Published paper in Nucleic Acids Research January 2021

Bappa, Zakk, and Kurt publish a paper in NAR titled, Structural basis of sequestration of the anti-Shine-Dalgarno sequence in the Bacteroidetes ribosome (2021). With collaborators from the Ortega lab at McGill University, Montreal, Quebec we solved the structure of the ribosome from Flavobacterium johnsoniae. Though SD sequences are heavily underrepresented among the Bacteroidetes, with the help of our collaborators at OSU, Elan Shatoff and Ralf Bundschuh, we show bioinformatically that the genes coding for 30S proteins S21 (rpsU) and S18 (rpsR) in many Bacteroidetes have perfect SD sequences upstream of their start codons, suggesting a novel mechanism of autoregulation.

Structural basis of sequestration of the anti-Shine-Dalgarno sequence in the Bacteroidetes ribosome | Nucleic Acids Research | Oxford Academic (oup.com)

Structural basis of sequestration of the anti-Shine-Dalgarno sequence in the Bacteroidetes ribosome – PubMed (nih.gov)

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