So, you ask, what will we gain by having this new 600 MHz available?
- Variable temperature – this system will be capable of running experiments from -120C to +100C. The system has a BCU temp accessory, which allow much better temperature stability with moderate changes in temp; ie -20C to +40C.
- Increased signal and peak dispersion for all nuclei. You will notice immediately that your 13C spectra are much improved via sensitivity and signal dispersion. If you have a complex spectrum with a mess of overlapping peaks – this is your NMR. Also note that the CCIC is currently installing a 700 MHz with a 13C direct observe cryoprobe. This system will have incredible 13C signals.
- 24-tube sample changer. After the Bruker engineer is finished running all the specs, I will work on the configuration of this system. Will it be running in automation or manually? I’m not sure yet, but hoping that we can mix the two easily. Check back for updates.
- Water suppression. A 600 MHz spectrometer is usually the ‘go-to’ field for biomolecular samples. You’ll be able to run all sorts of water suppression experiments – 1D and 2D.
There are a few users that will be my ‘test subjects’ in order to optimize the auto vs. manual setup. These folks have already been informed and regularly use the DPX400 and DRX500 for more advanced experiments. The next group to get access will be all DRX500 users. After that, you may request training via FOM. Please indicate your research needs to justify why you’ll need the higher field.