Founders’ Lecture

BME Series Seminar Presents:
Dr. Lawrence Bonassar
“Lessons Learned in a Decade of Printing Cartilage.”
April 12, 2019, 11:00 am to 12:00 pm
245 Bevis Hall

While tissue engineering holds great promise for clinical reconstruction of cartilage for a variety of applications, a great challenge remains in the reliable and scalable generation of tissues that match the desired anatomy and reproduce the microstructure of the tissue that ensures proper function.  Over the past decade our lab has developed an array of platform technologies for co-processing cells and biomaterials to enable larger scale and standardized methods for generating engineered cartilage.  These processes include tissue injection molding, tissue sintering, living lithography, and 3D tissue printing technologies, with  target applications ranging from articular cartilage, ear cartilage, trachea, meniscus, and intervertebral disc.  The focus of this seminar is detailing the development of these processes with particular focus on the critical role that biomaterials play in tissue engineering via rapid prototyping. The talk will also discuss interfacing this tissue production technology with bioreactors for mechanical conditioning and present in vivo studies of the efficacy of these engineered tissues.

Dr. Bonassar joined Cornell University in 2003 after five years on the faculty of the Center for Tissue Engineering at the University of Massachusetts Medical School. He completed postdoctoral fellowships in the Orthopaedic Research Laboratory at the Massachusetts General Hospital and in the Center for Biomedical Engineering at the Massachusetts Institute of Technology. He currently serves on the editorial board of the journal Tissue Engineering. Dr. Bonassar’s research group focuses on the regeneration and analysis of musculoskeletal tissues, including bone and cartilage. The approach involves a multidisciplinary strategy using techniques in biomechanics, biomaterials, cell biology, and biochemistry.