastatic melanoma: an analysis of survival and prognostic factors,” RADIOTHERAPY AND ONCOLOGY 73, S259, 2004.

Gupta, N., Feng, P., Gahbauer, R., Martinez-Monge, R., and Woollard, J., “A 3D nodal atlas and nodal involvement probabilities for head and neck cancers,” International Journal of Radiation Oncology*Biology*Physics 57, S243, 2003.

Li, Y., Woollard, J., and Gupta, N., “Dose profile measurements in a Leksell Gamma Knife using TLD- 100H thermoluminescent dosimeters,” Med Phys 30, 1480, 2003.

Gupta, N. Li, Y., Woollard, J., “A Comparison of Film Dosimeters for Small Field Profile Measurements”, Med. Phys. 29(6), p1205, 2002.

Gupta, N., Martinez-Monge, R., Fernandes, P.S., Gahbauer, R., “An Interactive Cross Sectional Nodal Atlas to Aid Clinical Target Volume(CTV) Definition in 3DRTP and IMRT”, Med. Phys. 29(6), p1217, 2002.

Grecula JC, Grever M, Gupta N, Goodman J, Barth R, Christoforidis G, Miles D, Renschler M, Maher J, Wang D, Kangarlu A, Jalil AA, Bauer C, McGregor J, Newton H, Chakeres D, Chaudhury A, Young D, Fischer B, Adams D, Balcerzak S, Ivy P, “Phase I trial of motexafin gadolinium (Gd-Tex) during G-knife boost for glioblastoma multiforme,” Clinical Cancer Research, 7: (11) 762 , Suppl. S, Nov 2001

Nag, S.; Chao, C.; Erickson, B.; Fowler, J.; Gupta, N.; Martinez, A.; Thomadsen, B., “The American brachytherapy society recommendations for low dose rate brachytherapy for carcinoma of the cervix,” International Journal of Radiation Oncology*Biology*Physics, Vol. 51, Issue: 3, Date: November 1, pp. 64, 2001

Nag S, Erickson B, Parikh S, Gupta N, Varia M, Glasgow G. The American Brachytherapy Society Recommendations for HDR Brachytherapy for Carcinoma of the Endometrium. . Radiother Oncol 55 (Suppl 1):63, 2000

Gupta, N., Albertson, B., “Errors in Isodose Calculations for Conformal Prostate Treatments using Multileaf Collimators,” Med. Phys. 25(7):A207 (1998) (abstract).

Thavendrarajah, A., Samsami, N., Gupta, N., Kanellitsas, C.K., Werner, P., Boyle, D., “Evaluation and implementation of double foucs multileaf collimator system,” Med. Phys. 24(6):1046, (1997) (abstract).

Samsami, N., Kleiman, M., Thavendrarajah, A., Gupta, N., Kanellitsas, C.K., “Penumbra comparison between double focused multileaf collimator system and divergent cerrobend blocks,” Med. Phys. 24(6):1029, (1997) (abstract).

Gupta, N., Kanellitsas, C. K., Samsami, N., “Modeling of Output Factors for Symmetric and Asymmetric Fields,” Med. Phys. 20(3): 901, (1993). (abstract)

Samsami, N., Kanellitsas, C. K., Gupta, N., Forchione, P., “Comparison of Field Size Factors of Two Siemens Accelerators producing 6 MV photon beams,” Med. Phys. 18 (3): 617, (1991). (abstract)

Kanellitsas, C. K., Samsami, N., Gupta, N., “Study of the Collimator Scatter Factor for Asymmetric Field” Med. Phys. 18 (3): 618, (1991). (abstract)

REFEREED OR JURIED PROCEEDINGS/BOOK CHAPTERS

Sumption M, Benali A, Lu L, Gupta N, Collings E. Monte Carlo Simulations of the Effect of Magnetic field on Deposited dose in Proton Therapy. Bulletin of the American Physical Society. 2023

Majithia L, Walston S, Guiou M, Gupta N, Chakravarti A. Chapter 24 – Use of neuro-imaging for radiation therapy planning. In: Newton HB, editor. Handbook of Neuro-Oncology Neuroimaging (Third Edition): Academic Press; 2022. p. 257-67.

Majithia, L., Walston, S., Guiou, M., Gupta, N., Chakravarti, A., “Use of Neuroimaging for Radiation Therapy Planning,” In: Handbook of Neuro-Oncology Neuroimaging (Second Edition), Newton, H. (Editor), Elsevier, 2016.

Chuirazzi W, Shawger R, Ayan AS, Woollard J, Gupta N, Caoa L, “Electron Beam Cherenkov Emission Measurements for Quality Assurance,” Transactions of the American Nuclear Society, Vol. 116, San Francisco, California, June 11–15, 2017

Sroka, J., Blue, T., Li, C., Hawk, A., and Gupta, N.,“Design of a Moderator Assembly Delimiter for an ABNS for BNCT,” American Nuclear Society, The Monte Carlo Method: Versatility Unbounded in a Dynamic Computing World, Chattanooga, TN, April 17-21, 2005.

Li, C., Blue, T.E., Gupta, N., “Moderator Assembly Design Assessment Using Newly-designed Neutron Field Assessment Parameters,” Eleventh World Congress on Neutron Capture Therapy (ISNCT-11), Boston, MA, Oct. 11-15, 2004, CD ROM

Li, C., Blue, T.E., Gupta, N.,“Field Assessment Using a Structure-segmented Head Phantom,”, Eleventh World Congress on Neutron Capture Therapy (ISNCT-11), Boston, MA, Oct. 11-15, 2004, CD ROM.

Li, C., Blue, T.E., Gupta, N.,“Field Assessment in BNCT Using a Structure-Segmented Head Phantom,” Trans. Am. Nucl., Vol. 90, Pittsburgh, PA (June, 2004), 328-329.

Li, C., Blue, T.E., Gupta, N., “Dose Distributions in BNCT Using a Structure-Segmented Head Phantom,” Trans. Am. Nucl. Soc. 89 (November 2003).

Hawk, A., Blue, T.E., Woollard, J., Gupta, N., “Effects of Target Thickness on Neutron Field Quality for an ABNS,” Research and Development in Neutron Capture Therapy, Proceedings of 10th Inter. Congress. on Neutron Capture Therapy, Essen, Germany, Sept. 2002, Wolfgang Sauerwein, Raymond Moss, Andrea Wittig (ed), Monduzzi Editore, pp.253-257, (2002)

Khorsandi, B., T.E., Gupta, N., Woollard, J.E, Hawk, A.E., “Material Considerations in the Design of a Moderator Assembly for an ABNS for BNCT,” Trans. Am. Nucl. Soc. 87 (2002)

Evans, J., Blue, T., Gupta, N., “Absorbed Dose Estimates with a High-Resolution Voxel-Based Head Phantom,” In: Hawthorne, et. al. (eds), Frontiers in Neutron Capture Therapy, Proceedings of the 8^th International Symposium on Neutron Capture Therapy for Cancer, Plenum Publishers, New York, (2001).

Gupta, N., Gahbauer, R., Blue, T., “Treatment Plan Evaluation in Boron Neutron Capture Therapy,” In: Hawthorne, et. al. (eds), Frontiers in Neutron Capture Therapy, Proceedings of the 8^th International Symposium on Neutron Capture Therapy for Cancer, Plenum Publishers, New York, p 201-206, (2001).

Gupta, N., Albertson, B.J., Gahbauer, R.A., Barth, R.F., and Goodman, J.H, “Dosimetry implications of BSH biodistribution study at OSU,” Proceedings of the Ninth International Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan, Oct 2-6, 2000, p141-142.

Goodman, J.H., Yang, W., Barth, R.F., Gao, Z., Boesel, C.P., Staubus, A.E., Gupta, N., Gahbauer, R.A., Adams, D.M., Gibson, C.R., Ferketich, A.K., Moeshberger, M.L., Carpenter, D.E., Bauer, W.F., Zhang, M., Wang, C.C., “BNCT of brain tumors: Biodistribution, pharmacokinetics and radiation dosimetry of sodium borocaptate in glioma patients,” Proceedings of the Ninth International Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan, Oct 2-6, 2000, p291-292.

Gupta, N., Gahbauer, R.A., Blue, T. E., Woollard, J. E., “Clinical Significance of in-phantom evaluation parameters for epithermal neutron beams in BNCT,” Advances in Neutron Capture Therapy, Vol I, Medicine and Physics, B. Larsson, J. Crawford and R. Weinreich (eds), Elsevier Science B.V., p 264-270 (1997)

Gahbauer, R. A., Gupta, N., Blue, T.E., Grecula, J., Goodman, J., Wambersie, A., “Fractionation in BNCT: What are the Issues?” Advances in Neutron Capture Therapy, Vol II, Chemistry and Biology, B. Larsson, J. Crawford and R. Weinreich (eds), Elsevier Science B.V., p 683-686 (1997)

Gahbauer, R., Gupta, N., Blue, T., Goodman, J., Grecula, J., Soloway, A. H., Wambersie, A., “BNCT: A promising area of research?” Proceedings of the 5th International Conference on Applications of Nuclear Techniques: “Neutrons in Research and Industry”, Crete, Greece (1996), SPIE Proceedings Series Vol 2867, p 12-22 (1997) (invited).

Wollard, J., Gupta, N., Blue, T., Gahbauer, R., “Neutron Field Optimization Parameters for Boron Neutron Capture Therapy,” Trans. Am. Nucl. Soc., 73:25-26 (1995)(invited).

Gupta, N., Gahbauer, R., Blue, T. E., Grecula, J., “Prediction of Normal Tissue Response in BNCT” Proceedings of the XVI International Cancer Congress, New Delhi, Nov 1994, R. S. Rao, M. G. Deo, L. D. Sanghvi, and I. Mitra, eds., Monduzzi Editore, Bologna, Italy, pp. 669-673.

Gupta, N., Blue, T. E., Kanellitsas, C. K., Gahbauer, R., “Effect of Head Size on 10B Dose Distribution for a Broad Field Accelerator Epithermal Neutron Source for BNCT,” Topics in Dosimetry and Treatment Planning for Neutron Capture Therapy, Proceedings of an International Workshop on Macro and Microdosimetry and Treatment planning for Neutron Capture Therapy, Boston, Massachusetts, Nov 1991. Advanced Medical Publishing, Madison, Wisconsin, 165-176 (1994).

Niemkiewicz, J., Gupta, N., Blue, T. E., “Calculation of the Gamma Dose from 1H[n,g]2H interactions in BNCT,” Topics in Dosimetry and Treatment Planning for Neutron Capture Therapy, Proceedings of an International Workshop on Macro and Microdosimetry and Treatment planning for Neutron Capture Therapy, Boston, Massachusetts, Nov 1991. Advanced Medical Publishing, Madison, Wisconsin, 157-164 (1994).

Blue, T. E., Wollard, J. E., Gupta, N., “A Calculation of Neutron RBE for BNCT,” Trans. Am. Nucl. Soc., 70 : 17-19(1994 )(invited).

Niemkiewicz, J., Blue, T. E., Gupta, N., “A Calculation of Neutron Flux Distributions in BNCT Using Removal-Diffusion Theory,” Trans. Am. Nucl. Soc., 70 : 13-15, (1994)(invited).

T. E., Wollard, J. E., Gupta, N., “Neutron RBE as a Function of Energy,” Proc. of the 8th International Conference on Radiation Shielding, April 24-27, 1994, Arlington, Texas.

Blue, T. E., Qu, T. X., Gupta, N., Gahbauer, R. A., “Effect of variations in the RBE on the design of an AENIF for BNCT,” Advances in Neutron Capture Therapy, Proc. of the Fifth Int. Symp. on Neutron Capture Therapy, Columbus, OH, Sept 1992, Plenum Publishing, NY, 99-103 (1993).

Gupta, N., Blue, T. E., Gahbauer, R. A. “Effect of Head Size on 10B Dose Distribution,” Transactions of the American Nuclear Society, 65: 157-158, (1992) (invited).

Niemkiewicz, J., Gupta, N., Blue, T. E., “Point Kernel 1H[n,g]2H Dose Calculations in BNCT,” Transactions of the American Nuclear Society, 65: 155-157, (1992) (invited).

Blue, T. E., Qu, T. X., Gupta, N., Gahbauer, R. A., “Monte Carlo Analysis of an Accelerator Epithermal Neutron Irradiation Facility (AENIF) for Boron Neutron Capture Therapy,” in New Horizons in Radiation Protection Shielding, Proceedings of an American Nuclear Society Topical Meeting, April 26-May 1, Richland, WA, 75-79 (1992) (invited).

OTHER PUBLICATIONS/PROCEEDINGS/ABSTRACTS

Li, C., Blue, T.E., Gupta, N., “Field Assessment in BNCT Using a Structure-Segmented Head Phantom,” American Nuclear Society Transactions, Vol. 90, Pittsburgh, PA (June, 2004), 328-329

Peng R, Baiocchi R, Carrodeguas L, Grecula J, Gupta N, Barth R, Chan K, Schmalbrock P, Moeschberger M, Caligiuri M. Combination Therapy with Antiviral Agents (GCV + AZT) plus Radiation Prolongs Survival in an Animal Model of EBV+ Primary Central Nervous System Lymphoma Associated with the Epstein-Barr Virus. American Association for Cancer Research (91st Annual Meeting of the AACR) April 1-5, 2000 San Francisco, CA

Nag S, Erickson B, Demanes J, Glasgow G, Gupta N, Orton C, Parikh S, Petereit D, Thomadsen B, Varia M,. The American Brachytherapy Society (ABS) Recommendations For High Dose Rate Brachytherapy (HDR) For Gynecological Cancers. Proceedings of the 21st International Congress of Radiology, Buenos Aires, Argentina, September 4-8, 2000; Page 246 (abstract).

Blue, T.E., Woollard, J.E., Gahbauer, R. A., Gupta, N., and Capala, J., “The Impact of Assumptions Regarding the Effectiveness of Gamma Rays in Controlling Gliomas on an In-Phantom Comparison of Neutron Fields for BNCT,”, IAEA Joint Technical Committee Meeting on Research Reactor Utilization for NCT, June 1999 (invited)

Evans, J.F., Blue, T. E., and Gupta, N., “Absorbed Dose Estimates with a High Resolution Voxel-Based Head Phantom,” Abstracts of Eighth Inter. Symp. on Neutron Capture Therapy for Cancer, La Jolla, CA, Sept. 1998, p.124(1998)

Gahbauer, R., Gupta, N., Blue, T. E., Sauerwein, W., and Wambersie, A., “Reporting of BNCT Irradiation: Application of The ICRU Recommendations To The Situation In BNCT,” Abstracts of Eighth Inter. Symp. on Neutron Capture Therapy for Cancer, La Jolla, CA, Sept. 1998, pp.102-103(1998).

Niemkiewicz, J., Blue, T. E., and Gupta, N., “Calculation Of Absorbed Dose Distributions Using Removal Diffusion Theory For BNCT Treatment Planning,” B. J. Albertson, ,” Abstracts of Eighth Inter. Symp. on Neutron Capture Therapy for Cancer, La Jolla, CA, Sept. 1998, p.151(1998)

Goodman JH, Yang W, Barth RF, Soloway AH, Gahbauer RA, Grecula J, Gupta N, Staubus AE, Blue T, Boesel C, Yates A, Moeschberger M, Carpenter DE, Gao Z-X, Wang C-C, Zhang M-Z: Early biodistribution, pharmacokinetics and toxicity of sodium borocaptate in patients with anaplastic astrocytoma/glioblastoma multiforme. Eighth International Symposium on Neutron Capture Therapy for Cancer Abstracts Sept, 1998; p 178.

Gupta, N., Gahbauer, R., Blue, T. E., Wambersie, A., “ Treatment Plan Evaluation in BNCT,” Abstracts of Eighth Inter. Symp. on Neutron Capture Therapy for Cancer, La Jolla, CA, Sept. 1998, p.159(1998)

Evans, J. F., Gupta, N., and Blue, T.E.,”A New Dose Prescription For BNCT That Includes Volume Effects”, of Radiation Research Society 456th Annual Meeting, Louisville, KY, April 25-30, 1998, pg (1998).

Nag S, Gupta N. A simple spreadsheet program for radiobiological equivalence for IORT. Revistade Medicina: Universidad de Navarra 42 (Extraordinario):23-24, 1998.(abstract)

Gupta, N., Blue, T.E., Vafai, K., Gahbauer, R. A., Dobelbower, M.C., Woollard, J. E., “Accelerator design requirements for a hospital-based BNCT facility,” Abstracts for the Fourteenth International Conference on the Application of Accelerators in Research and Industry, Denton, Texas, Nov 1996 (invited).

Gupta, N., Gahbauer, R.A., Blue, T. E., Woollard, J. E., “Clinical Significance of in-phantom evaluation parameters for epithermal neutron beams in BNCT,” Abstracts for the Seventh International Symposium on Neutron Capture Therapy for Cancer , Zurich, Switzerland, Sept, 1996, p 121. (abstract)

Gupta, N., Blue, T.E., Dobelbower, M.C., “Preliminary Testing of Moderator Assembly Prototype for an Accelerator-Based Neutron Source for BNCT,” Abstracts for the Seventh International Symposium on Neutron Capture Therapy for Cancer , Zurich, Switzerland, Sept, 1996, p 120. (abstract)

Gahbauer, R. A., Gupta, N., Grecula, J., Blue, T.E., Wambersie, A., “Fractionation in BNCT: What are the Issues?” Abstracts for the Seventh International Symposium on Neutron Capture Therapy for Cancer , Zurich, Switzerland, Sept, 1996, p 160. (abstract)

Blue, T. E., Woollard, J. E., Gupta, N., “Predicted effect of recombination on the energy dependence of an expression for an RBE of low energy neutrons,” Abstracts for the Seventh International Symposium on Neutron Capture Therapy for Cancer , Zurich, Switzerland, Sept, 1996, p 116-117. (abstract)

Blue, T.E., Dobelbower, C., Vafai, K., Gahbauer, R. A., Gupta, N., Woollard, J., “Design of an accelerator-based epithermal neutron source for BNCT,” Abstracts for the Seventh International Symposium on Neutron Capture Therapy for Cancer , Zurich, Switzerland, Sept, 1996, p 151. (abstract)

Gahbauer, R., Gupta, N., Blue, T. E., Goodman, J., Grecula, J., Soloway, A. H., Wambersie, A., “BNCT: a promising area of research?” Proceedings of the 5th International Conference on Applications of Nuclear Techniques: “Neutrons in Research and Industry”, Crete, Greece (1996) (invited).

Woollard, J. E., Blue, T. E., Gupta, N., “Effect of Target Size on an Expression for the Energy Dependent RBE of Low Energy Neutrons,” 44th Annual Mtg. of the Rad. Res. Soc., Chicago, Ill., April 1996.

Dobelbower, M. C., Blue T., E., Vafai, K., Gahbauer R. A., Gupta, N., Woollard, J. E., “Design of an Accelerator-Based Epithermal Neutron Source for BNCT,” Proc of the 16th Annual Conference on Medical Physics, Jodhpur, India, Nov 1995.

Gupta, N., Blue, T. E., and Blue, J. W.,“Engineering and Practical Considerations for Fabrication of a Moderator Assembly for an Accelerator Neutron Source for BNCT,” Proc. of First Inter. Workshop on Accelerator-Based Neutron Sources for Boron Neutron Capture Therapy, Jackson, WY, Sep. 11-14, 1994, INEL Report Conference-940976, pg 311-326 (1995).

Blue, T. E.,Woollard, J. E. , Gupta, N., and Gahbauer, R. A.,“Beam Design and Evaluation for BNCT,” Proc. of First Inter. Workshop on Accelerator-Based Neutron Sources for Boron Neutron Capture Therapy, Jackson, WY, Sep. 11-14, 1994, INEL Report Conference-940976, pg 197-212 (1995).

Woollard, J. E., Blue, T. E., and Gupta, N.,“Optimization of a Moderator Assembly for Use in an Accelerator-Based Epithermal Neutron Source for BNCT,” Proc. of First Inter. Workshop on Accelerator-Based Neutron Sources for Boron Neutron Capture Therapy, Jackson, WY, Sep. 11-14, 1994, INEL Report Conference-940976, pg 327-340 (1995).

Gupta, N., Gahbauer, R., Blue, T. E., Grecula, J., “Prediction of Normal Tissue Response in BNCT” PSBT1-19, Abstract Book I, XVI International Cancer Congress, New Delhi, Nov 1994, pp. 257.

Blue, T. E., Vafai, K., Gahbauer, R. A., Dobelbower, M. C., Evans, J. F., Gupta, N., andWoollard, J. E., “An Accelerator Neutron Source for BNCT,” Abstracts of Boron Neutron Capture Therapy Contractor/Grantee Workshop, U. S. Department of Energy, Office of Energy Research, Office of Health and Environmental Research, Germantown, NY, 13, 1994 (invited).

Blue, T. E.,Woollard, J. E. , Gupta, N., and Gahbauer, R. A.,“Beam Design and Evaluation for BNCT,” Abstract Compendium for First Inter. Workshop on Accelerator-Based Neutron Sources for Boron Neutron Capture Therapy, Jackson, WY, Sep. 11-14, 1994, p. 22 (1994).

Gupta, N., Blue, T. E. and Blue, J. W.,“Engineering and Practical Considerations for Fabrication of a Moderator Assembly for an Accelerator Neutron Source for BNCT,” Abstract Compendium for First Inter. Workshop on Accelerator-Based Neutron Sources for Boron Neutron Capture Therapy, Jackson, WY, Sep. 11-14, 1994, p.43 (1994).

Woollard, J. E., Blue, T. E., and Gupta, N.,“Optimization of a Moderator/Reflector Assembly for use in an Accelerator Based Epithermal Neutron Source for BNCT,” Abstract Compendium for First Inter. Workshop on Accelerator-Based Neutron Sources for Boron Neutron Capture Therapy, Jackson, WY, Sep. 11-14, 1994, p. 45 (1994).

Gahbauer, R., Grecula, J., Blue, T., Gupta, N., Goodman, J., Laster, B., “Analysis of compounds with respect to expected therapeutic gain in Boron Neutron Capture Therapy,” International Congress of Radiation Oncology 1993, Kyoto, Japan, June 1993.

Gupta, N., Blue, T. E., Gahbauer, R. A., “A Study on the Effect of Head Size on 10B Dose Distributions,” Abstracts of Fifth Inter. Symp. on Neutron Capture Therapy for Cancer, Columbus, OH., Sept 1992; p71 (1992).

Niemkiewicz, J., Gupta, N., Blue, T. E., “Calculation of the Gamma Dose Distributions in BNCT by the Point Kernel Method,” Abstracts of Fifth Inter. Symp. on Neutron Capture Therapy for Cancer, Columbus, OH., Sept 1992; p78 (1992).

Blue, T. E., Qu, T-X. B., Gupta, N., Gahbauer, R. A., Blue, J. W., “Effect of Variations in the RBE on the Design of an AENIF for BNCT,” Abstracts of Fifth Inter. Symp. on Neutron Capture Therapy for Cancer, Columbus, OH., Sept 1992; p48 (1992).

Gupta, N., Blue, T. E., Kanellitsas, C. K., Gahbauer, R., “Effect of Head Size on 10B Dose Distribution for a Broad Field Accelerator Epithermal Neutron Source for BNCT,” Abstracts of an International Workshop on Macro and Microdosimetry and Treatment planning for Neutron Capture Therapy, Boston, Massachusetts, Nov 1991.

Niemkiewicz, J., Gupta, N., Blue, T. E., “Calculation of the Gamma Dose from 1H[n,g]2H interactions in BNCT,” Abstracts of an International Workshop on Macro and Microdosimetry and Treatment planning for Neutron Capture Therapy, Boston, Massachusetts, Nov 1991.

ORAL PRESENTATIONS, MEETINGS AND CONFERENCES

“Building a Proton Center” Oral presentation at the AAPM Ohio River Valley Chapter Fall 2022 Meeting, Saturday, November 5, 2022 (Invited)

“AAPM International Council: Overview and Opportunities” Oral presentation at the AAPM Ohio River Valley Chapter Fall 2022 Meeting, Saturday, November 5, 2022 (Invited)

“Development of a 30-Year Proton Center” Panel presenter and discussant, National Association for Proton Therapy, 2022 National Proton Conference, Jacksonville, FL, April 3-6, 2022 (invited)

“Risk Assessment in Medicine” Plenary Session Speaker, Session: Risk Assessment Methods in Non-Nuclear Fields, 2021 International Topical Meeting on Probabilistic Safety Assessment and Analysis, American Nuclear Society, Nov 7-12, 2021. (invited)

“A parametric approach towards new proton facility shielding considerations in the era of proton FLASH therapy”, Poster with Oral Presentation at 2020 Particle Therapy Cooperative Group Online Conference, Sep 13-14, 2020

“Developing a new SBRT program”, Oral presentation at “Innovations in Program Development and Delivery Technologies for Stereotactic Body Radiosurgery” Symposium, June 1^st and 2^nd 2018, The Ohio State University, Columbus, Ohio.

“Development of TG-142 Imaging QA Baselines and Imaging Performance Trending and Analysis Using a QA Data Repository for Nine Beam Matched and Dosimetrically Equivalent TrueBeams Over Two Years of Operation”, AAPM 2017 Annual Meeting, Oral Presentation

“Standardization of QA and Automated Trajectory Log based QA for Nine Varian TrueBeams”, Oral Presentation, Automated QA Consortium Meeting, University of Michigan, Ann Arbor, June 16^th, 2016.

“Validation of a Cylindrical Scanner for Commissioning Data Collection”, Program Faculty and Oral Presenter, 9^th Annual QA and Dosimetry Symposium, Orlando, Florida, March 12^th, 2016.

“Quality and Safety Aspects of Head and Neck SBRT Planning and Delivery”, Invited Oral Presentation at Annual Conference of Association of Radiation Oncologists of India (West Bengal Chapter), Kolkata, India, January 18^th, 2015.

“Advances in Treatment and Information Technology in Radiation Oncology”, Invited Oral Presentation at HC3 Health Sciences Innovation Conference, Mumbai, India, January 17^th, 2015.

“Achieving connectivity between ARIA and Siemens Linear Accelerators”, Invited Oral Presentation at EnVision Varian and Siemens User Meeting 2013, Indianapolis, IN, Aug 3^rd

“Establishing Comprehensive Quality Assurance Program for Volumetric Modulated Arc Therapy – Clinical Study Using Control Point Analysis Software”, Oral Presentation at 54th Annual Meeting and Exhibition of the American-Association-of-Physicists-in-Medicine (AAPM), Charlotte, NC, July 2012.

“The Ohio State University experience in commissioning XKnife for Spinal Radiosurgery”, Invited Oral Presentation, 2008 Annual XKnife Users Meeting, Houston TX, July 27^th, 2008.

“Treating Ocular Melanoma with Eye Plaque Brachytherapy: COMS Or NAG Eye Plaque?,” Oral presentation at 51^st Annual Meeting of the American Association of Physicists in Medicine, Anaheim, CA, July 2009

“Gamma Knife Radiosurgery,” Presented at the 2004 Winter meeting of the American Association of Physicists in Medicine, Ohio River Valley Chapter, Jan 2004.

“A 3D nodal atlas and nodal involvement probabilities for head and neck cancers,” Presented at the 2003 Annual Meeting of the American Society for Therapeutic Radiology and Oncology, 2003.

“Intensity Modulated Radiation Therapy: Considerations for Clinical Implementation” Presented at the 2002 annual meeting of the Ohio Society of Radiologic Technologists, Worthington, Ohio, April 19^th, 2002.

“Dosimetry implications of BSH biodistribution study at OSU,” Ninth International Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan, Oct 2-6, 2000.

“Absorbed Dose Estimates with a High-Resolution Voxel-Based Head Phantom” Presented at the 8^th International Symposium on Neutron Capture Therapy for Cancer, September 13-18, 1998, La Jolla, California

“Accelerator Design Requirements for a Hospital-Based BNCT Facility” (invited) Presented at the Fourteenth International Conference on the Applications of Accelerators In Research and Industry, Nov 6-9, 1996, Denton, Texas.

“Radiosurgery – Theory and Practice” (invited) Presented at the 55th Annual Meeting of the Ohio Society of Radiologic Technologists, Columbus, OH, April 27-29, 1995

“Engineering and Practical considerations in Fabrication of a Moderator Assembly for an Accelerator Neutron Source for BNCT” Presented at the First Symposium on Accelerator Neutron Sources for BNCT, Jackson, Wyoming, September 1994.

“Dose Calculation and Normal Tissue Tolerance in Boron Neutron Capture Therapy” presented at the INEL subcontractors meeting at Seattle, Washington, Nov. 1993.

“Modeling of Output Factors for Symmetric and Asymmetric Fields,” presented at the 35th annual meeting of the AAPM, Aug 1993, Washington DC.

“A Study on the Effect of Head Size on ¹⁰B Dose Distributions” presented at the Fifth International Symposium on Neutron Capture Therapy, Sept 1992, Columbus, OH.

POSTER/PAPER PRESENTATIONS, MEETINGS AND CONFERENCES

Ayan AS,Whitaker M, Al-Hallaq HA, Hsu SH, Woollard J, Roberts D, Shtraus N, Gupta N, Moran J, Kim GG, Automated and Streamlined KV CBCT Image QA: A Multi-Institutional Study, AAPM 2017 Annual Meeting, Oral Presentation

Ayan AS, Woollard J, DiCostanzo D, Grzetic S, Hessler J, Gupta N, “Development of TG-142 Imaging QA Baselines and Imaging Performance Trending and Analysis Using a QA Data Repository for Nine Beam Matched and Dosimetrically Equivalent TrueBeams Over Two Years of Operation”, AAPM 2017 Annual Meeting, Oral Presentation

Shelby Grzetic S, Woollard J, Gupta N, Ayan AS, “Calculation for TG-51’s KQ for a 2.5MV Beam”, AAPM 2017 Annual Meeting, Poster Presentation

Woollard J, Ayan AS, DiCostanzo D, Carlson M, Gupta N, “A Review of TG-142 QA Results for Nine Dosimetrically Equivalent TrueBeams Over Two Years of Operation”, AAPM 2017 Annual Meeting, Poster Presentation

Dominic DiCostanzo D, Ayan AS, Woollard J, Gupta N, “Use of Eclipse Scripting API to Ensure Plan Integrity for Patient Specific Quality Assurance”, AAPM 2017 Annual Meeting, Oral Presentation

Gupta N, Woollard J, Ayan AS, DiCostanzo D, Hintenlang K, “Transforming From a Small Academic Department Into a Premier Radiation Oncology Program”, AAPM 2017 Annual Meeting, , Poster Presentation

Taylor W, Ayan AS, Woollard J, Gupta N, “A Computer Program for Physics Second Manual Calculation for Low-Dose-Rate Brachytherapy”, AAPM 2017 Annual Meeting, , Poster Presentation

Christ D, DiCostanzo D, Ayan AS, Woollard J, Gupta N, “Evaluation of a Novel Multi-Criteria Optimization Algorithm in a Commercially Available Treatment Planning System”, AAPM 2017 Annual Meeting, Poster Presentation

Ayan, A., Dicostanzo D., Woollard, J., Gupta, N., “Machine performance trending and analysis using a QA data repository for nine beam matched and dosimetrically equivalent Truebeams over two years of operation”, Varian Research Symposium, May 2017, Chicago IL.

Smith T. J., Ayan, A., Cochran, E., Woollard J., Gupta N., “Characterization of a High-Definition Optical Patient Surface Tracking System across Five Installations for Frameless Stereotactic Radiosurgery”, Varian Research Symposium, May 2017, Chicago IL.

Rong, Y.; Gupta, N.; Kuhn, K.; Glass, P.; Fullenkamp, M.; Quick, A., “Respiratory-gated Deep-inspiration Breath Hold Left Breast Irradiation Incorporating Real-time 3D Surface Optical Tracking” Presented at 54^th annual meeting of the American Society of Radiation Oncology (ASTRO), Boston, MA, Oct 2012.

Ayan,A; Lu,L; Rong,Y; Cunningham,M; Weldon,M; Welliver,M; Woollard,J; Gupta,N. “Feasibility of Using the “Irregular Surface Compensator’ Planning Feature of the Eclipse TPS for Total Body Irradiation (TBI) Treatment Planning.” Presented at 54th Annual Meeting and Exhibition of the American-Association-of-Physicists-in-Medicine (AAPM), Charlotte, NC, July 2012.

Ayan,A; Woollard,J; Gupta,N. “A Computer Program for Second Physics Manual Calculations in HDR Brachytherapy.” Presented at 54th Annual Meeting and Exhibition of the American-Association-of-Physicists-in-Medicine (AAPM), Charlotte, NC, July 2012.

Lu,L; Gupta,N; Martin,D; Hattie,T; Carpenter,A; Weldon,M; Woollard,J. “Comparison of Acuity Cone-Beam CT Based Image Guided HDR with the Conventional CT-Simulator Based Image-Guided HDR.” In: INTERNATIONAL JOURNALOF RADIATION ONCOLOGY BIOLOGY PHYSICS. (Jan 2011). 81 (2). S909-S909. Vade BonCoeur D, Pelloski C, Gupta N, Weldon M, Woollard J, Martin D, McGee M, Boyle D, Glass P, Werner P, Kuhn K, and Lu L, “Using Intensity Modulated Radiation Therapy for Total Body Irradiation — a Phantom Study,” 2011 Joint AAPM/COMP Meeting, Vancouver, Canada, July 31 – August 4, 2011.

Durgin J, Zhang D, Weldon M, and Gupta N “Quality Assurance Utilizing 3D Dose Reconstruction for Stereotactic Lung Body Radiotherapy,” 2011 Joint AAPM/COMP Meeting, Vancouver, Canada, July 31 – August 4, 2011.

Gupta N, Kong X, Shukla H, Bose S, Weldon M, Mayr N, Lo S, Wang J, Li K, and Zhang H, “Development of Megavoltage Cone Beam Image Guided Radiation Therapy (IGRT) for Mini-Multileaf Collimator (mMLC) Based IMRT and Radiosurgery Applications,” 50^th Annual Meeting of the American Association of Physicists in Medicine, Houston, TX, July 2008.

Gupta N, Weldon M, Kong X, Wang J, Zhang H, and Li K, “A Study On the Use of Full-Field Non-Flat Beams for IMRT Treatment,” 50^th Annual Meeting of the American Association of Physicists in Medicine, Houston, TX, July 2008.

Kanellitsas, C., and Gupta, N., “A QA Device to Perform End-To-End Spatial Accuracy Tests of Target Irradiation in Stereotactic Radiosurgery,” 48^th Annual Meeting of the American Association of Physicists in Medicine, Orlando, FL, July 2006.

Woollard, J., Gao, M., Samsami, N., Kanellitsas, C., and Gupta, N. “Commissioning of a Mobetron Electron Linear Accelerator,” 47^th Annual Meeting of the American Association of Physicists in Medicine, Seattle, Washington, July 2005.

Gao, M., Samsami, N., Woollard, J., Kanellitsas, C., Wang, J., and Gupta, N., “A Study of the Effects of Seed Migration On Prostate Post-Seed Dose Plan Evaluation,” 47^th Annual Meeting of the American Association of Physicists in Medicine, Seattle, Washington, July 2005.

Li, Y., Woollard, J., and Gupta, N., “Dose profile measurements in a Leksell Gamma Knife using TLD- 100H thermoluminescent dosimeters,” Med Phys 30, 1480, 2003.

Gupta, N. Li, Y., Woollard, J., “A Comparison of Film Dosimeters for Small Field Profile Measurements”, 44^th Annual Meeting of the American Association of Physicists in Medicine, Montreal, Canada, July 2002.

Gupta, N., Martinez-Monge, R., Fernandes, P.S., Gahbauer, R., “An Interactive Cross Sectional Nodal Atlas to Aid Clinical Target Volume(CTV) Definition in 3DRTP and IMRT”, 44^th Annual Meeting of the American Association of Physicists in Medicine, Montreal, Canada, July 2002.

Goodman, J.H., Yang, W., Barth, R.F., Gao, Z., Boesel, C.P., Staubus, A.E., Gupta, N., Gahbauer, R.A., Adams, D.M., Gibson, C.R., Ferketich, A.K., Moeshberger, M.L., Carpenter, D.E., Bauer, W.F., Zhang, M., Wang, C.C., “BNCT of brain tumors: Biodistribution, pharmacokinetics and radiation dosimetry of sodium borocaptate in glioma patients,” Ninth International Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan, Oct 2-6, 2000.

Gupta, N., Albertson, B., “Errors in Isodose Calculations for Conformal Prostate Treatments using Multileaf Collimators,” Presented at the 1998 Annual Meeting of the American Association of Physicists in Medicine, Aug 9-13, San Antonio, Texas.

Thavendrarajah, A., Kanellitsas, C., Samsami, N., Gupta, N., “Dosimetric Study of Large Electron Fields,” Presented at the 1998 Annual Meeting of the American Association of Physicists in Medicine, Aug 9-13, San Antonio, Texas..

Gupta, N., Gahbauer, R., Blue, T., “Treatment Plan Evaluation in Boron Neutron Capture Therapy,” The 8^th International Symposium on Neutron Capture Therapy for Cancer, September 13-18, 1998, La Jolla, California

Gupta, N., Blue, T.E., Dobelbower, M.C., “Preliminary Testing of a Moderator Assembly Prototype for an Accelerator-Based Neutron Source for BNCT,” Second Annual Update on Cancer Research, Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Research Institute, April 23, 1997.

Gupta, N., Gahbauer, R., Blue. T.E., Grecula J., “Prediction of Normal Tissue Response in Boron Neutron Capture Therapy,” First Annual Update on Cancer Research, Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Research Institute, January 26, 1996

Gupta, N., Blue, T. E., Blue, J. W., Gahbauer, R. A., “Moderator Assembly Fabrication Considerations for a Clinical Accelerator -Based Neutron Source for BNCT”, 37th Annual Meeting of the AAPM, July 23-27, 1995, Boston, MA.

Gupta, N., Kanellitsas, C. K., Thavendrarajah, A., “Evaluation and Testing of a Commercial Tissue Compensator System”, 37th Annual Meeting of the AAPM, July 23-27, 1995, Boston, MA.

Thavendrarajah, A., Kanellitsas, C. K., Werner, P., Samsami, N., Gupta, N., Bauer, C., Goodman, J., “Error in Radiosurgery Treatment Planning due to Incomplete CT Scanning of the Skull”, 37th Annual Meeting of the AAPM, July 23-27, 1995, Boston, MA.

Gupta, N., Gahbauer, R., Blue, T., Grecula, J. “Prediction of Normal Tissue Response in BNCT” Presented at the XVI International Cancer Congress, New Delhi, Nov 1994

Gupta, N., Kanellitsas, C. K., Samsami, N., “Modeling of Output Factors for Symmetric and Asymmetric Fields,” Presented at the 35th annual meeting of the AAPM, Aug 1993, Washington DC.

Gupta, N., Blue, T. E., Kanellitsas, C. K., Gahbauer, R., “Effect of Head Size on 10B Dose Distribution for a Broad Field Accelerator Epithermal Neutron Source for BNCT” Presented at the International Workshop on Macro and Microdosimetry and Treatment planning for Neutron Capture Therapy, Boston, Massachusetts, Nov 1991.

SEMINARS/CONTINUING EDUCATION

“Introduction to Proton Therapy” – Internal presentation for OSUWMC/OSUP Finance teams, June 15, 2022.

“Residency Education Management using Typhongroup’s AHST system”, SDAMPP Annual Meeting, July 13th, 2019, San Antonio, TX.

“Tracking Longer Term Safety and Treatment Effectiveness from Technical Delivery of Radiotherapy”, Department of Radiation Oncology Grand Rounds, The Ohio State University, October 17, 2019. (CME and SAMS credit approved)

“Evolution of Treatment Planning in Radiation Oncology”, Department of Radiation Oncology Grand Rounds, The Ohio State University, May 10, 2018. (CME and SAMS credit approved)

“Evolution of Treatment Planning in Radiation Oncology”, Department of Nuclear Engineering Seminar, The Ohio State University, Feb 28, 2018.

“Overview of Radiation Oncology QA Processes: QA Standardization and Automated Trajectory Log based QA for Nine Varian TrueBeams”, Invited Speaker, Department of Radiation Oncology, Tata Medical Center, Kolkata, July 2016

“Consistency of a Cylindrical Scanner for Commissioning Seven Varian TrueBeams”, Invited Speaker, Sun Nuclear Corporation educational event in conjunction with ASTRO, October 19^th, 2015.

“Medical Physics as a Career”, Presented at the Ohio State University, Department of Physics as part of the Physics 2095 Seminar Course, September 17^th, 2012.

“Clinical Proton and Heavy Particle Therapy Systems” Joint Colloquium for Department of Physics and School of Medicine, Ohio University, Athens, Ohio, Nov 3^rd, 2005.

“Moderator assembly design assessment using newly-designed neutron field assessment parameters and a structure-segmented head phantom”, Mini-symposium on Boron Neutron Capture Therapy, The Ohio State University, Nov 23^rd, 2004.

“Physics of Brachytherapy”, Brachytherapy Workshop conducted at the 13^th Annual Scientific Meeting of the Singapore Radiological Society, Tan Tock Seng Hospital, Singapore, 21-22 February 2004.

“Dosimetry of Brachytherapy and Treatment Planning”, Brachytherapy Workshop conducted at the 13^th Annual Scientific Meeting of the Singapore Radiological Society, Tan Tock Seng Hospital, Singapore, 21-22 February 2004.

“Brachytherapy Quality Assurance”, Brachytherapy Workshop conducted at the 13^th Annual Scientific Meeting of the Singapore Radiological Society, Tan Tock Seng Hospital, Singapore, 21-22 February 2004.

“Physics of Intravascular Brachytherapy”, Brachytherapy Workshop conducted at the 13^th Annual Scientific Meeting of the Singapore Radiological Society, Tan Tock Seng Hospital, Singapore, 21-22 February 2004.

“Physics for Prostate Brachytherapy”, Brachytherapy Workshop conducted at the 13^th Annual Scientific Meeting of the Singapore Radiological Society, Tan Tock Seng Hospital, Singapore, 21-22 February 2004.

“Introduction to Radiation Oncology and Overview of the OSU Nodal Atlas Project” Joint Nuclear Engineering Seminar, The Ohio State University & University of Cincinnati, Apr 8^th 2003.

“Introduction to Radiation Oncology and Overview of the OSU Nodal Atlas Project” Biomedical Engineering Seminar, The Ohio State University, Nov 26^th 2002.

“CT Simulation”, Radiation Oncology Continuing Education In-service Seminar, Division of Radiation Oncology, Ohio State University, January ’2002.

“Treatment Plan Evaluation Tools”, Radiation Oncology Continuing Education In-service Seminar, Division of Radiation Oncology, Ohio State University, March ’2002.

“IMRT: Considerations for Clinical Implementation” Radiation Oncology Continuing Education In-service Seminar, Division of Radiation Oncology, Ohio State University, February 28 ’2001.

“Computers in Radiation Oncology”, Radiation Oncology Continuing Education In-service Seminar, Division of Radiation Oncology, Ohio State University, March ’2000.

“Computer Networking in Radiation Oncology” Radiation Oncology Continuing Education In-service Seminar, Division of Radiation Oncology, Ohio State University, September 97’.

“TMS Implementation at OSU” Radiation Oncology Research Seminar, Division of Radiation Oncology, Ohio State University, April 97’.

“Use of Interchangeable Blocking Trays” Radiation Oncology Research Seminar, Division of Radiation Oncology, Ohio State University, March ’97.

“MLC Implementation at OSU” Radiation Oncology Research Seminar, Division of Radiation Oncology, Ohio State University, December ’96.

“MLC Implementation at OSU Part II” Radiation Oncology Research Seminar, Division of Radiation Oncology, Ohio State University, January ’97.

“Radiosurgery” Presented at a combined meeting of the Marion Chapter of the Ohio Society of Radiologic Technologists and the American Society of Radiologic Technologists, Marion, Ohio, Oct 3, 1995.

“Instrumentation in Medical Physics” Institute of Electronics and Electrical Engineers (IEEE) Seminar delivered at the Indian Institute of Technology, Kharagpur branch, October 1994.

CURRENT AND PREVIOUS SUPPORT

Physics PI: Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia (PREVENT), PI – Arnab Chakravarti, Multi-Institution Trial open for accrual nationally (ClinicalTrials.gov Identifier: NCT04466683), funded by Varian Medical Systems
Physics PI: Low Dose Whole Lung Radiation Therapy for Patients With COVID-19 and Respiratory Compromise (VENTED) PI – Arnab Chakravarti, Institutional trial open for accrual (ClinicalTrials.gov Identifier: NCT04427566).
Co-PI: Preliminary Feasibility Study for Evaluation of Real Time Treatment Planning for Intraoperative Electron Beam Radiotherapy, INTRAOP MEDICAL CORPORATION (Grant# GRT00054081), PI: Ahmet S. Ayan, Co-PIs: Nilendu Gupta and Jeffrey Woollard – 2018-2020 (grant recently completed)
Physics PI: NRG Oncology/NSABP B-51/RTOG 1304 (PI: White): Phase III trial to determine if chest wall and regional nodal radiotherapy (CWRNRT) post mastectomy (Mx) or the addition of RNRT to breast RT post breast-conserving surgery (BCS) will reduce invasive cancer events in patients (pts) with positive axillary (Ax) nodes who are ypN0 after neoadjuvant chemotherapy (NC).

Key Personnel: OSU 15032 (PI: Williams) A Pilot Trial if Stereotactic Body Radiation Therapy (SBRT) to Induce Tumor Hyperemia in Combination with Transarterial Chemoembolization (TACE) for Unresectable Hepatocellular Carcinoma. Funded by Varian Medical Systems

Key Personnel: (PI: White) Feasibility of assessing radiation response with MRI/CT directed preoperative accelerated partial breast irradiation in the prone position for hormone responsive early breast cancer. Funded by Susan G Komen Breast Cancer Foundation.

PI “Neurobehavioral Late-Effects in Pediatric Brain Tumors” OSU Subcontract from Childrens Hospital Medical Center, Cincinnati, OH for NIH Grant 1 R01 CA112182-01 for period 3/22/2005 – 3/22/2010 for Total Cost $ 2,177,486. OSU subcontract is for $102,545 total cost. 5% time

“An Accelerator Neutron Source for BNCT” T. E. Blue and K. Vafai Co-PI’s, Gupta and R. A. Gahbauer, Co-Investigators, from Department of Energy. Renewed grant for the period 6/1/96 to 2/28/05, $630,000 total costs. I had a separate subaccount RF Project # 732842 for $ 39,006.

Co-Investigator: Phase I Study of Gadolinium Texaphyrin in Patients with Glioblastoma Multiforme in Combination with Stereotactic Gamma Knife Radiosurgery & External Beam Radiotherapy; (includes correlative studies of MR imaging with 8 Tesla magnet & tumor / normal brain gadolinium concentration measurements) Principal Investigator: John Grecula, M.D. Project funded by National Cancer Institute through Grant # Phase I U01 CA 76576-01(Aug 1999 – Oct 2003); this project received approximately 1.5% of total Phase I grant funding (0.015 x $1,480,933 = $22,214)

Co-Investigator: Phase I Study of Gadolinium Texaphyrin in Patients with Glioblastoma Multiforme in Combination with Stereotactic: Phase I Study of Radiosensitization with Gadolinium Texaphyrin Preoperatively in Stage IIIA Resectable Non Small Cell Lung Carcinomas in Combination with Postoperative Cisplatin / Taxol Chemotherapy. (includes correlative studies with MR imaging, and tumor / normal brain gadolinium concentration. Principal Investigator: John Grecula, M.D. Project was funded by National Cancer Institute through Grant # Phase I U01 CA 76576-01 (Sept 1999-Oct 2003); project received approximately 1.5% of total Phase I grant funding (0.015 x $1,480,933 = $22,214)

“Pharmacokinetics and Biodistribution for Sodium Boro Captate in Patients with Anaplastic Astrocytomas/Glioblastoma Multiforme” J. Goodman & R. F. Barth Co-PI’s, R. A. Gahbauer, A. H. Soloway, A. E. Staubus, Gupta, T. E. Blue, C. P. Boesel, J. Grecula, M. Moeschberger, Co-Investigators, from Department of Energy. Radiation Oncology has a separate budget account for $ 54,186 total cost per year. Project ended at the end of 2000.

CLINICAL TRIALS

PI: New workflow validation for accelerator-based stereotactic radiosurgery/radiotherapy of brain tumors using MR imaging obtained in treatment position- under IRB Review

Co-Investigator: (PI:Blakaj) Multi-Institutional Retrospective Analysis of Radiation Oncology Patient Treatment Records to Define Practice Norms for Care Pattern Parameters and Development of Comparison Metrics for Head and Neck Patients.

PI: Review of Discourse in Oral Examinations for Medical Physics

PI: Validation of intra-fraction motion review for prostate patients with electromagnetic transponders

PI: Examining Students’ Conceptual Understanding of Dose in Radiation Therapy by Comparing Frameworks of Experts and Novices

PI: Review of Lung Tumor Statistics from Radiation Therapy Patients

Co-Investigator: (PI: Bazan) OSU-14091: A PHASE II TRIAL COMBINING HYPOFRACTIONATED RADIATION BOOST WITH CONVENTIONALLY-FRACTIONATED CHEMORADIATION IN LOCALLY ADVANCED NON-SMALL CELL LUNG CANCER NOT SUITABLE FOR SURGERY

Physics Co-PI: OSU-13282 “Feasibility Of Assessing Radiation Response With MRI/CT Directed Preoperative Accelerated Partial Breast Irradiation In The Prone Position For Hormone Responsive Early Stage Breast Cancer.” (PI: White)

Co-Investigator: (PI: Bazan) OSU-16106 – Multi-Institution Phase II Trial of Intraoperative Electron Beam Radiotherapy Boost at the Time of Breast Conserving Surgery with Oncoplastic Reconstruction in Women with Early-Stage Breast Cancer

Co-Investigator: (PI: Welliver) An Institutional Review of Radiation Toxicities after Myeloablative Conditioning Regimens Prior to Allogeneic Hematopoietic Stem Cell Transplantation.

Co-Investigator: (PI: Quick) An Institutional Review of Needle Applicator Displacement during High-Dose Rate Interstitial Implants

Co-Investigator: (PI: Bazan)Regional Nodal Irradiation in Patients with Breast Cancer: A Feasibility Study of Achieving the Normal tissue Constraints on NSABP B51/RTOG 1304

Co-Investigator: (PI: Williams) A phase II trial combining hypofractionated radiation boost with conventionally – fractionated chemoradiation in locally advanced non-small cell lung cancer not suitable for surgery.

Co-Investigator: (PI: Welliver) OSU-13219: A feasibility study of organ-sparing marrow-targeted irradiation (OSMI) to condition patients with high-risk hematologic malignancies prior to allogenic hematopoietic stem cell transplantation.

Co-Investigator: (PI: Welliver)A pilot study of pleural photodynamic therapy for patients with pleural malignancy.

Co-Investigator: (PI: Schmalbrock) Radiology research rotation (R-3) program protocol

Key Personnel: (PI: Williams)A pilot study to evaluate tumor microenvironment changes after stereotactic body radiation therapy using functional MRI.

GRADUATE Committee Assignments

Category M Graduate Faculty in Nuclear Engineering, 1996-present

GRADUATE STUDENTS ADVISED

YiPeng Li, Nuclear Engineering Graduate Student, M.S. 2002.

GRADUATE COMMITTEE PARTICIPATION

Lance Rakovan, August 1996, “Neutron Dosimetry Using Aqueous Solutions of Lithium Acetate”, M.S. Exam and thesis committee

Angela Brown, August 1996, “Using MCNP4a to Model a High Purity Germanium Detector”, M.S. Exam and thesis committee

Michael Reed, July, 1997, “Determination of the absorbed dose from an Accelerator-Based Neutron Source for Boron Neutron Capture Therapy using the Paired Ion Chamber Technique”, M.S. Exam and thesis committee

Albert Vest, September 1997, “Thermal neutron flux measurements in an anthropomorphic brain phantom”, M.S. Exam and thesis committee

Kinga Krobl, February 1999, “TLD-700 as a Mixed Field Dosimeter”, M.S. Exam and thesis committee.

Chenguang Li, August 2003, “A moderator assembly evaluation method for an ABNS for boron neutron capture therapy based on absorbed dose calculations using a high-resolution voxel-based head phantom”, M.S. Exam and Thesis Committee

Josh Sroka, March 2005 “Examination of a delimiter design for an ABNS for BNCT” M.S. Exam and Thesis Committee.

Carl Willis, June 2005 “Neutronics and shielding design of an accelerator-based neutron source for neutron activation analysis”, M.S. Exam and Thesis Committee

Michael Orr, March 2000, Ph.D. Candidacy Exam Committee.

Chad Mitchell, August, 2003, Ph.D. Candidacy Exam Committee.

Georgeta Mihai, Autumn 2005, Ph.D. Candidacy Exam Committee.

David Breuning, 2010, “A Low-Level Radioactive Waste Management Program for Activated Waste from the GE PETrace™ Cyclotron”, M.S. Exam and Thesis Committee.

Sara Lim, 2014, “Low Energy X-ray Radiosensitization Activated with High-Z Elements”, Ph.D. Thesis Committee Member, Candidacy Exam Committee Member.

Ashley Cetnar, Fall 2020, Ph.D. Thesis Committee Member, Candidacy Exam Committee Member.

TRAINEES ADVISED/MENTORED

Jeff Woollard, PhD – Medical Physics Resident 2003 – 2005

Mingcheng Gao PhD – Medical Physics Resident 2004 – 2006

Michael Weldon MSc- Medical Physics Resident 2006 – 2008

Xiang Kong MS – Medical Physics Resident 2006 – 2008

Isai Sunderaraman MS – Medical Physics Resident 2008 – 2010

Dongqing Zhang PhD – Medical Physics Resident 2009 – 2011

James Durgin – MS – Medical Physics Resident 2010 – 2012

Margaret Cunningham MS – Medical Physics Resident 2011 – 2013

Eric Cochran Ph.D. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident 2012 – 2014

Kate Noa, MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident 2012 – 2014

Kyle Woods, MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2013-2015

Andreea Sandu MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2014-2016

Malorie Stowe MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2014-2016

Josh Hessler MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2015-2017

Shelby Grzetic MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2015-2017

Timothy Jordan Smith MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2015-2017

Gavin Graeper MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2016-2018

William Taylor MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2016-2018

Kelley Nealon MS – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2017-2019

Yuting Li Ph.D. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2017-2019

Angela Steinmann Ph.D. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2018-2020

Victoria Gee M.S. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2018-2020

Sagarika Jain M.S. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2019-2021

Samantha Morelli M.S. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2019-2021

Amanda Swanson M.S. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2020-2022

Joshua Mathews Ph.D. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2020-2022

Kelsey Bittinger M.S. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2021-2023 (expected)

Joseph Scotto, M.S.. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2021-2023 (expected)

Charles Zimmerman M.S. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2022-2024 (expected)

Olalekan Shehu M.S. – Clinical Instructor, House Staff, Radiation Oncology, Medical Physics Resident – 2022-2024 (expected)

TEACHING ACTIVITIES

University Courses Taught

Quarter/Year	Course Number, Title, Credit Hours
Spring 1997	NE 999, Nuclear Engineering Research, 2 Credit Hours Call # 17509-5
Autumn 1997	Computer Theory, 1 credit hour Radiation Therapy Program *
Spring 1998	Brachytherapy, 2 credit hour Radiation Therapy Program *
Autumn 1998	Computer Theory, 1 credit hour Radiation Therapy Program *
Spring 1999	Brachytherapy, 2 credit hour Radiation Therapy Program *
Winter 1999	RAD 793.02 Individual Studies in Radiology, 2 Credit Hours Call # 18257-8
Autumn 1999	Computer Theory, 1 credit hour Radiation Therapy Program *
Spring 1999	NE 505, Introduction to Nuclear Science & Eng, 3 Credit Hours
Spring 2000	Brachytherapy, 2 credit hour Radiation Therapy Program *
Spring 2000	NE 505, Introduction to Nuclear Science & Eng, 3 Credit Hours
Autumn 2000	Computer Theory, 1 credit hour Radiation Therapy Program *
Autumn 2000	NE 505, Introduction to Nuclear Science & Eng, 3 Credit Hours
Spring 2001	Brachytherapy, 2 credit hour Radiation Therapy Program *
Summer 2001	NE 999, Nuclear Engineering Research, 5 Credit Hours Call # 16403-6
Autumn 2001	Computer Theory, 1 credit hour Radiation Therapy Program *
Autumn 2001	RAD 670, Medical Radiation Physics, 2 Credit Hours Call # 16843-6
Autumn 2001	NE 505, Introduction to Nuclear Science & Eng, 3 Credit Hours
Autumn 2001	RAD 850.26 Advanced Topics in Rad Oncology, 1 Credit Hour Call # 16857-4
Autumn 2001	RAD 999, Radiology Research, 4 Credit Hours Call # 20360-2
Winter 2002	NE 999, Nuclear Engineering Research, 1 Credit Hour Call # 14127-7
Winter 2002	RAD 793.02 Individual Studies in Radiology, 2 Credit Hours Call # 16606-5
Winter 2002	RAD 999, Radiology Research, 1 Credit Hour Call # 19642-7
Autumn 2002	RAD 670, Medical Radiation Physics, 2 Credit Hours
Autumn 2002	Computer Theory, 1 credit hour Radiation Therapy Program *
Winter 2003	Physics II, 2 credit hour Radiation Therapy Program *
Autumn 2003	Computer Theory, 1 credit hour Radiation Therapy Program *
Winter 2004	Brachytherapy, 2 credit hour Radiation Therapy Program *
Autumn 2004	Computer Theory, 1 credit hour Radiation Therapy Program *
Winter 2005	Physics I, 2 credit hour Radiation Therapy Program *
Spring 2005	Quality Assurance in Radiation Therapy, 1 credit hour Radiation Therapy Program *
Spring 2005	RAD 670, Medical Radiation Physics, 2 Credit Hours Call # 17174-6
Autumn 2006	RAD 670, Medical Radiation Physics, 2 Credit Hours Call # 18118-1
Winter 2006	Physics I, 2 credit hour Radiation Therapy Program *
Autumn 2007	NE606, Radiological Safety, 3 credit hours, Call # 15602-1
Autumn 2007	Brachytherapy, 2 credit hour Radiation Therapy Program *
Autumn 2008	RAD SCI ??, Brachytherapy, 2 Credit Hours
Winter 2008	RAD SCI 481, Physics I, 3 Credit Hours, Call # 18584-2
Winter 2008	NE880, Advanced Topics in Radiation Effects, 3 Credit Hours, Call # 15290-4
Winter 2009	RAD SCI 481, Physics I, 3 Credit Hours, Call # 18678-3
Autumn 2010	RADSCI 530, Quality Management, 4 Credit Hours
Autumn 2010	RADSCI 595, Brachytherapy, 2 Credit Hours
Winter 2010	RADSCI 481, Physics I, 3 Credit Hours, Call #
Summer 2010	RADSCI 482, Physics II, 3 Credit Hours, Call #
Autumn 2011	RADSCI 595 Brachytherapy, 3 Credit Hrs.
Summer 2012	RADSCI 4478, Brachytherapy, 3 Credit Hrs.
Autumn 2012	RADSCI 4482, Physics II, 3 Credit Hours
Winter 2013	RADSCI 3471, Rad Physics, 3 Cr. Hrs (taught part of course)
Fall 2013	RADSCI 4482, Rad Physics II, 3 Cr. Hrs
Fall 2014	RADSCI 4482, Rad Physics II, 3 Cr. Hrs – 9 students- 100%
Spring 2015	RADSCI 3471, Intro Rad Physics, 3 Cr. Hrs, 23 Students – 10%
Fall 2015	RADSCI 4482, Rad Physics II, 3 Cr. Hrs – 10 students- 100%
Spring 2016	RADSCI 3471, Intro Rad Physics, 3 Cr. Hrs, 23 Students – 10%
Fall 2016	RADSCI 4482, Rad Physics II, 3 Cr. Hrs – 10 students- 100%
Fall 2017	RADSCI 4482, Rad Physics II, 3 Cr. Hrs – 10 students- 100%
Fall 2018	RADSCI 4482, Rad Physics II, 3 Cr. Hrs – 10 students- 100%
Fall 2019	RADSCI 4482, Rad Physics II, 3 Cr. Hrs – 11 students- 100%
Fall 2020	RADSCI 4482, Rad Physics II, 3 Cr. Hrs – 10 students- 100%

* The Radiation Therapy Program was a 1 Year certificate program accredited by the Joint Committee on Education in Radiologic Technology, offered by the James Cancer Hospital and Solove Research Institute. This program has been converted into a Baccalaureate program through the School of Allied Medical Professions (College of Medicine) starting summer 2008.

Teaching for Residency Program
Radiation Physics: I have team taught the Radiation Physics class for our Radiation Oncology Residency Program since my hire in 1998. I have taught anywhere between 25% to currently about 10% of this class. I have been the course director for this course since 2007
Radiation Physics Didactic Course for PGY IV Residents: Me and one other colleague Jeff teach this yearlong in-depth physics review course meeting 1 hr per week with our PGY4 residents to prepare them for their Physics Boards. I teach about 50% of this course and Jeff and I have created this curriculum and teach it using Carmen since 2018. This course has typically 2 to 3 PGY4 residents and since we have started this course the physics board pass rate has been 100%.
Radiation Biology: I have taught two lectures for the Radiobiology didactic series since its inception.

Other Teaching Activities:

Symposium Co-Director (National audience): Innovations in Program Development and Delivery Technologies for Stereotactic Body Radiosurgery, June 1^st and 2^nd 2018, The Ohio State University, Columbus, Ohio. 100 attendees expected. (7.49 Self-assessment module- SAMS credits approved for Radiation Oncologists and Medical Physicists by the ABR, 15.82 MPCEC credits, 13 Cat A credits through ASRT, 13 MDCB credits)
Symposium Co-Director (National audience): Innovations in Immobilization and Patient Setup, May 19^th& 20^th 2017, The Ohio State University, Columbus, Ohio. 100 attendees. (12.32 MPCEC credits, 13 Cat A credits through ASRT, 13 MDCB credits)
Course Director: Introduction to Radiation Oncology, 2 day hands on introductory course offered by the Department of Radiation Oncology for Varian Medical Systems employees for onboarding. Course offered two times thus far, and will be offered 5 times a year going forward.
Course Director: Optical Surface Monitoring Systems, 2 day hands on course on commissioning, quality assurance, and clinical implementation of optical tracking systems for complex radiotherapy treatments, offered by the Department of Radiation Oncology for Medical Physicists, Therapists, and Dosimetrists.
Course Director: Expedited Truebeam Clinical Commissioning, 3 day hands on course on commissioning, quality assurance, and clinical implementation of multiple radiotherapy linear accelerators, offered by the Department of Radiation Oncology for Medical Physicists.
Invited Teaching Faculty: 13^th Annual Scientific Meeting of the Singapore Radiological Society, Tan Tock Seng Hospital, Singapore, 21-22 Feb 2004. Conducted two day workshop with Dr. Subir Nag, and delivered half of the lectures
Invited Teaching Faculty: Kolkata Brachytherapy Workshop, Nov 27^th 2007, at Calcutta Club. Jointly organized by The Radiation Oncology Departments of Calcutta Medical College and Vivekananda International Health Center. Conducted one day workshop with Dr. Subir Nag, and delivered half of the lectures

Curriculum Development

Annual Symposium: For the past two years I have co-directed a National Symposium that the department has hosted as part of increasing the national recognition for the Radiation Oncology International Training Center. Our 2017 symposium was on “Innovations in Immobilization and Patient Setup”, with an audience of about 100 Radiation Therapists, Radiation Dosimetrists, Medical Physicists, Radiation Oncologists and Radiation Oncology Vendors. Our 2018 symposium was on “Innovations in Program Development and Delivery Technologies for Stereotactic Body Radiosurgery” for a similar audience and attended by about 100 attendees as well. I have dedicated a lot of effort with my co-director, our organizing committee, and the OSU James-CCC conference management team to develop curriculum, identify speakers, organize hands-on labs, getting continuing education credits approved for each of the attendee types, and executing the conference.

For the past three years (2015 – present) I have worked closely with department leadership to lead the development of curriculum and hands-on training programs for several professional training programs as part of the Department of Radiation Oncology International Training Center, and seen them through execution and continuation of development of curriculum. The Radiation Oncology International Training Center is a unique facility that houses the only non-clinical Linear Accelerator in the nation dedicated for clinical training within clinical spaces. So far the courses that have been developed and are being taught on a regular basis are: a) Introduction to Radiation Oncology – a two day introductory course for members of the radiation oncology industry; b) Optical Surface Monitoring Systems – a two day course on commissioning, QA and implementing a clinical program around optical tracking systems in advanced radiotherapy practice; c) Clinical Truebeam Commissioning – a three day course on expedited and beam matched commissioning of multiple linacs and development of a robust QA program for a multi-linac department. Courses under development include a) VMAT and Portal Dosimetry commissioning school; b) Imaging based Brachytherapy planning, QA and delivery clinical school; and c) Prone Breast Radiotherapy clinical school.

Over the past decade I have developed and implemented a Medical Physics Clinical Residency Education Program for Radiation Oncology at the James Cancer Hospital. This is a two-year residency program integrated with Graduate Medical Education program at The Ohio State University, College of Medicine. We are currently funded for four positions by the James Cancer Hospital and GME. The residency program was accredited by the Commission on Accreditation of Medical Physics Educational Programs in 2012 initially for five years, and we have been re-accredited in 2017 for another five years. The program has constantly evolved and developed over the past years. Accomplishments include a) I have implementing a customized version of a commercial web based competency tracking and evaluation software for electronically managing the residency program, b) introduced an application database to manage, triage, and track applications coming into the program, as well as automate the correspondence process to candidates, c) introduced clickers for residency teaching, d) introduced a very rigorous annual curriculum review and change process, which includes a program evaluation by all residents and faculty and identification of strengths and areas to improve which is reviewed and managed and acted upon by our curriculum review committee. In 2015 we completed an agreement with the US Armed Services to host one medical physics resident every other year from the armed services. The Medical Physics Residency Program has graduated its first resident in June 2005, and has graduated 18 residents thus far.

I have been the course director for the Physics Course for the Radiation Oncology Residency Program since 2007. I have helped evolve the class constantly to streamline the education of our residents. I introduced clickers into our teaching and assessment of learning for the residents.

In 2008, the Radiation Therapy Program was converted from a 1 Year certificate program accredited by the Joint Committee on Education in Radiologic Technology, offered by the James Cancer Hospital and Solove Research Institute into a Bachelors program through the College of Allied Medical Professions. During this process I worked with the program director to re-design the radiation physics, brachytherapy, and Quality Assurance portion of the didactic coursework, create content and the core course requirements, which lead to the creation of the following courses RASCI 481, RASCI 482, RADSCI 530, and RADSCI 595. I have taught a majority of these courses since their creation. These courses and their content are being further developed changed since last year as part of the semester migration of the program. As part of this process I have worked with the program director and program coordinator to evaluate and change the Radiation Physics course content and the text book this year. In 2012, with OSU migrating to the Semester system, I participated in re-mapping all the physics classes and content into the Semester calendar.

Starting Fall 2001 I started teaching Radiology 670 (Radiation Therapy Physics). This course was not taught for several years. I re-designed the curriculum, to change the scope and depth of teaching, since the intended audience of the course has changed over the years. The interest of students in learning Radiation Physics come either from engineering students like Nuclear Engineering which has a Medical Applications track that include Medical Physics and Health Physics. I am a graduate faculty in Nuclear Engineering, and am in their Medical Applications Faculty Core. The other group of students interested in this course are students in biological sciences who use/intend to use radiation for their research and want to learn more about the physics of therapeutic radiation beams. I have redesigned the course to cater to the need of both these groups. I have incorporated handouts and other materials to better cover the specific needs all the backgrounds.

Since my hire in this department I have developed and taught two courses Brachytherapy and Computer Theory for the Radiation Therapy Program. Brachytherapy was a previously taught course, which I have re-designed to make it completely based on a teaching packet that I hand out. This was done to tailor the class completely to the needs of the students. Computer Theory was a class that was introduced by me at the request of the Program Director. This 1 credit course and its curriculum was designed to teach the students the basics of computers and more importantly to teach the basics of the electronic charting environment that we are in today, including databases, networking and the worldwide web. In order to make the class more hands on and appealing to students I have introduces over the years several projects and labs that give them a hands-on exposure to computers in radiation oncology. Both these classes have now been absorbed in to the physics classes taught as part of the Semester curriculum in 2012.

In 2004 I have developed with one of my clinical colleagues a series of lectures to constitute a Professional Brachytherapy Workshop. The workshop consists of closely coordinated series of didactic lectures on the clinical and physics/dosimetry aspects of Brachytherapy practice for different sites as well as lectures on basic brachytherapy physics and quality assurance. The intended audience for these lectures is Radiation Oncologists and Medical Physicists who would like to get trained in the clinical use Brachytherapy. The workshop was intended to be delivered either as a two or three day didactic workshop, or a one week didactic and hands-on workshop. The first joint clinical/physics workshop was given in Feb 2004 by Dr. Subir Nag and me at Singapore as part of the Singapore Radiological Society Meeting. The second workshop was funded by the IAEA and held in Peru in Dec 2004, and the physics lectures were given by one of my colleagues. The third workshop was commercially funded and held in Kolkata, India, in November 2007 and was taught by Dr. Nag and myself.

Last updated: March 25/2024