Ohio Vector-Borne Disease Update: August 24, 2020

The Ohio Department of Health (ODH) has been recording mosquito collection data from local partners in order to monitor for diseases transmitted by mosquitoes in Ohio. The ODH worked with partners in Ashland, Athens, Carroll, Clark, Clermont, Crawford, Cuyahoga, Fairfield, Franklin, Hamilton, Hancock, Hocking, Lake, Licking, Lorain, Lucas, Mahoning, Medina, Meigs, Miami, Montgomery, Muskingum, Perry, Pickaway, Portage, Richland, Ross, Scioto, Shelby, Stark, Summit, Tuscarawas, Union, Vinton and Wood counties in order to collect data from around the state.

Please see below for results of pooled mosquito samples tested for West Nile Virus as of 8/21/20:

  • Clark County: 9,365 total mosquitoes tested; 11 positive samples
  • Cuyahoga County: 1,057 total mosquitoes tested; 2 positive samples
  • Fairfield County: 810 total mosquitoes tested; 1 positive sample
  • Franklin County (including Columbus City): 92,773 total mosquitoes tested; 290 positive samples
  • Lake County: 2,826 total mosquitoes tested; 6 positive samples
  • Lucas County: 2,358 total mosquitoes tested; 24 positive samples
  • Richland County: 15,282 total mosquitoes tested; 3 positive samples

The total number of mosquito samples positive with West Nile Virus is now 337. As of 8/21/20, no human cases of West Nile Virus have been reported.

 

The ODH reported 4 cases of La Crosse Virus during the week of 8/17/20, which were Ohio’s first cases of La Crosse Virus for 2020. Cases include:

  • 3 males
  • 1 female
  • All between the ages of 6-15 year, median age: 9 years

The cases were reported in:

  • Carroll County: 1 case
  • Harrison County: 1 case
  • Trumbull County: 1 case
  • Warren County: 1 case

Onset of symptoms for those cases of La Crosse Virus were between 7/4/20-7/11/20. There are several additional suspect cases under investigation.

For additional information, please visit www.odh.ohio.gov/vectorupdate or call the Ohio Department of Health Zoonotic Disease Program (614-752-1029, option 1).

 

Nootkatone a New Active Ingredient Potential Repellent Now Registered by EPA

From the Environmental Protection Agency:

“A new active ingredient, discovered and developed by the Centers for Disease Control and Prevention (CDC), has been registered by the Environmental Protection Agency (EPA) for use in insecticides and insect repellents… the new ingredient, nootkatone, they may repel and kill ticks, mosquitoes, and a wide variety of other biting pests. Nootkatone is responsible for the characteristic smell and taste of grapefruit and is widely used in the fragrance industry to make perfumes and colognes. It is found in minute quantities in Alaska yellow cedar trees and grapefruit skin….Nootkatone can now be used to develop new insect repellents and insecticides for protecting people and pets. CDC’s licensed partner, Evolva, is in advanced discussions with leading pest control companies for possible commercial partnerships… products could be commercially available as early as 2022.”

EPA Press Release: https://www.epa.gov/pesticides/nootkatone-now-registered-epa

CDC Press Release at: https://www.cdc.gov/media/releases/2020/p0810-nootkatone-registered-epa.html

Evolva Press Release at: https://evolva.com/press-releases/evolva-receives-us-epa-registration-for-nootkatone-a-next-generation-protection-against-vector-borne-diseases-spread-by-insects  and https://nootkashield.com/2020/08/evolva-receives-us-epa-registration-for-nootkatone/ and https://nootkashield.com/2020/08/citrus-flavoring-is-weaponized-against-insect-borne-diseases/

Further information regarding this new repellent active ingredient is below.

 

CDC on Nootkatone:

https://www.cdc.gov/os/technology/techtransfer/successstories/nootkatone.htm

 

Other Honorable Mentions of Nootkatone:

https://federallabs.org/successes/success-stories/formulation-of-nootkatone-as-repellent-and-pesticide-products-against

https://www.npr.org/2011/04/18/135468567/repelling-bugs-with-the-essence-of-grapefruit

https://search.proquest.com/openview/97e6624cecab6c1efb69041670bab056/1?pq-origsite=gscholar&cbl=2029999

https://cen.acs.org/articles/94/i14/Nootkatone-tested-mosquito-repellent.html#:~:text=CDC%20researchers%20have%20shown%20that,those%20of%20synthetic%20pesticides%20(J.

 

Studies on Nootkatone (and attached):

http://jme.oxfordjournals.org/content/jmedent/47/6/1123.full.pdf

https://pubmed.ncbi.nlm.nih.gov/22308777/

https://pubmed.ncbi.nlm.nih.gov/22299371/

https://pubmed.ncbi.nlm.nih.gov/20069863/

https://apps.dtic.mil/dtic/tr/fulltext/u2/a512887.pdf

https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1402&context=ent_pubs

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059459/

https://www.researchgate.net/publication/330722622_Insect-Repellent_and_Mosquitocidal_Effects_of_Noreremophilane-_and_Nardoaristolone-Based_Compounds