Certain medications cause your skin to become more sensitive to the sun. Contrary to popular belief, they don’t make you more likely to burn, but actually cause a separate type of painful and itchy rash that can look like a bad burn. There are two types of photosensitive reactions: phototoxic and photoallergic.
Phototoxic is the most common. This happens when the drug itself gets dispersed throughout the body and ends up in the skin, where it absorbs UVA light and causes cellular damage. A phototoxic event typically happens within hours of initial exposure to sunlight.
Photoallergic reaction occur when the UV light alters the chemical structure of the drug and the body’s immune system sees this new compound as an intruder and attacks it. A photoallergic reaction doesn’t usually happen right away; it requires longer, and often multiple, exposures to sunlight before it happens.
Many commonly used medicines can cause photosensitivity:
Antibiotics such as ciprofloxacin (Cipro®), levofloxacin (Levaquin®), sulfamethoxazole/trimethoprim (Bactrim®) and doxycycline, tetracycline, and minocycline.
Acne medicines such as (isotretinoin (Accutane®/Claravis®), tazarotene (Tazorac®), and tretinoin)
Medicines to prevent malaria while traveling like atovaquone/proguanil (Malarone®) and chloroquine).
If you are taking a medication that can increase photosensitivity, you should avoid excessive exposure to sunlight and tanning beds. (Of course, you already know that you should avoid tanning beds anyway). If you don’t want to be a shut in while the sun shines, make sure you wear a broad spectrum (UVA/UVB) sunscreen with a SPF rating of 30 or greater. This will decrease that amount of sunlight exposure to your skin and therefore the risk of a bad reaction.
Sun Screen Tips:
- Make sure it is broad spectrum (UVA & UVB)
- Apply roughly one ounce of sunscreen for the full body
- Apply one-half teaspoon of sunscreen to smaller body parts i.e. face/neck, each arm and shoulder
- Apply one teaspoon of sunscreen to larger body parts i.e. legs, back
- Apply 15-30 minutes prior to sunscreen exposure to ensure optimal protection
- If swimming or being physically active use a “water resistant” sunscreen
- Reapply liberally, especially if excessive swimming , sweating or toweling off
- Minimally use a SPF of 15, optimally use a SPF of 30
- If applying insect repellant, put the sunscreen on first, wait 15 minutes and then apply the insect repellant
If you are planning on spending a lot of time in the sun while on a medication, be sure to ask your pharmacist about possible photosensitivity side effects. The pharmacy staff at the Wilce Student Health Center is always willing to answer any questions you may have. Feel free to stop by or call us at (614) 292-0125.
Dean Wagner, PharmD candidate 2012
Student Health Services
The Ohio State University
Jason Goodman, PharmD, RPh
Student Health Services
The Ohio State University
Photos: www.medicine.net