ITC Calorimeter

 

MicroCal VP-ITC MicroCalorimeter

Measure Thermodynamic Parameters, Binding Affinity of Macromolecule Interactions

 

 

 

  • Working Sample Volume: 1.4 mL (~ 2 mL needed for proper injection without air pocket)
  • Ligand Injection Volume Range: 0.1-279.7 µL
  • Number of Injections: Single Injection Mode up to 500 Consecutive Injections
  • Temperature Range: 2-80 °C
  • Ni-Cr-Mo Alloy Sample Cell: highly resistant to basic solutions, buffers, chlorides
  • Adjustable Stirring Speed

 

 

Select Publications 

Sen, S.; Hendricks, A.L.; Cowan, J.A. Cluster exchange reactivity of [2Fe-2S]-bridged heterodimeric BOLA1-GLRX5. FEBS J. 2020. DOI: 10.1111/febs.15452

Sen, S.; Rao, B.; Wachnowsky, C.; Cowan, J.A. Cluster exchange reactivity of [2Fe-2S] cluster-bridged complexes of BOLA3 with monothiol glutaredoxins. Metallomics 2018, 10, 1282-1290. DOI: 10.1039/C8MT00128F

Yu, Z.; Cowan, J.A. Design of an Artificial Glycosidase – Metallopeptides that Remove H-Antigen from Human Erythrocytes. Angew. Chem. Int. Ed. Engl. 2017, 56, 2763-2766. DOI: 10.1002/anie.201612079