Circular Dichroism Spectrometer

Jasco Circular DichroismJasco J-815 Circular Dichroism Spectrometer

Measure Protein/Peptide Secondary Structures, Chiral Organics

 

  • Wavelength Range: 165 – 1100 nm
  • 6-Cell Sample Holder for Automated Measurements (simultaneous spectra, parallel thermal melts, etc.)
  • Compatible with both 10 mm and 1 mm cuvettes (adapter to hold thinner cuvette provided)
  • Peltier Device Sample Holder for Thermal Scans
    • Temperature Range: 2-100°C
    • Each of the 6 sample holders controlled individually, can operate simultaneously with different thermal parameters

Select Publications 

Creemer, C.; Kilic, H.; Lee, K.S.; Saracoglu, N.; Parquette, J.R. Light-controlled self-assembly of a dithienylethene bolaamphiphile in water. Dalton Trans. 2020, 49, 8846-8849. DOI: 10.1039/D0DT02001J

Wen, J.; Liao, H.; Stachowski, K.; Hempfling, J.P.; Qian, Z.; Yuan, C.; Foster, M.P.; Pei, D. Rational design of cell-permeable cyclic peptides containing a D-Pro-L-Pro motif. Bioorg. Med. Chem. 2020, 28, 115711. DOI: 10.1016/j.bmc.2020.115711

Goyal, V.D.; Sullivan, B.J.; Magliery, T.J. Phylogenetic spread of sequence data affects fitness of consensus enzymes: Insights from triosephosphate isomerase. Proteins: Struct., Funct., Bioinf. 2020, 88, 274-283. DOI: 10.1002/prot.25799

Mason, M.L.; Lalisse, R.F.; Finnegan, T.J.; Hadad, C.M.; Modarelli, D.A.; Parquette, J.R. pH-Controlled Chiral Packing and Self-Assembly of a Coumarin Tetrapeptide. Langmuir 2019, 35, 12460-12468. DOI: 10.1021/acs.langmuir.9b01939

Alexander, J.L.; Thompson, Z.; Yu, Z.; Cowan J.A. Cu-ATCUN Derivatives of Sub5 Exhibit Enhanced Antimicrobial Activity via Multiple Modes of Action. ACS Chem.Biol. 2019, 14, 449-458. DOI: 10.1021/acschembio.8b01087

Goyal, V.D.; Magliery, T.J. Phylogenetic spread of sequence data affects fitness of SOD1 consensus enzymes: Insights from triosephosphate isomerase. Proteins: Struct., Funct., Bioinf. 2018, 86, 609-620. DOI: 10.1002/prot.25486

Chakraborty, S.; Ganguli, S.; Chowdhury, A.; Ibba, M.; Banerjee, R. Reversible inactivation of yeast mitochondrial phenylalanyl-tRNA synthetase under oxidative stress. Biochim. Biophys. Acta, Gen. Subj. 2018, 1862, 1801-1809. DOI: 10.1016/j.bbagen.2018.04.023

Sen, S.; Bonfio, C.; Mansy, S.S.; Cowan, J.A. Investigation of glutathione-derived electrostatic and hydrogen-bonding interactions and their role in defining Grx5 [2Fe–2S] cluster optical spectra and transfer chemistry. JBIC, J. Biol. Inorg. Chem. 2018, 23, 241-252. DOI: 10.1007/s00775-017-1525-5

Pratumyot, Y.; Chen, S.; Hu, L.; Polen, S.M.; Hadad, C.M.; Badjic, J.D Assembly and Folding of Twisted Baskets in Organic Solvents. Org. Lett. 2016, 18, 4238-4241. DOI: 10.1021/acs.orglett.6b01976