Omega 3 and stress

A previous post discussed Omega 3s and anxiety.

While the role of omega 3’s and inflammation has been studied(1), omega 3’s and stress is not as well studied.

This post discusses a study looking at Omega 3’s and stress reduction.

Who was in the study? (2)

138 sedentary, overweight, middle-aged participants (n = 93 women, n = 45 men) received either 2.5 g/d of omega-3, 1.25 g/d of omega-3, or a placebo for 4 months (2).

What was studied? (2)

  • Before and after the trial, participants underwent the Trier Social Stress Test.
  • Saliva and blood samples were collected once before and repeatedly after the stressor to measure salivary cortisol, telomerase in peripheral blood lymphocytes, and serum anti-inflammatory (interleukin-10; IL-10) and pro-inflammatory (interleukin-6; IL-6, interleukin-12, tumor necrosis factor-alpha) cytokines.

What were the results? (2)

  • Adjusting for pre-supplementation reactivity, age, sagittal abdominal diameter, and sex, omega-3 supplementation altered telomerase (p = 0.05) and IL-10 (p = 0.05) stress reactivity; both supplementation groups were protected from the placebo group’s 24% and 26% post-stress declines in the geometric means of telomerase and IL-10, respectively.
  • Omega-3 reduced overall cortisol (p = 0.03) and IL-6 (p = 0.03) throughout the stressor;
  • The group that received 2.5gram per day of Omega 3’s had had 19% and 33% lower overall cortisol levels (lower stress) and IL-6 geometric mean levels (lowering inflammation), respectively, compared to the placebo group.

The authors (2) conclude that, by lowering overall inflammation and cortisol levels during stress and boosting repair mechanisms during recovery, omega-3 may slow accelerated aging and reduce depression risk.

What are some caveats?

  • This is a small study and further study is needed.
  • The population studied was middle aged, which makes it difficult to generalize to specific populations like college students.
  • Omega 3s may interact with prescription medications and supplements.
  • Omega 3’s have other health benefits (3) as well.
  • Talk to your doctor or prescriber before considering omega 3’s.

What are some sources of omega 3s?
According to the National Institute of Health(3), sources of omega 3’s include:
• Fish and other seafood (especially cold-water fatty fish, such as salmon, mackerel, tuna, herring, and sardines)
• Nuts and seeds (such as flaxseed, chia seeds, and walnuts)
• Plant oils (such as flaxseed oil, soybean oil, and canola oil)
• Fortified foods (such as certain brands of eggs, yogurt, juices, milk, soy beverages, and infant formulas)
• Omega-3 dietary supplements include fish oil, krill oil, cod liver oil, and algal oil (a vegetarian source that comes from algae). They come in a wide range of doses and forms.

How much omega 3s do I need per day?
The U.S. Food and Drug Administration recommends consuming no more than 3 g/day of EPA and DHA combined, including up to 2 g/day from dietary supplements (3).

Where can I learn more about omega 3s?

https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/

What are some resources to improve nutrition?
• Nutrition coaching with The OSU Student Wellness Center
• Nutritionist at The OSU Wilce Wilce Student Health center
• Nutritionist at The OSU Wexner medical center
• Nutrition books
• Take a nutrition class
• Take a look at the Dietary Guidelines for Americans.
• Harvard’s page on nutritional psychiatry.

What are some resources to improve stress?

To learn more about stress management go here: https://u.osu.edu/emotionalfitness/2017/09/01/dealing-with-too-much-stress/

 

By R. Ryan S Patel DO, FAPA OSU-CCS Psychiatrist

Disclaimer: This article is intended to be informative only. It is advised that you check with your own physician/mental health provider before implementing any changes. With this article, the author is not rendering medical advice, nor diagnosing, prescribing, or treating any condition, or injury; and therefore claims no responsibility to any person or entity for any liability, loss, or injury caused directly or indirectly as a result of the use, application, or interpretation of the material presented.

References:

  1. Wall R, Ross RP, Fitzgerald GF, Stanton C. Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids. Nutr Rev. 2010 May;68(5):280-9. doi: 10.1111/j.1753-4887.2010.00287.x. PMID: 20500789.
  2. Madison, A.A., Belury, M.A., Andridge, R. et al.Omega-3 supplementation and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults. Mol Psychiatry (2021). https://doi.org/10.1038/s41380-021-01077-2
  3. https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/

Technology, Electronics, and Mental Health

With online classes, distance learning, homework time, and remote work; people are increasingly spending more time with electronic devices and technology than in the past.  This increased screen time for work, school may cause previously used screen time for leisure activities not as restorative; as this may increase total screen time and sedentary behavior.

Zhai and colleague’s review of 24 studies shows that too much screen time (> 6 hours per day) can impact depression (1).  Similar, a review of 31 studies concluded that sedentary behavior may also impact anxiety (2).

More devices are now available than ever before: computers, televisions, tablet pcs, smartphones, smart watches, etc.

While healthy technology use can have benefits of productivity, social connection, entertainment,  and improved health; unhealthy technology use can worsen our distraction,  isolate us socially, increase stress, expose us negative social influences; and negatively impact our health.

The American Psychological Association (3) offers the following strategies to use technology in healthy ways:

  1. Avoid distracted driving (3): APA advises us to turn off notifications and place your phone out of reach when driving.
  2. Avoid electronic devices before bedtime (3). Previous research showed blue light from electronic devices used at bedtime can impact sleep (4), stressful material on electronic devices can also interfere with our ability to fall asleep (3).
  3. When smartphone users turned off smartphone notifications, they reported lower levels of inattention and hyperactivity than they did during weeks when their notifications were turned on (3, 5).  Frequent notifications were also associated with lower levels of productivity, social connectedness and psychological well-being (3,5).
  4. Schedule time for email, when possible. People who checked email continuously reported more stress than those who checked email only three times per day (3, 6).
  5. Manage expectations (3). If possible, schedule time to check messages, email, notifications etc and if possible, let others (family members, boss, etc) know how often you do this, to help manage their expectations.
  6. While social media can help us connect with others, it can also impact feelings of sadness or depression (3, 7), other people may find it helpful. Consider how social media use makes you feel and adjust your use accordingly.
  7. Face to face interactions are important for mental health. The 2017 Stress in America survey found 44 percent of people who check email, texts and social media often or constantly report feeling disconnected from their family, even when they’re together (3). When you’re with friends and family, make an effort to unplug: consider silencing your phone and put it out of reach at dinnertime or during family outings (3).
  8. Disconnect: Instead of grabbing your phone during spare time, disconnect from electronics to reflect, recharge, relax; and collect yourself (3).

To counteract excessive screen time, sedentary behavior from remote work/learning, consider the following:

  • Periodic breaks away from the screen, even a few minutes per hour may help.
  • Stretching, walking during these breaks may be helpful.
  • Instead of mindless “infinite” scrolling, consider your goal before starting a device or program.
  • Consider time outside, in nature and other leisure activities for mental health.
  • Exercise, playing sports can also help address the negative mental health effects of excessive sedentary behavior and screen time.
  • Check out mindful technology use by OSU Digital Flagship

By R. Ryan S Patel DO, FAPA OSU-CCS Psychiatrist

Disclaimer: This article is intended to be informative only. It is advised that you check with your own physician/mental health provider before implementing any changes. With this article, the author is not rendering medical advice, nor diagnosing, prescribing, or treating any condition, or injury; and therefore claims no responsibility to any person or entity for any liability, loss, or injury caused directly or indirectly as a result of the use, application, or interpretation of the material presented.

References:

  1. Zhai L, Zhang Y, Zhang D. Sedentary behaviour and the risk of depression: a meta-analysis. Br J Sports Med. 2015 Jun;49(11):705-9. doi: 10.1136/bjsports-2014-093613. Epub 2014 Sep 2. PMID: 25183627.
  2. Stanczykiewicz B, Banik A, Knoll N, Keller J, Hohl DH, Rosińczuk J, Luszczynska A. Sedentary behaviors and anxiety among children, adolescents and adults: a systematic review and meta-analysis. BMC Public Health. 2019 Apr 30;19(1):459. doi: 10.1186/s12889-019-6715-3. PMID: 31039760; PMCID: PMC6492316.
  3. Ballard D. Connected and content: Managing healthy technology use. American Psychological Association.  https://www.apa.org/topics/healthy-technology-use
  4. https://u.osu.edu/emotionalfitness/2015/07/17/blue-blockers-and-other-ways-to-reduce-electronics-induced-sleep-disruption-and-daytime-tiredness/
  5. Kostadin Kushlev, Jason Proulx, and Elizabeth W. Dunn. 2016. “Silence Your Phones”: Smartphone Notifications Increase Inattention and Hyperactivity Symptoms. In Proceedings of the 2016 CHI Conference on Human Factors in Computing Systems (CHI ’16). Association for Computing Machinery, New York, NY, USA, 1011–1020. DOI:https://doi.org/10.1145/2858036.2858359
  6. Kostadin Kushlev, Elizabeth W. Dunn, Checking email less frequently reduces stress, Computers in Human Behavior, Volume 43, 2015, Pages 220-228, ISSN 0747-5632, https://doi.org/10.1016/j.chb.2014.11.005.

(http://www.sciencedirect.com/science/article/pii/S0747563214005810)

  1. Lin LY, Sidani JE, Shensa A, Radovic A, Miller E, Colditz JB, Hoffman BL, Giles LM, Primack BA. ASSOCIATION BETWEEN SOCIAL MEDIA USE AND DEPRESSION AMONG U.S. YOUNG ADULTS. Depress Anxiety. 2016 Apr;33(4):323-31. doi: 10.1002/da.22466. Epub 2016 Jan 19. PMID: 26783723; PMCID: PMC4853817.

 

Meditation for attention, stress, and anxiety

By R. Ryan S Patel DO, FAPA OSU-CCS Psychiatrist

Life transitions can be times of increased stress and anxiety; which can also impact your attention and focus.  One of those transitions includes moving to campus, preparing for the beginning of the fall semester, adjusting to new routines, campus life, etc.

While there are many strategies to help with the transition process, meditation may be the 1 thing to consider because it can be quick, easy, and has low potential for side effects; and has the potential to benefit everyone.  It is practiced by some of the most successful people in the world.

A review of 13 studies showed improvement in ADHD symptoms with mindfulness meditation (1).

41 trials show mindfulness meditation helped improve stress related outcomes such as anxiety, depression, stress, positive mood, etc. (2)

A review of 14 clinical trials shows meditation being more effective than relaxation techniques for anxiety (3).

What are come caveats?

  • While there are many types of mediation techniques, mindfulness-based meditation is the most studied.
  • Different people may benefit from different types of meditation, and this area is being further researched.
  • Practicing regularly may lead to improved benefits.

How to learn meditation?

  • Various apps, books, videos, classes, and guides may be a useful introduction to meditation.

What else might help improve attention, anxiety, and stress related to the beginning of the semester?

What are some helpful resources?

Disclaimer: This article is intended to be informative only. It is advised that you check with your own physician/mental health provider before implementing any changes. With this article, the author is not rendering medical advice, nor diagnosing, prescribing, or treating any condition, or injury; and therefore claims no responsibility to any person or entity for any liability, loss, or injury caused directly or indirectly as a result of the use, application, or interpretation of the material presented.

References:

  1. Poissant, H., Mendrek, A., Talbot, N., Khoury, B., & Nolan, J. (2019). Behavioral and Cognitive Impacts of Mindfulness-Based Interventions on Adults with Attention-Deficit Hyperactivity Disorder: A Systematic Review. Behavioural neurology2019, 5682050. doi:10.1155/2019/5682050
  2. Goyal M, Singh S, Sibinga EMS, et al. Meditation Programs for Psychological Stress and Well-Being [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2014 Jan. (Comparative Effectiveness Reviews, No. 124.)Available from: https://www.ncbi.nlm.nih.gov/books/NBK180102/
  3. Montero-Marin, J., Garcia-Campayo, J., Pérez-Yus, M., Zabaleta-del-Olmo, E., & Cuijpers, P. (n.d.). Meditation techniques v. relaxation therapies when treating anxiety: A meta-analytic review. Psychological Medicine,1-16. doi:10.1017/S0033291719001600