Collaborative Cross mice
(illustrated by Danica Dy)
Collaborative Cross mice is an innovative panel of recombinant inbred mice. They were derived from 8 founder strains (illustrated above) and offer huge genetic and phenotypic diversities. We use Collaborative Cross mice to investigate the genetic basis of epilepsy and its related neurological disorders.
AI-aided epileptic behavior decoding
Combining Deeplabcut and B-SOiD, we are in the process decoding behavior and motor fingerprints of epileptic outcomes.
SUDEP
Our lab hosts Tucker-Davis in vivo electrophysiology solution for behavior and electrophysiology recording and manipulation for studying epileptic and SUDEP mechanisms.
Simultaneous recording of behavior, brain, heart, and respiratory activities in freely moving mouse to reveal physiologic cascade that leads to SUDEP